TWAS hub - NT5DC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1070	0.0530	1.8e-04	0.052	0.038	0.043	0.043	0.041	6.2e-07	1.8e-05	5.0e-06	5.4e-06	8.6e-06
2	GTEx	Artery Aorta	0.0790	0.0440	2.6e-03	0.097	NA	0.057	NA	0.059	5.4e-06	NA	4.3e-04	NA	3.4e-04
3	GTEx	Breast Mammary Tissue	0.1310	0.0610	3.9e-04	0.122	NA	0.076	NA	0.069	8.1e-07	NA	9.9e-05	NA	2.0e-04
4	GTEx	Breast Mammary Tissue (Female)	0.0852	0.0608	4.8e-02	0.084	NA	0.016	NA	0.063	1.8e-03	NA	1.1e-01	NA	5.9e-03
5	GTEx	Cells EBV-transformed lymphocytes	0.1770	0.0940	5.5e-04	0.287	NA	0.199	NA	0.285	5.7e-10	NA	4.2e-07	NA	6.6e-10
6	GTEx	Cells Transformed fibroblasts	0.3040	0.0890	3.7e-10	0.166	NA	0.182	NA	0.144	1.6e-12	NA	1.3e-13	NA	5.9e-11
7	GTEx	Colon Sigmoid	0.0780	0.0510	9.1e-03	0.074	NA	0.057	NA	0.054	1.3e-03	NA	4.5e-03	NA	5.5e-03
8	GTEx	Colon Transverse	0.1190	0.0500	6.1e-06	0.182	NA	0.156	NA	0.170	4.6e-09	NA	7.0e-08	NA	1.7e-08
9	GTEx	Heart Atrial Appendage	0.0660	0.0360	2.6e-03	0.086	NA	0.050	NA	0.059	1.1e-04	NA	2.8e-03	NA	1.2e-03
10	GTEx	Heart Left Ventricle	0.1495	0.0832	5.0e-03	0.025	NA	0.043	NA	0.029	1.6e-02	NA	2.4e-03	NA	1.1e-02
11	GTEx	Nerve Tibial	0.0897	0.0438	2.3e-05	0.040	NA	0.049	NA	0.018	8.0e-04	NA	2.1e-04	NA	1.8e-02
12	GTEx	Skin Not Sun Exposed Suprapubic	0.2270	0.1180	1.8e-05	0.097	NA	0.077	NA	0.093	5.3e-06	NA	5.3e-05	NA	8.3e-06
13	GTEx	Skin Sun Exposed Lower leg	0.2070	0.0860	2.6e-11	0.189	NA	0.175	NA	0.173	1.7e-15	NA	2.0e-14	NA	2.8e-14
14	GTEx	Testis	0.1120	0.0560	1.2e-04	0.160	NA	0.113	NA	0.107	1.4e-07	NA	1.0e-05	NA	1.8e-05
15	GTEx	Thyroid	0.2050	0.0750	2.2e-08	0.133	NA	0.128	NA	0.130	2.4e-10	NA	5.1e-10	NA	4.0e-10
16	GTEx	Whole Blood	0.2870	0.1300	6.2e-06	0.043	NA	0.054	NA	0.029	8.0e-05	NA	9.0e-06	NA	9.6e-04
17	METSIM	Adipose	0.2680	0.0718	5.6e-17	0.128	0.091	0.140	0.118	0.140	1.1e-18	1.7e-13	2.2e-20	2.8e-17	2.6e-20
18	ROSMAP	Brain Pre-frontal Cortex	0.0828	0.0388	9.1e-06	0.006	0.028	0.015	0.026	0.018	5.6e-02	1.3e-04	4.2e-03	2.2e-04	2.0e-03
19	YFS	Blood	0.1641	0.0405	0.0e+00	0.080	0.084	0.111	0.082	0.112	6.0e-25	4.4e-26	1.7e-34	1.7e-25	9.5e-35
20	TCGA	Cervical Squamous Cell Carcinoma	0.1790	0.0970	6.2e-03	0.010	-0.001	-0.005	NA	-0.003	1.0e-01	3.4e-01	7.8e-01	NA	5.1e-01
21	TCGA	Colon Adenocarcinoma	0.0420	0.0280	8.2e-03	0.018	0.028	0.019	NA	0.016	3.1e-02	9.7e-03	2.7e-02	NA	3.9e-02
22	TCGA	Lung Squamous Cell Carcinoma	0.0679	0.0443	4.5e-03	0.015	0.008	0.022	NA	0.028	6.9e-03	3.8e-02	1.3e-03	NA	3.7e-04
23	TCGA	Prostate Adenocarcinoma	0.0342	0.0216	1.2e-03	0.030	0.028	0.013	NA	0.024	3.8e-04	6.1e-04	1.5e-02	NA	1.4e-03
24	TCGA	Thyroid Carcinoma	0.1910	0.0640	6.1e-16	0.192	0.154	0.176	NA	0.185	2.3e-18	8.6e-15	7.5e-17	NA	1.1e-17

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Waist Hip Ratio (WHR)	14.8	66.6	125.4	5.5	-10.1	10.1	10.6	10.4	10.1	11.2	10.1	-11.0	-3.3	6.4	5.6	6.2	10.2	9.7	-3.7	8.9	6.7	5.8	-1.1	5.3	-5.7	5.5	10.5
Worry (Nagel 2018)	14.6	30.8	48.0	-1.8	-6.6	6.8	6.3	6.6	5.6	6.8	6.7	-6.3	-4.7	6.1	5.6	5.9	6.9	6.7	0.3	5.3	3.2	5.6	3.0	5.7	0.7	5.5	6.4
Bipolar Disorder (2011)	10.8	10.4	22.0	-2.1	-3.1	4.4	4.7	3.1	3.7	3.9	3.5	-3.5	-2.2	4.0	3.8	3.9	3.8	3.6	0.9	2.2	1.6	3.3	0.0	4.3	2.4	0.0	3.3
Verbal and Numeric Reasoning (VNR)	10.6	25.4	40.3	0.1	6.2	-5.9	-5.3	-6.2	-5.1	-5.9	-6.3	6.0	2.4	-4.7	-5.6	-5.5	-6.1	-6.3	0.8	-5.7	-1.4	-5.1	-3.2	-5.3	0.5	-5.1	-6.3
Intelligence (Savage-Jansen 2018)	10.4	32.1	48.6	0.9	6.7	-5.9	-5.4	-6.7	-5.7	-6.2	-6.9	6.5	2.6	-6.2	-6.5	-6.5	-6.8	-7.0	-1.5	-6.2	-2.3	-6.2	-4.6	-6.5	-1.1	-6.2	-6.6
Worrier / anxious feelings	10.0	19.0	37.1	-0.6	-5.3	6.1	5.1	5.2	5.2	5.0	5.3	-4.4	-2.9	4.9	4.3	4.3	5.5	5.2	0.8	4.4	3.0	4.2	2.5	4.3	0.1	4.2	4.7
Impedance of whole body	10.0	50.8	93.1	4.3	-8.3	9.1	9.7	8.2	9.6	8.6	8.3	-7.4	-3.6	7.4	5.8	5.7	8.9	8.2	0.3	7.5	5.1	6.5	5.3	7.6	-0.2	6.9	8.1
Bipolar Disorder or Schizophrenia	9.4	23.0	54.3	-0.3	-5.1	7.4	7.3	5.3	5.7	6.1	5.5	-5.4	-4.0	5.0	4.2	4.5	6.0	5.4	-0.5	4.0	2.5	4.5	1.0	5.2	-0.0	4.8	5.0
Headache pain in last month	8.7	14.9	22.3	1.1	-4.0	3.7	3.8	4.2	4.4	4.4	4.3	-4.5	-0.3	4.7	4.5	4.5	4.3	4.5	1.6	4.4	4.2	4.0	2.1	4.1	1.0	4.2	4.6
Impedance of arm (left)	8.5	39.1	72.4	2.8	-7.0	7.8	8.5	6.9	8.2	7.4	7.1	-6.2	-3.1	7.0	5.4	5.4	7.7	7.1	0.9	6.2	4.5	6.0	5.2	7.3	1.1	6.4	6.9
Impedance of leg (left)	8.2	39.9	76.2	5.2	-7.7	8.2	8.5	7.6	8.7	7.7	7.5	-6.7	-2.8	5.7	4.7	4.5	7.9	7.4	-0.8	7.1	4.4	5.3	4.0	5.8	-1.9	5.6	7.2
Schizophrenia (2014)	8.1	17.9	40.4	-0.1	-4.7	6.4	6.1	4.9	4.9	5.3	5.0	-4.8	-3.6	4.4	3.6	3.8	5.4	4.9	0.4	3.6	1.8	4.0	1.4	4.4	-0.7	4.3	4.4
Nervous feelings	8.0	15.0	27.0	-0.9	-4.2	5.2	5.1	4.2	3.6	4.8	4.4	-4.3	-3.8	4.6	3.7	4.0	4.7	4.4	-0.3	3.6	2.3	3.9	1.8	4.2	0.7	3.8	4.2
Impedance of arm (right)	8.0	37.5	73.6	3.0	-6.9	7.8	8.6	6.8	8.1	7.3	7.0	-6.1	-2.9	6.6	5.2	5.2	7.7	7.0	0.9	6.0	4.7	5.6	4.8	7.0	0.5	6.1	6.7
Impedance of leg (right)	7.7	37.1	74.1	5.6	-7.3	7.7	8.1	7.4	8.6	7.3	7.2	-6.3	-2.4	5.5	4.5	4.2	7.6	7.1	-0.1	7.0	4.5	5.2	4.4	5.5	-1.8	5.4	6.9
Age when periods started (menarche)	7.2	17.2	35.0	-2.7	4.9	-5.2	-5.2	-5.2	-4.8	-5.9	-5.0	5.9	0.6	-4.2	-3.0	-3.3	-5.0	-4.8	0.8	-4.5	-4.0	-3.3	0.3	-2.7	1.9	-2.9	-5.6
Neuroticism	7.1	17.2	29.1	-2.2	-4.4	3.8	3.7	4.6	4.1	4.3	4.9	-4.5	-2.0	5.0	5.4	5.4	4.6	5.0	1.8	4.0	2.4	5.0	2.2	5.0	1.9	4.8	4.5
Age at First Birth	7.0	10.2	17.4	-2.6	3.7	-3.3	-2.6	-3.7	-3.9	-3.3	-3.7	3.4	-0.7	-3.2	-3.1	-2.9	-3.6	-3.7	-1.1	-4.2	-2.9	-3.9	-3.4	-2.8	0.9	-3.2	-3.5
Fluid intelligence score	6.6	13.7	21.5	0.8	4.6	-4.3	-3.3	-4.5	-3.3	-4.1	-4.6	4.3	2.4	-3.6	-4.0	-3.9	-4.4	-4.6	-0.0	-4.0	-1.0	-4.1	-3.7	-3.8	-0.7	-4.1	-4.6
Bipolar Disorder (2018)	6.5	10.3	22.8	0.5	-3.1	4.8	4.8	3.5	4.3	4.3	3.6	-3.9	-1.7	3.2	2.9	3.2	3.8	3.6	-0.7	2.5	2.5	2.8	0.2	3.4	0.1	3.0	3.5
Neuroticism (Nagel 2018)	6.5	15.3	24.4	-2.5	-4.4	3.6	3.2	4.5	3.5	4.0	4.7	-4.2	-2.3	4.5	4.8	4.9	4.5	4.8	1.0	4.0	2.3	4.6	2.5	4.6	1.8	4.4	4.2
Blood Red Count	6.4	61.5	102.0	1.3	-9.6	10.0	10.1	9.5	9.0	9.9	9.5	-9.3	-5.6	8.1	6.8	6.8	9.8	9.3	0.7	8.8	2.5	7.9	4.2	7.5	-2.3	7.6	9.2
Prospective memory result	6.4	7.8	12.9	-0.2	-3.2	2.8	2.7	3.0	2.4	3.3	3.2	-3.1	-1.0	3.0	3.3	3.4	3.2	3.3	0.3	3.6	1.7	2.9	2.6	3.4	0.8	3.2	3.3
Schizophrenia (2018)	6.3	13.0	31.5	-0.7	-4.0	5.6	5.5	4.0	3.9	4.4	4.1	-3.9	-3.7	3.9	3.0	3.1	4.6	4.1	-0.0	3.2	1.1	3.4	1.2	4.0	-0.1	3.8	3.6
Wears glasses or contact lenses	5.9	6.8	15.1	-2.1	3.0	-3.2	-3.7	-3.2	-2.4	-3.9	-3.1	3.7	0.0	-2.0	-1.8	-2.1	-3.3	-3.0	1.2	-3.3	-2.2	-1.8	-0.2	-1.8	1.4	-1.8	-3.5
Mouth/teeth dental problems: Bleeding gums	5.8	7.5	13.1	0.8	-3.4	3.3	3.4	3.6	3.1	3.2	3.5	-3.1	-2.0	2.0	2.3	2.2	3.6	3.5	-1.1	3.6	0.2	2.8	1.0	2.7	-1.2	2.7	3.0
Pulse rate	5.5	9.3	17.7	1.7	-3.6	4.2	3.9	3.6	3.8	4.1	3.6	-3.8	-1.2	2.7	2.4	2.6	3.6	3.5	-1.2	3.4	2.1	2.6	0.6	2.7	-1.9	2.5	3.7
Frequency of tenseness / restlessness in last 2 weeks	5.3	8.2	17.0	-1.8	-3.3	2.6	2.3	3.2	2.6	3.4	3.5	-3.3	-1.5	3.1	4.0	4.1	3.2	3.5	0.3	3.0	1.7	2.8	1.2	3.1	1.1	3.0	3.4
