[Hub]/) : Traits : Leg predicted mass (right) :

chr3:51,860,817-53,860,103

Best TWAS P=1.66e-09 · Best GWAS P=2.81e-08 conditioned to 0.646

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NT5DC2 0.11 0.05 enet 22 0.04 5.0e-06 3.5 -5.6 2.1e-08 -0.66 0.09 0.89 FALSE
2 GTEx Prostate RFT1 0.39 0.18 enet 17 0.24 1.1e-06 3.0 5.5 3.3e-08 0.49 0.15 0.75 TRUE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM110 0.19 0.13 blup 59 0.13 4.2e-11 4.7 5.4 5.9e-08 0.58 0.04 0.95 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma GLT8D1 0.10 0.01 enet 7 0.03 4.4e-06 5.4 5.3 1.2e-07 0.67 0.00 0.95 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma TMEM110 0.13 0.09 lasso 3 0.10 5.9e-20 4.8 5.2 2.4e-07 0.62 0.06 0.93 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TMEM110 0.24 0.09 blup 59 0.14 1.4e-07 4.7 5.3 1.0e-07 0.59 0.02 0.96 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM110 0.27 0.10 blup 59 0.14 3.0e-15 4.9 5.3 1.4e-07 0.61 0.01 0.99 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SPCS1 0.28 0.04 lasso 2 0.01 4.6e-02 5.4 5.1 2.7e-07 0.98 0.00 0.93 FALSE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TMEM110 0.21 0.10 lasso 4 0.08 2.3e-05 4.7 5.1 2.7e-07 0.54 0.04 0.96 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma GLT8D1 0.22 0.08 lasso 1 0.07 8.5e-09 5.4 5.4 8.0e-08 0.99 0.00 1.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma NISCH 0.06 0.05 lasso 4 0.04 7.5e-06 5.5 5.3 9.0e-08 0.96 0.00 1.00 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma SPCS1 0.15 0.03 lasso 3 0.04 4.3e-05 5.4 5.8 6.0e-09 0.95 0.00 0.95 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM110 0.13 0.06 blup 59 0.08 3.3e-09 3.8 5.5 4.1e-08 0.50 0.62 0.28 FALSE
14 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RFT1 0.31 0.07 blup 45 0.19 1.8e-09 2.6 5.5 3.6e-08 0.48 0.02 0.97 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma SPCS1 0.11 0.00 blup 41 0.01 9.9e-03 -3.2 6.0 1.7e-09 0.53 0.00 0.33 TRUE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TMEM110 0.19 0.10 lasso 5 0.11 2.1e-12 4.8 5.2 1.6e-07 0.45 0.05 0.94 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GLT8D1 0.20 0.05 lasso 1 0.04 1.0e-03 5.4 5.4 8.0e-08 0.99 0.00 0.96 FALSE
18 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMEM110 0.20 0.13 blup 59 0.15 3.0e-10 5.3 5.6 1.8e-08 0.61 0.01 0.99 FALSE
19 The Cancer Genome Atlas Pancreatic Adenocarcinoma TMEM110 0.36 0.05 blup 59 0.08 3.4e-04 4.8 5.3 1.4e-07 0.56 0.02 0.61 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM110 0.20 0.06 blup 59 0.10 1.2e-10 5.3 5.8 8.1e-09 0.65 0.01 0.99 FALSE
21 The Cancer Genome Atlas Soft Tissue Sarcoma TMEM110 0.12 0.07 blup 59 0.12 7.5e-08 5.3 5.5 3.7e-08 0.52 0.02 0.98 FALSE
22 The Cancer Genome Atlas Skin Cutaneous Melanoma RFT1 0.29 0.04 blup 45 0.11 8.2e-04 4.7 5.2 2.0e-07 0.44 0.01 0.79 FALSE
23 The Cancer Genome Atlas Stomach Adenocarcinoma RFT1 0.13 0.05 blup 45 0.10 6.9e-08 5.0 5.4 8.0e-08 0.44 0.01 0.98 FALSE
24 The Cancer Genome Atlas Stomach Adenocarcinoma TMEM110 0.19 0.12 blup 59 0.13 1.6e-09 4.8 5.5 4.1e-08 0.61 0.05 0.94 FALSE
25 The Cancer Genome Atlas Testicular Germ Cell Tumors TMEM110 0.20 0.01 lasso 2 0.09 3.2e-04 5.3 5.4 6.9e-08 0.56 0.01 0.82 FALSE
26 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RFT1 0.29 0.15 blup 45 0.15 6.5e-05 4.1 5.5 4.0e-08 0.43 0.01 0.80 FALSE