Hub : Genes

NT5DC2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1070 0.0530 1.8e-04 0.052 0.038 0.043 0.043 0.041 6.2e-07 1.8e-05 5.0e-06 5.4e-06 8.6e-06
2 GTEx Artery Aorta 0.0790 0.0440 2.6e-03 0.097 NA 0.057 NA 0.059 5.4e-06 NA 4.3e-04 NA 3.4e-04
3 GTEx Breast Mammary Tissue 0.1310 0.0610 3.9e-04 0.122 NA 0.076 NA 0.069 8.1e-07 NA 9.9e-05 NA 2.0e-04
4 GTEx Breast Mammary Tissue (Female) 0.0852 0.0608 4.8e-02 0.084 NA 0.016 NA 0.063 1.8e-03 NA 1.1e-01 NA 5.9e-03
5 GTEx Cells EBV-transformed lymphocytes 0.1770 0.0940 5.5e-04 0.287 NA 0.199 NA 0.285 5.7e-10 NA 4.2e-07 NA 6.6e-10
6 GTEx Cells Transformed fibroblasts 0.3040 0.0890 3.7e-10 0.166 NA 0.182 NA 0.144 1.6e-12 NA 1.3e-13 NA 5.9e-11
7 GTEx Colon Sigmoid 0.0780 0.0510 9.1e-03 0.074 NA 0.057 NA 0.054 1.3e-03 NA 4.5e-03 NA 5.5e-03
8 GTEx Colon Transverse 0.1190 0.0500 6.1e-06 0.182 NA 0.156 NA 0.170 4.6e-09 NA 7.0e-08 NA 1.7e-08
9 GTEx Heart Atrial Appendage 0.0660 0.0360 2.6e-03 0.086 NA 0.050 NA 0.059 1.1e-04 NA 2.8e-03 NA 1.2e-03
10 GTEx Heart Left Ventricle 0.1495 0.0832 5.0e-03 0.025 NA 0.043 NA 0.029 1.6e-02 NA 2.4e-03 NA 1.1e-02
11 GTEx Nerve Tibial 0.0897 0.0438 2.3e-05 0.040 NA 0.049 NA 0.018 8.0e-04 NA 2.1e-04 NA 1.8e-02
12 GTEx Skin Not Sun Exposed Suprapubic 0.2270 0.1180 1.8e-05 0.097 NA 0.077 NA 0.093 5.3e-06 NA 5.3e-05 NA 8.3e-06
13 GTEx Skin Sun Exposed Lower leg 0.2070 0.0860 2.6e-11 0.189 NA 0.175 NA 0.173 1.7e-15 NA 2.0e-14 NA 2.8e-14
14 GTEx Testis 0.1120 0.0560 1.2e-04 0.160 NA 0.113 NA 0.107 1.4e-07 NA 1.0e-05 NA 1.8e-05
15 GTEx Thyroid 0.2050 0.0750 2.2e-08 0.133 NA 0.128 NA 0.130 2.4e-10 NA 5.1e-10 NA 4.0e-10
16 GTEx Whole Blood 0.2870 0.1300 6.2e-06 0.043 NA 0.054 NA 0.029 8.0e-05 NA 9.0e-06 NA 9.6e-04
17 METSIM Adipose 0.2680 0.0718 5.6e-17 0.128 0.091 0.140 0.118 0.140 1.1e-18 1.7e-13 2.2e-20 2.8e-17 2.6e-20
18 ROSMAP Brain Pre-frontal Cortex 0.0828 0.0388 9.1e-06 0.006 0.028 0.015 0.026 0.018 5.6e-02 1.3e-04 4.2e-03 2.2e-04 2.0e-03
19 YFS Blood 0.1641 0.0405 0.0e+00 0.080 0.084 0.111 0.082 0.112 6.0e-25 4.4e-26 1.7e-34 1.7e-25 9.5e-35
20 TCGA Cervical Squamous Cell Carcinoma 0.1790 0.0970 6.2e-03 0.010 -0.001 -0.005 NA -0.003 1.0e-01 3.4e-01 7.8e-01 NA 5.1e-01
21 TCGA Colon Adenocarcinoma 0.0420 0.0280 8.2e-03 0.018 0.028 0.019 NA 0.016 3.1e-02 9.7e-03 2.7e-02 NA 3.9e-02
22 TCGA Lung Squamous Cell Carcinoma 0.0679 0.0443 4.5e-03 0.015 0.008 0.022 NA 0.028 6.9e-03 3.8e-02 1.3e-03 NA 3.7e-04
23 TCGA Prostate Adenocarcinoma 0.0342 0.0216 1.2e-03 0.030 0.028 0.013 NA 0.024 3.8e-04 6.1e-04 1.5e-02 NA 1.4e-03
24 TCGA Thyroid Carcinoma 0.1910 0.0640 6.1e-16 0.192 0.154 0.176 NA 0.185 2.3e-18 8.6e-15 7.5e-17 NA 1.1e-17

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 6.5 10.3 22.8 0.5 -3.1 4.8 4.8 3.5 4.3 4.3 3.6 -3.9 -1.7 3.2 2.9 3.2 3.8 3.6 -0.7 2.5 2.5 2.8 0.2 3.4 0.1 3.0 3.5
Bipolar Disorder or Schizophrenia 9.4 23.0 54.3 -0.3 -5.1 7.4 7.3 5.3 5.7 6.1 5.5 -5.4 -4.0 5.0 4.2 4.5 6.0 5.4 -0.5 4.0 2.5 4.5 1.0 5.2 -0.0 4.8 5.0
Depressed Affect (Nagel 2018) 1.6 3.3 11.5 -2.6 -1.5 0.0 -0.3 1.5 0.6 0.8 1.8 -1.4 0.3 1.9 3.4 3.3 1.3 2.0 1.7 2.1 0.4 2.3 1.1 2.5 1.7 2.2 1.5
Depression (Nagel 2018) 1.6 2.4 5.5 -1.2 -1.6 2.0 1.8 1.5 1.6 2.3 1.7 -1.8 -1.2 1.5 1.6 1.9 2.0 1.7 -0.9 1.7 0.7 0.7 -0.8 2.0 0.1 1.0 1.8
Intelligence (Savage-Jansen 2018) 10.4 32.1 48.6 0.9 6.7 -5.9 -5.4 -6.7 -5.7 -6.2 -6.9 6.5 2.6 -6.2 -6.5 -6.5 -6.8 -7.0 -1.5 -6.2 -2.3 -6.2 -4.6 -6.5 -1.1 -6.2 -6.6
Neuroticism (Nagel 2018) 6.5 15.3 24.4 -2.5 -4.4 3.6 3.2 4.5 3.5 4.0 4.7 -4.2 -2.3 4.5 4.8 4.9 4.5 4.8 1.0 4.0 2.3 4.6 2.5 4.6 1.8 4.4 4.2
Schizophrenia (2018) 6.3 13.0 31.5 -0.7 -4.0 5.6 5.5 4.0 3.9 4.4 4.1 -3.9 -3.7 3.9 3.0 3.1 4.6 4.1 -0.0 3.2 1.1 3.4 1.2 4.0 -0.1 3.8 3.6
Schizophrenia vs Biploar Disorder 0.3 0.4 2.5 -0.7 -0.3 -0.3 -0.7 0.1 -0.8 -0.8 0.1 0.7 -0.0 -0.4 0.4 0.1 0.0 0.2 1.1 0.7 -1.6 0.5 1.1 0.1 -0.2 0.6 -0.7
Worry (Nagel 2018) 14.6 30.8 48.0 -1.8 -6.6 6.8 6.3 6.6 5.6 6.8 6.7 -6.3 -4.7 6.1 5.6 5.9 6.9 6.7 0.3 5.3 3.2 5.6 3.0 5.7 0.7 5.5 6.4
Alzheimer’s Disease (in mother) 0.2 0.3 1.3 -0.3 0.0 -0.0 0.1 0.2 0.5 0.3 0.2 -0.7 -0.6 0.6 0.4 0.4 0.1 0.2 1.1 -0.1 0.7 0.5 0.3 0.6 0.9 0.6 0.5
Alzheimer’s Disease (in father) 0.8 0.9 8.5 -2.9 0.9 -0.7 -0.3 -0.7 -1.1 -1.1 -0.5 1.0 0.2 -0.1 0.1 0.0 -0.5 -0.4 0.7 -0.9 -1.8 -0.2 -0.2 0.6 0.7 0.1 -1.2
Alzheimer’s Disease (including proxy) 0.3 0.5 3.8 -2.0 0.6 -0.2 0.3 -0.1 0.0 -0.2 0.0 0.1 -0.8 0.5 0.4 0.4 0.0 0.1 1.4 -0.7 -0.2 0.4 0.4 1.0 1.4 0.7 -0.2
Crohns Disease (2017) 0.2 0.4 1.5 -1.1 -0.3 0.7 0.3 0.3 0.7 0.3 0.4 -0.1 -1.0 0.3 0.4 0.5 0.4 0.4 -1.2 0.4 -0.2 0.5 0.5 0.8 0.7 0.7 0.3
Irritable Bowel Disease (IBD) 0.9 2.0 11.1 -1.8 -1.1 1.6 1.0 1.2 0.9 1.5 1.3 -1.5 -3.3 1.5 1.1 1.3 1.4 1.3 -0.9 0.4 0.9 1.4 0.3 1.3 1.5 1.5 1.7
Ulcerative Colitis (UC) 1.1 2.2 12.7 -1.7 -1.1 1.2 0.9 1.3 0.5 1.6 1.3 -2.0 -3.6 1.8 1.2 1.4 1.4 1.3 -0.4 0.2 1.2 1.4 -0.1 1.1 1.4 1.4 1.9
Major Depression (MDD) 4.1 5.0 7.5 -1.6 -2.5 2.7 2.7 2.5 2.2 2.3 2.6 -2.7 -1.8 1.8 2.7 2.7 2.7 2.7 -0.2 2.0 0.2 2.3 0.3 2.6 0.3 2.5 2.5
Reaction Time 0.3 0.5 2.4 -0.6 -0.6 -0.5 -0.6 0.6 0.6 0.2 0.6 -0.6 -0.6 0.3 0.9 0.7 0.5 0.7 0.5 -0.5 -0.6 0.9 0.1 0.6 1.5 1.0 0.9
Verbal and Numeric Reasoning (VNR) 10.6 25.4 40.3 0.1 6.2 -5.9 -5.3 -6.2 -5.1 -5.9 -6.3 6.0 2.4 -4.7 -5.6 -5.5 -6.1 -6.3 0.8 -5.7 -1.4 -5.1 -3.2 -5.3 0.5 -5.1 -6.3
Breast Cancer 1.5 3.7 9.0 0.8 2.6 -1.9 -1.3 -2.6 -1.5 -2.0 -2.5 2.4 3.0 -1.0 -1.9 -1.7 -2.3 -2.4 1.2 -1.6 0.2 -2.0 -0.9 -1.7 0.9 -2.1 -2.6
Ovarian Cancer 0.8 1.1 2.6 1.0 -1.2 1.0 1.3 1.3 1.6 1.2 1.3 -1.1 0.9 0.6 0.8 0.7 1.2 1.3 0.3 1.4 1.0 0.5 -1.1 0.5 -1.2 0.4 1.0
Prostate Cancer 1.6 2.2 4.8 -0.6 -1.9 1.1 0.7 1.7 1.2 1.3 1.8 -1.4 -1.0 1.4 2.2 2.0 1.6 1.9 1.5 1.3 0.7 1.5 1.5 1.7 -0.6 1.9 1.6
Age at First Birth 7.0 10.2 17.4 -2.6 3.7 -3.3 -2.6 -3.7 -3.9 -3.3 -3.7 3.4 -0.7 -3.2 -3.1 -2.9 -3.6 -3.7 -1.1 -4.2 -2.9 -3.9 -3.4 -2.8 0.9 -3.2 -3.5
Bipolar Disorder (2011) 10.8 10.4 22.0 -2.1 -3.1 4.4 4.7 3.1 3.7 3.9 3.5 -3.5 -2.2 4.0 3.8 3.9 3.8 3.6 0.9 2.2 1.6 3.3 0.0 4.3 2.4 0.0 3.3
Body Mass Index (BMI) (2010) 1.0 1.4 4.9 -0.4 1.5 -2.2 -1.8 -1.4 -1.2 -1.3 -1.3 1.5 1.3 -0.7 -0.8 -0.7 -1.7 -1.4 0.0 -0.9 -0.1 -1.3 -0.2 -0.9 0.6 -0.9 -1.4
Coronary Artery Disease (CAD) 0.1 0.1 1.2 0.4 0.0 0.0 -0.6 0.2 -0.3 -0.2 0.1 -0.3 -0.8 -0.2 -0.3 -0.4 -0.2 0.2 0.2 0.1 -0.2 -0.1 1.1 -0.5 -0.0 0.0 0.3
Crohns Disease (2012) 0.4 0.6 1.6 -0.3 -0.7 1.1 1.1 0.7 1.3 1.0 0.8 -0.5 -0.8 0.2 0.8 0.9 0.9 0.7 -0.7 0.4 0.3 0.6 0.3 0.9 0.4 1.0 0.7
Mean Putamen Volume 0.4 0.5 3.0 -0.1 -0.4 1.3 1.7 0.3 0.4 0.8 0.5 -0.3 0.4 -0.6 0.5 0.5 0.7 0.5 -1.1 0.5 -0.1 -0.0 -0.8 0.8 -0.1 0.4 0.2
Fasting Glucose 0.6 0.7 3.5 1.9 -0.4 0.9 0.7 0.7 0.3 0.9 0.5 -1.2 -1.2 1.1 -0.1 -0.2 0.3 0.4 0.1 0.7 1.6 0.3 0.6 -0.3 -0.5 0.3 1.0