Ever highly irritable/argumentative for 2 days	5.1	6.1	10.4	0.1	2.6	-3.2	-3.2	-2.5	-2.1	-2.7	-2.6	2.4	1.8	-2.8	-2.4	-2.3	-3.0	-2.6	-0.8	-2.2	-1.1	-3.0	-2.8	-2.8	-1.6	-3.0	-2.6
BMI	5.0	29.1	74.5	-2.9	6.2	-8.6	-8.3	-6.0	-7.0	-7.0	-6.0	5.7	5.3	-4.7	-3.5	-3.7	-6.9	-5.9	2.3	-5.3	-2.8	-3.6	-2.9	-5.3	0.5	-4.4	-6.1
Myopia	4.9	7.1	13.2	0.2	3.0	-2.5	-2.4	-3.3	-1.9	-2.7	-3.3	3.1	1.4	-2.7	-3.0	-2.9	-3.2	-3.3	-1.6	-3.6	-1.3	-3.3	-2.2	-2.8	-0.4	-3.2	-3.0
Glaucoma (self-reported)	4.8	5.6	12.6	1.6	-3.5	2.8	2.3	3.1	2.5	2.7	3.0	-2.7	-1.0	1.5	2.1	2.0	3.0	3.0	0.9	2.8	1.5	2.3	2.1	1.7	-1.6	2.0	2.8
Suffer from ‘nerves’	4.7	7.4	15.5	-3.3	-2.5	2.6	2.2	2.6	1.8	2.8	3.0	-2.9	-2.7	3.2	3.7	3.9	2.7	3.1	-0.1	2.1	0.7	3.0	0.7	3.7	1.9	3.0	2.9
Stomach or abdominal pain in last month	4.6	5.7	9.7	0.3	-2.8	3.1	2.8	3.1	2.6	3.1	3.1	-3.0	-1.3	2.5	2.3	2.5	2.9	3.0	-0.5	2.8	1.2	1.9	-0.2	2.0	-0.7	2.0	2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	4.6	6.0	9.7	-1.2	-2.9	2.5	1.8	3.0	2.6	3.0	3.1	-3.1	-1.1	2.9	2.9	3.1	2.9	3.1	-0.4	2.7	1.8	2.2	-0.3	2.3	0.3	2.1	3.1
Ever smoked	4.6	8.1	13.7	1.1	3.3	-3.3	-3.3	-3.1	-3.2	-3.3	-3.2	3.1	1.7	-3.7	-2.6	-2.9	-3.5	-3.2	-1.5	-2.6	-2.3	-2.8	-1.6	-3.3	-1.2	-2.9	-3.2
Number of incorrect matches in round	4.3	7.2	13.5	-0.0	-2.5	2.9	2.3	2.6	2.8	2.3	2.7	-2.4	-1.5	3.2	3.0	2.8	2.7	2.8	2.8	2.1	2.0	3.7	3.1	3.1	2.6	3.3	2.8
Guilty feelings	4.3	6.4	10.8	-0.4	-2.7	2.5	2.0	3.0	2.4	2.8	3.2	-3.0	-1.2	2.0	3.3	3.3	2.8	3.2	0.1	3.2	0.7	2.8	1.4	3.0	1.0	3.0	3.0
Basal cell carcinoma (self-reported)	4.2	4.9	7.8	0.7	-2.8	2.7	2.4	2.7	2.7	2.8	2.8	-2.5	-0.6	2.4	2.1	2.2	2.7	2.7	-0.3	2.8	1.8	1.9	0.4	2.0	-1.9	1.7	2.4
Major Depression (MDD)	4.1	5.0	7.5	-1.6	-2.5	2.7	2.7	2.5	2.2	2.3	2.6	-2.7	-1.8	1.8	2.7	2.7	2.7	2.7	-0.2	2.0	0.2	2.3	0.3	2.6	0.3	2.5	2.5
Illness, injury, bereavement, stress in last 2 years	4.1	5.0	11.2	-1.6	2.8	-2.3	-2.2	-2.9	-3.3	-2.7	-2.8	2.7	-0.1	-2.1	-1.9	-2.0	-2.5	-2.7	-0.8	-2.3	-1.9	-1.9	-0.2	-1.6	2.2	-2.0	-2.5
Average weekly champagne plus white wine intake	4.0	5.4	10.4	-1.0	2.8	-2.4	-2.5	-2.7	-2.8	-2.9	-2.8	3.1	0.3	-2.1	-2.5	-2.6	-2.9	-2.8	-0.6	-3.2	-1.2	-2.3	-0.3	-2.1	1.1	-2.0	-2.8
Tense / ‘highly strung’	3.9	6.5	10.4	-2.8	-2.7	3.1	3.2	2.6	2.2	3.1	2.9	-2.4	-2.2	3.0	2.9	3.2	3.2	2.9	0.5	1.9	1.4	2.5	0.8	3.0	1.2	2.7	2.2
Ulcerative Colitis	3.8	5.5	10.2	-2.3	-2.5	2.1	1.6	2.5	1.6	2.4	2.6	-2.7	-3.2	2.7	2.6	2.7	2.6	2.6	1.2	1.5	1.1	2.7	1.1	2.4	2.2	2.8	2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	3.7	5.6	10.9	-1.2	-2.3	3.3	3.3	2.3	2.4	3.0	2.5	-2.6	-1.4	3.2	2.6	2.9	2.6	2.5	0.5	2.1	1.8	2.6	0.0	2.5	1.2	2.4	2.5
Pulse wave reflection index	3.7	4.5	9.4	-2.1	2.3	-3.1	-2.8	-2.4	-2.8	-2.5	-2.4	2.3	1.3	-2.0	-1.6	-1.4	-2.5	-2.4	0.6	-2.9	-0.6	-1.8	-1.8	-1.9	0.5	-1.7	-2.6
Pulse rate, automated reading	3.7	11.9	27.8	4.3	-4.2	5.3	5.2	4.2	4.8	4.8	3.9	-4.1	-1.1	1.6	0.8	1.0	4.0	3.6	-2.3	3.9	1.2	2.1	-0.0	1.5	-4.4	1.6	3.9
Neuroticism score	3.6	7.4	16.9	-2.2	-2.8	2.1	2.0	3.0	2.0	2.8	3.2	-2.9	-1.3	3.3	4.0	4.1	2.9	3.4	0.9	2.9	1.9	3.1	0.8	3.3	1.3	3.0	2.9
Family relationship satisfaction	3.6	4.4	13.2	-0.1	-1.9	3.0	3.6	2.0	2.3	2.9	2.3	-1.9	-0.7	2.2	2.0	2.2	2.4	2.2	-1.5	2.1	1.3	1.9	1.4	2.8	0.0	1.9	1.9
Smoking Status	3.4	8.2	19.4	2.7	2.5	-3.9	-4.3	-2.5	-2.9	-2.8	-2.9	2.0	3.1	-3.7	-2.9	-3.1	-3.4	-2.9	-1.4	-1.8	-0.7	-2.8	-2.0	-4.4	-1.5	-3.2	-2.1
Average weekly spirits intake	3.3	4.1	8.3	-1.4	2.5	-2.6	-2.3	-2.7	-2.9	-2.6	-2.5	2.3	1.1	-2.1	-1.6	-1.4	-2.6	-2.5	0.0	-2.6	-0.2	-1.4	-0.9	-1.4	0.4	-1.6	-2.6
Multivitamins +/- minerals	3.3	4.1	9.2	0.2	2.3	-2.7	-2.6	-2.4	-1.3	-2.5	-2.3	2.2	3.0	-1.9	-1.4	-1.4	-2.6	-2.3	-0.1	-1.9	-0.8	-2.4	-2.1	-1.8	0.1	-2.1	-2.2
Happiness	3.3	4.1	10.2	-2.1	-1.4	1.3	1.4	1.6	1.6	1.7	1.9	-1.2	-0.5	2.5	2.9	3.0	1.8	2.0	1.6	1.8	0.9	2.5	2.5	3.2	2.1	2.8	1.4
HDL Cholesterol	3.2	5.3	20.1	-4.5	3.1	-2.0	-2.0	-3.1	-2.0	-3.0	-2.5	3.6	1.6	-0.3	-0.2	-0.3	-2.3	-2.3	0.7	-2.6	-1.6	-1.0	0.1	0.6	3.6	-0.6	-3.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.2	3.8	11.3	-1.0	-1.8	0.2	0.1	2.0	1.2	1.5	2.2	-1.9	-0.6	1.8	3.4	3.3	1.7	2.4	2.4	1.6	1.2	2.5	1.3	2.4	0.8	2.8	2.1
Frequency of tiredness / lethargy in last 2 weeks	3.1	5.1	11.4	0.6	-2.7	2.0	1.8	2.8	2.0	3.0	2.8	-3.0	-0.4	1.9	2.7	3.0	2.6	2.8	-0.9	3.4	2.3	1.7	-0.6	1.5	-0.4	1.6	3.0
Depression (self-reported)	3.1	3.7	8.0	-1.5	-1.9	2.5	2.1	2.2	2.0	2.1	2.4	-1.5	-0.2	2.3	2.8	2.8	2.3	2.5	1.0	1.6	1.4	1.6	0.4	1.9	-0.2	1.9	1.6
Medication: Paracetamol	3.1	5.1	10.2	1.4	-2.6	3.0	2.4	2.7	2.5	3.1	2.6	-3.2	-0.7	1.8	1.7	2.1	2.7	2.6	-1.7	2.6	2.7	1.6	-0.9	1.3	-1.3	1.5	2.9
Rheumatoid Arthritis	3.0	4.1	8.8	-0.5	2.3	-1.9	-1.5	-2.2	-2.3	-2.3	-2.2	2.5	0.9	-3.0	-2.0	-2.1	-2.1	-2.2	-1.2	-1.7	-2.8	-2.2	-1.5	-1.8	-1.0	-2.3	-2.5
Pack years adult smoking proportion	3.0	4.5	11.4	0.6	-2.9	1.9	1.6	3.1	1.9	2.7	2.9	-3.4	-1.3	1.0	1.8	1.8	2.5	2.9	-0.2	2.9	-0.3	2.0	0.3	1.1	-0.7	2.0	3.4
Body mass index (BMI)	3.0	13.0	33.2	-2.0	3.9	-5.6	-5.8	-3.7	-4.8	-4.3	-3.9	3.2	2.8	-3.6	-2.8	-2.9	-4.5	-3.9	1.3	-3.5	-2.2	-2.6	-2.8	-4.3	0.2	-3.3	-3.5
Comparative body size at age 10	3.0	8.3	21.3	0.3	3.3	-3.2	-3.1	-2.9	-2.3	-2.8	-3.0	2.6	3.9	-3.0	-2.4	-2.2	-3.2	-2.9	-1.8	-2.6	-0.4	-3.4	-4.6	-3.3	-1.3	-3.5	-2.9
Neuroticism (2016)	2.9	4.1	7.3	-2.1	-2.2	1.9	1.7	1.8	1.5	2.3	2.1	-2.2	-2.5	2.2	2.5	2.7	2.2	2.2	-0.2	1.9	1.3	2.3	0.6	2.5	1.1	2.2	2.2
Relative age voice broke	2.9	4.5	7.6	0.2	2.2	-2.4	-2.7	-2.1	-2.1	-2.6	-2.2	2.5	0.3	-2.5	-2.3	-2.3	-2.3	-2.2	-1.8	-2.4	-1.0	-2.2	-1.4	-2.4	-0.4	-2.2	-2.7
Gout (self-reported)	2.9	3.9	13.5	-1.4	-2.4	2.4	2.1	2.3	0.4	2.4	2.3	-2.5	-3.7	1.6	1.7	1.9	2.2	2.3	-0.7	1.9	-0.7	2.0	0.5	1.5	-0.3	1.7	2.6
Eye problems/disorders: None of the above	2.9	3.4	8.5	1.3	1.9	-1.0	-0.6	-2.2	-1.3	-1.4	-2.3	1.9	0.3	-2.2	-2.9	-2.7	-2.0	-2.5	-1.5	-2.1	-1.3	-2.0	-1.1	-2.1	0.3	-2.1	-1.9
Medication: Blood pressure	2.9	5.1	10.2	-2.6	2.6	-2.6	-2.6	-2.5	-2.8	-3.0	-2.4	3.2	0.4	-1.1	-1.5	-1.8	-2.4	-2.4	1.9	-3.2	-2.1	-1.5	-0.8	-1.7	1.2	-1.5	-3.0
Chest pain or discomfort	2.9	4.1	6.6	-1.1	-2.2	2.6	2.4	2.5	2.1	2.3	2.5	-2.4	-1.6	1.4	2.2	2.2	2.6	2.6	-0.9	2.0	-0.0	2.2	0.5	2.3	0.0	2.2	2.3
Back pain experienced in last month	2.9	4.3	8.1	-0.8	1.9	-2.3	-2.1	-2.1	-2.6	-1.9	-2.2	1.8	0.6	-2.9	-2.0	-1.9	-2.0	-2.2	-2.0	-1.7	-1.0	-2.7	-2.9	-2.4	-0.8	-2.6	-1.9
Height	2.8	53.3	134.6	-7.0	-5.7	4.8	6.0	5.5	6.3	6.2	6.9	-6.0	-2.2	9.3	11.0	11.6	7.5	7.4	1.6	6.9	7.9	7.6	3.8	11.4	7.5	9.0	6.1
Past tobacco smoking	2.8	5.1	10.8	-1.9	-2.4	3.3	3.3	2.2	2.4	2.5	2.4	-2.1	-2.5	2.9	1.9	2.2	2.7	2.4	0.6	1.5	0.7	2.0	1.1	2.9	1.0	2.3	2.1
Primary Biliary Cirrhosis	2.7	3.8	7.2	0.7	2.1	-1.7	-1.6	-2.0	-2.0	-1.9	-2.1	1.9	0.9	-2.7	-2.5	-2.5	-2.1	-2.2	-1.7	-1.6	-1.4	-2.3	-1.5	-2.3	-1.5	-2.3	-2.1
Triglycerides	2.7	4.5	18.7	4.3	-2.6	1.3	1.0	2.4	2.4	2.5	2.1	-3.3	0.3	1.2	0.6	0.7	1.8	1.9	-0.4	3.0	3.5	1.4	0.7	-0.0	-1.5	0.7	3.1
