Best TWAS P=8.65e-17 · Best GWAS P=6.42e-31 conditioned to 2.15e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | DIRC3 | 0.12 | 0.07 | bslmm | 697 | 0.08 | 2.7e-10 | -6.39 | 7.1 | 1.4e-12 | 0.00 | 1.00 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DIRC3 | 0.12 | 0.01 | blup | 275 | 0.02 | 3.3e-03 | -0.87 | 7.0 | 2.7e-12 | -0.51 | 0.05 | 0.52 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DIRC3 | 0.08 | 0.06 | lasso | 5 | 0.07 | 2.7e-07 | -9.14 | 8.3 | 8.7e-17 | -0.56 | 0.98 | 0.01 | TRUE |