[Hub]/) : Traits : Leg predicted mass (right) :

chr5:121,983,336-123,649,166

Best TWAS P=3.11e-28 · Best GWAS P=6.27e-39 conditioned to 2.11e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CEP120 0.12 0.08 lasso 3 0.05 5.5e-05 4.8 5.3 9.6e-08 -0.29 0.87 0.01 FALSE
2 GTEx Artery Aorta CSNK1G3 0.11 0.07 lasso 2 0.01 6.5e-02 -6.5 -6.7 1.9e-11 0.52 0.15 0.09 FALSE
3 GTEx Artery Aorta KRT8P33 0.10 0.04 lasso 6 0.05 9.1e-04 -6.4 8.8 1.2e-18 -0.62 0.03 0.87 FALSE
4 GTEx Cells EBV-transformed lymphocytes KRT8P33 0.16 -0.01 lasso 8 0.01 2.1e-01 6.5 5.2 1.8e-07 -0.36 0.08 0.33 FALSE
5 GTEx Esophagus Mucosa CSNK1G3 0.14 0.05 lasso 3 0.07 2.0e-05 7.4 7.3 3.4e-13 -0.44 0.78 0.11 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma CSNK1G3 0.04 0.02 enet 8 0.02 1.2e-04 7.5 8.6 9.4e-18 -0.56 0.00 0.91 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma CEP120 0.06 0.02 blup 70 0.04 3.6e-03 5.4 8.3 7.3e-17 -0.64 0.13 0.15 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CEP120 0.03 0.02 enet 5 0.04 7.3e-05 -6.4 8.4 4.1e-17 -0.66 0.03 0.83 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma CSNK1G3 0.06 0.05 lasso 2 0.04 2.0e-05 7.4 7.3 3.2e-13 -0.44 0.00 1.00 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma CEP120 0.10 0.14 blup 70 0.14 2.6e-14 -11.9 11.0 3.1e-28 -0.83 0.17 0.83 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma CSNK1G3 0.06 0.04 enet 10 0.05 2.3e-06 7.0 8.5 2.2e-17 -0.57 0.05 0.94 FALSE