TWAS hub - REEP5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0880	0.0250	1.4e-06	0.033	0.042	0.066	0.051	0.076	6.0e-05	6.3e-06	1.7e-08	6.5e-07	1.7e-09
2	GTEx	Adipose Subcutaneous	0.0950	0.0350	1.9e-04	0.089	NA	0.012	NA	0.055	9.7e-08	NA	3.6e-02	NA	2.8e-05
3	GTEx	Adipose Visceral Omentum	0.0890	0.0420	7.6e-03	0.049	NA	-0.004	NA	0.016	1.4e-03	NA	6.2e-01	NA	4.9e-02
4	GTEx	Artery Aorta	0.1670	0.0580	1.8e-05	0.065	NA	0.093	NA	0.099	1.8e-04	NA	8.2e-06	NA	4.2e-06
5	GTEx	Artery Tibial	0.1663	0.0440	9.0e-08	0.118	NA	0.124	NA	0.128	1.7e-09	NA	6.3e-10	NA	3.0e-10
6	GTEx	Breast Mammary Tissue	0.1160	0.0530	5.9e-03	-0.006	NA	-0.005	NA	-0.005	9.7e-01	NA	9.0e-01	NA	7.5e-01
7	GTEx	Colon Transverse	0.1170	0.0460	1.5e-03	0.143	NA	0.090	NA	0.138	2.6e-07	NA	4.7e-05	NA	4.4e-07
8	GTEx	Esophagus Gastroesophageal Junction	0.1810	0.0780	3.5e-03	0.034	NA	0.012	NA	0.027	2.1e-02	NA	1.1e-01	NA	3.7e-02
9	GTEx	Esophagus Mucosa	0.1880	0.0580	4.3e-05	0.101	NA	0.042	NA	0.089	2.8e-07	NA	8.5e-04	NA	1.6e-06
10	GTEx	Esophagus Muscularis	0.1830	0.0460	2.3e-08	0.086	NA	0.108	NA	0.142	7.1e-06	NA	4.2e-07	NA	5.9e-09
11	GTEx	Muscle Skeletal	0.0789	0.0330	1.2e-03	0.003	NA	0.001	NA	0.000	1.5e-01	NA	2.7e-01	NA	2.8e-01
12	GTEx	Nerve Tibial	0.1575	0.0523	2.4e-05	0.134	NA	0.084	NA	0.103	1.1e-09	NA	1.6e-06	NA	9.2e-08
13	GTEx	Pituitary	0.1880	0.0820	5.5e-03	0.020	NA	0.018	NA	0.018	1.0e-01	NA	1.1e-01	NA	1.1e-01
14	GTEx	Skin Not Sun Exposed Suprapubic	0.1150	0.0430	2.3e-04	0.103	NA	0.065	NA	0.096	2.7e-06	NA	1.8e-04	NA	6.3e-06
15	GTEx	Skin Sun Exposed Lower leg	0.0830	0.0310	3.4e-04	0.047	NA	0.023	NA	0.029	9.0e-05	NA	4.8e-03	NA	1.9e-03
16	GTEx	Testis	0.2150	0.0650	9.3e-05	0.141	NA	0.134	NA	0.143	8.4e-07	NA	1.6e-06	NA	6.6e-07
17	GTEx	Thyroid	0.0900	0.0330	1.1e-03	0.021	NA	0.021	NA	0.027	9.2e-03	NA	9.6e-03	NA	3.3e-03