Migraine (self-reported)	2.6	3.2	6.0	-0.3	-1.6	2.1	2.5	1.8	2.0	1.7	1.9	-1.8	-1.0	1.8	2.0	1.9	2.1	2.0	1.6	2.1	-0.7	2.1	1.2	2.5	0.4	2.3	1.5
Type 2 Diabetes (T2D) (2012)	2.5	2.8	7.4	0.9	-1.8	0.9	1.3	2.7	1.1	2.4	2.6	-2.3	-1.5	0.7	1.1	1.3	2.2	2.3	-1.3	2.1	1.0	1.4	0.0	1.0	-1.7	1.1	2.3
Illnesses of mother	2.5	3.1	5.5	0.6	2.1	-1.7	-1.3	-2.1	-1.5	-1.9	-2.1	2.1	1.8	-2.0	-1.8	-2.0	-2.0	-2.0	-0.6	-1.6	-1.3	-2.3	-1.2	-1.5	-1.1	-2.0	-2.0
Wheeze or whistling in the chest in last year	2.5	4.5	8.1	-0.7	-2.4	1.4	1.3	2.4	1.6	2.6	2.6	-2.7	-0.7	2.5	2.7	2.8	2.2	2.6	0.0	2.6	1.3	2.3	1.1	2.5	0.4	2.4	2.8
Eye problems/disorders: Cataract	2.5	2.9	7.6	-1.6	-1.5	1.0	0.7	1.9	1.9	1.0	2.0	-1.2	0.6	2.2	2.8	2.5	1.7	2.2	2.2	1.8	0.7	1.5	0.4	2.2	-0.3	2.2	1.3
LDL Cholesterol	2.4	3.9	10.7	3.0	1.1	-1.5	-1.2	-1.4	-1.1	-0.9	-1.8	1.1	0.6	-2.4	-3.1	-3.0	-1.6	-2.0	-2.1	-1.4	-0.4	-2.6	-1.1	-3.3	-2.3	-2.7	-1.1
Lung FEV1/FVC ratio	2.4	12.2	26.5	-2.8	3.6	-4.4	-4.7	-3.5	-3.6	-4.6	-3.7	4.1	-0.2	-3.5	-3.1	-3.4	-3.9	-3.7	0.2	-5.2	-1.9	-3.3	-2.7	-3.8	-0.4	-3.5	-4.0
Systolic blood pressure, automated reading	2.4	7.1	18.0	-1.8	2.8	-2.7	-3.1	-2.5	-4.2	-3.1	-2.9	2.5	-1.5	-2.7	-2.8	-2.9	-2.8	-2.9	-1.1	-3.4	-2.0	-2.3	-1.7	-3.4	1.3	-2.9	-2.4
High blood pressure (mother)	2.4	3.3	5.8	0.5	-2.2	2.4	1.9	2.2	2.1	2.4	2.1	-2.2	-0.6	2.1	1.6	1.8	2.2	2.1	0.2	2.0	2.4	1.8	0.2	0.9	0.3	1.5	2.2
Alcohol intake versus 10 years previously	2.4	3.6	7.4	0.1	2.0	-2.7	-2.4	-2.0	-2.5	-2.3	-2.1	2.1	0.3	-2.7	-1.9	-2.1	-2.2	-2.1	0.7	-2.1	-1.5	-1.6	0.3	-1.7	-0.2	-1.6	-2.0
Tinnitus: Yes, now most or all of the time	2.4	2.9	6.2	-0.2	-2.1	2.1	1.9	1.8	1.5	2.0	1.9	-1.9	-2.5	1.6	1.3	1.4	2.1	1.9	1.2	1.2	0.1	2.2	1.2	1.9	-0.0	2.0	1.8
Pack years of smoking	2.3	3.4	8.2	-0.1	-2.6	1.4	1.1	2.7	1.6	2.1	2.5	-2.8	-1.6	1.1	1.6	1.6	2.2	2.5	0.2	2.4	-0.4	2.0	0.4	1.1	-0.1	2.0	2.9
Serious illness, injury or assault to yourself	2.2	2.7	6.7	1.5	-2.0	2.1	1.8	2.0	2.6	2.1	1.9	-2.1	0.1	1.0	1.1	1.2	1.8	1.8	-0.6	1.7	1.9	0.7	-0.4	0.7	-2.0	0.9	1.9
Medication for cholesterol, blood pressure or diabetes	2.2	3.7	7.6	1.5	-2.2	2.3	2.4	2.2	2.3	2.6	2.2	-2.8	-0.8	0.8	1.5	1.7	2.2	2.1	-1.8	2.6	1.1	1.2	-0.2	1.7	-1.2	1.4	2.6
Friendships satisfaction	2.2	2.7	7.1	-1.7	-0.9	1.9	2.1	1.2	1.8	1.5	1.5	-1.2	-0.4	2.1	2.2	2.3	1.6	1.6	0.3	1.3	0.0	1.9	1.2	2.7	1.9	2.1	0.9
Medication: Bendroflumethiazide	2.2	3.3	7.0	-0.6	1.8	-1.9	-2.1	-1.9	-2.0	-1.7	-2.1	1.5	-0.6	-1.8	-2.1	-2.0	-1.9	-2.1	-1.5	-2.1	-0.6	-2.0	-1.8	-2.6	1.6	-2.3	-1.4
Alcohol drinker status: Never	2.2	2.6	5.0	0.1	-1.9	1.6	1.4	2.0	1.3	1.6	1.9	-1.4	-1.1	1.9	1.6	1.5	1.9	2.0	2.2	1.4	1.8	1.8	1.3	1.1	0.9	1.8	1.7
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	9.8	2.8	-1.9	1.1	0.4	1.9	1.9	1.7	1.7	-2.2	0.3	1.2	0.7	0.9	1.3	1.6	-0.2	1.5	3.1	1.3	-0.3	-0.2	-0.9	0.6	2.2
Illnesses of siblings: Diabetes	2.1	2.6	5.6	-0.6	1.6	-1.2	-0.9	-1.8	-1.4	-1.4	-1.8	1.7	0.1	-1.6	-1.7	-1.7	-1.5	-1.8	-1.9	-2.2	-2.4	-2.1	-1.6	-1.4	-1.1	-1.8	-1.7
Mineral and other dietary supplements	2.1	2.8	5.8	-1.1	-1.5	2.4	2.2	1.7	1.9	1.5	1.8	-1.1	-1.9	2.1	1.3	1.1	2.0	1.8	0.7	1.3	-0.8	1.9	1.8	2.1	1.4	1.9	1.3
Standing height	2.0	19.7	54.8	-4.6	-3.0	3.1	4.0	2.8	3.9	3.9	3.9	-3.4	-0.5	6.0	6.7	7.3	4.3	4.2	-0.9	4.4	5.5	3.5	1.7	7.4	4.5	5.0	3.6
Commuting to job workplace: Cycle	2.0	2.4	5.7	-1.1	1.5	-1.4	-1.6	-1.5	-1.8	-2.0	-1.6	2.1	-1.0	-1.8	-1.5	-1.8	-1.5	-1.6	1.1	-1.9	-2.4	-1.2	0.8	-1.0	0.1	-1.2	-1.9
Blood Eosinophil Count	1.9	14.3	32.6	0.9	3.4	-5.7	-5.1	-3.6	-5.5	-3.9	-3.9	2.7	1.2	-4.6	-3.8	-3.8	-4.3	-3.9	-2.2	-2.6	-2.6	-4.3	-3.2	-4.7	-2.7	-4.6	-2.8
Systolic Blood Pressure	1.9	9.7	19.8	-0.9	3.2	-3.1	-3.2	-3.0	-4.5	-3.2	-3.4	3.0	-1.4	-3.0	-3.8	-3.8	-3.2	-3.4	-1.7	-4.2	-1.0	-3.2	-2.6	-4.3	0.9	-3.8	-2.8
Hip circumference	1.9	8.3	17.9	-3.1	3.7	-4.2	-4.2	-3.5	-3.6	-3.7	-3.4	2.9	2.0	-2.1	-1.7	-1.7	-3.7	-3.3	1.1	-2.9	-1.7	-1.9	-2.0	-2.3	2.0	-2.3	-3.1
Breastfed as a baby	1.9	2.4	7.5	-0.8	2.0	-1.8	-1.5	-1.8	-1.3	-1.8	-1.8	1.5	-0.6	-2.2	-1.2	-1.4	-1.8	-1.7	0.1	-2.4	-2.7	-1.0	-0.0	-0.9	1.0	-0.9	-1.5
Comparative height size at age 10	1.9	10.6	26.9	-2.3	-2.5	2.4	3.1	2.5	3.2	3.7	3.2	-3.5	0.3	3.7	4.6	5.2	3.4	3.4	-1.2	3.2	4.7	2.2	0.2	5.0	1.8	3.1	3.5
Hearing aid user	1.9	2.1	4.8	0.4	1.5	-2.0	-2.1	-1.5	-1.9	-1.7	-1.7	1.0	0.6	-1.5	-1.5	-1.6	-1.7	-1.6	0.0	-1.1	-0.8	-1.5	-1.1	-2.2	0.1	-1.8	-1.2
Eye problems/disorders: Glaucoma	1.9	2.3	4.7	0.7	-2.2	2.1	1.8	1.9	1.2	1.7	1.9	-1.6	-1.5	0.4	1.2	1.1	2.0	1.9	-0.1	1.6	0.0	1.4	1.4	1.2	-1.3	1.2	1.8
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	5.2	-0.1	-1.9	0.8	1.6	1.8	1.1	1.9	1.9	-1.8	-0.8	1.4	2.3	2.2	2.0	2.1	0.2	1.2	0.7	1.5	0.6	1.8	-1.1	1.7	1.9
Blood clot in the leg (DVT)	1.8	2.3	4.9	0.1	-1.8	0.9	1.6	1.8	1.1	1.8	1.9	-1.6	-0.7	1.4	2.2	2.1	1.9	2.0	0.3	1.1	0.7	1.5	0.8	1.7	-1.4	1.7	1.7
Medication for pain relief, constipation, heartburn	1.8	3.2	9.3	0.0	2.1	-1.4	-1.0	-2.1	-1.6	-2.4	-2.1	2.3	0.9	-1.7	-2.1	-2.5	-1.9	-2.1	0.5	-1.5	-3.1	-1.7	0.4	-0.9	-0.2	-1.5	-2.3
Medication: Allopurinol	1.8	2.4	4.5	-0.6	-2.1	1.8	1.6	2.1	0.3	1.8	2.0	-2.0	-2.1	1.0	1.5	1.5	1.9	2.0	-0.4	1.7	-0.4	1.8	1.0	1.2	-0.8	1.4	2.1
Mood swings	1.8	3.2	11.6	-3.1	-1.1	0.1	0.2	1.4	0.7	1.1	1.8	-1.4	0.1	2.1	3.3	3.4	1.2	1.9	1.6	1.6	0.4	2.1	0.2	2.6	1.5	2.1	1.3
Diabetes diagnosed by doctor	1.8	2.9	7.3	0.9	1.3	-2.1	-1.9	-1.4	-1.8	-1.9	-1.7	1.6	0.4	-2.2	-2.2	-2.3	-1.8	-1.8	-0.8	-1.9	-1.4	-1.3	-0.7	-2.7	-0.8	-2.0	-1.6
Ever used hormone-replacement therapy (HRT)	1.7	2.1	8.0	2.4	-1.5	1.3	0.9	1.8	1.7	2.2	1.4	-2.3	-1.0	0.5	-0.0	0.3	1.2	1.3	-1.6	0.9	2.8	0.7	-0.4	-0.9	-0.3	0.2	2.2
Vitamin and mineral supplements	1.7	2.3	4.0	1.2	-1.8	1.7	1.7	2.0	1.2	2.0	1.9	-1.9	-1.2	0.8	0.9	0.8	1.9	1.8	-0.0	1.9	-0.2	1.8	1.9	1.1	-0.4	1.4	1.9
Number of full brothers	1.7	2.2	3.9	0.9	1.8	-1.8	-1.9	-1.8	-1.3	-1.6	-1.8	1.7	1.9	-0.8	-1.5	-1.6	-2.0	-1.8	-0.4	-1.5	0.2	-1.6	0.1	-1.4	0.7	-1.4	-1.4
Supplements: Fish oil (including cod liver oil)	1.7	2.2	5.5	0.3	1.5	-2.3	-2.0	-1.6	-1.9	-1.5	-1.7	1.4	1.3	-1.7	-1.1	-1.0	-1.8	-1.7	0.1	-1.5	0.7	-1.6	-1.2	-1.9	-0.7	-1.7	-1.4
Depressed Affect (Nagel 2018)	1.6	3.3	11.5	-2.6	-1.5	0.0	-0.3	1.5	0.6	0.8	1.8	-1.4	0.3	1.9	3.4	3.3	1.3	2.0	1.7	2.1	0.4	2.3	1.1	2.5	1.7	2.2	1.5
Depression (Nagel 2018)	1.6	2.4	5.5	-1.2	-1.6	2.0	1.8	1.5	1.6	2.3	1.7	-1.8	-1.2	1.5	1.6	1.9	2.0	1.7	-0.9	1.7	0.7	0.7	-0.8	2.0	0.1	1.0	1.8
Prostate Cancer	1.6	2.2	4.8	-0.6	-1.9	1.1	0.7	1.7	1.2	1.3	1.8	-1.4	-1.0	1.4	2.2	2.0	1.6	1.9	1.5	1.3	0.7	1.5	1.5	1.7	-0.6	1.9	1.6
Sensitivity / hurt feelings	1.6	2.7	5.4	-0.2	-1.7	2.1	2.3	2.0	1.7	1.8	2.0	-1.7	-1.7	1.9	1.7	1.6	2.0	2.1	0.2	1.5	1.5	1.8	0.7	1.5	-0.0	1.5	1.6
Leg fat-free mass (left)	1.6	8.3	28.4	-5.3	3.6	-4.6	-4.5	-3.5	-4.0	-3.3	-3.0	2.6	2.5	-1.3	-0.0	0.3	-3.4	-2.8	0.5	-2.4	-0.2	-1.7	-2.3	-0.9	2.9	-1.5	-2.8
Leg predicted mass (left)	1.6	8.3	29.1	-5.4	3.6	-4.7	-4.5	-3.5	-4.0	-3.3	-3.0	2.6	2.5	-1.3	0.0	0.3	-3.4	-2.8	0.5	-2.4	-0.2	-1.7	-2.3	-0.9	2.8	-1.5	-2.9