HbA1C 0.3 0.4 1.6 -0.8 -0.7 -0.6 -0.5 0.6 -0.6 0.2 0.5 -0.4 -1.1 -0.1 0.6 0.5 0.5 0.6 0.3 0.4 -0.7 0.8 1.3 0.4 -0.3 0.8 0.3
HDL Cholesterol 3.2 5.3 20.1 -4.5 3.1 -2.0 -2.0 -3.1 -2.0 -3.0 -2.5 3.6 1.6 -0.3 -0.2 -0.3 -2.3 -2.3 0.7 -2.6 -1.6 -1.0 0.1 0.6 3.6 -0.6 -3.3
LDL Cholesterol 2.4 3.9 10.7 3.0 1.1 -1.5 -1.2 -1.4 -1.1 -0.9 -1.8 1.1 0.6 -2.4 -3.1 -3.0 -1.6 -2.0 -2.1 -1.4 -0.4 -2.6 -1.1 -3.3 -2.3 -2.7 -1.1
Lupus 0.1 0.1 0.8 0.4 -0.1 -0.4 -0.2 0.1 0.2 -0.1 0.1 -0.0 -0.3 0.3 0.3 0.3 -0.0 0.1 0.2 0.9 0.0 -0.1 0.1 0.2 0.1 0.3 0.0
Neuroticism (2016) 2.9 4.1 7.3 -2.1 -2.2 1.9 1.7 1.8 1.5 2.3 2.1 -2.2 -2.5 2.2 2.5 2.7 2.2 2.2 -0.2 1.9 1.3 2.3 0.6 2.5 1.1 2.2 2.2
Primary Biliary Cirrhosis 2.7 3.8 7.2 0.7 2.1 -1.7 -1.6 -2.0 -2.0 -1.9 -2.1 1.9 0.9 -2.7 -2.5 -2.5 -2.1 -2.2 -1.7 -1.6 -1.4 -2.3 -1.5 -2.3 -1.5 -2.3 -2.1
Rheumatoid Arthritis 3.0 4.1 8.8 -0.5 2.3 -1.9 -1.5 -2.2 -2.3 -2.3 -2.2 2.5 0.9 -3.0 -2.0 -2.1 -2.1 -2.2 -1.2 -1.7 -2.8 -2.2 -1.5 -1.8 -1.0 -2.3 -2.5
Schizophrenia (2014) 8.1 17.9 40.4 -0.1 -4.7 6.4 6.1 4.9 4.9 5.3 5.0 -4.8 -3.6 4.4 3.6 3.8 5.4 4.9 0.4 3.6 1.8 4.0 1.4 4.4 -0.7 4.3 4.4
Triglycerides 2.7 4.5 18.7 4.3 -2.6 1.3 1.0 2.4 2.4 2.5 2.1 -3.3 0.3 1.2 0.6 0.7 1.8 1.9 -0.4 3.0 3.5 1.4 0.7 -0.0 -1.5 0.7 3.1
Type 2 Diabetes (T2D) (2012) 2.5 2.8 7.4 0.9 -1.8 0.9 1.3 2.7 1.1 2.4 2.6 -2.3 -1.5 0.7 1.1 1.3 2.2 2.3 -1.3 2.1 1.0 1.4 0.0 1.0 -1.7 1.1 2.3
Ulcerative Colitis 3.8 5.5 10.2 -2.3 -2.5 2.1 1.6 2.5 1.6 2.4 2.6 -2.7 -3.2 2.7 2.6 2.7 2.6 2.6 1.2 1.5 1.1 2.7 1.1 2.4 2.2 2.8 2.8
Blood Eosinophil Count 1.9 14.3 32.6 0.9 3.4 -5.7 -5.1 -3.6 -5.5 -3.9 -3.9 2.7 1.2 -4.6 -3.8 -3.8 -4.3 -3.9 -2.2 -2.6 -2.6 -4.3 -3.2 -4.7 -2.7 -4.6 -2.8
Blood Platelet Count 1.1 13.2 29.6 4.0 3.5 -3.1 -4.0 -3.4 -3.3 -4.6 -4.0 4.4 0.7 -4.0 -4.8 -5.4 -4.2 -4.0 0.2 -3.5 -1.2 -3.2 0.8 -5.2 -0.4 -4.0 -3.8
Blood Red Count 6.4 61.5 102.0 1.3 -9.6 10.0 10.1 9.5 9.0 9.9 9.5 -9.3 -5.6 8.1 6.8 6.8 9.8 9.3 0.7 8.8 2.5 7.9 4.2 7.5 -2.3 7.6 9.2
Blood White Count 0.5 3.6 28.5 5.3 -1.3 1.3 1.6 1.5 1.7 1.8 1.0 -1.8 2.6 -0.5 -1.1 -1.2 1.0 0.9 -1.5 1.8 1.5 -0.4 -0.6 -1.8 -3.6 -1.2 1.7
Heel T-Score 0.4 2.8 19.4 1.1 -0.4 -2.1 -1.3 0.3 -1.4 -1.3 -0.0 1.8 2.1 -2.1 -1.3 -1.8 -0.4 -0.2 1.1 0.4 -3.0 -0.7 2.0 -1.3 -4.4 -0.9 -1.5
BMI 5.0 29.1 74.5 -2.9 6.2 -8.6 -8.3 -6.0 -7.0 -7.0 -6.0 5.7 5.3 -4.7 -3.5 -3.7 -6.9 -5.9 2.3 -5.3 -2.8 -3.6 -2.9 -5.3 0.5 -4.4 -6.1
Height 2.8 53.3 134.6 -7.0 -5.7 4.8 6.0 5.5 6.3 6.2 6.9 -6.0 -2.2 9.3 11.0 11.6 7.5 7.4 1.6 6.9 7.9 7.6 3.8 11.4 7.5 9.0 6.1
Waist Hip Ratio (WHR) 14.8 66.6 125.4 5.5 -10.1 10.1 10.6 10.4 10.1 11.2 10.1 -11.0 -3.3 6.4 5.6 6.2 10.2 9.7 -3.7 8.9 6.7 5.8 -1.1 5.3 -5.7 5.5 10.5
Systolic Blood Pressure 1.9 9.7 19.8 -0.9 3.2 -3.1 -3.2 -3.0 -4.5 -3.2 -3.4 3.0 -1.4 -3.0 -3.8 -3.8 -3.2 -3.4 -1.7 -4.2 -1.0 -3.2 -2.6 -4.3 0.9 -3.8 -2.8
Smoking Status 3.4 8.2 19.4 2.7 2.5 -3.9 -4.3 -2.5 -2.9 -2.8 -2.9 2.0 3.1 -3.7 -2.9 -3.1 -3.4 -2.9 -1.4 -1.8 -0.7 -2.8 -2.0 -4.4 -1.5 -3.2 -2.1
Allergy or Eczema 0.4 1.0 3.7 1.5 -0.8 1.1 1.9 0.9 1.3 1.1 0.8 -1.0 -0.2 1.0 0.2 0.1 1.0 0.8 0.8 1.0 0.6 1.1 1.5 1.0 -0.5 0.8 0.9
Cardiovascular Disease 1.0 3.4 8.3 -0.3 1.7 -2.9 -2.6 -1.7 -2.3 -2.0 -1.9 1.8 -0.0 -2.1 -2.0 -1.9 -1.9 -2.0 0.5 -2.8 0.3 -1.2 -1.6 -2.7 0.1 -1.8 -1.8
Hypothyroidism (self reported) 0.4 0.9 8.0 0.4 0.1 -0.3 -0.3 -0.1 0.2 -1.1 -0.1 1.0 0.9 -0.2 0.1 -0.5 -0.2 -0.1 2.8 0.1 -1.8 0.7 1.7 0.1 -0.9 0.8 -1.1
Respiratory disease 0.2 0.4 1.2 -0.2 -0.3 -0.3 -0.2 0.3 -0.2 0.5 0.5 -0.8 0.8 0.4 1.0 1.0 0.3 0.5 -0.2 0.7 0.0 0.9 0.9 1.1 0.7 0.6 0.8
Type 2 Diabetes (T2D) (2018) 0.8 1.4 5.4 2.3 0.7 -1.6 -1.2 -0.7 -0.9 -1.2 -1.0 0.9 1.5 -1.5 -1.3 -1.5 -1.1 -0.9 0.1 -0.7 0.1 -0.3 0.2 -1.9 -1.7 -1.1 -1.0
Lung FEV1/FVC ratio 2.4 12.2 26.5 -2.8 3.6 -4.4 -4.7 -3.5 -3.6 -4.6 -3.7 4.1 -0.2 -3.5 -3.1 -3.4 -3.9 -3.7 0.2 -5.2 -1.9 -3.3 -2.7 -3.8 -0.4 -3.5 -4.0
Lung FVC 1.5 7.6 19.3 0.7 1.7 -1.2 -2.0 -1.9 -2.6 -1.8 -2.4 1.7 -2.9 -4.4 -3.8 -3.7 -2.1 -2.5 -2.8 -2.7 -3.9 -3.3 -3.1 -3.9 -2.2 -3.3 -1.6
Neuroticism 7.1 17.2 29.1 -2.2 -4.4 3.8 3.7 4.6 4.1 4.3 4.9 -4.5 -2.0 5.0 5.4 5.4 4.6 5.0 1.8 4.0 2.4 5.0 2.2 5.0 1.9 4.8 4.5
Chronotype (morning person) 0.5 1.2 9.4 1.4 -0.2 -1.8 -2.1 0.0 -0.7 0.1 -0.3 -0.7 0.5 0.3 -0.8 -0.6 -0.4 -0.3 1.2 0.5 3.1 -0.3 0.6 -1.7 1.0 -0.7 0.7
Hair Pigment 0.0 0.2 1.1 0.8 0.6 -0.4 0.0 -0.5 -1.1 -0.5 -0.5 0.1 -0.3 -1.0 -0.2 -0.3 -0.5 -0.4 0.6 -0.4 0.5 0.2 -0.3 -0.3 -0.1 0.0 -0.4
Tanning 1.1 12.9 27.3 0.0 4.1 -5.2 -5.0 -4.1 -4.3 -4.5 -4.2 4.2 2.4 -4.3 -3.1 -3.4 -4.5 -4.2 0.8 -3.5 -1.9 -3.1 0.3 -3.6 0.8 -3.0 -4.1
Hand grip strength (left) 1.4 3.7 9.1 -0.8 -1.1 2.4 2.0 1.0 2.9 1.3 1.5 -0.8 1.6 2.8 2.8 2.8 1.6 1.6 1.3 2.2 1.8 1.9 1.5 3.0 1.3 2.3 0.7
Number of treatments/medications taken 0.6 1.1 5.0 0.6 0.8 -1.0 -1.4 -0.6 -1.1 -0.8 -0.9 0.8 0.1 -0.8 -1.3 -1.2 -1.1 -0.9 0.2 -1.2 0.7 -0.8 -1.2 -2.2 -0.9 -1.5 -0.8
Average weekly spirits intake 3.3 4.1 8.3 -1.4 2.5 -2.6 -2.3 -2.7 -2.9 -2.6 -2.5 2.3 1.1 -2.1 -1.6 -1.4 -2.6 -2.5 0.0 -2.6 -0.2 -1.4 -0.9 -1.4 0.4 -1.6 -2.6
Sensitivity / hurt feelings 1.6 2.7 5.4 -0.2 -1.7 2.1 2.3 2.0 1.7 1.8 2.0 -1.7 -1.7 1.9 1.7 1.6 2.0 2.1 0.2 1.5 1.5 1.8 0.7 1.5 -0.0 1.5 1.6
Frequency of depressed mood in last 2 weeks 1.4 1.9 4.9 -1.8 -1.1 1.4 1.4 1.1 0.6 2.1 1.4 -1.7 -1.1 1.1 1.9 2.2 1.5 1.4 -1.4 1.0 0.7 0.4 -1.4 1.6 0.2 0.7 1.7
Hearing difficulty/problems: Yes 0.8 1.2 9.5 -0.1 0.0 -0.5 -0.5 0.0 -0.8 0.1 -0.1 -0.2 0.4 -1.5 -0.7 -0.5 -0.1 -0.1 -3.1 0.6 -1.4 -1.5 -2.1 -0.8 -2.1 -1.3 0.0
Relative age of first facial hair 0.4 0.8 3.1 -0.9 0.6 -0.2 -0.3 -0.6 -1.1 -0.8 -0.6 0.8 -1.4 -1.3 -0.6 -0.6 -0.6 -0.5 -1.8 -0.6 -1.7 -0.5 -0.7 -0.3 -0.5 -0.6 -1.0
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 1.2 -0.4 -0.3 1.0 1.0 0.6 0.7 0.5 0.6 -0.4 0.5 0.1 0.4 0.3 0.4 0.6 -0.9 0.4 -0.6 -0.5 -0.7 0.5 -1.1 0.0 0.5
Ever used hormone-replacement therapy (HRT) 1.7 2.1 8.0 2.4 -1.5 1.3 0.9 1.8 1.7 2.2 1.4 -2.3 -1.0 0.5 -0.0 0.3 1.2 1.3 -1.6 0.9 2.8 0.7 -0.4 -0.9 -0.3 0.2 2.2
Ever had hysterectomy (womb removed) 0.6 0.7 5.1 2.3 -0.5 0.2 0.2 0.5 0.4 0.7 0.2 -1.0 -0.2 -0.1 -0.9 -0.6 0.2 0.1 -0.9 0.6 1.4 -0.3 -1.0 -1.1 -1.3 -0.7 0.8
Systolic blood pressure, automated reading 2.4 7.1 18.0 -1.8 2.8 -2.7 -3.1 -2.5 -4.2 -3.1 -2.9 2.5 -1.5 -2.7 -2.8 -2.9 -2.8 -2.9 -1.1 -3.4 -2.0 -2.3 -1.7 -3.4 1.3 -2.9 -2.4
Eye problems/disorders: Diabetes related eye disease 0.6 0.7 3.5 -0.0 0.6 -0.5 -0.4 -0.5 -1.0 -0.4 -0.5 0.6 0.1 -0.7 -0.7 -0.6 -0.6 -0.6 -1.9 -0.5 -0.8 -1.3 -1.4 -0.9 -1.1 -1.1 -0.6
Angina 0.7 0.9 1.9 -0.3 1.0 -0.7 -0.8 -1.2 -1.0 -1.0 -1.1 1.4 1.0 -0.8 -0.7 -0.8 -1.0 -1.1 0.7 -1.2 -0.9 -1.3 -0.8 -0.9 0.0 -0.9 -1.2
Medication for hormone replacement therapy 1.3 1.4 6.2 2.5 -1.1 1.2 1.0 1.4 1.4 1.5 1.1 -1.4 -0.3 -0.2 -0.3 -0.2 0.9 0.9 -2.0 1.1 0.6 0.4 -0.6 -0.6 -2.3 -0.2 1.3
Vitamin and mineral supplements 1.7 2.3 4.0 1.2 -1.8 1.7 1.7 2.0 1.2 2.0 1.9 -1.9 -1.2 0.8 0.9 0.8 1.9 1.8 -0.0 1.9 -0.2 1.8 1.9 1.1 -0.4 1.4 1.9