18	GTEx	Uterus	0.3850	0.1170	5.3e-04	0.051	NA	0.073	NA	0.098	3.5e-02	NA	1.4e-02	NA	5.1e-03
19	METSIM	Adipose	0.0533	0.0238	4.4e-04	0.004	0.011	0.008	0.011	0.010	8.2e-02	7.5e-03	2.2e-02	6.8e-03	1.0e-02
20	NTR	Blood	0.0301	0.0088	7.9e-10	0.041	0.033	0.035	0.035	0.038	3.3e-13	5.8e-11	1.4e-11	1.3e-11	3.3e-12
21	ROSMAP	Brain Pre-frontal Cortex	0.0826	0.0350	2.9e-03	0.034	0.007	0.009	0.010	0.020	2.9e-05	3.7e-02	1.9e-02	1.8e-02	1.2e-03
22	YFS	Blood	0.0929	0.0217	5.0e-16	0.044	0.063	0.060	0.060	0.060	3.2e-14	7.5e-20	6.4e-19	5.6e-19	6.4e-19
23	TCGA	Stomach Adenocarcinoma	0.0270	0.0200	9.3e-03	0.020	0.028	0.017	NA	0.013	1.3e-02	4.1e-03	1.9e-02	NA	3.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	12	13	14	15	16	17	18	19	20	21	22	23
Reaction Time	13.4	25.5	43.6	3.6	4.9	5.5	6.6	4.9	3.8	5.6	5.5	5.2	5.7	5.1	5.2	4.8	5.1	5.9	4.8	4.7	5.0	6.4	3.9	4.7	5.7
Mean time to correctly identify matches	13.2	25.2	41.5	3.2	5.0	5.6	6.4	5.1	3.7	5.7	5.5	5.3	5.7	5.3	4.8	4.9	5.2	6.0	4.9	3.9	4.8	6.3	4.0	4.0	5.8
Pulse wave Arterial Stiffness index	6.2	7.2	13.0	-0.1	2.9	3.3	3.1	3.3	-0.5	3.3	2.8	3.3	3.1	3.6	2.9	3.2	3.0	3.5	2.5	1.7	2.0	2.9	0.2	-0.3	3.4
Osteoporosis (self-reported)	5.7	7.1	15.4	-2.4	-2.9	-2.5	-3.1	-2.5	-2.8	-2.3	-2.4	-2.5	-2.8	-2.4	-3.4	-2.8	-3.0	-2.4	-1.9	-3.9	-3.1	-2.9	-2.0	-2.3	-2.7
Arm fat-free mass (left)	5.0	25.2	46.9	2.6	5.3	5.7	6.1	5.3	2.5	5.7	5.8	6.0	5.4	5.2	4.3	5.7	5.3	6.0	3.5	3.6	4.9	6.8	4.5	4.4	5.6
Pulse wave peak to peak time	4.9	5.8	10.9	0.4	-2.6	-3.0	-2.7	-3.0	0.4	-2.9	-2.4	-2.9	-2.8	-3.3	-2.7	-2.9	-2.7	-3.1	-2.2	-1.5	-1.8	-2.5	0.1	0.6	-3.0
Arm fat-free mass (right)	4.8	24.6	47.6	2.5	5.2	5.7	6.1	5.2	1.9	5.7	6.0	6.2	5.4	5.2	3.9	5.6	5.2	6.2	3.3	3.3	4.7	6.9	4.3	4.2	5.6
Chest pain or discomfort	4.8	6.9	14.1	1.8	3.3	3.0	3.8	3.0	1.6	2.8	3.3	2.9	3.3	2.7	1.9	3.2	3.4	2.9	2.4	1.7	1.6	3.0	0.8	-0.9	3.1
