Best TWAS P=1.28e-09 · Best GWAS P=3.66e-09 conditioned to 0.0123
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | REEP5 | 0.09 | 0.05 | lasso | 5 | 0.02 | 4.9e-02 | 5.1 | 5.2 | 2.5e-07 | -0.60 | 0.04 | 0.90 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | REEP5 | 0.18 | 0.03 | lasso | 3 | 0.03 | 3.7e-02 | 5.3 | 5.2 | 1.5e-07 | -0.61 | 0.03 | 0.88 | FALSE |
| 3 | GTEx | Esophagus Mucosa | REEP5 | 0.19 | 0.10 | lasso | 5 | 0.09 | 1.5e-06 | 5.3 | 5.2 | 1.7e-07 | -0.60 | 0.05 | 0.93 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | REEP5 | 0.11 | 0.10 | lasso | 7 | 0.10 | 6.3e-06 | 4.8 | 5.2 | 1.6e-07 | -0.63 | 0.13 | 0.85 | FALSE |
| 5 | GTEx | Testis | REEP5 | 0.22 | 0.14 | lasso | 5 | 0.14 | 6.6e-07 | 5.0 | 5.4 | 7.6e-08 | -0.59 | 0.08 | 0.91 | FALSE |
| 6 | NTR | Blood | REEP5 | 0.03 | 0.04 | lasso | 9 | 0.04 | 3.3e-12 | 5.9 | 6.1 | 1.3e-09 | -0.66 | 0.01 | 0.99 | TRUE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | APC | 0.03 | 0.02 | blup | 77 | 0.02 | 5.2e-03 | 4.9 | 5.2 | 2.5e-07 | -0.45 | 0.02 | 0.47 | FALSE |