Best TWAS P=1.6e-07 · Best GWAS P=1.26e-09 conditioned to 6.6e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | CREB1 | 0.15 | 0.00 | enet | 7 | 0.00 | 2.8e-01 | -4.5 | -5.2 | 1.6e-07 | -0.50 | 0.16 | 0.36 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAM119A | 0.04 | 0.02 | blup | 51 | 0.03 | 1.0e-06 | -4.3 | 5.2 | 2.2e-07 | 0.64 | 0.03 | 0.92 | FALSE |