Basal metabolic rate	4.8	26.5	48.9	2.0	5.6	5.9	6.0	5.5	2.3	5.8	5.9	6.1	5.4	5.4	4.4	6.0	5.4	6.2	3.6	3.7	5.2	7.0	4.6	4.8	5.7
Arm predicted mass (right)	4.7	24.1	47.3	2.6	4.9	5.5	6.0	5.0	1.8	5.6	5.9	6.1	5.3	5.1	4.0	5.4	5.0	6.1	3.3	3.4	4.8	6.9	4.6	4.5	5.5
Arm predicted mass (left)	4.7	24.0	46.2	2.7	5.2	5.5	6.0	5.1	2.3	5.5	5.7	5.9	5.3	5.0	4.0	5.5	5.2	6.0	3.4	3.3	4.8	6.8	4.5	4.4	5.5
Whole body fat-free mass	4.6	26.0	46.9	2.2	5.5	5.9	6.0	5.5	2.1	5.9	6.0	6.1	5.5	5.4	4.2	5.9	5.3	6.2	3.7	3.5	5.1	6.8	4.6	4.6	5.7
Whole body water mass	4.6	26.2	47.9	2.4	5.5	5.9	6.0	5.5	2.1	5.9	6.1	6.1	5.5	5.3	4.1	5.8	5.3	6.2	3.7	3.5	5.0	6.9	4.7	4.6	5.7
Trunk fat-free mass	4.5	25.7	46.4	2.8	5.3	5.8	6.0	5.3	1.8	5.8	6.0	6.1	5.5	5.3	4.2	5.6	5.3	6.2	3.9	3.6	4.8	6.8	4.7	4.5	5.7
Trunk predicted mass	4.5	25.4	46.0	2.7	5.3	5.8	6.0	5.3	1.9	5.8	6.0	6.1	5.5	5.3	4.1	5.6	5.3	6.2	3.9	3.5	4.7	6.8	4.7	4.4	5.7
Medication: Ibuprofen (e.g. Nurofen)	4.2	5.4	8.7	0.5	2.9	2.9	3.0	2.4	0.6	2.7	2.9	2.6	2.7	2.5	2.0	2.9	2.7	2.7	1.4	1.9	1.6	2.8	1.1	2.4	2.5
Heel T-Score	4.1	32.7	56.1	4.5	5.9	6.3	7.5	6.2	1.9	6.6	7.0	6.6	6.6	6.4	3.9	6.0	6.1	6.8	5.3	3.9	6.2	7.0	5.2	2.0	6.6
Leg predicted mass (left)	4.1	21.5	37.6	1.2	5.2	5.4	5.2	5.1	2.0	5.3	5.3	5.5	4.8	4.9	4.0	5.6	4.9	5.5	3.0	3.3	5.0	6.1	4.0	4.4	5.1
BMI	4.0	23.4	38.1	-0.2	5.7	5.5	5.3	5.5	3.7	5.2	4.7	5.3	4.9	5.5	5.7	6.1	5.3	5.4	2.0	4.3	6.2	6.0	2.7	3.7	5.1
Leg fat-free mass (left)	4.0	21.4	37.6	1.3	5.2	5.4	5.2	5.1	2.0	5.2	5.4	5.5	4.8	4.9	3.9	5.6	4.9	5.5	3.0	3.2	5.0	6.1	4.1	4.3	5.0
Weight	4.0	19.4	37.0	1.2	5.0	4.9	5.3	4.6	2.6	4.7	4.8	5.0	4.5	4.4	4.3	5.3	4.7	5.1	2.8	3.7	4.8	6.1	3.5	4.5	4.7
Guilty feelings	4.0	6.1	10.9	-1.7	-2.4	-2.8	-3.1	-2.4	-3.3	-2.9	-2.5	-2.7	-2.8	-3.2	-2.0	-2.6	-2.4	-3.0	-0.0	-2.3	-2.0	-2.9	-2.0	-2.2	-2.7
Ever had hysterectomy (womb removed)	3.9	4.4	12.6	1.1	2.0	1.7	2.9	1.8	2.0	1.6	2.1	2.2	1.8	2.0	2.3	2.0	2.0	2.2	1.6	3.6	1.9	3.1	1.4	2.4	2.1