Alcohol usually taken with meals	1.6	2.6	7.7	1.2	-1.4	2.1	1.8	1.4	2.8	1.4	1.5	-0.9	1.5	2.1	1.5	1.4	1.5	1.5	0.5	1.8	2.5	1.1	1.7	1.7	-0.5	1.6	1.0
Trunk predicted mass	1.6	8.9	32.2	-5.7	3.8	-4.3	-4.1	-3.8	-4.3	-3.4	-3.2	3.0	2.3	-1.8	0.0	0.4	-3.4	-3.0	-1.2	-2.3	-0.5	-2.4	-2.8	-0.9	2.4	-1.8	-3.3
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.4	9.5	-1.5	-1.1	1.8	2.2	1.2	1.4	1.9	1.6	-1.8	-0.6	2.0	2.8	3.0	1.9	1.8	-0.7	2.0	1.6	1.6	0.3	3.1	1.6	2.0	1.6
Whole body water mass	1.6	9.0	32.4	-5.7	3.7	-4.5	-4.4	-3.7	-4.3	-3.3	-3.2	2.8	2.4	-1.6	0.0	0.4	-3.5	-3.0	-0.7	-2.4	-0.2	-2.2	-2.7	-1.0	2.5	-1.8	-3.1
Illnesses of father: High blood pressure	1.6	2.0	12.5	-2.7	1.0	-0.5	-0.9	-0.9	-1.9	-1.7	-0.9	1.5	-2.1	-1.5	-0.3	-0.6	-0.8	-0.8	0.4	-1.6	-3.5	-0.7	-1.1	-0.6	0.3	-0.7	-1.6
Fractured/broken bones in last 5 years	1.6	2.1	4.8	-0.3	1.8	-1.1	-0.8	-1.7	-1.3	-1.2	-1.7	1.0	-0.3	-1.5	-1.6	-1.5	-1.6	-1.7	-1.3	-2.0	-0.9	-2.0	-2.2	-1.6	0.3	-1.9	-1.0
Breast Cancer	1.5	3.7	9.0	0.8	2.6	-1.9	-1.3	-2.6	-1.5	-2.0	-2.5	2.4	3.0	-1.0	-1.9	-1.7	-2.3	-2.4	1.2	-1.6	0.2	-2.0	-0.9	-1.7	0.9	-2.1	-2.6
Lung FVC	1.5	7.6	19.3	0.7	1.7	-1.2	-2.0	-1.9	-2.6	-1.8	-2.4	1.7	-2.9	-4.4	-3.8	-3.7	-2.1	-2.5	-2.8	-2.7	-3.9	-3.3	-3.1	-3.9	-2.2	-3.3	-1.6
Sitting height	1.5	10.7	32.5	-4.9	-1.4	1.6	2.0	1.2	1.6	2.2	2.1	-2.4	-0.9	4.7	5.2	5.7	2.4	2.4	0.3	2.9	4.0	2.7	1.1	5.2	5.7	3.5	2.4
Allergy	1.5	3.4	6.4	-1.1	1.8	-1.9	-2.5	-1.9	-1.7	-2.5	-2.0	2.4	1.3	-1.8	-1.6	-1.6	-2.0	-2.0	0.0	-1.7	-1.1	-2.3	-1.6	-2.1	0.9	-1.8	-2.2
Diabetes (self-reported)	1.5	2.3	5.0	0.7	1.3	-2.2	-2.2	-1.3	-1.5	-1.7	-1.5	1.4	0.6	-1.9	-1.6	-1.8	-1.7	-1.5	-0.5	-1.7	-1.7	-1.2	-0.7	-2.2	-0.7	-1.6	-1.3
Trunk fat-free mass	1.5	8.6	30.8	-5.6	3.7	-4.2	-4.1	-3.7	-4.2	-3.3	-3.2	2.9	2.2	-1.7	0.0	0.5	-3.3	-2.9	-1.2	-2.3	-0.4	-2.3	-2.8	-0.9	2.3	-1.8	-3.2
Medication: Amlodipine	1.5	2.0	5.3	-1.1	0.9	-0.9	-1.7	-1.0	-2.0	-1.1	-1.2	1.0	-2.3	-0.9	-1.8	-1.6	-1.2	-1.3	-1.7	-1.7	-0.9	-1.3	-1.5	-2.2	1.0	-1.6	-0.8
Arm predicted mass (right)	1.5	7.6	26.2	-5.1	3.4	-4.2	-4.2	-3.4	-4.0	-3.2	-2.9	2.6	2.0	-1.7	-0.1	0.2	-3.2	-2.8	-0.5	-2.1	-0.7	-2.0	-2.4	-1.1	2.2	-1.6	-3.0
Whole body fat-free mass	1.5	8.5	32.3	-5.7	3.6	-4.4	-4.3	-3.6	-4.2	-3.3	-3.1	2.7	2.4	-1.6	0.1	0.5	-3.3	-2.9	-0.7	-2.2	-0.4	-2.1	-2.6	-0.9	2.5	-1.7	-3.0
Leg fat-free mass (right)	1.5	7.8	32.8	-5.7	3.4	-4.3	-4.2	-3.4	-4.0	-3.1	-2.9	2.3	2.3	-1.1	0.1	0.5	-3.2	-2.7	-0.0	-2.3	-0.3	-1.7	-2.6	-0.7	2.7	-1.4	-2.7
Leg predicted mass (right)	1.5	7.8	31.4	-5.6	3.4	-4.3	-4.2	-3.4	-4.0	-3.1	-2.9	2.3	2.3	-1.2	0.1	0.4	-3.2	-2.7	-0.1	-2.3	-0.2	-1.8	-2.6	-0.8	2.6	-1.5	-2.7
Arm predicted mass (left)	1.5	7.8	26.3	-5.1	3.3	-4.3	-4.2	-3.3	-4.2	-3.0	-2.9	2.4	2.1	-1.9	-0.2	0.2	-3.2	-2.8	-0.8	-2.3	-0.3	-2.1	-3.0	-1.4	1.8	-1.9	-2.9
Hand grip strength (left)	1.4	3.7	9.1	-0.8	-1.1	2.4	2.0	1.0	2.9	1.3	1.5	-0.8	1.6	2.8	2.8	2.8	1.6	1.6	1.3	2.2	1.8	1.9	1.5	3.0	1.3	2.3	0.7
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.9	-1.8	-1.1	1.4	1.4	1.1	0.6	2.1	1.4	-1.7	-1.1	1.1	1.9	2.2	1.5	1.4	-1.4	1.0	0.7	0.4	-1.4	1.6	0.2	0.7	1.7
Pain all over the body in last month	1.4	1.6	2.8	-0.3	-1.6	0.5	0.3	1.5	1.7	1.6	1.6	-1.5	0.2	1.6	1.3	1.4	1.3	1.5	-0.3	1.2	0.1	1.5	0.9	1.3	0.9	1.5	1.6
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	3.7	0.2	-1.6	1.9	1.9	1.5	1.6	1.6	1.5	-1.4	-1.8	1.8	0.7	0.7	1.7	1.4	0.1	1.0	0.8	1.5	1.5	1.2	0.4	1.3	1.4
Medication: Cholesterol lowering	1.4	2.1	4.9	-0.4	1.3	-2.0	-2.2	-1.4	-1.4	-1.9	-1.5	2.1	0.1	-0.6	-1.3	-1.5	-1.6	-1.5	1.4	-1.8	-0.3	-0.4	1.2	-1.5	1.5	-0.8	-1.8
Arm fat-free mass (right)	1.4	7.4	25.6	-5.1	3.3	-4.3	-4.2	-3.3	-4.0	-3.1	-2.8	2.4	2.1	-1.6	0.1	0.4	-3.2	-2.7	-0.5	-1.9	-0.5	-1.8	-2.5	-1.0	2.2	-1.5	-2.8
Hypertension (Self-reported)	1.4	3.8	9.6	-1.7	1.6	-2.1	-2.4	-1.7	-2.4	-2.3	-2.0	2.1	-2.0	-1.9	-2.0	-2.1	-1.8	-2.0	1.4	-3.1	-1.5	-0.9	-0.9	-2.5	1.4	-1.5	-2.0
Medication for cholesterol	1.4	2.2	8.4	-2.5	0.1	0.1	0.4	-0.4	-0.3	-0.1	0.1	0.4	0.3	2.3	1.9	1.9	0.2	0.3	2.8	0.4	-0.5	1.1	2.1	2.6	2.9	2.0	-0.2
Osteoarthritis (self-reported)	1.4	1.9	4.2	1.3	-2.0	0.0	-0.5	2.0	1.3	0.9	1.7	-1.6	0.3	0.5	1.0	1.0	1.3	1.6	2.0	1.7	1.9	1.9	0.9	0.0	-1.2	1.4	1.3
Smoking status: Current	1.4	2.2	4.7	1.7	1.4	-1.6	-1.6	-1.3	-1.0	-1.2	-1.4	1.0	1.8	-1.9	-1.7	-1.7	-1.6	-1.5	-1.0	-1.1	-1.0	-1.9	-1.3	-2.2	-1.0	-1.8	-1.0
Arm fat-free mass (left)	1.4	7.1	27.2	-5.2	3.2	-4.2	-4.1	-3.1	-3.9	-3.0	-2.7	2.3	2.2	-1.6	0.2	0.5	-3.0	-2.5	-0.5	-2.0	-0.3	-1.9	-2.7	-1.0	1.8	-1.5	-2.8
Risk taking	1.4	2.0	4.2	0.9	-1.7	1.1	0.9	1.9	1.4	2.0	1.9	-1.8	-0.2	1.3	1.3	1.4	1.6	1.7	-0.7	1.4	1.9	1.3	0.7	0.8	-1.8	1.1	1.8
Medication for hormone replacement therapy	1.3	1.4	6.2	2.5	-1.1	1.2	1.0	1.4	1.4	1.5	1.1	-1.4	-0.3	-0.2	-0.3	-0.2	0.9	0.9	-2.0	1.1	0.6	0.4	-0.6	-0.6	-2.3	-0.2	1.3
Qualifications: A levels/AS levels or equivalent	1.3	2.9	6.3	-0.9	2.3	-0.9	-0.6	-2.4	-0.8	-2.0	-2.3	2.5	0.5	-0.9	-1.7	-1.6	-2.0	-2.3	1.0	-2.2	-0.1	-2.2	-1.6	-1.2	0.7	-1.8	-2.5
Length of working week for main job	1.3	1.5	5.3	-2.0	1.3	-1.9	-1.5	-1.2	-1.9	-1.5	-1.0	1.4	2.3	-0.4	0.3	0.2	-1.2	-0.9	0.9	-0.7	-0.8	-0.7	-0.7	-0.1	0.7	-0.4	-1.4
Medication: Atorvastatin	1.3	1.6	3.3	-0.2	0.7	-0.4	-0.4	-0.9	-1.4	-1.1	-1.0	1.5	-1.6	-1.7	-1.8	-1.8	-0.7	-1.1	-1.2	-1.8	-1.2	-1.2	-1.1	-1.5	-1.7	-1.3	-1.5
Basal metabolic rate	1.3	7.2	27.4	-5.2	3.3	-4.3	-4.1	-3.2	-3.8	-2.9	-2.7	2.3	2.4	-1.3	0.2	0.6	-3.0	-2.5	-0.3	-1.9	-0.1	-1.7	-2.5	-0.8	2.5	-1.5	-2.6
Severe depression (siblings)	1.2	1.4	3.6	-0.5	-1.4	1.2	0.8	1.4	1.9	1.3	1.4	-1.2	-0.2	1.2	1.1	1.3	1.3	1.4	-0.7	1.3	1.4	0.3	-1.8	0.7	-0.2	0.4	1.3
Pulse wave peak to peak time	1.2	1.4	3.5	-0.1	-0.7	1.0	1.3	0.9	1.0	1.0	1.1	-0.6	0.4	1.4	1.6	1.5	1.1	1.2	1.2	1.7	0.9	1.2	1.6	1.9	0.4	1.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.5	3.7	1.9	-1.4	1.8	1.7	1.4	1.9	1.3	1.3	-1.1	-0.4	0.8	0.3	-0.0	1.4	1.2	0.7	1.0	0.2	1.0	1.2	0.5	-1.6	1.0	1.1
Medication: Blood pressure	1.2	2.4	6.9	-0.5	1.0	-1.0	-1.5	-1.0	-1.3	-1.2	-1.3	0.8	-1.8	-2.3	-1.9	-1.8	-1.1	-1.3	-1.4	-2.1	-0.8	-1.3	-2.6	-2.6	-0.2	-1.9	-1.1
Ulcerative Colitis (UC)	1.1	2.2	12.7	-1.7	-1.1	1.2	0.9	1.3	0.5	1.6	1.3	-2.0	-3.6	1.8	1.2	1.4	1.4	1.3	-0.4	0.2	1.2	1.4	-0.1	1.1	1.4	1.4	1.9
Blood Platelet Count	1.1	13.2	29.6	4.0	3.5	-3.1	-4.0	-3.4	-3.3	-4.6	-4.0	4.4	0.7	-4.0	-4.8	-5.4	-4.2	-4.0	0.2	-3.5	-1.2	-3.2	0.8	-5.2	-0.4	-4.0	-3.8
Tanning	1.1	12.9	27.3	0.0	4.1	-5.2	-5.0	-4.1	-4.3	-4.5	-4.2	4.2	2.4	-4.3	-3.1	-3.4	-4.5	-4.2	0.8	-3.5	-1.9	-3.1	0.3	-3.6	0.8	-3.0	-4.1
Hand grip strength (right)	1.1	2.9	8.9	-1.4	-0.2	1.2	0.9	0.2	2.0	0.0	0.7	0.4	1.2	2.4	2.3	2.0	0.7	0.9	2.4	1.1	1.5	2.1	3.0	3.0	2.2	2.3	-0.4
Fed-up feelings	1.1	2.0	6.5	-1.2	-1.3	-0.1	-0.5	1.4	0.7	0.9	1.5	-1.3	1.7	1.3	2.5	2.5	1.0	1.6	0.8	2.4	0.8	1.4	0.5	1.3	1.2	1.2	1.5
Qualifications: CSEs or equivalent	1.1	1.4	3.7	-0.5	-0.5	0.6	0.9	0.9	0.9	0.9	1.1	-1.2	0.7	1.0	1.6	1.6	0.8	1.2	1.4	1.4	0.3	1.4	1.2	1.7	1.9	1.4	1.3