Supplements: Zinc 0.4 0.4 3.4 -0.8 -0.1 -0.0 -0.1 -0.1 -0.5 0.1 -0.2 -0.1 -0.3 -0.5 -0.3 -0.1 -0.1 -0.2 -1.4 -0.1 -1.3 -0.7 -1.8 -0.7 -1.0 -0.6 -0.1
Medication: Co-codamol 0.8 0.9 6.1 1.8 -0.9 0.6 0.0 1.0 0.8 0.3 0.8 -0.5 1.7 -0.9 -0.1 -0.2 0.6 0.8 -0.6 1.2 -0.3 -0.3 -1.0 -0.5 -2.5 -0.4 0.5
Medication: Metformin 0.7 1.0 2.4 -0.3 1.0 -1.5 -1.4 -1.1 -1.3 -1.4 -1.1 1.3 0.7 -1.0 -0.7 -0.7 -1.2 -1.1 -0.1 -1.1 -0.6 -0.5 -0.2 -1.1 -0.4 -0.8 -1.2
Diabetes (father) 0.1 0.1 1.3 0.3 -0.1 -0.3 0.1 0.0 0.1 0.4 -0.1 -0.3 0.1 -0.1 -0.3 -0.2 0.1 -0.1 0.4 -0.5 0.0 -0.1 -1.1 -0.4 -0.1 -0.0 0.1
Diabetes (mother) 0.5 0.6 1.5 0.9 -0.9 0.9 1.2 1.0 1.1 1.0 1.0 -0.7 -0.2 0.7 0.3 0.3 1.0 0.9 0.5 0.6 0.5 0.7 0.3 0.6 -1.2 0.7 0.6
Severe depression (siblings) 1.2 1.4 3.6 -0.5 -1.4 1.2 0.8 1.4 1.9 1.3 1.4 -1.2 -0.2 1.2 1.1 1.3 1.3 1.4 -0.7 1.3 1.4 0.3 -1.8 0.7 -0.2 0.4 1.3
Pack years adult smoking proportion 3.0 4.5 11.4 0.6 -2.9 1.9 1.6 3.1 1.9 2.7 2.9 -3.4 -1.3 1.0 1.8 1.8 2.5 2.9 -0.2 2.9 -0.3 2.0 0.3 1.1 -0.7 2.0 3.4
Impedance of leg (right) 7.7 37.1 74.1 5.6 -7.3 7.7 8.1 7.4 8.6 7.3 7.2 -6.3 -2.4 5.5 4.5 4.2 7.6 7.1 -0.1 7.0 4.5 5.2 4.4 5.5 -1.8 5.4 6.9
Leg fat-free mass (left) 1.6 8.3 28.4 -5.3 3.6 -4.6 -4.5 -3.5 -4.0 -3.3 -3.0 2.6 2.5 -1.3 -0.0 0.3 -3.4 -2.8 0.5 -2.4 -0.2 -1.7 -2.3 -0.9 2.9 -1.5 -2.8
Trunk fat percentage 0.5 2.2 6.6 -0.5 -1.3 0.1 0.4 1.5 1.5 1.2 1.5 -1.6 0.2 2.1 1.7 1.5 1.3 1.5 2.6 1.2 1.6 2.2 1.0 1.4 1.2 1.8 1.7
Hand grip strength (right) 1.1 2.9 8.9 -1.4 -0.2 1.2 0.9 0.2 2.0 0.0 0.7 0.4 1.2 2.4 2.3 2.0 0.7 0.9 2.4 1.1 1.5 2.1 3.0 3.0 2.2 2.3 -0.4
Townsend deprivation index at recruitment 1.0 1.3 3.9 -0.2 1.2 -2.0 -1.5 -1.0 -1.7 -0.7 -1.1 0.7 1.2 -1.6 -0.7 -0.6 -1.3 -1.0 -1.5 -0.8 -1.2 -1.4 -1.0 -1.2 0.3 -1.1 -0.7
Current tobacco smoking 0.9 1.4 3.4 1.8 0.9 -1.2 -1.2 -0.9 -0.7 -0.6 -1.0 0.4 1.3 -1.8 -1.4 -1.4 -1.2 -1.1 -1.3 -0.7 -0.7 -1.6 -1.1 -1.8 -1.1 -1.4 -0.5
Average weekly fortified wine intake 0.9 1.1 3.9 -2.0 -0.1 0.1 0.4 0.2 0.9 -0.3 0.5 0.3 0.6 1.6 1.6 1.4 0.5 0.6 1.8 0.4 0.9 1.0 1.0 1.8 1.1 1.2 -0.2
Maternal smoking around birth 0.6 0.9 2.7 0.3 -1.4 1.0 1.1 1.4 1.0 1.3 1.3 -1.5 -0.1 0.1 0.4 0.4 1.3 1.2 -0.6 1.0 -0.9 0.4 0.0 0.4 -0.4 0.6 1.6
Fed-up feelings 1.1 2.0 6.5 -1.2 -1.3 -0.1 -0.5 1.4 0.7 0.9 1.5 -1.3 1.7 1.3 2.5 2.5 1.0 1.6 0.8 2.4 0.8 1.4 0.5 1.3 1.2 1.2 1.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 4.8 -1.8 -0.1 0.7 0.7 -0.0 -0.4 1.0 0.2 -0.4 -0.3 -0.0 0.5 0.9 0.4 0.2 -2.2 0.7 -0.3 -0.9 -1.8 0.5 -0.2 -0.6 0.3
Relative age voice broke 2.9 4.5 7.6 0.2 2.2 -2.4 -2.7 -2.1 -2.1 -2.6 -2.2 2.5 0.3 -2.5 -2.3 -2.3 -2.3 -2.2 -1.8 -2.4 -1.0 -2.2 -1.4 -2.4 -0.4 -2.2 -2.7
Taking other prescription medications 0.4 0.6 3.0 -0.0 -1.2 0.3 0.2 1.2 0.8 0.7 1.1 -0.3 0.5 0.4 0.7 0.7 0.9 1.1 1.0 1.0 0.4 0.4 0.1 0.1 -1.7 0.5 0.5
Age when periods started (menarche) 7.2 17.2 35.0 -2.7 4.9 -5.2 -5.2 -5.2 -4.8 -5.9 -5.0 5.9 0.6 -4.2 -3.0 -3.3 -5.0 -4.8 0.8 -4.5 -4.0 -3.3 0.3 -2.7 1.9 -2.9 -5.6
Bilateral oophorectomy (both ovaries removed) 2.1 2.4 9.8 2.8 -1.9 1.1 0.4 1.9 1.9 1.7 1.7 -2.2 0.3 1.2 0.7 0.9 1.3 1.6 -0.2 1.5 3.1 1.3 -0.3 -0.2 -0.9 0.6 2.2
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 2.3 1.4 -0.6 -1.1 -0.9 0.5 -0.3 -0.4 0.2 0.3 0.7 -0.9 -0.5 -0.7 -0.1 0.1 0.5 0.5 -0.7 -0.1 0.3 -1.3 -1.5 -0.7 0.0
Tinnitus: Yes, but not now, but have in the past 0.8 0.8 3.7 0.1 -0.9 0.4 0.6 1.0 0.2 1.2 1.0 -1.3 -1.9 -0.2 0.8 0.8 0.8 0.9 -0.8 0.7 0.5 0.8 1.1 0.7 -0.2 0.6 1.4
Qualifications: CSEs or equivalent 1.1 1.4 3.7 -0.5 -0.5 0.6 0.9 0.9 0.9 0.9 1.1 -1.2 0.7 1.0 1.6 1.6 0.8 1.2 1.4 1.4 0.3 1.4 1.2 1.7 1.9 1.4 1.3
Serious illness, injury or assault to yourself 2.2 2.7 6.7 1.5 -2.0 2.1 1.8 2.0 2.6 2.1 1.9 -2.1 0.1 1.0 1.1 1.2 1.8 1.8 -0.6 1.7 1.9 0.7 -0.4 0.7 -2.0 0.9 1.9
High blood pressure 1.1 3.1 8.4 -1.6 1.5 -1.9 -2.2 -1.6 -2.2 -2.2 -1.8 2.0 -1.8 -1.6 -1.7 -1.8 -1.6 -1.8 1.4 -2.9 -1.3 -0.7 -0.7 -2.2 1.3 -1.3 -2.0
Hayfever, allergic rhinitis or eczema 1.0 2.2 6.8 1.5 -1.4 2.1 2.6 1.5 1.8 2.0 1.6 -1.9 -0.9 1.4 0.7 0.8 1.6 1.5 -0.2 1.5 0.9 1.5 0.9 1.4 -1.1 1.0 1.6
Multivitamins +/- minerals 3.3 4.1 9.2 0.2 2.3 -2.7 -2.6 -2.4 -1.3 -2.5 -2.3 2.2 3.0 -1.9 -1.4 -1.4 -2.6 -2.3 -0.1 -1.9 -0.8 -2.4 -2.1 -1.8 0.1 -2.1 -2.2
Stomach or abdominal pain in last month 4.6 5.7 9.7 0.3 -2.8 3.1 2.8 3.1 2.6 3.1 3.1 -3.0 -1.3 2.5 2.3 2.5 2.9 3.0 -0.5 2.8 1.2 1.9 -0.2 2.0 -0.7 2.0 2.8
Supplements: Glucosamine 0.3 0.4 2.3 0.5 0.1 -0.8 -1.0 -0.1 -0.7 -0.4 -0.2 -0.0 0.7 -1.2 -0.2 -0.2 -0.4 -0.2 -0.2 0.0 -0.1 -0.6 -1.2 -1.0 -1.5 -0.8 -0.1
Diverticular disease/diverticulitis (self-reported) 0.6 0.8 4.0 1.7 -0.8 0.8 0.7 0.6 1.2 0.8 0.5 -0.6 0.6 -0.4 -0.5 -0.4 0.5 0.4 -1.6 0.7 0.4 -0.9 -0.4 -0.3 -2.0 -0.6 0.7
Medication: Atenolol 0.3 0.4 2.4 1.0 0.1 -0.3 -0.4 -0.1 0.2 -0.5 -0.3 0.7 0.2 -0.3 -0.9 -1.2 -0.3 -0.4 1.5 -0.9 -0.3 -0.1 0.8 -1.1 -0.1 -0.4 -0.3
Medication: Levothyroxine sodium 0.8 1.3 6.6 -0.9 0.9 -1.2 -1.2 -0.7 -0.7 -1.9 -0.8 1.7 0.4 -0.9 -0.4 -0.9 -0.9 -0.7 2.2 -0.7 -2.6 -0.4 1.0 -0.1 -0.3 0.3 -1.7
Sitting height 1.5 10.7 32.5 -4.9 -1.4 1.6 2.0 1.2 1.6 2.2 2.1 -2.4 -0.9 4.7 5.2 5.7 2.4 2.4 0.3 2.9 4.0 2.7 1.1 5.2 5.7 3.5 2.4
Chronic bronchitis/emphysema (father) 0.1 0.2 1.0 -0.5 -0.1 0.2 0.6 0.1 -0.2 0.1 0.1 0.1 -0.6 -0.1 -0.0 -0.2 0.4 0.2 -0.3 -0.2 -1.0 0.1 0.6 0.5 0.8 0.2 0.1
High blood pressure (mother) 2.4 3.3 5.8 0.5 -2.2 2.4 1.9 2.2 2.1 2.4 2.1 -2.2 -0.6 2.1 1.6 1.8 2.2 2.1 0.2 2.0 2.4 1.8 0.2 0.9 0.3 1.5 2.2
Body mass index (BMI) 3.0 13.0 33.2 -2.0 3.9 -5.6 -5.8 -3.7 -4.8 -4.3 -3.9 3.2 2.8 -3.6 -2.8 -2.9 -4.5 -3.9 1.3 -3.5 -2.2 -2.6 -2.8 -4.3 0.2 -3.3 -3.5
Impedance of leg (left) 8.2 39.9 76.2 5.2 -7.7 8.2 8.5 7.6 8.7 7.7 7.5 -6.7 -2.8 5.7 4.7 4.5 7.9 7.4 -0.8 7.1 4.4 5.3 4.0 5.8 -1.9 5.6 7.2
Leg predicted mass (left) 1.6 8.3 29.1 -5.4 3.6 -4.7 -4.5 -3.5 -4.0 -3.3 -3.0 2.6 2.5 -1.3 0.0 0.3 -3.4 -2.8 0.5 -2.4 -0.2 -1.7 -2.3 -0.9 2.8 -1.5 -2.9
Trunk fat mass 0.3 1.2 4.9 -2.1 -0.0 -1.2 -0.9 0.2 0.1 0.0 0.4 -0.6 1.1 1.4 1.5 1.5 0.1 0.5 2.2 0.4 1.4 1.3 0.0 1.0 1.9 1.1 0.5
Waist circumference 0.2 0.8 5.6 -0.8 -0.8 -0.0 0.1 1.1 0.3 1.2 1.0 -1.8 0.3 0.4 0.4 0.6 0.7 0.9 -0.1 0.7 0.7 0.5 -2.4 -0.4 -0.8 0.1 1.5
Number of incorrect matches in round 4.3 7.2 13.5 -0.0 -2.5 2.9 2.3 2.6 2.8 2.3 2.7 -2.4 -1.5 3.2 3.0 2.8 2.7 2.8 2.8 2.1 2.0 3.7 3.1 3.1 2.6 3.3 2.8
Past tobacco smoking 2.8 5.1 10.8 -1.9 -2.4 3.3 3.3 2.2 2.4 2.5 2.4 -2.1 -2.5 2.9 1.9 2.2 2.7 2.4 0.6 1.5 0.7 2.0 1.1 2.9 1.0 2.3 2.1
Alcohol usually taken with meals 1.6 2.6 7.7 1.2 -1.4 2.1 1.8 1.4 2.8 1.4 1.5 -0.9 1.5 2.1 1.5 1.4 1.5 1.5 0.5 1.8 2.5 1.1 1.7 1.7 -0.5 1.6 1.0
Nervous feelings 8.0 15.0 27.0 -0.9 -4.2 5.2 5.1 4.2 3.6 4.8 4.4 -4.3 -3.8 4.6 3.7 4.0 4.7 4.4 -0.3 3.6 2.3 3.9 1.8 4.2 0.7 3.8 4.2