Arm fat mass (right)	3.7	15.1	26.0	0.2	4.6	4.3	4.4	4.2	2.4	4.0	3.7	4.0	3.9	4.0	4.5	4.9	4.3	4.3	2.2	3.7	4.7	5.1	2.8	3.9	4.1
Knee pain experienced in last month	3.7	5.8	11.3	2.5	2.7	2.4	3.4	2.2	2.2	2.0	2.2	2.3	2.7	2.6	2.3	2.7	3.0	2.3	1.8	2.9	2.1	2.6	2.0	1.1	3.0
Medication for pain relief, constipation, heartburn	3.6	6.1	10.3	-0.2	-3.1	-3.2	-3.0	-3.0	-1.5	-2.9	-2.7	-2.6	-3.0	-2.9	-1.9	-3.1	-3.1	-2.7	-2.1	-1.3	-2.4	-2.6	-1.1	-1.1	-2.9
Leg fat-free mass (right)	3.6	19.1	36.6	1.1	4.8	5.2	5.0	4.8	1.7	5.1	5.3	5.2	4.5	4.5	3.5	5.2	4.4	5.4	2.7	2.6	4.6	6.0	4.0	4.3	4.7
Leg predicted mass (right)	3.6	19.2	36.8	1.1	4.9	5.2	5.0	4.8	1.8	5.1	5.2	5.2	4.5	4.6	3.5	5.2	4.5	5.4	2.7	2.6	4.6	6.1	4.0	4.2	4.7
Worry (Nagel 2018)	3.5	7.3	11.7	-2.1	-2.9	-3.0	-3.4	-2.6	-1.9	-3.0	-3.2	-3.0	-3.0	-2.8	-2.1	-2.8	-3.0	-3.2	-2.8	-1.6	-1.7	-3.3	-2.8	-1.9	-3.3
Medication: Ibuprofen	3.5	4.2	7.1	0.8	2.7	2.6	2.6	2.1	0.4	2.5	2.4	2.3	2.5	2.3	1.8	2.7	2.5	2.4	0.8	1.7	1.3	2.2	0.8	1.6	2.4
Hearing aid user	3.5	4.0	14.1	-0.6	2.5	2.4	2.0	2.5	3.8	2.2	1.9	2.4	2.1	2.5	1.4	2.4	2.3	2.0	1.7	0.9	1.2	1.7	-0.8	-0.2	2.2
Other serious medical condition/disability diagnosed by doctor	3.4	4.4	8.9	1.1	2.7	2.4	2.3	2.5	2.7	2.0	1.2	1.5	2.5	3.0	2.3	2.6	2.8	1.9	1.9	1.7	1.4	1.6	1.9	0.8	2.6
Eye problems/disorders: Diabetes related eye disease	3.4	3.7	7.0	1.0	-1.8	-2.4	-1.8	-2.3	1.3	-2.6	-2.1	-2.2	-2.0	-2.6	-1.6	-1.9	-1.6	-2.6	-1.6	-0.9	-1.8	-2.2	-1.3	-2.1	-1.9
Hair/balding pattern: Pattern 2	3.3	4.3	8.5	2.3	2.2	1.9	2.9	2.1	2.2	1.7	2.0	1.9	2.1	2.2	2.2	2.2	2.3	1.8	1.5	2.7	1.5	2.2	2.3	1.0	2.3
Leg fat mass (right)	3.2	12.5	21.3	0.2	4.0	3.9	4.0	3.8	2.4	3.6	3.4	3.8	3.5	3.6	4.3	4.3	3.9	3.9	2.1	3.6	4.1	4.6	2.2	3.6	3.7
Arm fat mass (left)	3.2	13.0	23.2	0.1	4.3	4.0	4.1	3.9	2.4	3.6	3.4	3.7	3.5	3.8	4.2	4.6	4.0	3.9	1.8	3.6	4.2	4.8	2.7	3.9	3.7