High blood pressure	1.1	3.1	8.4	-1.6	1.5	-1.9	-2.2	-1.6	-2.2	-2.2	-1.8	2.0	-1.8	-1.6	-1.7	-1.8	-1.6	-1.8	1.4	-2.9	-1.3	-0.7	-0.7	-2.2	1.3	-1.3	-2.0
Worry too long after embarrassment	1.1	1.8	4.6	0.2	-0.8	2.0	1.8	1.4	1.0	2.1	1.3	-1.9	-1.5	1.2	0.3	0.8	1.2	1.2	-2.0	0.8	1.9	-0.1	-1.7	0.3	-0.7	-0.1	1.7
Medication: Ibuprofen	1.1	1.3	2.4	-0.4	1.5	-1.3	-1.2	-1.6	-1.4	-1.1	-1.4	1.4	0.6	-0.3	-0.7	-0.5	-1.5	-1.4	0.7	-1.6	1.4	-0.8	-0.6	-1.0	0.9	-1.0	-1.3
Smoking status: Previous	1.1	1.7	5.2	1.6	1.2	-2.3	-2.2	-1.1	-1.6	-1.2	-1.3	1.0	1.9	-1.7	-0.8	-1.0	-1.5	-1.2	-0.2	-0.4	0.4	-0.8	-0.2	-1.7	-0.8	-1.1	-1.0
Medication: Paracetamol	1.1	1.7	3.7	0.5	-1.4	1.4	0.9	1.5	1.0	1.7	1.5	-1.9	-0.7	1.2	1.0	1.3	1.4	1.4	-1.6	1.6	1.7	0.9	-1.1	0.5	-0.6	0.7	1.8
Body Mass Index (BMI) (2010)	1.0	1.4	4.9	-0.4	1.5	-2.2	-1.8	-1.4	-1.2	-1.3	-1.3	1.5	1.3	-0.7	-0.8	-0.7	-1.7	-1.4	0.0	-0.9	-0.1	-1.3	-0.2	-0.9	0.6	-0.9	-1.4
Cardiovascular Disease	1.0	3.4	8.3	-0.3	1.7	-2.9	-2.6	-1.7	-2.3	-2.0	-1.9	1.8	-0.0	-2.1	-2.0	-1.9	-1.9	-2.0	0.5	-2.8	0.3	-1.2	-1.6	-2.7	0.1	-1.8	-1.8
Townsend deprivation index at recruitment	1.0	1.3	3.9	-0.2	1.2	-2.0	-1.5	-1.0	-1.7	-0.7	-1.1	0.7	1.2	-1.6	-0.7	-0.6	-1.3	-1.0	-1.5	-0.8	-1.2	-1.4	-1.0	-1.2	0.3	-1.1	-0.7
Hayfever, allergic rhinitis or eczema	1.0	2.2	6.8	1.5	-1.4	2.1	2.6	1.5	1.8	2.0	1.6	-1.9	-0.9	1.4	0.7	0.8	1.6	1.5	-0.2	1.5	0.9	1.5	0.9	1.4	-1.1	1.0	1.6
Exposure to tobacco smoke outside home	1.0	1.3	3.4	-0.3	-1.2	0.1	-0.4	1.5	0.7	0.6	1.5	-1.2	-0.2	0.8	1.8	1.6	1.0	1.6	1.3	1.6	0.6	1.7	0.9	1.1	0.9	1.4	1.3
Neck or shoulder pain in last month	1.0	1.4	3.8	0.9	-1.6	0.7	1.0	1.7	1.1	1.3	1.5	-1.7	-2.0	-0.1	0.6	0.7	1.4	1.4	0.3	1.2	0.9	0.8	-0.9	0.2	-1.6	0.7	1.4
Overall health rating	1.0	2.1	6.3	0.4	-2.1	1.3	1.1	2.1	1.2	2.0	2.0	-2.0	-0.1	0.7	1.2	1.3	1.8	1.9	-0.1	2.5	1.1	0.9	0.2	0.7	-0.7	0.7	2.1
High cholesterol (Self-reported)	1.0	1.8	5.9	-1.1	1.2	-1.8	-2.1	-1.2	-2.4	-1.5	-1.4	1.2	-1.4	-1.5	-1.3	-1.4	-1.3	-1.4	0.1	-1.5	-0.5	-0.4	0.2	-1.6	0.4	-1.1	-1.4
Irritable Bowel Disease (IBD)	0.9	2.0	11.1	-1.8	-1.1	1.6	1.0	1.2	0.9	1.5	1.3	-1.5	-3.3	1.5	1.1	1.3	1.4	1.3	-0.9	0.4	0.9	1.4	0.3	1.3	1.5	1.5	1.7
Current tobacco smoking	0.9	1.4	3.4	1.8	0.9	-1.2	-1.2	-0.9	-0.7	-0.6	-1.0	0.4	1.3	-1.8	-1.4	-1.4	-1.2	-1.1	-1.3	-0.7	-0.7	-1.6	-1.1	-1.8	-1.1	-1.4	-0.5
Average weekly fortified wine intake	0.9	1.1	3.9	-2.0	-0.1	0.1	0.4	0.2	0.9	-0.3	0.5	0.3	0.6	1.6	1.6	1.4	0.5	0.6	1.8	0.4	0.9	1.0	1.0	1.8	1.1	1.2	-0.2
Hair/balding pattern: Pattern 2	0.9	1.1	9.7	-0.6	0.3	-1.2	-1.3	-0.4	-0.4	-1.1	-0.3	1.1	2.1	0.7	1.1	0.8	-0.5	-0.1	3.1	-0.1	0.7	0.4	1.0	0.4	0.3	0.7	-1.1
Heart attack	0.9	1.2	5.0	0.6	0.7	-1.4	-1.5	-0.6	-0.1	-1.5	-0.8	1.6	1.4	-0.3	-1.1	-1.5	-0.8	-0.8	2.2	-0.7	-0.2	-0.8	1.4	-1.0	0.2	-0.8	-1.1
Weight	0.9	4.5	16.0	-4.0	2.4	-3.9	-3.7	-2.2	-2.9	-2.4	-2.0	1.5	2.4	-0.8	0.3	0.5	-2.4	-1.8	0.9	-1.4	0.2	-0.9	-1.8	-0.8	2.3	-0.9	-1.8
Falls in the last year	0.9	1.2	8.6	2.3	-0.4	0.7	0.9	0.7	-0.0	1.2	0.5	-1.4	-0.6	-1.1	-0.8	-0.6	0.3	0.3	-2.9	0.6	0.6	-0.3	-0.8	-1.1	-1.4	-0.8	1.1
Medication: Lansoprazole	0.9	1.0	3.3	0.3	-1.4	1.6	1.3	1.1	1.5	1.2	1.1	-0.9	-0.5	1.0	0.5	0.7	1.2	1.0	-0.6	1.0	1.8	0.6	-0.7	0.3	-0.8	0.4	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.9	-0.9	-0.7	0.8	1.6	0.7	0.6	1.0	0.9	-0.6	-1.1	1.5	1.1	1.1	1.2	1.0	1.0	-0.1	1.4	1.1	1.0	1.7	0.3	1.3	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.3	0.3	1.3	-1.1	-1.1	-1.1	-0.7	-1.0	-1.2	1.1	0.0	-0.9	-1.4	-1.5	-1.3	-1.3	-0.5	-1.4	-1.0	-0.9	-0.1	-1.3	0.4	-1.4	-0.8
Commuting to job workplace: Walk	0.9	1.0	5.4	2.3	-0.9	1.2	1.2	1.0	0.6	0.9	0.7	-1.2	-0.9	-0.5	-0.6	-0.7	0.8	0.6	-1.4	0.6	-0.6	-0.3	-0.6	-0.6	-1.9	-0.2	1.2
Medication: Aspirin	0.9	1.1	4.8	0.6	-1.0	0.5	-0.1	1.2	1.1	0.8	1.0	-0.9	-2.2	1.3	0.3	0.3	0.7	0.9	1.2	-0.1	1.3	1.8	1.6	0.0	1.1	1.2	1.1
Irritability	0.9	1.5	5.9	-1.5	1.1	-2.1	-2.4	-1.1	-1.0	-1.4	-0.9	1.0	1.3	0.5	0.7	0.7	-1.3	-0.8	2.1	-0.6	0.4	0.3	-0.2	-0.2	2.4	0.1	-1.0
Diastolic blood pressure, automated reading	0.9	2.8	7.7	-0.4	-2.0	2.2	2.1	2.3	1.0	2.4	2.1	-2.8	-1.5	1.2	1.2	1.3	2.1	2.0	-0.7	1.5	0.3	1.5	-0.9	0.6	-0.3	0.8	2.6
Alzheimer’s Disease (in father)	0.8	0.9	8.5	-2.9	0.9	-0.7	-0.3	-0.7	-1.1	-1.1	-0.5	1.0	0.2	-0.1	0.1	0.0	-0.5	-0.4	0.7	-0.9	-1.8	-0.2	-0.2	0.6	0.7	0.1	-1.2
Ovarian Cancer	0.8	1.1	2.6	1.0	-1.2	1.0	1.3	1.3	1.6	1.2	1.3	-1.1	0.9	0.6	0.8	0.7	1.2	1.3	0.3	1.4	1.0	0.5	-1.1	0.5	-1.2	0.4	1.0
Type 2 Diabetes (T2D) (2018)	0.8	1.4	5.4	2.3	0.7	-1.6	-1.2	-0.7	-0.9	-1.2	-1.0	0.9	1.5	-1.5	-1.3	-1.5	-1.1	-0.9	0.1	-0.7	0.1	-0.3	0.2	-1.9	-1.7	-1.1	-1.0
Hearing difficulty/problems: Yes	0.8	1.2	9.5	-0.1	0.0	-0.5	-0.5	0.0	-0.8	0.1	-0.1	-0.2	0.4	-1.5	-0.7	-0.5	-0.1	-0.1	-3.1	0.6	-1.4	-1.5	-2.1	-0.8	-2.1	-1.3	0.0
Medication: Co-codamol	0.8	0.9	6.1	1.8	-0.9	0.6	0.0	1.0	0.8	0.3	0.8	-0.5	1.7	-0.9	-0.1	-0.2	0.6	0.8	-0.6	1.2	-0.3	-0.3	-1.0	-0.5	-2.5	-0.4	0.5
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	3.7	0.1	-0.9	0.4	0.6	1.0	0.2	1.2	1.0	-1.3	-1.9	-0.2	0.8	0.8	0.8	0.9	-0.8	0.7	0.5	0.8	1.1	0.7	-0.2	0.6	1.4
Medication: Levothyroxine sodium	0.8	1.3	6.6	-0.9	0.9	-1.2	-1.2	-0.7	-0.7	-1.9	-0.8	1.7	0.4	-0.9	-0.4	-0.9	-0.9	-0.7	2.2	-0.7	-2.6	-0.4	1.0	-0.1	-0.3	0.3	-1.7
Hearing difficulty/problems with background noise	0.8	1.3	3.4	-1.0	-1.1	1.2	1.2	1.3	0.5	1.6	1.4	-1.8	-1.2	0.4	0.9	1.1	1.2	1.3	-1.8	1.2	-0.2	0.4	-0.9	1.1	-0.7	0.6	1.6
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.3	0.0	-1.0	1.5	0.9	1.1	1.4	1.1	1.1	-0.9	-0.2	0.9	0.7	1.1	0.9	1.0	-0.8	0.9	1.2	0.3	-0.7	0.9	-0.8	0.6	0.7
Arm fat mass (right)	0.8	3.1	10.9	-2.5	1.9	-3.3	-3.1	-1.7	-2.4	-2.0	-1.7	1.2	2.1	-1.0	-0.4	-0.4	-2.0	-1.6	1.8	-1.6	-0.2	-0.6	-1.6	-1.4	1.2	-1.1	-1.5
Chronic bronchitis/emphysema (mother)	0.8	0.9	2.2	-1.5	-1.3	0.3	0.4	1.1	0.7	0.8	1.2	-0.8	-0.2	0.4	1.4	1.4	1.3	1.3	-0.3	1.0	-0.8	0.9	-0.1	1.3	0.3	1.2	0.9
Number of children fathered	0.8	0.9	5.1	1.9	0.3	-1.3	-1.7	-0.4	0.4	-0.6	-0.4	0.1	2.3	0.1	-0.0	-0.1	-0.6	-0.4	2.0	0.5	1.3	-0.1	0.3	-0.6	-0.4	-0.4	-0.3
Age at first live birth	0.8	1.4	3.3	-1.5	1.5	-0.6	-0.5	-1.5	-0.9	-1.6	-1.4	1.7	-0.6	-0.8	-1.0	-1.1	-1.2	-1.4	1.0	-1.6	-1.2	-1.3	-0.8	-0.3	0.1	-1.0	-1.8
Shortness of breath walking on level ground	0.8	0.9	2.5	0.2	-0.7	-0.9	-1.1	0.8	-0.2	0.8	0.8	-1.4	0.3	0.0	1.4	1.5	0.4	0.8	-1.3	1.5	0.4	1.3	0.7	0.3	1.0	0.8	1.6
Medication: Seretide 50 evohaler	0.8	0.9	2.3	-0.9	1.2	-0.7	-0.7	-1.0	-1.3	-0.6	-1.0	0.5	-1.3	-0.6	-1.0	-0.9	-1.1	-1.0	-0.4	-1.5	-0.8	-1.0	-1.4	-0.9	-0.0	-1.2	-0.7
Alcohol intake frequency.	0.8	1.8	4.5	1.3	-1.7	1.5	1.3	1.6	1.3	1.9	1.5	-2.0	-0.4	0.7	0.9	1.0	1.5	1.5	-0.3	2.1	0.4	1.1	0.8	0.8	-0.6	1.0	2.0
Average weekly red wine intake	0.8	1.1	8.2	1.5	0.4	-0.5	-0.6	-0.3	0.7	-0.5	-0.2	0.2	2.9	1.3	0.8	0.7	-0.4	-0.1	2.0	0.3	2.3	0.8	0.8	0.2	0.5	0.5	-0.6
Loneliness, isolation	0.8	1.1	5.9	-2.4	-0.4	-0.7	-0.3	0.4	-0.1	0.2	0.7	-0.4	0.6	1.1	2.0	2.0	0.4	0.8	0.6	1.0	0.2	0.8	0.0	1.7	1.2	1.3	0.5