Frequency of tenseness / restlessness in last 2 weeks 5.3 8.2 17.0 -1.8 -3.3 2.6 2.3 3.2 2.6 3.4 3.5 -3.3 -1.5 3.1 4.0 4.1 3.2 3.5 0.3 3.0 1.7 2.8 1.2 3.1 1.1 3.0 3.4
Hearing difficulty/problems with background noise 0.8 1.3 3.4 -1.0 -1.1 1.2 1.2 1.3 0.5 1.6 1.4 -1.8 -1.2 0.4 0.9 1.1 1.2 1.3 -1.8 1.2 -0.2 0.4 -0.9 1.1 -0.7 0.6 1.6
Hair/balding pattern: Pattern 2 0.9 1.1 9.7 -0.6 0.3 -1.2 -1.3 -0.4 -0.4 -1.1 -0.3 1.1 2.1 0.7 1.1 0.8 -0.5 -0.1 3.1 -0.1 0.7 0.4 1.0 0.4 0.3 0.7 -1.1
Had menopause 0.3 0.3 1.3 -0.0 0.2 -0.1 -0.5 -0.3 -0.5 -0.5 -0.5 0.4 -0.6 -1.0 -0.8 -0.9 -0.4 -0.5 -0.5 -0.7 -0.9 -0.5 -0.2 -1.2 -0.3 -0.4 -0.4
Had other major operations 0.3 0.4 3.5 1.0 -0.3 0.3 0.4 0.5 1.1 0.6 0.4 -0.7 0.5 0.2 0.2 0.4 0.3 0.4 -0.1 -0.4 1.9 0.1 -0.8 -0.3 -0.4 -0.0 0.6
Forced vital capacity (FVC) 0.7 2.6 5.7 -2.0 -1.4 1.8 1.8 1.2 1.0 1.8 1.5 -1.6 -2.2 1.5 2.0 2.4 1.8 1.6 -1.2 1.5 0.9 0.9 0.1 2.1 1.3 1.5 1.7
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 5.3 2.0 -0.8 -0.7 -0.6 0.9 -0.1 -0.2 0.5 -0.0 0.6 -1.0 -0.5 -0.9 0.2 0.4 0.5 0.5 -0.7 0.1 -0.1 -1.4 -2.3 -0.6 0.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.6 0.5 -0.0 0.0 -0.1 0.2 0.5 0.6 0.1 -0.4 0.0 -0.0 -0.6 -0.3 -0.0 -0.0 -1.0 0.3 -0.0 -0.5 -1.3 -0.6 -1.2 -0.7 0.2
Qualifications: None of the above 0.5 1.0 6.6 -1.0 0.3 -2.2 -2.6 -0.3 -2.2 -0.7 -0.3 0.0 -0.2 -0.8 0.6 0.5 -0.7 -0.2 0.4 0.2 -0.8 0.6 1.1 -0.1 1.6 0.3 0.2
Financial difficulties in last 2 years 0.6 0.8 5.4 1.4 -0.6 0.3 0.5 0.8 0.9 0.8 0.8 -0.7 1.8 -0.4 0.6 0.6 0.5 0.8 -0.4 1.1 0.2 -0.3 -1.3 -0.0 -2.3 -0.0 0.6
Mouth/teeth dental problems 0.6 0.9 4.0 -0.7 1.0 -0.5 -0.8 -1.0 -0.5 -1.2 -1.0 1.3 0.3 -0.3 -0.7 -0.8 -1.0 -1.0 1.2 -2.0 0.7 -0.8 -0.8 -1.0 -0.2 -0.9 -1.5
Heart attack 0.9 1.2 5.0 0.6 0.7 -1.4 -1.5 -0.6 -0.1 -1.5 -0.8 1.6 1.4 -0.3 -1.1 -1.5 -0.8 -0.8 2.2 -0.7 -0.2 -0.8 1.4 -1.0 0.2 -0.8 -1.1
Allergy 1.5 3.4 6.4 -1.1 1.8 -1.9 -2.5 -1.9 -1.7 -2.5 -2.0 2.4 1.3 -1.8 -1.6 -1.6 -2.0 -2.0 0.0 -1.7 -1.1 -2.3 -1.6 -2.1 0.9 -1.8 -2.2
Pain all over the body in last month 1.4 1.6 2.8 -0.3 -1.6 0.5 0.3 1.5 1.7 1.6 1.6 -1.5 0.2 1.6 1.3 1.4 1.3 1.5 -0.3 1.2 0.1 1.5 0.9 1.3 0.9 1.5 1.6
Diabetes (self-reported) 1.5 2.3 5.0 0.7 1.3 -2.2 -2.2 -1.3 -1.5 -1.7 -1.5 1.4 0.6 -1.9 -1.6 -1.8 -1.7 -1.5 -0.5 -1.7 -1.7 -1.2 -0.7 -2.2 -0.7 -1.6 -1.3
Hayfever/allergic rhinitis (self-reported) 1.4 1.9 3.7 0.2 -1.6 1.9 1.9 1.5 1.6 1.6 1.5 -1.4 -1.8 1.8 0.7 0.7 1.7 1.4 0.1 1.0 0.8 1.5 1.5 1.2 0.4 1.3 1.4
Medication: Ramipril 0.4 0.6 1.5 -0.5 0.7 -1.2 -1.0 -0.5 -0.7 -1.0 -0.5 1.1 0.9 -0.7 -0.4 -0.6 -0.6 -0.5 0.1 -0.8 -1.1 -0.8 0.2 -0.6 -0.7 -0.5 -0.9
Medication: Simvastatin 0.4 0.6 3.0 -0.7 0.5 -0.9 -0.9 -0.4 -0.6 -0.5 -0.5 0.4 -0.9 0.2 -0.4 -0.5 -0.5 -0.4 1.0 -0.9 1.1 0.8 1.3 -0.5 1.7 0.0 -0.4
Fluid intelligence score 6.6 13.7 21.5 0.8 4.6 -4.3 -3.3 -4.5 -3.3 -4.1 -4.6 4.3 2.4 -3.6 -4.0 -3.9 -4.4 -4.6 -0.0 -4.0 -1.0 -4.1 -3.7 -3.8 -0.7 -4.1 -4.6
Illnesses of siblings 0.3 0.4 2.2 1.3 -0.1 0.1 0.1 0.4 0.8 -0.1 0.3 -0.4 1.5 -0.0 0.2 0.0 0.0 0.3 1.2 1.1 0.6 0.3 0.3 0.3 -1.0 0.1 0.2
Neuroticism score 3.6 7.4 16.9 -2.2 -2.8 2.1 2.0 3.0 2.0 2.8 3.2 -2.9 -1.3 3.3 4.0 4.1 2.9 3.4 0.9 2.9 1.9 3.1 0.8 3.3 1.3 3.0 2.9
Weight 0.9 4.5 16.0 -4.0 2.4 -3.9 -3.7 -2.2 -2.9 -2.4 -2.0 1.5 2.4 -0.8 0.3 0.5 -2.4 -1.8 0.9 -1.4 0.2 -0.9 -1.8 -0.8 2.3 -0.9 -1.8
Impedance of arm (right) 8.0 37.5 73.6 3.0 -6.9 7.8 8.6 6.8 8.1 7.3 7.0 -6.1 -2.9 6.6 5.2 5.2 7.7 7.0 0.9 6.0 4.7 5.6 4.8 7.0 0.5 6.1 6.7
Arm fat percentage (right) 0.5 1.8 6.2 -1.2 1.3 -2.5 -2.3 -1.1 -1.6 -1.5 -1.1 0.8 1.9 -0.6 -0.5 -0.6 -1.5 -1.1 2.4 -1.5 -0.1 -0.1 -0.9 -1.3 0.7 -0.7 -0.9
Trunk fat-free mass 1.5 8.6 30.8 -5.6 3.7 -4.2 -4.1 -3.7 -4.2 -3.3 -3.2 2.9 2.2 -1.7 0.0 0.5 -3.3 -2.9 -1.2 -2.3 -0.4 -2.3 -2.8 -0.9 2.3 -1.8 -3.2
Hip circumference 1.9 8.3 17.9 -3.1 3.7 -4.2 -4.2 -3.5 -3.6 -3.7 -3.4 2.9 2.0 -2.1 -1.7 -1.7 -3.7 -3.3 1.1 -2.9 -1.7 -1.9 -2.0 -2.3 2.0 -2.3 -3.1
Time employed in main current job 0.7 0.8 2.5 0.2 0.9 0.2 0.2 -0.8 -1.2 -0.2 -0.9 0.6 0.0 -0.4 -1.6 -1.4 -0.7 -0.9 -0.4 -1.4 0.6 -1.1 -1.2 -1.2 0.0 -1.4 -0.7
Alcohol intake versus 10 years previously 2.4 3.6 7.4 0.1 2.0 -2.7 -2.4 -2.0 -2.5 -2.3 -2.1 2.1 0.3 -2.7 -1.9 -2.1 -2.2 -2.1 0.7 -2.1 -1.5 -1.6 0.3 -1.7 -0.2 -1.6 -2.0
Father’s age at death 0.2 0.2 1.3 0.2 0.3 0.6 1.1 -0.4 0.4 0.3 -0.3 -0.1 -0.2 0.3 0.1 0.2 -0.1 -0.2 -1.1 -0.1 -1.0 -0.2 -0.3 0.5 0.6 0.1 -0.1
Worrier / anxious feelings 10.0 19.0 37.1 -0.6 -5.3 6.1 5.1 5.2 5.2 5.0 5.3 -4.4 -2.9 4.9 4.3 4.3 5.5 5.2 0.8 4.4 3.0 4.2 2.5 4.3 0.1 4.2 4.7
Frequency of tiredness / lethargy in last 2 weeks 3.1 5.1 11.4 0.6 -2.7 2.0 1.8 2.8 2.0 3.0 2.8 -3.0 -0.4 1.9 2.7 3.0 2.6 2.8 -0.9 3.4 2.3 1.7 -0.6 1.5 -0.4 1.6 3.0
Falls in the last year 0.9 1.2 8.6 2.3 -0.4 0.7 0.9 0.7 -0.0 1.2 0.5 -1.4 -0.6 -1.1 -0.8 -0.6 0.3 0.3 -2.9 0.6 0.6 -0.3 -0.8 -1.1 -1.4 -0.8 1.1
Hair/balding pattern: Pattern 3 0.5 0.7 1.7 0.5 1.0 -0.9 -0.8 -0.7 -0.6 -0.5 -0.9 0.5 0.4 -1.0 -1.3 -1.3 -0.8 -0.9 -0.9 -0.9 0.4 -1.2 -0.5 -1.2 -0.0 -1.0 -0.5
Number of live births 0.2 0.3 1.7 1.3 -0.1 0.2 0.3 0.1 0.1 0.1 -0.0 0.3 0.6 -0.6 -0.8 -0.9 0.1 -0.0 0.3 0.4 0.3 -0.3 1.3 -0.6 -1.3 -0.3 -0.1
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 6.4 -2.5 -0.2 0.4 0.4 0.0 -0.0 0.4 0.2 -0.2 -2.0 0.4 0.8 1.1 0.4 0.2 -1.2 -0.2 0.4 -0.4 -1.0 0.7 1.2 0.1 0.4
Pulse rate 5.5 9.3 17.7 1.7 -3.6 4.2 3.9 3.6 3.8 4.1 3.6 -3.8 -1.2 2.7 2.4 2.6 3.6 3.5 -1.2 3.4 2.1 2.6 0.6 2.7 -1.9 2.5 3.7
Happiness 3.3 4.1 10.2 -2.1 -1.4 1.3 1.4 1.6 1.6 1.7 1.9 -1.2 -0.5 2.5 2.9 3.0 1.8 2.0 1.6 1.8 0.9 2.5 2.5 3.2 2.1 2.8 1.4
Noisy workplace 0.6 0.8 2.5 -0.1 1.0 -1.0 -1.0 -0.9 -0.8 -1.1 -1.0 0.9 -0.5 -1.0 -1.0 -1.1 -1.0 -1.0 -0.6 -1.0 -1.6 -0.4 -0.2 -0.8 0.2 -0.7 -0.8
Qualifications: A levels/AS levels or equivalent 1.3 2.9 6.3 -0.9 2.3 -0.9 -0.6 -2.4 -0.8 -2.0 -2.3 2.5 0.5 -0.9 -1.7 -1.6 -2.0 -2.3 1.0 -2.2 -0.1 -2.2 -1.6 -1.2 0.7 -1.8 -2.5
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 2.3 0.0 -1.0 1.5 0.9 1.1 1.4 1.1 1.1 -0.9 -0.2 0.9 0.7 1.1 0.9 1.0 -0.8 0.9 1.2 0.3 -0.7 0.9 -0.8 0.6 0.7
Mouth/teeth dental problems: Dentures 0.2 0.3 2.4 -0.3 0.5 -1.1 -1.1 -0.5 -1.5 -0.5 -0.5 0.2 0.2 -0.9 -0.1 -0.1 -0.5 -0.4 -0.2 0.1 -0.6 -0.3 0.4 -0.5 0.1 -0.3 -0.0
Asthma 0.1 0.1 1.0 0.3 -0.0 -0.4 -0.5 0.2 -0.1 0.3 0.2 -0.5 1.0 -0.1 0.4 0.3 -0.0 0.3 -0.3 0.0 0.1 0.2 -0.2 0.1 -1.0 -0.0 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 4.1 -0.8 1.0 -0.7 -0.6 -1.0 -0.9 -0.3 -0.8 0.7 0.7 0.3 0.0 0.3 -0.9 -0.8 0.3 -0.9 2.0 -0.3 -0.3 -0.2 1.5 -0.3 -0.5
Medication: Cholesterol lowering 1.4 2.1 4.9 -0.4 1.3 -2.0 -2.2 -1.4 -1.4 -1.9 -1.5 2.1 0.1 -0.6 -1.3 -1.5 -1.6 -1.5 1.4 -1.8 -0.3 -0.4 1.2 -1.5 1.5 -0.8 -1.8
Depression (self-reported) 3.1 3.7 8.0 -1.5 -1.9 2.5 2.1 2.2 2.0 2.1 2.4 -1.5 -0.2 2.3 2.8 2.8 2.3 2.5 1.0 1.6 1.4 1.6 0.4 1.9 -0.2 1.9 1.6