Waist circumference	3.1	11.3	19.9	-0.1	4.2	3.9	4.0	3.9	2.2	3.6	3.5	3.8	3.5	3.8	3.5	4.5	3.9	3.8	1.8	2.5	3.7	4.3	1.7	2.6	3.7
Illnesses of mother	3.1	3.8	7.5	-1.0	-2.3	-2.2	-2.7	-2.1	-1.7	-2.0	-2.3	-2.0	-2.3	-1.6	-1.6	-2.2	-2.4	-2.1	-2.5	-1.1	-1.9	-2.4	-1.0	-0.3	-2.3
Worrier / anxious feelings	3.0	5.6	9.7	-2.5	-2.5	-2.6	-3.1	-2.3	-1.1	-2.7	-2.9	-2.9	-2.7	-2.5	-1.1	-2.5	-2.6	-3.0	-2.2	-1.0	-1.6	-3.0	-2.6	-1.1	-2.8
Whole body fat mass	3.0	12.4	23.1	0.6	4.0	3.8	4.1	3.7	2.1	3.6	3.3	3.6	3.5	3.5	4.2	4.3	3.8	3.9	2.0	3.6	4.1	4.8	2.5	4.0	3.7
Age started oral contraceptive pill	3.0	3.7	6.8	-0.4	-2.3	-2.2	-1.9	-2.2	-0.7	-2.1	-2.4	-2.5	-1.8	-1.8	-1.2	-2.3	-2.0	-2.2	-1.3	-1.4	-2.3	-2.6	-2.0	-2.1	-2.0
Leg fat mass (left)	3.0	11.9	21.4	0.4	4.0	3.8	4.0	3.7	2.3	3.6	3.5	3.7	3.4	3.5	4.0	4.2	3.8	3.9	2.0	3.3	4.0	4.6	2.2	3.5	3.6
Medication: Bendroflumethiazide	2.9	4.4	6.7	1.3	2.1	2.2	2.6	2.4	1.8	2.4	2.3	2.5	2.5	2.1	1.8	2.3	2.3	2.6	2.0	1.2	2.6	2.4	0.8	1.1	2.4
Medication: Co-codamol	2.8	3.2	11.5	1.7	1.6	1.3	2.0	1.4	0.7	1.3	1.5	1.5	1.6	1.7	3.0	1.5	1.8	1.5	1.1	3.4	1.8	2.3	1.5	2.3	1.6
Sitting height	2.8	19.8	41.9	3.9	4.1	4.5	5.7	3.9	1.3	4.8	5.2	5.2	4.8	4.1	3.5	4.4	4.3	5.5	3.1	3.9	4.1	6.5	5.0	5.0	4.8
Peak expiratory flow (PEF)	2.7	6.2	10.7	-2.9	-2.6	-2.4	-3.3	-2.5	-3.2	-2.3	-2.1	-2.3	-3.0	-2.9	-2.0	-2.4	-3.0	-2.3	-2.1	-2.6	-2.4	-2.3	-2.2	-1.4	-3.0
Number of treatments/medications taken	2.6	4.7	8.0	2.2	2.4	2.4	2.8	2.2	1.8	2.2	2.1	2.0	2.7	2.4	2.1	2.4	2.7	2.0	1.3	2.1	2.5	2.2	1.7	1.3	2.5
Supplements: Glucosamine	2.6	3.4	6.4	0.9	2.0	2.4	1.8	2.4	0.2	2.5	2.5	2.2	2.3	2.3	0.1	1.9	2.0	2.3	2.5	-0.5	0.9	1.7	1.5	0.4	2.3
Trunk fat mass	2.6	11.2	20.8	0.7	3.9	3.5	4.0	3.5	2.2	3.3	3.0	3.3	3.3	3.3	4.0	4.1	3.7	3.6	1.9	3.6	4.0	4.6	2.4	3.8	3.4
Nervous feelings	2.6	4.9	9.0	-2.1	-2.6	-2.4	-2.6	-2.3	-2.6	-2.3	-1.7	-2.0	-2.8	-2.5	-2.0	-2.5	-3.0	-2.5	-2.7	-0.8	-0.8	-1.9	-1.7	-0.7	-3.0