Arm fat mass (left)	0.8	3.2	11.3	-2.6	1.9	-3.4	-3.2	-1.7	-2.4	-2.1	-1.7	1.2	2.0	-0.8	-0.4	-0.4	-2.1	-1.6	1.8	-1.6	-0.2	-0.5	-1.4	-1.4	1.4	-1.0	-1.5
Vascular/heart problems diagnosed by doctor	0.8	2.1	5.8	1.2	-1.1	1.7	2.0	1.1	1.5	1.9	1.4	-1.6	1.0	1.1	1.3	1.4	1.2	1.3	-2.1	2.4	0.8	0.5	0.5	1.9	-1.2	0.9	1.6
Angina	0.7	0.9	1.9	-0.3	1.0	-0.7	-0.8	-1.2	-1.0	-1.0	-1.1	1.4	1.0	-0.8	-0.7	-0.8	-1.0	-1.1	0.7	-1.2	-0.9	-1.3	-0.8	-0.9	0.0	-0.9	-1.2
Medication: Metformin	0.7	1.0	2.4	-0.3	1.0	-1.5	-1.4	-1.1	-1.3	-1.4	-1.1	1.3	0.7	-1.0	-0.7	-0.7	-1.2	-1.1	-0.1	-1.1	-0.6	-0.5	-0.2	-1.1	-0.4	-0.8	-1.2
Forced vital capacity (FVC)	0.7	2.6	5.7	-2.0	-1.4	1.8	1.8	1.2	1.0	1.8	1.5	-1.6	-2.2	1.5	2.0	2.4	1.8	1.6	-1.2	1.5	0.9	0.9	0.1	2.1	1.3	1.5	1.7
Time employed in main current job	0.7	0.8	2.5	0.2	0.9	0.2	0.2	-0.8	-1.2	-0.2	-0.9	0.6	0.0	-0.4	-1.6	-1.4	-0.7	-0.9	-0.4	-1.4	0.6	-1.1	-1.2	-1.2	0.0	-1.4	-0.7
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.6	0.1	-0.9	1.0	1.1	0.9	0.7	1.1	1.0	-0.8	-0.4	1.0	1.0	1.0	1.2	1.0	0.1	1.3	0.5	1.2	1.3	1.1	0.5	1.2	0.8
Leg fat mass (right)	0.7	2.6	10.8	-1.4	1.6	-3.3	-3.3	-1.4	-2.0	-2.0	-1.5	1.1	2.2	-0.9	-0.6	-0.6	-1.9	-1.4	1.9	-1.0	0.3	-0.4	-1.2	-1.6	0.8	-1.0	-1.3
Number of full sisters	0.7	0.9	2.0	-0.0	1.2	-1.2	-1.2	-1.3	-0.7	-0.8	-1.2	0.4	0.9	-0.4	-0.6	-0.5	-1.2	-1.1	-0.7	-0.9	-0.7	-1.3	-1.3	-0.8	1.4	-0.8	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.8	-0.9	1.0	0.3	0.7	-1.3	-0.6	-0.3	-1.1	1.0	0.4	-0.2	-0.9	-0.6	-0.6	-1.1	-1.1	-0.9	-0.5	-1.2	-1.7	-0.4	-0.1	-1.2	-1.2
Qualifications: nursing, teaching	0.7	1.0	3.7	0.2	0.9	-0.4	-0.3	-1.0	0.5	-0.9	-0.9	1.3	1.9	-0.2	-0.8	-0.6	-0.9	-1.0	1.2	-1.6	1.1	-1.1	-1.5	-0.7	-0.6	-1.0	-1.4
Miserableness	0.7	1.2	6.3	-2.5	1.0	-1.5	-2.1	-0.9	-2.0	-1.2	-0.8	0.7	-0.4	-0.5	0.5	0.6	-1.3	-0.7	0.1	-0.5	-1.0	-0.3	-1.1	-0.2	1.3	-0.4	-0.7
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.6	1.8	-1.2	0.6	0.7	1.1	1.0	1.2	0.9	-1.3	-0.2	0.2	-0.3	-0.1	0.7	0.7	0.4	0.8	1.9	0.6	-0.8	-0.8	-1.2	-0.2	1.2
Fasting Glucose	0.6	0.7	3.5	1.9	-0.4	0.9	0.7	0.7	0.3	0.9	0.5	-1.2	-1.2	1.1	-0.1	-0.2	0.3	0.4	0.1	0.7	1.6	0.3	0.6	-0.3	-0.5	0.3	1.0
Number of treatments/medications taken	0.6	1.1	5.0	0.6	0.8	-1.0	-1.4	-0.6	-1.1	-0.8	-0.9	0.8	0.1	-0.8	-1.3	-1.2	-1.1	-0.9	0.2	-1.2	0.7	-0.8	-1.2	-2.2	-0.9	-1.5	-0.8
Ever had hysterectomy (womb removed)	0.6	0.7	5.1	2.3	-0.5	0.2	0.2	0.5	0.4	0.7	0.2	-1.0	-0.2	-0.1	-0.9	-0.6	0.2	0.1	-0.9	0.6	1.4	-0.3	-1.0	-1.1	-1.3	-0.7	0.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	3.5	-0.0	0.6	-0.5	-0.4	-0.5	-1.0	-0.4	-0.5	0.6	0.1	-0.7	-0.7	-0.6	-0.6	-0.6	-1.9	-0.5	-0.8	-1.3	-1.4	-0.9	-1.1	-1.1	-0.6
Maternal smoking around birth	0.6	0.9	2.7	0.3	-1.4	1.0	1.1	1.4	1.0	1.3	1.3	-1.5	-0.1	0.1	0.4	0.4	1.3	1.2	-0.6	1.0	-0.9	0.4	0.0	0.4	-0.4	0.6	1.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.8	4.0	1.7	-0.8	0.8	0.7	0.6	1.2	0.8	0.5	-0.6	0.6	-0.4	-0.5	-0.4	0.5	0.4	-1.6	0.7	0.4	-0.9	-0.4	-0.3	-2.0	-0.6	0.7
Financial difficulties in last 2 years	0.6	0.8	5.4	1.4	-0.6	0.3	0.5	0.8	0.9	0.8	0.8	-0.7	1.8	-0.4	0.6	0.6	0.5	0.8	-0.4	1.1	0.2	-0.3	-1.3	-0.0	-2.3	-0.0	0.6
Mouth/teeth dental problems	0.6	0.9	4.0	-0.7	1.0	-0.5	-0.8	-1.0	-0.5	-1.2	-1.0	1.3	0.3	-0.3	-0.7	-0.8	-1.0	-1.0	1.2	-2.0	0.7	-0.8	-0.8	-1.0	-0.2	-0.9	-1.5
Noisy workplace	0.6	0.8	2.5	-0.1	1.0	-1.0	-1.0	-0.9	-0.8	-1.1	-1.0	0.9	-0.5	-1.0	-1.0	-1.1	-1.0	-1.0	-0.6	-1.0	-1.6	-0.4	-0.2	-0.8	0.2	-0.7	-0.8
Pulse wave Arterial Stiffness index	0.6	0.8	2.0	-0.1	0.5	-0.8	-1.0	-0.7	-0.7	-0.8	-0.8	0.3	-0.4	-0.9	-1.1	-1.0	-0.8	-0.9	-1.1	-1.3	-0.5	-0.9	-1.4	-1.3	-0.1	-1.1	-0.4
Hair/balding pattern: Pattern 4	0.6	1.3	6.0	1.0	0.8	-2.3	-2.5	-1.0	-0.3	-1.7	-1.0	1.0	1.6	-1.3	-0.6	-0.7	-1.4	-1.1	1.0	-1.0	0.3	-0.4	0.0	-1.2	0.4	-0.8	-0.9
Forced vital capacity (FVC), Best measure	0.6	2.1	5.2	-2.3	-1.0	1.9	1.9	0.9	0.6	1.7	1.2	-1.3	-2.3	1.2	1.8	2.2	1.5	1.2	-1.6	1.0	0.8	0.5	-0.7	1.8	1.0	1.1	1.3
Medication: Omeprazole	0.6	0.7	5.8	0.8	-0.7	0.1	-0.3	0.4	-0.1	0.7	0.4	-0.5	0.2	-0.7	-0.2	0.2	0.2	0.3	-1.5	0.8	0.7	-0.6	-1.5	-0.8	-2.4	-0.8	0.3
Had major operations	0.6	0.7	3.8	0.3	0.3	-0.2	-0.1	-0.0	-0.2	-0.6	-0.2	0.5	-0.7	-2.0	-0.8	-0.9	-0.3	-0.3	-0.8	-1.4	-1.8	-0.5	-1.0	-0.8	-1.5	-0.5	-0.7
Medication: Aspirin	0.6	0.7	3.5	0.5	-0.7	0.3	-0.2	0.9	0.8	0.6	0.7	-0.6	-1.9	0.9	-0.1	-0.0	0.5	0.6	1.0	-0.3	1.3	1.5	1.5	-0.2	0.9	0.9	0.7
Long-standing illness, disability or infirmity	0.6	1.0	4.7	1.1	0.2	-0.6	-0.4	0.1	-0.4	0.3	-0.1	-0.4	0.5	-0.8	-0.6	-0.6	-0.4	-0.2	-1.5	-0.3	1.0	-1.2	-2.2	-1.7	-2.1	-1.4	0.4
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.2	-0.7	0.9	-1.3	-0.6	-1.0	-1.3	-0.2	-1.0	-0.1	-0.7	-0.8	-0.9	-0.6	-1.0	-1.1	-1.8	-0.4	-1.2	-0.9	-1.8	-0.5	0.9	-0.8	-0.0
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.1	-1.5	0.7	-0.5	-0.6	-0.5	-0.5	-0.6	-0.4	0.9	-1.4	0.8	0.2	0.2	-0.4	-0.4	1.4	-1.3	0.6	0.6	1.2	0.3	1.1	0.5	-0.9
Unable to work because of sickness or disability	0.6	0.8	3.5	0.1	0.2	0.9	0.9	-0.1	-0.3	0.4	-0.2	-0.2	-1.2	-0.8	-0.8	-0.9	-0.1	-0.2	-1.6	-0.9	-1.4	-1.0	-1.9	-0.8	-1.1	-1.1	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	6.2	0.1	-0.8	0.5	0.0	0.5	-0.1	0.7	0.4	-0.5	-0.7	-0.7	-0.2	0.2	0.4	0.3	-1.6	0.5	0.5	-0.5	-1.9	-0.8	-2.5	-0.7	0.2
Heart attack/myocardial infarction (self-reported)	0.6	0.8	4.8	0.7	0.3	-1.0	-1.2	-0.3	0.2	-1.1	-0.4	1.2	1.1	-0.1	-0.9	-1.3	-0.5	-0.5	2.2	-0.4	0.0	-0.6	1.3	-0.9	0.0	-0.6	-0.7
Leg fat mass (left)	0.6	2.5	10.6	-1.6	1.5	-3.2	-3.3	-1.3	-2.0	-1.9	-1.4	0.9	2.0	-0.8	-0.5	-0.5	-1.9	-1.4	1.9	-1.1	0.3	-0.3	-1.3	-1.6	0.9	-0.9	-1.2
Blood White Count	0.5	3.6	28.5	5.3	-1.3	1.3	1.6	1.5	1.7	1.8	1.0	-1.8	2.6	-0.5	-1.1	-1.2	1.0	0.9	-1.5	1.8	1.5	-0.4	-0.6	-1.8	-3.6	-1.2	1.7
Chronotype (morning person)	0.5	1.2	9.4	1.4	-0.2	-1.8	-2.1	0.0	-0.7	0.1	-0.3	-0.7	0.5	0.3	-0.8	-0.6	-0.4	-0.3	1.2	0.5	3.1	-0.3	0.6	-1.7	1.0	-0.7	0.7
Diabetes (mother)	0.5	0.6	1.5	0.9	-0.9	0.9	1.2	1.0	1.1	1.0	1.0	-0.7	-0.2	0.7	0.3	0.3	1.0	0.9	0.5	0.6	0.5	0.7	0.3	0.6	-1.2	0.7	0.6
Trunk fat percentage	0.5	2.2	6.6	-0.5	-1.3	0.1	0.4	1.5	1.5	1.2	1.5	-1.6	0.2	2.1	1.7	1.5	1.3	1.5	2.6	1.2	1.6	2.2	1.0	1.4	1.2	1.8	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	4.8	-1.8	-0.1	0.7	0.7	-0.0	-0.4	1.0	0.2	-0.4	-0.3	-0.0	0.5	0.9	0.4	0.2	-2.2	0.7	-0.3	-0.9	-1.8	0.5	-0.2	-0.6	0.3
Qualifications: None of the above	0.5	1.0	6.6	-1.0	0.3	-2.2	-2.6	-0.3	-2.2	-0.7	-0.3	0.0	-0.2	-0.8	0.6	0.5	-0.7	-0.2	0.4	0.2	-0.8	0.6	1.1	-0.1	1.6	0.3	0.2
Arm fat percentage (right)	0.5	1.8	6.2	-1.2	1.3	-2.5	-2.3	-1.1	-1.6	-1.5	-1.1	0.8	1.9	-0.6	-0.5	-0.6	-1.5	-1.1	2.4	-1.5	-0.1	-0.1	-0.9	-1.3	0.7	-0.7	-0.9
Hair/balding pattern: Pattern 3	0.5	0.7	1.7	0.5	1.0	-0.9	-0.8	-0.7	-0.6	-0.5	-0.9	0.5	0.4	-1.0	-1.3	-1.3	-0.8	-0.9	-0.9	-0.9	0.4	-1.2	-0.5	-1.2	-0.0	-1.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	4.1	-0.8	1.0	-0.7	-0.6	-1.0	-0.9	-0.3	-0.8	0.7	0.7	0.3	0.0	0.3	-0.9	-0.8	0.3	-0.9	2.0	-0.3	-0.3	-0.2	1.5	-0.3	-0.5