Medication: Lansoprazole 0.9 1.0 3.3 0.3 -1.4 1.6 1.3 1.1 1.5 1.2 1.1 -0.9 -0.5 1.0 0.5 0.7 1.2 1.0 -0.6 1.0 1.8 0.6 -0.7 0.3 -0.8 0.4 0.8
Prospective memory result 6.4 7.8 12.9 -0.2 -3.2 2.8 2.7 3.0 2.4 3.3 3.2 -3.1 -1.0 3.0 3.3 3.4 3.2 3.3 0.3 3.6 1.7 2.9 2.6 3.4 0.8 3.2 3.3
Lung cancer (father) 0.2 0.3 1.2 0.1 -0.4 1.1 0.8 0.4 0.9 0.3 0.4 -0.4 -0.1 0.8 0.5 0.4 0.4 0.4 1.1 -0.0 -0.2 0.5 0.1 0.4 0.0 0.3 0.4
Illnesses of mother 2.5 3.1 5.5 0.6 2.1 -1.7 -1.3 -2.1 -1.5 -1.9 -2.1 2.1 1.8 -2.0 -1.8 -2.0 -2.0 -2.0 -0.6 -1.6 -1.3 -2.3 -1.2 -1.5 -1.1 -2.0 -2.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 4.2 -2.1 -0.3 0.8 0.6 0.1 -0.1 0.6 0.3 -0.3 -2.0 0.1 0.7 0.9 0.5 0.3 -1.3 -0.2 0.5 -0.3 -1.2 0.5 0.5 0.1 0.5
Pulse wave Arterial Stiffness index 0.6 0.8 2.0 -0.1 0.5 -0.8 -1.0 -0.7 -0.7 -0.8 -0.8 0.3 -0.4 -0.9 -1.1 -1.0 -0.8 -0.9 -1.1 -1.3 -0.5 -0.9 -1.4 -1.3 -0.1 -1.1 -0.4
Impedance of arm (left) 8.5 39.1 72.4 2.8 -7.0 7.8 8.5 6.9 8.2 7.4 7.1 -6.2 -3.1 7.0 5.4 5.4 7.7 7.1 0.9 6.2 4.5 6.0 5.2 7.3 1.1 6.4 6.9
Arm fat mass (right) 0.8 3.1 10.9 -2.5 1.9 -3.3 -3.1 -1.7 -2.4 -2.0 -1.7 1.2 2.1 -1.0 -0.4 -0.4 -2.0 -1.6 1.8 -1.6 -0.2 -0.6 -1.6 -1.4 1.2 -1.1 -1.5
Trunk predicted mass 1.6 8.9 32.2 -5.7 3.8 -4.3 -4.1 -3.8 -4.3 -3.4 -3.2 3.0 2.3 -1.8 0.0 0.4 -3.4 -3.0 -1.2 -2.3 -0.5 -2.4 -2.8 -0.9 2.4 -1.8 -3.3
Standing height 2.0 19.7 54.8 -4.6 -3.0 3.1 4.0 2.8 3.9 3.9 3.9 -3.4 -0.5 6.0 6.7 7.3 4.3 4.2 -0.9 4.4 5.5 3.5 1.7 7.4 4.5 5.0 3.6
Length of working week for main job 1.3 1.5 5.3 -2.0 1.3 -1.9 -1.5 -1.2 -1.9 -1.5 -1.0 1.4 2.3 -0.4 0.3 0.2 -1.2 -0.9 0.9 -0.7 -0.8 -0.7 -0.7 -0.1 0.7 -0.4 -1.4
Exposure to tobacco smoke at home 0.3 0.3 2.0 -1.1 0.3 -0.1 -0.3 -0.1 0.3 -0.2 0.1 0.3 1.4 0.3 0.8 0.7 -0.1 0.2 0.3 -0.0 -0.4 0.6 -0.3 0.9 1.1 0.5 -0.2
Breastfed as a baby 1.9 2.4 7.5 -0.8 2.0 -1.8 -1.5 -1.8 -1.3 -1.8 -1.8 1.5 -0.6 -2.2 -1.2 -1.4 -1.8 -1.7 0.1 -2.4 -2.7 -1.0 -0.0 -0.9 1.0 -0.9 -1.5
Tense / ‘highly strung’ 3.9 6.5 10.4 -2.8 -2.7 3.1 3.2 2.6 2.2 3.1 2.9 -2.4 -2.2 3.0 2.9 3.2 3.2 2.9 0.5 1.9 1.4 2.5 0.8 3.0 1.2 2.7 2.2
Seen doctor (GP) for nerves, anxiety, tension or depression 3.7 5.6 10.9 -1.2 -2.3 3.3 3.3 2.3 2.4 3.0 2.5 -2.6 -1.4 3.2 2.6 2.9 2.6 2.5 0.5 2.1 1.8 2.6 0.0 2.5 1.2 2.4 2.5
Hair/balding pattern: Pattern 4 0.6 1.3 6.0 1.0 0.8 -2.3 -2.5 -1.0 -0.3 -1.7 -1.0 1.0 1.6 -1.3 -0.6 -0.7 -1.4 -1.1 1.0 -1.0 0.3 -0.4 0.0 -1.2 0.4 -0.8 -0.9
Birth weight of first child 0.3 0.5 2.5 -0.3 -0.1 0.8 1.6 0.4 0.9 0.6 0.5 -0.4 -0.2 0.6 0.6 0.6 0.7 0.6 0.7 0.1 1.2 0.5 0.3 1.2 0.6 0.9 0.3
Peak expiratory flow (PEF) 0.3 0.6 6.9 -2.6 0.4 -0.8 -0.6 -0.6 -0.5 -0.4 -0.3 0.4 -0.5 -0.0 0.8 0.9 -0.2 -0.3 -0.1 -0.5 -0.3 -0.3 -0.8 0.7 1.3 0.1 -0.3
Pulse wave reflection index 3.7 4.5 9.4 -2.1 2.3 -3.1 -2.8 -2.4 -2.8 -2.5 -2.4 2.3 1.3 -2.0 -1.6 -1.4 -2.5 -2.4 0.6 -2.9 -0.6 -1.8 -1.8 -1.9 0.5 -1.7 -2.6
Ever highly irritable/argumentative for 2 days 5.1 6.1 10.4 0.1 2.6 -3.2 -3.2 -2.5 -2.1 -2.7 -2.6 2.4 1.8 -2.8 -2.4 -2.3 -3.0 -2.6 -0.8 -2.2 -1.1 -3.0 -2.8 -2.8 -1.6 -3.0 -2.6
Loud music exposure frequency 0.5 0.5 5.3 -0.6 -0.4 1.1 0.7 0.3 0.3 0.6 0.3 -0.3 -2.3 0.4 -0.3 -0.2 0.6 0.3 -1.0 0.1 -1.0 0.5 -0.2 0.2 0.7 0.3 0.4
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 5.7 -1.5 -0.1 0.8 1.6 -0.1 1.2 0.1 0.2 0.1 -0.2 0.8 0.7 0.8 0.5 0.2 2.4 -0.1 0.5 0.5 -0.5 1.2 1.0 0.8 -0.4
Mouth/teeth dental problems: Bleeding gums 5.8 7.5 13.1 0.8 -3.4 3.3 3.4 3.6 3.1 3.2 3.5 -3.1 -2.0 2.0 2.3 2.2 3.6 3.5 -1.1 3.6 0.2 2.8 1.0 2.7 -1.2 2.7 3.0
Blood clot in the leg (DVT) 1.8 2.3 4.9 0.1 -1.8 0.9 1.6 1.8 1.1 1.8 1.9 -1.6 -0.7 1.4 2.2 2.1 1.9 2.0 0.3 1.1 0.7 1.5 0.8 1.7 -1.4 1.7 1.7
Medication: Paracetamol 3.1 5.1 10.2 1.4 -2.6 3.0 2.4 2.7 2.5 3.1 2.6 -3.2 -0.7 1.8 1.7 2.1 2.7 2.6 -1.7 2.6 2.7 1.6 -0.9 1.3 -1.3 1.5 2.9
Headache pain in last month 8.7 14.9 22.3 1.1 -4.0 3.7 3.8 4.2 4.4 4.4 4.3 -4.5 -0.3 4.7 4.5 4.5 4.3 4.5 1.6 4.4 4.2 4.0 2.1 4.1 1.0 4.2 4.6
Medication for cholesterol, blood pressure or diabetes 2.2 3.7 7.6 1.5 -2.2 2.3 2.4 2.2 2.3 2.6 2.2 -2.8 -0.8 0.8 1.5 1.7 2.2 2.1 -1.8 2.6 1.1 1.2 -0.2 1.7 -1.2 1.4 2.6
Glaucoma (self-reported) 4.8 5.6 12.6 1.6 -3.5 2.8 2.3 3.1 2.5 2.7 3.0 -2.7 -1.0 1.5 2.1 2.0 3.0 3.0 0.9 2.8 1.5 2.3 2.1 1.7 -1.6 2.0 2.8
Gout (self-reported) 2.9 3.9 13.5 -1.4 -2.4 2.4 2.1 2.3 0.4 2.4 2.3 -2.5 -3.7 1.6 1.7 1.9 2.2 2.3 -0.7 1.9 -0.7 2.0 0.5 1.5 -0.3 1.7 2.6
Hypothyroidism/myxoedema (self-reported) 0.4 0.9 7.0 -0.2 0.5 -0.8 -0.9 -0.2 -0.2 -1.4 -0.3 1.1 0.6 -0.4 -0.0 -0.5 -0.5 -0.2 2.6 0.0 -1.8 0.4 1.4 0.2 -0.5 0.7 -1.2
Medication: Amlodipine 1.5 2.0 5.3 -1.1 0.9 -0.9 -1.7 -1.0 -2.0 -1.1 -1.2 1.0 -2.3 -0.9 -1.8 -1.6 -1.2 -1.3 -1.7 -1.7 -0.9 -1.3 -1.5 -2.2 1.0 -1.6 -0.8
Medication: Ventolin 100micrograms inhaler 0.5 0.6 2.4 1.5 -0.7 1.2 0.7 0.7 1.2 0.8 0.6 -0.9 1.2 0.5 0.1 0.1 0.5 0.6 0.2 0.8 1.3 0.6 0.1 -0.3 -0.7 0.1 0.6
Birth weight 0.5 1.2 10.8 -3.3 0.8 -0.6 -0.7 -0.9 -0.7 -0.2 -0.5 0.1 -0.5 0.3 0.9 1.4 -0.4 -0.4 -1.4 -0.4 0.6 -0.7 -1.7 1.1 2.1 0.0 -0.1
Chronic bronchitis/emphysema (mother) 0.8 0.9 2.2 -1.5 -1.3 0.3 0.4 1.1 0.7 0.8 1.2 -0.8 -0.2 0.4 1.4 1.4 1.3 1.3 -0.3 1.0 -0.8 0.9 -0.1 1.3 0.3 1.2 0.9
High blood pressure (siblings) 0.3 0.4 3.7 -0.4 0.3 -0.2 -0.3 -0.4 -1.0 -0.0 -0.4 0.3 -0.8 -0.5 -0.2 -0.1 -0.3 -0.4 -1.9 -0.9 -0.6 -0.7 -1.1 -0.8 0.0 -0.5 -0.3
Forced vital capacity (FVC), Best measure 0.6 2.1 5.2 -2.3 -1.0 1.9 1.9 0.9 0.6 1.7 1.2 -1.3 -2.3 1.2 1.8 2.2 1.5 1.2 -1.6 1.0 0.8 0.5 -0.7 1.8 1.0 1.1 1.3
Body fat percentage 0.2 0.7 6.0 -0.3 -0.5 -0.9 -0.7 0.7 0.5 0.2 0.6 -0.8 0.9 0.9 0.7 0.5 0.3 0.6 2.4 0.4 1.0 1.4 0.3 0.1 0.8 0.8 0.8
Leg fat percentage (right) 0.4 1.3 5.4 1.0 0.6 -2.1 -2.2 -0.3 -0.7 -1.2 -0.6 0.4 1.8 -0.9 -1.0 -1.3 -1.1 -0.7 2.3 -0.4 0.3 0.2 -0.2 -1.9 -0.4 -0.7 -0.5
Arm fat-free mass (right) 1.4 7.4 25.6 -5.1 3.3 -4.3 -4.2 -3.3 -4.0 -3.1 -2.8 2.4 2.1 -1.6 0.1 0.4 -3.2 -2.7 -0.5 -1.9 -0.5 -1.8 -2.5 -1.0 2.2 -1.5 -2.8
Exposure to tobacco smoke outside home 1.0 1.3 3.4 -0.3 -1.2 0.1 -0.4 1.5 0.7 0.6 1.5 -1.2 -0.2 0.8 1.8 1.6 1.0 1.6 1.3 1.6 0.6 1.7 0.9 1.1 0.9 1.4 1.3
Comparative body size at age 10 3.0 8.3 21.3 0.3 3.3 -3.2 -3.1 -2.9 -2.3 -2.8 -3.0 2.6 3.9 -3.0 -2.4 -2.2 -3.2 -2.9 -1.8 -2.6 -0.4 -3.4 -4.6 -3.3 -1.3 -3.5 -2.9
Number of full brothers 1.7 2.2 3.9 0.9 1.8 -1.8 -1.9 -1.8 -1.3 -1.6 -1.8 1.7 1.9 -0.8 -1.5 -1.6 -2.0 -1.8 -0.4 -1.5 0.2 -1.6 0.1 -1.4 0.7 -1.4 -1.4
Worry too long after embarrassment 1.1 1.8 4.6 0.2 -0.8 2.0 1.8 1.4 1.0 2.1 1.3 -1.9 -1.5 1.2 0.3 0.8 1.2 1.2 -2.0 0.8 1.9 -0.1 -1.7 0.3 -0.7 -0.1 1.7
Seen a psychiatrist for nerves, anxiety, tension or depression 4.6 6.0 9.7 -1.2 -2.9 2.5 1.8 3.0 2.6 3.0 3.1 -3.1 -1.1 2.9 2.9 3.1 2.9 3.1 -0.4 2.7 1.8 2.2 -0.3 2.3 0.3 2.1 3.1
