[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr3:153,142,317-154,733,231

Best TWAS P=1.72e-11 · Best GWAS P=1.09e-10 conditioned to 0.302

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -5.7 -5.8 8.8e-09 -0.55 0.41 0.59 FALSE
2 GTEx Adipose Subcutaneous ARHGEF26 0.10 0.06 enet 8 0.07 2.2e-06 -5.7 5.8 8.9e-09 0.47 0.32 0.67 FALSE
3 GTEx Artery Tibial ARHGEF26 0.11 0.12 enet 12 0.12 5.9e-10 -5.7 5.2 1.8e-07 0.44 0.42 0.58 FALSE
4 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 6.5 6.7 1.7e-11 0.89 0.03 0.78 TRUE
5 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -5.6 6.5 5.8e-11 0.52 0.34 0.66 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic ARHGEF26 0.13 0.11 lasso 4 0.07 6.8e-05 -5.6 6.2 5.5e-10 0.50 0.36 0.62 FALSE
7 GTEx Skin Sun Exposed Lower leg ARHGEF26 0.10 0.08 enet 12 0.11 2.9e-09 -5.7 5.6 1.6e-08 0.40 0.42 0.58 FALSE
8 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -5.8 5.8 6.3e-09 0.46 0.36 0.61 FALSE
9 METSIM Adipose ARHGEF26 0.07 0.08 lasso 6 0.07 3.5e-11 -5.7 5.8 5.0e-09 0.50 0.41 0.59 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -5.5 6.3 4.0e-10 0.55 0.15 0.80 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -4.9 -5.1 3.0e-07 -0.57 0.96 0.04 FALSE