Loud music exposure frequency	0.5	0.5	5.3	-0.6	-0.4	1.1	0.7	0.3	0.3	0.6	0.3	-0.3	-2.3	0.4	-0.3	-0.2	0.6	0.3	-1.0	0.1	-1.0	0.5	-0.2	0.2	0.7	0.3	0.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	5.7	-1.5	-0.1	0.8	1.6	-0.1	1.2	0.1	0.2	0.1	-0.2	0.8	0.7	0.8	0.5	0.2	2.4	-0.1	0.5	0.5	-0.5	1.2	1.0	0.8	-0.4
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.4	1.5	-0.7	1.2	0.7	0.7	1.2	0.8	0.6	-0.9	1.2	0.5	0.1	0.1	0.5	0.6	0.2	0.8	1.3	0.6	0.1	-0.3	-0.7	0.1	0.6
Birth weight	0.5	1.2	10.8	-3.3	0.8	-0.6	-0.7	-0.9	-0.7	-0.2	-0.5	0.1	-0.5	0.3	0.9	1.4	-0.4	-0.4	-1.4	-0.4	0.6	-0.7	-1.7	1.1	2.1	0.0	-0.1
Qualifications: College or University degree	0.5	1.5	5.2	-0.5	-0.8	1.9	2.3	0.7	2.2	1.4	1.0	-0.4	0.1	1.4	1.0	1.3	1.2	1.0	-1.0	0.2	0.7	0.1	-1.5	1.5	-1.7	0.7	0.1
Emphysema/chronic bronchitis	0.5	0.6	3.5	-1.2	-0.1	0.5	0.5	0.2	-0.4	0.1	0.2	0.1	-1.9	-0.4	-0.1	-0.2	0.4	0.3	-1.6	0.5	-1.6	0.3	0.9	0.6	1.0	0.3	0.1
Angina (self-reported)	0.5	0.7	1.4	-0.2	0.8	-0.6	-0.8	-0.9	-0.8	-0.9	-0.9	1.2	1.1	-0.6	-0.6	-0.7	-0.9	-0.9	0.8	-0.9	-0.8	-1.1	-0.5	-0.9	-0.0	-0.8	-1.0
Knee pain experienced in last month	0.5	0.8	3.4	1.9	-1.1	-0.4	-0.3	1.3	0.7	0.4	1.0	-1.0	-0.3	-0.2	-0.1	-0.3	0.6	0.9	0.6	0.6	1.7	0.9	0.4	-0.7	-0.8	0.2	1.1
Illnesses of father: None of the above (group 1)	0.5	0.7	4.2	1.2	-0.3	0.8	1.1	0.2	0.4	1.1	0.3	-1.0	0.2	0.4	-0.0	0.2	0.2	0.3	-1.8	0.6	2.1	0.1	-0.0	0.3	-1.0	0.1	0.9
Ever taken oral contraceptive pill	0.5	0.6	3.3	-0.4	0.5	-1.7	-1.8	-0.7	-0.9	-0.6	-0.6	0.3	0.3	-0.0	-0.3	-0.1	-0.8	-0.6	-0.5	-0.7	0.9	-0.5	-1.0	-0.7	-0.1	-0.7	-0.3
Commuting to job workplace: Public transport	0.5	0.7	3.9	0.6	-0.8	0.4	0.5	0.8	1.0	0.7	0.8	-0.6	2.0	0.9	0.7	0.7	0.7	0.8	-0.5	1.1	1.1	0.2	0.3	0.5	-0.8	0.3	0.7
Crohns Disease (2012)	0.4	0.6	1.6	-0.3	-0.7	1.1	1.1	0.7	1.3	1.0	0.8	-0.5	-0.8	0.2	0.8	0.9	0.9	0.7	-0.7	0.4	0.3	0.6	0.3	0.9	0.4	1.0	0.7
Mean Putamen Volume	0.4	0.5	3.0	-0.1	-0.4	1.3	1.7	0.3	0.4	0.8	0.5	-0.3	0.4	-0.6	0.5	0.5	0.7	0.5	-1.1	0.5	-0.1	-0.0	-0.8	0.8	-0.1	0.4	0.2
Heel T-Score	0.4	2.8	19.4	1.1	-0.4	-2.1	-1.3	0.3	-1.4	-1.3	-0.0	1.8	2.1	-2.1	-1.3	-1.8	-0.4	-0.2	1.1	0.4	-3.0	-0.7	2.0	-1.3	-4.4	-0.9	-1.5
Allergy or Eczema	0.4	1.0	3.7	1.5	-0.8	1.1	1.9	0.9	1.3	1.1	0.8	-1.0	-0.2	1.0	0.2	0.1	1.0	0.8	0.8	1.0	0.6	1.1	1.5	1.0	-0.5	0.8	0.9
Hypothyroidism (self reported)	0.4	0.9	8.0	0.4	0.1	-0.3	-0.3	-0.1	0.2	-1.1	-0.1	1.0	0.9	-0.2	0.1	-0.5	-0.2	-0.1	2.8	0.1	-1.8	0.7	1.7	0.1	-0.9	0.8	-1.1
Relative age of first facial hair	0.4	0.8	3.1	-0.9	0.6	-0.2	-0.3	-0.6	-1.1	-0.8	-0.6	0.8	-1.4	-1.3	-0.6	-0.6	-0.6	-0.5	-1.8	-0.6	-1.7	-0.5	-0.7	-0.3	-0.5	-0.6	-1.0
Supplements: Zinc	0.4	0.4	3.4	-0.8	-0.1	-0.0	-0.1	-0.1	-0.5	0.1	-0.2	-0.1	-0.3	-0.5	-0.3	-0.1	-0.1	-0.2	-1.4	-0.1	-1.3	-0.7	-1.8	-0.7	-1.0	-0.6	-0.1
Taking other prescription medications	0.4	0.6	3.0	-0.0	-1.2	0.3	0.2	1.2	0.8	0.7	1.1	-0.3	0.5	0.4	0.7	0.7	0.9	1.1	1.0	1.0	0.4	0.4	0.1	0.1	-1.7	0.5	0.5
Medication: Ramipril	0.4	0.6	1.5	-0.5	0.7	-1.2	-1.0	-0.5	-0.7	-1.0	-0.5	1.1	0.9	-0.7	-0.4	-0.6	-0.6	-0.5	0.1	-0.8	-1.1	-0.8	0.2	-0.6	-0.7	-0.5	-0.9
Medication: Simvastatin	0.4	0.6	3.0	-0.7	0.5	-0.9	-0.9	-0.4	-0.6	-0.5	-0.5	0.4	-0.9	0.2	-0.4	-0.5	-0.5	-0.4	1.0	-0.9	1.1	0.8	1.3	-0.5	1.7	0.0	-0.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	7.0	-0.2	0.5	-0.8	-0.9	-0.2	-0.2	-1.4	-0.3	1.1	0.6	-0.4	-0.0	-0.5	-0.5	-0.2	2.6	0.0	-1.8	0.4	1.4	0.2	-0.5	0.7	-1.2
Leg fat percentage (right)	0.4	1.3	5.4	1.0	0.6	-2.1	-2.2	-0.3	-0.7	-1.2	-0.6	0.4	1.8	-0.9	-1.0	-1.3	-1.1	-0.7	2.3	-0.4	0.3	0.2	-0.2	-1.9	-0.4	-0.7	-0.5
Age at last live birth	0.4	0.5	1.7	-1.2	0.7	-0.3	-0.2	-0.9	-0.6	-0.8	-0.8	1.1	-0.2	-0.8	-0.5	-0.5	-0.4	-0.7	0.5	-0.8	-1.3	-0.9	-0.5	-0.1	-0.2	-0.5	-1.1
Arm fat percentage (left)	0.4	1.4	6.1	-1.3	1.1	-2.3	-2.1	-0.8	-1.4	-1.3	-0.9	0.6	1.6	-0.4	-0.4	-0.5	-1.3	-0.9	2.5	-1.2	-0.2	0.2	-0.6	-1.0	0.9	-0.4	-0.7
Breast cancer (self-reported)	0.4	0.5	1.8	0.7	-0.8	1.0	0.8	0.6	1.3	0.7	0.5	-0.9	-1.3	0.5	-0.1	-0.0	0.6	0.5	-0.6	0.2	0.9	0.5	-0.0	-0.2	0.4	0.1	0.9
Mother’s age at death	0.4	0.5	2.1	-0.3	-0.1	0.3	0.6	0.4	0.4	-0.2	0.4	0.0	-1.4	0.4	0.7	0.5	0.5	0.5	0.3	0.4	-1.3	0.9	0.7	1.3	0.9	0.9	0.0
Age started oral contraceptive pill	0.4	0.5	2.7	-1.6	0.1	-0.6	-0.8	-0.4	-0.3	-1.1	-0.2	1.1	0.8	-0.3	0.7	0.6	-0.2	-0.1	0.3	-0.4	-0.7	-0.1	-0.5	0.4	-1.0	0.2	-1.1
Heart disease (siblings)	0.4	0.5	1.8	0.2	-0.8	0.1	-0.5	0.7	0.5	0.5	0.7	-0.5	-0.2	0.7	0.7	0.6	0.5	0.7	-0.3	0.8	1.3	0.9	1.2	0.5	0.7	0.8	0.8
Schizophrenia vs Biploar Disorder	0.3	0.4	2.5	-0.7	-0.3	-0.3	-0.7	0.1	-0.8	-0.8	0.1	0.7	-0.0	-0.4	0.4	0.1	0.0	0.2	1.1	0.7	-1.6	0.5	1.1	0.1	-0.2	0.6	-0.7
Alzheimer’s Disease (including proxy)	0.3	0.5	3.8	-2.0	0.6	-0.2	0.3	-0.1	0.0	-0.2	0.0	0.1	-0.8	0.5	0.4	0.4	0.0	0.1	1.4	-0.7	-0.2	0.4	0.4	1.0	1.4	0.7	-0.2
Reaction Time	0.3	0.5	2.4	-0.6	-0.6	-0.5	-0.6	0.6	0.6	0.2	0.6	-0.6	-0.6	0.3	0.9	0.7	0.5	0.7	0.5	-0.5	-0.6	0.9	0.1	0.6	1.5	1.0	0.9
HbA1C	0.3	0.4	1.6	-0.8	-0.7	-0.6	-0.5	0.6	-0.6	0.2	0.5	-0.4	-1.1	-0.1	0.6	0.5	0.5	0.6	0.3	0.4	-0.7	0.8	1.3	0.4	-0.3	0.8	0.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.2	-0.4	-0.3	1.0	1.0	0.6	0.7	0.5	0.6	-0.4	0.5	0.1	0.4	0.3	0.4	0.6	-0.9	0.4	-0.6	-0.5	-0.7	0.5	-1.1	0.0	0.5
Supplements: Glucosamine	0.3	0.4	2.3	0.5	0.1	-0.8	-1.0	-0.1	-0.7	-0.4	-0.2	-0.0	0.7	-1.2	-0.2	-0.2	-0.4	-0.2	-0.2	0.0	-0.1	-0.6	-1.2	-1.0	-1.5	-0.8	-0.1
Medication: Atenolol	0.3	0.4	2.4	1.0	0.1	-0.3	-0.4	-0.1	0.2	-0.5	-0.3	0.7	0.2	-0.3	-0.9	-1.2	-0.3	-0.4	1.5	-0.9	-0.3	-0.1	0.8	-1.1	-0.1	-0.4	-0.3
Trunk fat mass	0.3	1.2	4.9	-2.1	-0.0	-1.2	-0.9	0.2	0.1	0.0	0.4	-0.6	1.1	1.4	1.5	1.5	0.1	0.5	2.2	0.4	1.4	1.3	0.0	1.0	1.9	1.1	0.5
Had menopause	0.3	0.3	1.3	-0.0	0.2	-0.1	-0.5	-0.3	-0.5	-0.5	-0.5	0.4	-0.6	-1.0	-0.8	-0.9	-0.4	-0.5	-0.5	-0.7	-0.9	-0.5	-0.2	-1.2	-0.3	-0.4	-0.4
Had other major operations	0.3	0.4	3.5	1.0	-0.3	0.3	0.4	0.5	1.1	0.6	0.4	-0.7	0.5	0.2	0.2	0.4	0.3	0.4	-0.1	-0.4	1.9	0.1	-0.8	-0.3	-0.4	-0.0	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	5.3	2.0	-0.8	-0.7	-0.6	0.9	-0.1	-0.2	0.5	-0.0	0.6	-1.0	-0.5	-0.9	0.2	0.4	0.5	0.5	-0.7	0.1	-0.1	-1.4	-2.3	-0.6	0.3
Illnesses of siblings	0.3	0.4	2.2	1.3	-0.1	0.1	0.1	0.4	0.8	-0.1	0.3	-0.4	1.5	-0.0	0.2	0.0	0.0	0.3	1.2	1.1	0.6	0.3	0.3	0.3	-1.0	0.1	0.2
Exposure to tobacco smoke at home	0.3	0.3	2.0	-1.1	0.3	-0.1	-0.3	-0.1	0.3	-0.2	0.1	0.3	1.4	0.3	0.8	0.7	-0.1	0.2	0.3	-0.0	-0.4	0.6	-0.3	0.9	1.1	0.5	-0.2
Birth weight of first child	0.3	0.5	2.5	-0.3	-0.1	0.8	1.6	0.4	0.9	0.6	0.5	-0.4	-0.2	0.6	0.6	0.6	0.7	0.6	0.7	0.1	1.2	0.5	0.3	1.2	0.6	0.9	0.3
Peak expiratory flow (PEF)	0.3	0.6	6.9	-2.6	0.4	-0.8	-0.6	-0.6	-0.5	-0.4	-0.3	0.4	-0.5	-0.0	0.8	0.9	-0.2	-0.3	-0.1	-0.5	-0.3	-0.3	-0.8	0.7	1.3	0.1	-0.3
High blood pressure (siblings)	0.3	0.4	3.7	-0.4	0.3	-0.2	-0.3	-0.4	-1.0	-0.0	-0.4	0.3	-0.8	-0.5	-0.2	-0.1	-0.3	-0.4	-1.9	-0.9	-0.6	-0.7	-1.1	-0.8	0.0	-0.5	-0.3