Wheeze or whistling in the chest in last year 2.5 4.5 8.1 -0.7 -2.4 1.4 1.3 2.4 1.6 2.6 2.6 -2.7 -0.7 2.5 2.7 2.8 2.2 2.6 0.0 2.6 1.3 2.3 1.1 2.5 0.4 2.4 2.8
Number of children fathered 0.8 0.9 5.1 1.9 0.3 -1.3 -1.7 -0.4 0.4 -0.6 -0.4 0.1 2.3 0.1 -0.0 -0.1 -0.6 -0.4 2.0 0.5 1.3 -0.1 0.3 -0.6 -0.4 -0.4 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.1 2.9 -0.9 -0.7 0.8 1.6 0.7 0.6 1.0 0.9 -0.6 -1.1 1.5 1.1 1.1 1.2 1.0 1.0 -0.1 1.4 1.1 1.0 1.7 0.3 1.3 0.6
Age at first live birth 0.8 1.4 3.3 -1.5 1.5 -0.6 -0.5 -1.5 -0.9 -1.6 -1.4 1.7 -0.6 -0.8 -1.0 -1.1 -1.2 -1.4 1.0 -1.6 -1.2 -1.3 -0.8 -0.3 0.1 -1.0 -1.8
Pulse wave peak to peak time 1.2 1.4 3.5 -0.1 -0.7 1.0 1.3 0.9 1.0 1.0 1.1 -0.6 0.4 1.4 1.6 1.5 1.1 1.2 1.2 1.7 0.9 1.2 1.6 1.9 0.4 1.5 0.7
Health satisfaction 0.1 0.1 1.2 -0.5 -0.3 -0.1 -0.0 0.3 -0.4 0.5 0.2 -0.3 -0.2 -0.4 -0.0 0.2 0.2 0.1 -1.1 0.4 0.2 -0.0 -0.5 -0.5 -0.3 -0.3 0.2
Shortness of breath walking on level ground 0.8 0.9 2.5 0.2 -0.7 -0.9 -1.1 0.8 -0.2 0.8 0.8 -1.4 0.3 0.0 1.4 1.5 0.4 0.8 -1.3 1.5 0.4 1.3 0.7 0.3 1.0 0.8 1.6
Qualifications: College or University degree 0.5 1.5 5.2 -0.5 -0.8 1.9 2.3 0.7 2.2 1.4 1.0 -0.4 0.1 1.4 1.0 1.3 1.2 1.0 -1.0 0.2 0.7 0.1 -1.5 1.5 -1.7 0.7 0.1
Eye problems/disorders: None of the above 2.9 3.4 8.5 1.3 1.9 -1.0 -0.6 -2.2 -1.3 -1.4 -2.3 1.9 0.3 -2.2 -2.9 -2.7 -2.0 -2.5 -1.5 -2.1 -1.3 -2.0 -1.1 -2.1 0.3 -2.1 -1.9
Mouth/teeth dental problems: Loose teeth 0.7 0.9 1.6 0.1 -0.9 1.0 1.1 0.9 0.7 1.1 1.0 -0.8 -0.4 1.0 1.0 1.0 1.2 1.0 0.1 1.3 0.5 1.2 1.3 1.1 0.5 1.2 0.8
Emphysema/chronic bronchitis 0.5 0.6 3.5 -1.2 -0.1 0.5 0.5 0.2 -0.4 0.1 0.2 0.1 -1.9 -0.4 -0.1 -0.2 0.4 0.3 -1.6 0.5 -1.6 0.3 0.9 0.6 1.0 0.3 0.1
Medication for pain relief, constipation, heartburn 1.8 3.2 9.3 0.0 2.1 -1.4 -1.0 -2.1 -1.6 -2.4 -2.1 2.3 0.9 -1.7 -2.1 -2.5 -1.9 -2.1 0.5 -1.5 -3.1 -1.7 0.4 -0.9 -0.2 -1.5 -2.3
Neck or shoulder pain in last month 1.0 1.4 3.8 0.9 -1.6 0.7 1.0 1.7 1.1 1.3 1.5 -1.7 -2.0 -0.1 0.6 0.7 1.4 1.4 0.3 1.2 0.9 0.8 -0.9 0.2 -1.6 0.7 1.4
Medication: Blood pressure 2.9 5.1 10.2 -2.6 2.6 -2.6 -2.6 -2.5 -2.8 -3.0 -2.4 3.2 0.4 -1.1 -1.5 -1.8 -2.4 -2.4 1.9 -3.2 -2.1 -1.5 -0.8 -1.7 1.2 -1.5 -3.0
Angina (self-reported) 0.5 0.7 1.4 -0.2 0.8 -0.6 -0.8 -0.9 -0.8 -0.9 -0.9 1.2 1.1 -0.6 -0.6 -0.7 -0.9 -0.9 0.8 -0.9 -0.8 -1.1 -0.5 -0.9 -0.0 -0.8 -1.0
Migraine (self-reported) 2.6 3.2 6.0 -0.3 -1.6 2.1 2.5 1.8 2.0 1.7 1.9 -1.8 -1.0 1.8 2.0 1.9 2.1 2.0 1.6 2.1 -0.7 2.1 1.2 2.5 0.4 2.3 1.5
Medication: Ibuprofen 1.1 1.3 2.4 -0.4 1.5 -1.3 -1.2 -1.6 -1.4 -1.1 -1.4 1.4 0.6 -0.3 -0.7 -0.5 -1.5 -1.4 0.7 -1.6 1.4 -0.8 -0.6 -1.0 0.9 -1.0 -1.3
Medication: Allopurinol 1.8 2.4 4.5 -0.6 -2.1 1.8 1.6 2.1 0.3 1.8 2.0 -2.0 -2.1 1.0 1.5 1.5 1.9 2.0 -0.4 1.7 -0.4 1.8 1.0 1.2 -0.8 1.4 2.1
Medication: Omeprazole 0.6 0.7 5.8 0.8 -0.7 0.1 -0.3 0.4 -0.1 0.7 0.4 -0.5 0.2 -0.7 -0.2 0.2 0.2 0.3 -1.5 0.8 0.7 -0.6 -1.5 -0.8 -2.4 -0.8 0.3
Medication: Seretide 50 evohaler 0.8 0.9 2.3 -0.9 1.2 -0.7 -0.7 -1.0 -1.3 -0.6 -1.0 0.5 -1.3 -0.6 -1.0 -0.9 -1.1 -1.0 -0.4 -1.5 -0.8 -1.0 -1.4 -0.9 -0.0 -1.2 -0.7
Mean time to correctly identify matches 0.3 0.6 4.5 -0.7 -0.2 -0.9 -1.2 0.2 0.3 -0.4 0.1 -0.1 -1.1 -0.0 0.4 0.2 0.1 0.2 1.4 -1.2 -0.9 0.8 0.3 0.1 2.1 0.8 0.3
Heart disease (mother) 0.2 0.2 2.1 0.2 -0.5 -0.2 -0.8 0.6 0.1 -0.2 0.4 -0.2 -0.2 0.2 -0.1 -0.1 0.2 0.3 0.7 0.4 1.4 0.7 0.8 -0.2 0.2 0.3 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 2.3 0.3 1.3 -1.1 -1.1 -1.1 -0.7 -1.0 -1.2 1.1 0.0 -0.9 -1.4 -1.5 -1.3 -1.3 -0.5 -1.4 -1.0 -0.9 -0.1 -1.3 0.4 -1.4 -0.8
Whole body fat mass 0.3 1.1 4.7 -2.0 0.6 -2.2 -1.9 -0.5 -0.9 -0.9 -0.4 0.2 1.5 0.3 0.6 0.6 -0.7 -0.3 2.0 -0.3 0.7 0.5 -0.7 -0.2 1.3 0.2 -0.3
Leg fat mass (right) 0.7 2.6 10.8 -1.4 1.6 -3.3 -3.3 -1.4 -2.0 -2.0 -1.5 1.1 2.2 -0.9 -0.6 -0.6 -1.9 -1.4 1.9 -1.0 0.3 -0.4 -1.2 -1.6 0.8 -1.0 -1.3
Arm predicted mass (right) 1.5 7.6 26.2 -5.1 3.4 -4.2 -4.2 -3.4 -4.0 -3.2 -2.9 2.6 2.0 -1.7 -0.1 0.2 -3.2 -2.8 -0.5 -2.1 -0.7 -2.0 -2.4 -1.1 2.2 -1.6 -3.0
Pulse rate, automated reading 3.7 11.9 27.8 4.3 -4.2 5.3 5.2 4.2 4.8 4.8 3.9 -4.1 -1.1 1.6 0.8 1.0 4.0 3.6 -2.3 3.9 1.2 2.1 -0.0 1.5 -4.4 1.6 3.9
Alcohol intake frequency. 0.8 1.8 4.5 1.3 -1.7 1.5 1.3 1.6 1.3 1.9 1.5 -2.0 -0.4 0.7 0.9 1.0 1.5 1.5 -0.3 2.1 0.4 1.1 0.8 0.8 -0.6 1.0 2.0
Comparative height size at age 10 1.9 10.6 26.9 -2.3 -2.5 2.4 3.1 2.5 3.2 3.7 3.2 -3.5 0.3 3.7 4.6 5.2 3.4 3.4 -1.2 3.2 4.7 2.2 0.2 5.0 1.8 3.1 3.5
Number of full sisters 0.7 0.9 2.0 -0.0 1.2 -1.2 -1.2 -1.3 -0.7 -0.8 -1.2 0.4 0.9 -0.4 -0.6 -0.5 -1.2 -1.1 -0.7 -0.9 -0.7 -1.3 -1.3 -0.8 1.4 -0.8 -0.3
Suffer from ‘nerves’ 4.7 7.4 15.5 -3.3 -2.5 2.6 2.2 2.6 1.8 2.8 3.0 -2.9 -2.7 3.2 3.7 3.9 2.7 3.1 -0.1 2.1 0.7 3.0 0.7 3.7 1.9 3.0 2.9
Overall health rating 1.0 2.1 6.3 0.4 -2.1 1.3 1.1 2.1 1.2 2.0 2.0 -2.0 -0.1 0.7 1.2 1.3 1.8 1.9 -0.1 2.5 1.1 0.9 0.2 0.7 -0.7 0.7 2.1
Chest pain or discomfort 2.9 4.1 6.6 -1.1 -2.2 2.6 2.4 2.5 2.1 2.3 2.5 -2.4 -1.6 1.4 2.2 2.2 2.6 2.6 -0.9 2.0 -0.0 2.2 0.5 2.3 0.0 2.2 2.3
Had major operations 0.6 0.7 3.8 0.3 0.3 -0.2 -0.1 -0.0 -0.2 -0.6 -0.2 0.5 -0.7 -2.0 -0.8 -0.9 -0.3 -0.3 -0.8 -1.4 -1.8 -0.5 -1.0 -0.8 -1.5 -0.5 -0.7
Age at last live birth 0.4 0.5 1.7 -1.2 0.7 -0.3 -0.2 -0.9 -0.6 -0.8 -0.8 1.1 -0.2 -0.8 -0.5 -0.5 -0.4 -0.7 0.5 -0.8 -1.3 -0.9 -0.5 -0.1 -0.2 -0.5 -1.1
Family relationship satisfaction 3.6 4.4 13.2 -0.1 -1.9 3.0 3.6 2.0 2.3 2.9 2.3 -1.9 -0.7 2.2 2.0 2.2 2.4 2.2 -1.5 2.1 1.3 1.9 1.4 2.8 0.0 1.9 1.9
Leg pain on walking 0.2 0.3 1.1 0.8 -0.3 -0.7 -0.8 0.5 -0.3 0.1 0.2 -0.5 -0.3 -0.6 -0.4 -0.5 0.0 0.2 -1.1 0.5 -1.0 0.0 -0.0 -0.9 -0.6 -0.3 0.7
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.5 3.7 1.9 -1.4 1.8 1.7 1.4 1.9 1.3 1.3 -1.1 -0.4 0.8 0.3 -0.0 1.4 1.2 0.7 1.0 0.2 1.0 1.2 0.5 -1.6 1.0 1.1
Commuting to job workplace: Car/motor vehicle 0.2 0.2 1.2 0.2 0.2 -0.5 -0.8 -0.1 0.0 -0.4 -0.0 0.1 0.1 -0.0 0.6 0.5 -0.2 0.0 0.8 0.6 0.5 0.9 0.6 0.4 1.1 0.6 -0.1
Illness, injury, bereavement, stress in last 2 years 4.1 5.0 11.2 -1.6 2.8 -2.3 -2.2 -2.9 -3.3 -2.7 -2.8 2.7 -0.1 -2.1 -1.9 -2.0 -2.5 -2.7 -0.8 -2.3 -1.9 -1.9 -0.2 -1.6 2.2 -2.0 -2.5
Medication: Aspirin 0.6 0.7 3.5 0.5 -0.7 0.3 -0.2 0.9 0.8 0.6 0.7 -0.6 -1.9 0.9 -0.1 -0.0 0.5 0.6 1.0 -0.3 1.3 1.5 1.5 -0.2 0.9 0.9 0.7
Supplements: Vitamin C 0.1 0.1 1.3 0.2 -0.4 0.4 0.2 0.3 0.3 0.4 0.2 -0.3 -1.1 0.1 -0.1 -0.0 0.1 0.1 -0.6 0.1 0.3 0.2 0.2 -0.3 0.5 -0.1 0.5
Knee pain experienced in last month 0.5 0.8 3.4 1.9 -1.1 -0.4 -0.3 1.3 0.7 0.4 1.0 -1.0 -0.3 -0.2 -0.1 -0.3 0.6 0.9 0.6 0.6 1.7 0.9 0.4 -0.7 -0.8 0.2 1.1
Hypertension (Self-reported) 1.4 3.8 9.6 -1.7 1.6 -2.1 -2.4 -1.7 -2.4 -2.3 -2.0 2.1 -2.0 -1.9 -2.0 -2.1 -1.8 -2.0 1.4 -3.1 -1.5 -0.9 -0.9 -2.5 1.4 -1.5 -2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.7 0.8 2.8 -0.9 1.0 0.3 0.7 -1.3 -0.6 -0.3 -1.1 1.0 0.4 -0.2 -0.9 -0.6 -0.6 -1.1 -1.1 -0.9 -0.5 -1.2 -1.7 -0.4 -0.1 -1.2 -1.2
Illnesses of father: Heart disease 0.2 0.3 2.8 0.6 -0.2 0.1 -0.6 0.5 0.7 -0.3 0.2 0.2 -0.9 -0.3 -0.7 -0.8 -0.0 0.1 1.7 -0.1 -0.6 0.2 0.3 -1.0 0.4 -0.3 0.1
Illnesses of siblings: Diabetes 2.1 2.6 5.6 -0.6 1.6 -1.2 -0.9 -1.8 -1.4 -1.4 -1.8 1.7 0.1 -1.6 -1.7 -1.7 -1.5 -1.8 -1.9 -2.2 -2.4 -2.1 -1.6 -1.4 -1.1 -1.8 -1.7
Smoking status: Previous 1.1 1.7 5.2 1.6 1.2 -2.3 -2.2 -1.1 -1.6 -1.2 -1.3 1.0 1.9 -1.7 -0.8 -1.0 -1.5 -1.2 -0.2 -0.4 0.4 -0.8 -0.2 -1.7 -0.8 -1.1 -1.0
Forced expiratory volume in 1-second (FEV1), predicted 1.6 3.4 9.5 -1.5 -1.1 1.8 2.2 1.2 1.4 1.9 1.6 -1.8 -0.6 2.0 2.8 3.0 1.9 1.8 -0.7 2.0 1.6 1.6 0.3 3.1 1.6 2.0 1.6
Whole body fat-free mass 1.5 8.5 32.3 -5.7 3.6 -4.4 -4.3 -3.6 -4.2 -3.3 -3.1 2.7 2.4 -1.6 0.1 0.5 -3.3 -2.9 -0.7 -2.2 -0.4 -2.1 -2.6 -0.9 2.5 -1.7 -3.0
Leg fat-free mass (right) 1.5 7.8 32.8 -5.7 3.4 -4.3 -4.2 -3.4 -4.0 -3.1 -2.9 2.3 2.3 -1.1 0.1 0.5 -3.2 -2.7 -0.0 -2.3 -0.3 -1.7 -2.6 -0.7 2.7 -1.4 -2.7
Arm fat percentage (left) 0.4 1.4 6.1 -1.3 1.1 -2.3 -2.1 -0.8 -1.4 -1.3 -0.9 0.6 1.6 -0.4 -0.4 -0.5 -1.3 -0.9 2.5 -1.2 -0.2 0.2 -0.6 -1.0 0.9 -0.4 -0.7
Average weekly red wine intake 0.8 1.1 8.2 1.5 0.4 -0.5 -0.6 -0.3 0.7 -0.5 -0.2 0.2 2.9 1.3 0.8 0.7 -0.4 -0.1 2.0 0.3 2.3 0.8 0.8 0.2 0.5 0.5 -0.6
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.5 -0.6 0.2 -0.4 -0.6 -0.2 0.2 0.1 -0.1 0.1 0.3 0.1 0.5 0.7 -0.2 -0.0 -0.6 0.4 0.4 -0.0 -0.3 0.1 0.4 -0.0 -0.1
Mood swings 1.8 3.2 11.6 -3.1 -1.1 0.1 0.2 1.4 0.7 1.1 1.8 -1.4 0.1 2.1 3.3 3.4 1.2 1.9 1.6 1.6 0.4 2.1 0.2 2.6 1.5 2.1 1.3
Loneliness, isolation 0.8 1.1 5.9 -2.4 -0.4 -0.7 -0.3 0.4 -0.1 0.2 0.7 -0.4 0.6 1.1 2.0 2.0 0.4 0.8 0.6 1.0 0.2 0.8 0.0 1.7 1.2 1.3 0.5
Long-standing illness, disability or infirmity 0.6 1.0 4.7 1.1 0.2 -0.6 -0.4 0.1 -0.4 0.3 -0.1 -0.4 0.5 -0.8 -0.6 -0.6 -0.4 -0.2 -1.5 -0.3 1.0 -1.2 -2.2 -1.7 -2.1 -1.4 0.4
Ever had bowel cancer screening 0.3 0.3 2.4 0.1 0.0 0.3 0.5 -0.2 -0.2 0.3 -0.2 0.4 -1.5 -0.0 -0.6 -0.4 0.2 -0.2 -0.7 -0.5 1.4 -0.3 0.5 -0.3 0.4 -0.5 -0.1
Diabetes diagnosed by doctor 1.8 2.9 7.3 0.9 1.3 -2.1 -1.9 -1.4 -1.8 -1.9 -1.7 1.6 0.4 -2.2 -2.2 -2.3 -1.8 -1.8 -0.8 -1.9 -1.4 -1.3 -0.7 -2.7 -0.8 -2.0 -1.6
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.3 1.3 0.8 -0.4 -0.1 0.2 0.6 0.2 0.6 0.4 -1.1 -0.4 -0.1 0.0 0.1 0.3 0.4 0.3 0.3 1.1 0.2 -0.2 -0.5 -0.2 0.0 0.9
Friendships satisfaction 2.2 2.7 7.1 -1.7 -0.9 1.9 2.1 1.2 1.8 1.5 1.5 -1.2 -0.4 2.1 2.2 2.3 1.6 1.6 0.3 1.3 0.0 1.9 1.2 2.7 1.9 2.1 0.9
Qualifications: nursing, teaching 0.7 1.0 3.7 0.2 0.9 -0.4 -0.3 -1.0 0.5 -0.9 -0.9 1.3 1.9 -0.2 -0.8 -0.6 -0.9 -1.0 1.2 -1.6 1.1 -1.1 -1.5 -0.7 -0.6 -1.0 -1.4
Commuting to job workplace: Walk 0.9 1.0 5.4 2.3 -0.9 1.2 1.2 1.0 0.6 0.9 0.7 -1.2 -0.9 -0.5 -0.6 -0.7 0.8 0.6 -1.4 0.6 -0.6 -0.3 -0.6 -0.6 -1.9 -0.2 1.2
Eye problems/disorders: Cataract 2.5 2.9 7.6 -1.6 -1.5 1.0 0.7 1.9 1.9 1.0 2.0 -1.2 0.6 2.2 2.8 2.5 1.7 2.2 2.2 1.8 0.7 1.5 0.4 2.2 -0.3 2.2 1.3
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 3.2 -0.7 0.9 -1.3 -0.6 -1.0 -1.3 -0.2 -1.0 -0.1 -0.7 -0.8 -0.9 -0.6 -1.0 -1.1 -1.8 -0.4 -1.2 -0.9 -1.8 -0.5 0.9 -0.8 -0.0
Medication for cholesterol 1.4 2.2 8.4 -2.5 0.1 0.1 0.4 -0.4 -0.3 -0.1 0.1 0.4 0.3 2.3 1.9 1.9 0.2 0.3 2.8 0.4 -0.5 1.1 2.1 2.6 2.9 2.0 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.2 3.8 11.3 -1.0 -1.8 0.2 0.1 2.0 1.2 1.5 2.2 -1.9 -0.6 1.8 3.4 3.3 1.7 2.4 2.4 1.6 1.2 2.5 1.3 2.4 0.8 2.8 2.1
Back pain experienced in last month 2.9 4.3 8.1 -0.8 1.9 -2.3 -2.1 -2.1 -2.6 -1.9 -2.2 1.8 0.6 -2.9 -2.0 -1.9 -2.0 -2.2 -2.0 -1.7 -1.0 -2.7 -2.9 -2.4 -0.8 -2.6 -1.9
Mineral and other dietary supplements 2.1 2.8 5.8 -1.1 -1.5 2.4 2.2 1.7 1.9 1.5 1.8 -1.1 -1.9 2.1 1.3 1.1 2.0 1.8 0.7 1.3 -0.8 1.9 1.8 2.1 1.4 1.9 1.3
Breast cancer (self-reported) 0.4 0.5 1.8 0.7 -0.8 1.0 0.8 0.6 1.3 0.7 0.5 -0.9 -1.3 0.5 -0.1 -0.0 0.6 0.5 -0.6 0.2 0.9 0.5 -0.0 -0.2 0.4 0.1 0.9
Asthma (self-reported) 0.1 0.2 0.8 0.2 -0.2 -0.1 -0.2 0.3 0.1 0.5 0.4 -0.6 0.9 0.1 0.5 0.4 0.1 0.4 -0.4 0.2 0.2 0.3 -0.1 0.3 -0.9 0.1 0.5
Osteoporosis (self-reported) 0.1 0.1 0.8 0.0 0.2 0.6 0.4 -0.1 0.3 -0.2 -0.2 0.2 0.4 -0.1 -0.2 -0.3 -0.2 -0.1 -0.1 -0.3 -0.9 -0.8 -0.6 -0.3 -0.2 -0.4 0.0
Osteoarthritis (self-reported) 1.4 1.9 4.2 1.3 -2.0 0.0 -0.5 2.0 1.3 0.9 1.7 -1.6 0.3 0.5 1.0 1.0 1.3 1.6 2.0 1.7 1.9 1.9 0.9 0.0 -1.2 1.4 1.3
Medication: Aspirin 0.9 1.1 4.8 0.6 -1.0 0.5 -0.1 1.2 1.1 0.8 1.0 -0.9 -2.2 1.3 0.3 0.3 0.7 0.9 1.2 -0.1 1.3 1.8 1.6 0.0 1.1 1.2 1.1
Medication: Gliclazide 0.3 0.3 1.5 1.2 -0.8 0.1 0.3 0.7 0.7 0.7 0.5 -0.5 -0.4 0.4 -0.5 -0.5 0.6 0.4 0.1 0.2 0.9 0.6 1.1 -0.2 -0.1 0.3 0.6
Illnesses of father: None of the above (group 1) 0.5 0.7 4.2 1.2 -0.3 0.8 1.1 0.2 0.4 1.1 0.3 -1.0 0.2 0.4 -0.0 0.2 0.2 0.3 -1.8 0.6 2.1 0.1 -0.0 0.3 -1.0 0.1 0.9
Smoking status: Current 1.4 2.2 4.7 1.7 1.4 -1.6 -1.6 -1.3 -1.0 -1.2 -1.4 1.0 1.8 -1.9 -1.7 -1.7 -1.6 -1.5 -1.0 -1.1 -1.0 -1.9 -1.3 -2.2 -1.0 -1.8 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 2.7 0.2 -0.0 0.4 0.1 0.1 0.1 -0.4 -0.1 1.0 -0.8 -1.1 -0.9 -1.1 -0.0 -0.2 -0.5 -0.6 -0.8 -0.8 -0.0 -0.9 -1.6 -0.9 -0.7
Whole body water mass 1.6 9.0 32.4 -5.7 3.7 -4.5 -4.4 -3.7 -4.3 -3.3 -3.2 2.8 2.4 -1.6 0.0 0.4 -3.5 -3.0 -0.7 -2.4 -0.2 -2.2 -2.7 -1.0 2.5 -1.8 -3.1
Leg predicted mass (right) 1.5 7.8 31.4 -5.6 3.4 -4.3 -4.2 -3.4 -4.0 -3.1 -2.9 2.3 2.3 -1.2 0.1 0.4 -3.2 -2.7 -0.1 -2.3 -0.2 -1.8 -2.6 -0.8 2.6 -1.5 -2.7
Arm fat mass (left) 0.8 3.2 11.3 -2.6 1.9 -3.4 -3.2 -1.7 -2.4 -2.1 -1.7 1.2 2.0 -0.8 -0.4 -0.4 -2.1 -1.6 1.8 -1.6 -0.2 -0.5 -1.4 -1.4 1.4 -1.0 -1.5
Number of self-reported non-cancer illnesses 0.0 0.1 0.3 -0.3 -0.0 0.6 0.2 0.2 -0.0 0.2 0.2 0.1 -0.2 0.3 0.1 0.1 0.2 0.2 0.6 0.1 0.4 0.1 -0.2 -0.4 -0.2 -0.2 -0.1
Average weekly champagne plus white wine intake 4.0 5.4 10.4 -1.0 2.8 -2.4 -2.5 -2.7 -2.8 -2.9 -2.8 3.1 0.3 -2.1 -2.5 -2.6 -2.9 -2.8 -0.6 -3.2 -1.2 -2.3 -0.3 -2.1 1.1 -2.0 -2.8
Miserableness 0.7 1.2 6.3 -2.5 1.0 -1.5 -2.1 -0.9 -2.0 -1.2 -0.8 0.7 -0.4 -0.5 0.5 0.6 -1.3 -0.7 0.1 -0.5 -1.0 -0.3 -1.1 -0.2 1.3 -0.4 -0.7
Guilty feelings 4.3 6.4 10.8 -0.4 -2.7 2.5 2.0 3.0 2.4 2.8 3.2 -3.0 -1.2 2.0 3.3 3.3 2.8 3.2 0.1 3.2 0.7 2.8 1.4 3.0 1.0 3.0 3.0
Wears glasses or contact lenses 5.9 6.8 15.1 -2.1 3.0 -3.2 -3.7 -3.2 -2.4 -3.9 -3.1 3.7 0.0 -2.0 -1.8 -2.1 -3.3 -3.0 1.2 -3.3 -2.2 -1.8 -0.2 -1.8 1.4 -1.8 -3.5
Ever taken oral contraceptive pill 0.5 0.6 3.3 -0.4 0.5 -1.7 -1.8 -0.7 -0.9 -0.6 -0.6 0.3 0.3 -0.0 -0.3 -0.1 -0.8 -0.6 -0.5 -0.7 0.9 -0.5 -1.0 -0.7 -0.1 -0.7 -0.3
Hearing aid user 1.9 2.1 4.8 0.4 1.5 -2.0 -2.1 -1.5 -1.9 -1.7 -1.7 1.0 0.6 -1.5 -1.5 -1.6 -1.7 -1.6 0.0 -1.1 -0.8 -1.5 -1.1 -2.2 0.1 -1.8 -1.2
Mother’s age at death 0.4 0.5 2.1 -0.3 -0.1 0.3 0.6 0.4 0.4 -0.2 0.4 0.0 -1.4 0.4 0.7 0.5 0.5 0.5 0.3 0.4 -1.3 0.9 0.7 1.3 0.9 0.9 0.0