Mean time to correctly identify matches	0.3	0.6	4.5	-0.7	-0.2	-0.9	-1.2	0.2	0.3	-0.4	0.1	-0.1	-1.1	-0.0	0.4	0.2	0.1	0.2	1.4	-1.2	-0.9	0.8	0.3	0.1	2.1	0.8	0.3
Whole body fat mass	0.3	1.1	4.7	-2.0	0.6	-2.2	-1.9	-0.5	-0.9	-0.9	-0.4	0.2	1.5	0.3	0.6	0.6	-0.7	-0.3	2.0	-0.3	0.7	0.5	-0.7	-0.2	1.3	0.2	-0.3
Ever had bowel cancer screening	0.3	0.3	2.4	0.1	0.0	0.3	0.5	-0.2	-0.2	0.3	-0.2	0.4	-1.5	-0.0	-0.6	-0.4	0.2	-0.2	-0.7	-0.5	1.4	-0.3	0.5	-0.3	0.4	-0.5	-0.1
Medication: Gliclazide	0.3	0.3	1.5	1.2	-0.8	0.1	0.3	0.7	0.7	0.7	0.5	-0.5	-0.4	0.4	-0.5	-0.5	0.6	0.4	0.1	0.2	0.9	0.6	1.1	-0.2	-0.1	0.3	0.6
Medication: Lisinopril	0.3	0.4	3.6	0.2	-0.1	-0.4	-0.4	0.0	-0.3	-0.5	-0.2	0.1	-0.9	0.4	-0.8	-0.9	-0.2	-0.2	1.9	-0.4	0.0	0.4	0.2	-1.2	1.1	-0.3	-0.0
Leg fat percentage (left)	0.3	1.2	4.8	0.6	0.5	-2.1	-2.2	-0.3	-0.8	-1.2	-0.6	0.3	1.7	-0.8	-0.9	-1.1	-1.0	-0.6	2.1	-0.5	0.1	0.2	-0.5	-1.8	-0.3	-0.6	-0.5
Number of operations (self-reported)	0.3	0.4	1.3	0.3	-0.4	0.9	1.0	0.7	1.1	0.8	0.6	-0.6	-0.1	-0.2	0.3	0.4	0.5	0.6	-0.7	-1.1	0.9	0.1	-1.1	-0.1	-0.4	0.2	0.5
Cholesterol lowering medication	0.3	0.4	2.3	-0.1	0.0	-0.1	0.0	0.1	-0.6	-0.1	-0.0	-0.1	-1.0	-1.3	-0.5	-0.5	-0.1	-0.1	-1.2	-0.5	0.0	-0.0	-0.9	-0.8	-1.5	-0.6	-0.2
Pain experienced in last month	0.3	0.4	4.7	0.4	0.1	0.8	0.5	-0.1	0.6	-0.3	-0.1	0.6	-0.2	0.6	-0.1	-0.4	0.0	-0.1	0.8	-0.4	-0.9	0.5	2.2	0.5	0.9	0.6	-0.3
Alcohol drinker status: Previous	0.3	0.3	0.9	0.7	-0.8	-0.4	-0.5	0.7	0.5	0.8	0.6	-0.8	-0.6	0.2	-0.2	-0.1	0.4	0.5	-0.4	0.4	0.5	0.5	0.7	-0.4	-0.3	0.1	1.0
Alzheimer’s Disease (in mother)	0.2	0.3	1.3	-0.3	0.0	-0.0	0.1	0.2	0.5	0.3	0.2	-0.7	-0.6	0.6	0.4	0.4	0.1	0.2	1.1	-0.1	0.7	0.5	0.3	0.6	0.9	0.6	0.5
Crohns Disease (2017)	0.2	0.4	1.5	-1.1	-0.3	0.7	0.3	0.3	0.7	0.3	0.4	-0.1	-1.0	0.3	0.4	0.5	0.4	0.4	-1.2	0.4	-0.2	0.5	0.5	0.8	0.7	0.7	0.3
Respiratory disease	0.2	0.4	1.2	-0.2	-0.3	-0.3	-0.2	0.3	-0.2	0.5	0.5	-0.8	0.8	0.4	1.0	1.0	0.3	0.5	-0.2	0.7	0.0	0.9	0.9	1.1	0.7	0.6	0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.3	1.4	-0.6	-1.1	-0.9	0.5	-0.3	-0.4	0.2	0.3	0.7	-0.9	-0.5	-0.7	-0.1	0.1	0.5	0.5	-0.7	-0.1	0.3	-1.3	-1.5	-0.7	0.0
Waist circumference	0.2	0.8	5.6	-0.8	-0.8	-0.0	0.1	1.1	0.3	1.2	1.0	-1.8	0.3	0.4	0.4	0.6	0.7	0.9	-0.1	0.7	0.7	0.5	-2.4	-0.4	-0.8	0.1	1.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.6	0.5	-0.0	0.0	-0.1	0.2	0.5	0.6	0.1	-0.4	0.0	-0.0	-0.6	-0.3	-0.0	-0.0	-1.0	0.3	-0.0	-0.5	-1.3	-0.6	-1.2	-0.7	0.2
Father’s age at death	0.2	0.2	1.3	0.2	0.3	0.6	1.1	-0.4	0.4	0.3	-0.3	-0.1	-0.2	0.3	0.1	0.2	-0.1	-0.2	-1.1	-0.1	-1.0	-0.2	-0.3	0.5	0.6	0.1	-0.1
Number of live births	0.2	0.3	1.7	1.3	-0.1	0.2	0.3	0.1	0.1	0.1	-0.0	0.3	0.6	-0.6	-0.8	-0.9	0.1	-0.0	0.3	0.4	0.3	-0.3	1.3	-0.6	-1.3	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	6.4	-2.5	-0.2	0.4	0.4	0.0	-0.0	0.4	0.2	-0.2	-2.0	0.4	0.8	1.1	0.4	0.2	-1.2	-0.2	0.4	-0.4	-1.0	0.7	1.2	0.1	0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	2.4	-0.3	0.5	-1.1	-1.1	-0.5	-1.5	-0.5	-0.5	0.2	0.2	-0.9	-0.1	-0.1	-0.5	-0.4	-0.2	0.1	-0.6	-0.3	0.4	-0.5	0.1	-0.3	-0.0
Lung cancer (father)	0.2	0.3	1.2	0.1	-0.4	1.1	0.8	0.4	0.9	0.3	0.4	-0.4	-0.1	0.8	0.5	0.4	0.4	0.4	1.1	-0.0	-0.2	0.5	0.1	0.4	0.0	0.3	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	4.2	-2.1	-0.3	0.8	0.6	0.1	-0.1	0.6	0.3	-0.3	-2.0	0.1	0.7	0.9	0.5	0.3	-1.3	-0.2	0.5	-0.3	-1.2	0.5	0.5	0.1	0.5
Body fat percentage	0.2	0.7	6.0	-0.3	-0.5	-0.9	-0.7	0.7	0.5	0.2	0.6	-0.8	0.9	0.9	0.7	0.5	0.3	0.6	2.4	0.4	1.0	1.4	0.3	0.1	0.8	0.8	0.8
Heart disease (mother)	0.2	0.2	2.1	0.2	-0.5	-0.2	-0.8	0.6	0.1	-0.2	0.4	-0.2	-0.2	0.2	-0.1	-0.1	0.2	0.3	0.7	0.4	1.4	0.7	0.8	-0.2	0.2	0.3	0.1
Leg pain on walking	0.2	0.3	1.1	0.8	-0.3	-0.7	-0.8	0.5	-0.3	0.1	0.2	-0.5	-0.3	-0.6	-0.4	-0.5	0.0	0.2	-1.1	0.5	-1.0	0.0	-0.0	-0.9	-0.6	-0.3	0.7
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.2	0.2	0.2	-0.5	-0.8	-0.1	0.0	-0.4	-0.0	0.1	0.1	-0.0	0.6	0.5	-0.2	0.0	0.8	0.6	0.5	0.9	0.6	0.4	1.1	0.6	-0.1
Illnesses of father: Heart disease	0.2	0.3	2.8	0.6	-0.2	0.1	-0.6	0.5	0.7	-0.3	0.2	0.2	-0.9	-0.3	-0.7	-0.8	-0.0	0.1	1.7	-0.1	-0.6	0.2	0.3	-1.0	0.4	-0.3	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.3	0.8	-0.4	-0.1	0.2	0.6	0.2	0.6	0.4	-1.1	-0.4	-0.1	0.0	0.1	0.3	0.4	0.3	0.3	1.1	0.2	-0.2	-0.5	-0.2	0.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	2.7	0.2	-0.0	0.4	0.1	0.1	0.1	-0.4	-0.1	1.0	-0.8	-1.1	-0.9	-1.1	-0.0	-0.2	-0.5	-0.6	-0.8	-0.8	-0.0	-0.9	-1.6	-0.9	-0.7
Financial situation satisfaction	0.2	0.2	0.5	-0.1	-0.5	-0.4	0.2	0.7	-0.2	0.7	0.6	-0.7	-0.2	-0.5	0.5	0.7	0.6	0.7	-0.5	0.4	0.5	0.3	0.2	0.2	0.1	0.4	0.7
Average weekly beer plus cider intake	0.2	0.3	3.4	-0.2	0.0	0.3	0.4	0.2	-0.1	-0.2	0.2	-0.3	-1.2	-0.4	0.1	-0.2	0.1	0.3	0.4	-0.3	-1.9	0.7	0.1	0.6	-0.3	0.5	0.2
Ever depressed for a whole week	0.2	0.3	1.7	0.8	-0.2	0.2	-0.0	0.4	1.3	0.5	0.3	-0.6	0.8	-0.1	-0.1	0.0	0.1	0.2	-0.3	0.1	0.3	0.1	-1.0	-0.4	-1.1	-0.2	0.3
Supplements: Calcium	0.2	0.2	1.1	-0.5	-0.1	-0.3	-0.2	0.2	0.3	0.2	0.2	-0.3	-0.5	0.0	0.5	0.7	0.1	0.3	-1.1	0.1	0.7	-0.1	-1.0	-0.0	0.5	0.2	0.3
Coronary Artery Disease (CAD)	0.1	0.1	1.2	0.4	0.0	0.0	-0.6	0.2	-0.3	-0.2	0.1	-0.3	-0.8	-0.2	-0.3	-0.4	-0.2	0.2	0.2	0.1	-0.2	-0.1	1.1	-0.5	-0.0	0.0	0.3
Lupus	0.1	0.1	0.8	0.4	-0.1	-0.4	-0.2	0.1	0.2	-0.1	0.1	-0.0	-0.3	0.3	0.3	0.3	-0.0	0.1	0.2	0.9	0.0	-0.1	0.1	0.2	0.1	0.3	0.0
Diabetes (father)	0.1	0.1	1.3	0.3	-0.1	-0.3	0.1	0.0	0.1	0.4	-0.1	-0.3	0.1	-0.1	-0.3	-0.2	0.1	-0.1	0.4	-0.5	0.0	-0.1	-1.1	-0.4	-0.1	-0.0	0.1
Chronic bronchitis/emphysema (father)	0.1	0.2	1.0	-0.5	-0.1	0.2	0.6	0.1	-0.2	0.1	0.1	0.1	-0.6	-0.1	-0.0	-0.2	0.4	0.2	-0.3	-0.2	-1.0	0.1	0.6	0.5	0.8	0.2	0.1
Asthma	0.1	0.1	1.0	0.3	-0.0	-0.4	-0.5	0.2	-0.1	0.3	0.2	-0.5	1.0	-0.1	0.4	0.3	-0.0	0.3	-0.3	0.0	0.1	0.2	-0.2	0.1	-1.0	-0.0	0.4
Health satisfaction	0.1	0.1	1.2	-0.5	-0.3	-0.1	-0.0	0.3	-0.4	0.5	0.2	-0.3	-0.2	-0.4	-0.0	0.2	0.2	0.1	-1.1	0.4	0.2	-0.0	-0.5	-0.5	-0.3	-0.3	0.2
Supplements: Vitamin C	0.1	0.1	1.3	0.2	-0.4	0.4	0.2	0.3	0.3	0.4	0.2	-0.3	-1.1	0.1	-0.1	-0.0	0.1	0.1	-0.6	0.1	0.3	0.2	0.2	-0.3	0.5	-0.1	0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.5	-0.6	0.2	-0.4	-0.6	-0.2	0.2	0.1	-0.1	0.1	0.3	0.1	0.5	0.7	-0.2	-0.0	-0.6	0.4	0.4	-0.0	-0.3	0.1	0.4	-0.0	-0.1
Asthma (self-reported)	0.1	0.2	0.8	0.2	-0.2	-0.1	-0.2	0.3	0.1	0.5	0.4	-0.6	0.9	0.1	0.5	0.4	0.1	0.4	-0.4	0.2	0.2	0.3	-0.1	0.3	-0.9	0.1	0.5
Osteoporosis (self-reported)	0.1	0.1	0.8	0.0	0.2	0.6	0.4	-0.1	0.3	-0.2	-0.2	0.2	0.4	-0.1	-0.2	-0.3	-0.2	-0.1	-0.1	-0.3	-0.9	-0.8	-0.6	-0.3	-0.2	-0.4	0.0
Hair Pigment	0.0	0.2	1.1	0.8	0.6	-0.4	0.0	-0.5	-1.1	-0.5	-0.5	0.1	-0.3	-1.0	-0.2	-0.3	-0.5	-0.4	0.6	-0.4	0.5	0.2	-0.3	-0.3	-0.1	0.0	-0.4
Number of self-reported non-cancer illnesses	0.0	0.1	0.3	-0.3	-0.0	0.6	0.2	0.2	-0.0	0.2	0.2	0.1	-0.2	0.3	0.1	0.1	0.2	0.2	0.6	0.1	0.4	0.1	-0.2	-0.4	-0.2	-0.2	-0.1

Hub : Genes

NT5DC2

Models

Trait associations