Financial situation satisfaction 0.2 0.2 0.5 -0.1 -0.5 -0.4 0.2 0.7 -0.2 0.7 0.6 -0.7 -0.2 -0.5 0.5 0.7 0.6 0.7 -0.5 0.4 0.5 0.3 0.2 0.2 0.1 0.4 0.7
Tinnitus: Yes, now most or all of the time 2.4 2.9 6.2 -0.2 -2.1 2.1 1.9 1.8 1.5 2.0 1.9 -1.9 -2.5 1.6 1.3 1.4 2.1 1.9 1.2 1.2 0.1 2.2 1.2 1.9 -0.0 2.0 1.8
Commuting to job workplace: Public transport 0.5 0.7 3.9 0.6 -0.8 0.4 0.5 0.8 1.0 0.7 0.8 -0.6 2.0 0.9 0.7 0.7 0.7 0.8 -0.5 1.1 1.1 0.2 0.3 0.5 -0.8 0.3 0.7
Eye problems/disorders: Glaucoma 1.9 2.3 4.7 0.7 -2.2 2.1 1.8 1.9 1.2 1.7 1.9 -1.6 -1.5 0.4 1.2 1.1 2.0 1.9 -0.1 1.6 0.0 1.4 1.4 1.2 -1.3 1.2 1.8
Medication: Blood pressure 1.2 2.4 6.9 -0.5 1.0 -1.0 -1.5 -1.0 -1.3 -1.2 -1.3 0.8 -1.8 -2.3 -1.9 -1.8 -1.1 -1.3 -1.4 -2.1 -0.8 -1.3 -2.6 -2.6 -0.2 -1.9 -1.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 3.6 1.8 -1.2 0.6 0.7 1.1 1.0 1.2 0.9 -1.3 -0.2 0.2 -0.3 -0.1 0.7 0.7 0.4 0.8 1.9 0.6 -0.8 -0.8 -1.2 -0.2 1.2
Supplements: Fish oil (including cod liver oil) 1.7 2.2 5.5 0.3 1.5 -2.3 -2.0 -1.6 -1.9 -1.5 -1.7 1.4 1.3 -1.7 -1.1 -1.0 -1.8 -1.7 0.1 -1.5 0.7 -1.6 -1.2 -1.9 -0.7 -1.7 -1.4
High cholesterol (Self-reported) 1.0 1.8 5.9 -1.1 1.2 -1.8 -2.1 -1.2 -2.4 -1.5 -1.4 1.2 -1.4 -1.5 -1.3 -1.4 -1.3 -1.4 0.1 -1.5 -0.5 -0.4 0.2 -1.6 0.4 -1.1 -1.4
Medication: Bendroflumethiazide 2.2 3.3 7.0 -0.6 1.8 -1.9 -2.1 -1.9 -2.0 -1.7 -2.1 1.5 -0.6 -1.8 -2.1 -2.0 -1.9 -2.1 -1.5 -2.1 -0.6 -2.0 -1.8 -2.6 1.6 -2.3 -1.4
Medication: Paracetamol 1.1 1.7 3.7 0.5 -1.4 1.4 0.9 1.5 1.0 1.7 1.5 -1.9 -0.7 1.2 1.0 1.3 1.4 1.4 -1.6 1.6 1.7 0.9 -1.1 0.5 -0.6 0.7 1.8
Medication: Lisinopril 0.3 0.4 3.6 0.2 -0.1 -0.4 -0.4 0.0 -0.3 -0.5 -0.2 0.1 -0.9 0.4 -0.8 -0.9 -0.2 -0.2 1.9 -0.4 0.0 0.4 0.2 -1.2 1.1 -0.3 -0.0
Medication: Atorvastatin 1.3 1.6 3.3 -0.2 0.7 -0.4 -0.4 -0.9 -1.4 -1.1 -1.0 1.5 -1.6 -1.7 -1.8 -1.8 -0.7 -1.1 -1.2 -1.8 -1.2 -1.2 -1.1 -1.5 -1.7 -1.3 -1.5
Illnesses of father: High blood pressure 1.6 2.0 12.5 -2.7 1.0 -0.5 -0.9 -0.9 -1.9 -1.7 -0.9 1.5 -2.1 -1.5 -0.3 -0.6 -0.8 -0.8 0.4 -1.6 -3.5 -0.7 -1.1 -0.6 0.3 -0.7 -1.6
Alcohol drinker status: Never 2.2 2.6 5.0 0.1 -1.9 1.6 1.4 2.0 1.3 1.6 1.9 -1.4 -1.1 1.9 1.6 1.5 1.9 2.0 2.2 1.4 1.8 1.8 1.3 1.1 0.9 1.8 1.7
Ever smoked 4.6 8.1 13.7 1.1 3.3 -3.3 -3.3 -3.1 -3.2 -3.3 -3.2 3.1 1.7 -3.7 -2.6 -2.9 -3.5 -3.2 -1.5 -2.6 -2.3 -2.8 -1.6 -3.3 -1.2 -2.9 -3.2
Basal metabolic rate 1.3 7.2 27.4 -5.2 3.3 -4.3 -4.1 -3.2 -3.8 -2.9 -2.7 2.3 2.4 -1.3 0.2 0.6 -3.0 -2.5 -0.3 -1.9 -0.1 -1.7 -2.5 -0.8 2.5 -1.5 -2.6
Leg fat percentage (left) 0.3 1.2 4.8 0.6 0.5 -2.1 -2.2 -0.3 -0.8 -1.2 -0.6 0.3 1.7 -0.8 -0.9 -1.1 -1.0 -0.6 2.1 -0.5 0.1 0.2 -0.5 -1.8 -0.3 -0.6 -0.5
Arm fat-free mass (left) 1.4 7.1 27.2 -5.2 3.2 -4.2 -4.1 -3.1 -3.9 -3.0 -2.7 2.3 2.2 -1.6 0.2 0.5 -3.0 -2.5 -0.5 -2.0 -0.3 -1.9 -2.7 -1.0 1.8 -1.5 -2.8
Number of operations (self-reported) 0.3 0.4 1.3 0.3 -0.4 0.9 1.0 0.7 1.1 0.8 0.6 -0.6 -0.1 -0.2 0.3 0.4 0.5 0.6 -0.7 -1.1 0.9 0.1 -1.1 -0.1 -0.4 0.2 0.5
Average weekly beer plus cider intake 0.2 0.3 3.4 -0.2 0.0 0.3 0.4 0.2 -0.1 -0.2 0.2 -0.3 -1.2 -0.4 0.1 -0.2 0.1 0.3 0.4 -0.3 -1.9 0.7 0.1 0.6 -0.3 0.5 0.2
Irritability 0.9 1.5 5.9 -1.5 1.1 -2.1 -2.4 -1.1 -1.0 -1.4 -0.9 1.0 1.3 0.5 0.7 0.7 -1.3 -0.8 2.1 -0.6 0.4 0.3 -0.2 -0.2 2.4 0.1 -1.0
Risk taking 1.4 2.0 4.2 0.9 -1.7 1.1 0.9 1.9 1.4 2.0 1.9 -1.8 -0.2 1.3 1.3 1.4 1.6 1.7 -0.7 1.4 1.9 1.3 0.7 0.8 -1.8 1.1 1.8
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.1 -1.5 0.7 -0.5 -0.6 -0.5 -0.5 -0.6 -0.4 0.9 -1.4 0.8 0.2 0.2 -0.4 -0.4 1.4 -1.3 0.6 0.6 1.2 0.3 1.1 0.5 -0.9
Fractured/broken bones in last 5 years 1.6 2.1 4.8 -0.3 1.8 -1.1 -0.8 -1.7 -1.3 -1.2 -1.7 1.0 -0.3 -1.5 -1.6 -1.5 -1.6 -1.7 -1.3 -2.0 -0.9 -2.0 -2.2 -1.6 0.3 -1.9 -1.0
Age started oral contraceptive pill 0.4 0.5 2.7 -1.6 0.1 -0.6 -0.8 -0.4 -0.3 -1.1 -0.2 1.1 0.8 -0.3 0.7 0.6 -0.2 -0.1 0.3 -0.4 -0.7 -0.1 -0.5 0.4 -1.0 0.2 -1.1
Diastolic blood pressure, automated reading 0.9 2.8 7.7 -0.4 -2.0 2.2 2.1 2.3 1.0 2.4 2.1 -2.8 -1.5 1.2 1.2 1.3 2.1 2.0 -0.7 1.5 0.3 1.5 -0.9 0.6 -0.3 0.8 2.6
Ever depressed for a whole week 0.2 0.3 1.7 0.8 -0.2 0.2 -0.0 0.4 1.3 0.5 0.3 -0.6 0.8 -0.1 -0.1 0.0 0.1 0.2 -0.3 0.1 0.3 0.1 -1.0 -0.4 -1.1 -0.2 0.3
Unable to work because of sickness or disability 0.6 0.8 3.5 0.1 0.2 0.9 0.9 -0.1 -0.3 0.4 -0.2 -0.2 -1.2 -0.8 -0.8 -0.9 -0.1 -0.2 -1.6 -0.9 -1.4 -1.0 -1.9 -0.8 -1.1 -1.1 0.3
Commuting to job workplace: Cycle 2.0 2.4 5.7 -1.1 1.5 -1.4 -1.6 -1.5 -1.8 -2.0 -1.6 2.1 -1.0 -1.8 -1.5 -1.8 -1.5 -1.6 1.1 -1.9 -2.4 -1.2 0.8 -1.0 0.1 -1.2 -1.9
Myopia 4.9 7.1 13.2 0.2 3.0 -2.5 -2.4 -3.3 -1.9 -2.7 -3.3 3.1 1.4 -2.7 -3.0 -2.9 -3.2 -3.3 -1.6 -3.6 -1.3 -3.3 -2.2 -2.8 -0.4 -3.2 -3.0
Vascular/heart problems diagnosed by doctor 0.8 2.1 5.8 1.2 -1.1 1.7 2.0 1.1 1.5 1.9 1.4 -1.6 1.0 1.1 1.3 1.4 1.2 1.3 -2.1 2.4 0.8 0.5 0.5 1.9 -1.2 0.9 1.6
Cholesterol lowering medication 0.3 0.4 2.3 -0.1 0.0 -0.1 0.0 0.1 -0.6 -0.1 -0.0 -0.1 -1.0 -1.3 -0.5 -0.5 -0.1 -0.1 -1.2 -0.5 0.0 -0.0 -0.9 -0.8 -1.5 -0.6 -0.2
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 6.2 0.1 -0.8 0.5 0.0 0.5 -0.1 0.7 0.4 -0.5 -0.7 -0.7 -0.2 0.2 0.4 0.3 -1.6 0.5 0.5 -0.5 -1.9 -0.8 -2.5 -0.7 0.2
Pain experienced in last month 0.3 0.4 4.7 0.4 0.1 0.8 0.5 -0.1 0.6 -0.3 -0.1 0.6 -0.2 0.6 -0.1 -0.4 0.0 -0.1 0.8 -0.4 -0.9 0.5 2.2 0.5 0.9 0.6 -0.3
Supplements: Calcium 0.2 0.2 1.1 -0.5 -0.1 -0.3 -0.2 0.2 0.3 0.2 0.2 -0.3 -0.5 0.0 0.5 0.7 0.1 0.3 -1.1 0.1 0.7 -0.1 -1.0 -0.0 0.5 0.2 0.3
Basal cell carcinoma (self-reported) 4.2 4.9 7.8 0.7 -2.8 2.7 2.4 2.7 2.7 2.8 2.8 -2.5 -0.6 2.4 2.1 2.2 2.7 2.7 -0.3 2.8 1.8 1.9 0.4 2.0 -1.9 1.7 2.4
Heart attack/myocardial infarction (self-reported) 0.6 0.8 4.8 0.7 0.3 -1.0 -1.2 -0.3 0.2 -1.1 -0.4 1.2 1.1 -0.1 -0.9 -1.3 -0.5 -0.5 2.2 -0.4 0.0 -0.6 1.3 -0.9 0.0 -0.6 -0.7
Deep venous thrombosis (DVT) (self-reported) 1.9 2.4 5.2 -0.1 -1.9 0.8 1.6 1.8 1.1 1.9 1.9 -1.8 -0.8 1.4 2.3 2.2 2.0 2.1 0.2 1.2 0.7 1.5 0.6 1.8 -1.1 1.7 1.9
Heart disease (siblings) 0.4 0.5 1.8 0.2 -0.8 0.1 -0.5 0.7 0.5 0.5 0.7 -0.5 -0.2 0.7 0.7 0.6 0.5 0.7 -0.3 0.8 1.3 0.9 1.2 0.5 0.7 0.8 0.8
Alcohol drinker status: Previous 0.3 0.3 0.9 0.7 -0.8 -0.4 -0.5 0.7 0.5 0.8 0.6 -0.8 -0.6 0.2 -0.2 -0.1 0.4 0.5 -0.4 0.4 0.5 0.5 0.7 -0.4 -0.3 0.1 1.0
Pack years of smoking 2.3 3.4 8.2 -0.1 -2.6 1.4 1.1 2.7 1.6 2.1 2.5 -2.8 -1.6 1.1 1.6 1.6 2.2 2.5 0.2 2.4 -0.4 2.0 0.4 1.1 -0.1 2.0 2.9
Impedance of whole body 10.0 50.8 93.1 4.3 -8.3 9.1 9.7 8.2 9.6 8.6 8.3 -7.4 -3.6 7.4 5.8 5.7 8.9 8.2 0.3 7.5 5.1 6.5 5.3 7.6 -0.2 6.9 8.1
Leg fat mass (left) 0.6 2.5 10.6 -1.6 1.5 -3.2 -3.3 -1.3 -2.0 -1.9 -1.4 0.9 2.0 -0.8 -0.5 -0.5 -1.9 -1.4 1.9 -1.1 0.3 -0.3 -1.3 -1.6 0.9 -0.9 -1.2
Arm predicted mass (left) 1.5 7.8 26.3 -5.1 3.3 -4.3 -4.2 -3.3 -4.2 -3.0 -2.9 2.4 2.1 -1.9 -0.2 0.2 -3.2 -2.8 -0.8 -2.3 -0.3 -2.1 -3.0 -1.4 1.8 -1.9 -2.9