Breastfed as a baby	2.6	3.2	6.2	1.3	1.9	2.2	2.1	2.1	0.4	2.3	1.7	1.8	2.3	2.2	0.2	1.9	2.0	2.3	2.5	0.1	1.2	2.0	1.8	0.1	2.4
Miserableness	2.6	4.6	15.5	2.3	1.9	1.7	2.7	1.4	2.2	1.6	2.0	1.7	2.1	1.4	2.7	1.8	2.1	1.7	1.8	3.9	2.7	2.4	2.0	2.3	2.0
Pain experienced in last month	2.6	4.3	7.2	0.4	-2.5	-2.7	-2.5	-2.4	-1.2	-2.4	-2.0	-1.9	-2.4	-2.3	-2.2	-2.4	-2.5	-2.5	-2.4	-1.5	-1.8	-2.3	0.4	-0.6	-2.6
Depressed Affect (Nagel 2018)	2.5	5.2	10.8	2.7	2.5	2.1	2.9	1.8	1.6	1.9	2.1	2.0	2.6	1.8	2.6	2.3	2.7	1.9	2.2	3.3	2.3	2.4	2.5	1.9	2.5
Smoking Status	2.5	5.9	10.7	1.5	2.6	2.5	3.2	2.5	0.3	2.3	2.9	2.6	2.6	2.4	2.3	2.4	2.9	2.4	3.3	2.4	2.2	3.0	2.4	0.6	3.0
Cardiovascular Disease	2.5	8.2	13.7	2.1	3.1	3.1	3.6	2.8	3.0	2.9	2.8	2.9	3.2	3.0	3.7	3.4	3.3	2.8	1.0	3.6	3.5	2.8	1.2	1.8	3.1
Impedance of arm (right)	2.5	11.5	22.7	-1.5	-3.2	-4.0	-4.0	-3.6	-0.7	-4.2	-4.6	-4.8	-3.7	-3.5	-2.3	-3.6	-3.4	-4.4	-2.4	-1.2	-3.0	-4.5	-3.3	-2.6	-4.0
Impedance of arm (left)	2.5	11.8	21.8	-1.4	-3.3	-4.2	-4.0	-3.7	-1.4	-4.3	-4.6	-4.7	-3.9	-3.5	-2.4	-3.6	-3.5	-4.4	-2.9	-1.3	-3.2	-4.4	-2.9	-2.4	-4.1
Ever had bowel cancer screening	2.4	2.8	5.6	1.5	2.0	2.0	2.4	1.7	2.2	1.9	1.8	1.5	2.2	1.6	1.4	1.7	2.1	1.7	1.6	1.4	1.0	1.7	0.6	0.1	2.0
Height	2.3	43.9	94.1	6.2	6.0	6.5	8.8	6.1	2.1	7.0	7.5	7.6	6.7	6.9	5.1	6.3	6.1	8.1	4.5	6.7	5.9	9.7	7.9	6.8	7.0
Sensitivity / hurt feelings	2.3	3.9	6.8	-0.7	-2.1	-2.2	-2.3	-1.8	-1.4	-2.1	-2.4	-2.3	-2.1	-2.1	-2.0	-2.3	-2.2	-2.3	-0.8	-2.2	-1.1	-2.6	-1.7	-2.1	-2.1
Illnesses of siblings	2.3	3.2	8.1	-2.6	-2.0	-1.7	-2.5	-1.3	-1.6	-1.4	-1.2	-1.2	-2.2	-1.4	-2.2	-2.0	-2.3	-1.6	-1.8	-2.8	-1.3	-1.9	-0.8	0.2	-2.2
Alcohol intake versus 10 years previously	2.3	3.5	5.6	1.6	2.2	1.9	2.1	2.0	2.4	1.6	1.6	1.8	1.9	2.2	2.1	2.3	2.3	1.5	1.0	2.2	1.9	1.7	2.1	1.3	2.0
Leg pain on walking	2.3	2.9	12.5	2.5	1.4	0.9	2.2	1.0	2.1	0.9	1.0	1.4	1.8	1.2	2.8	1.4	2.0	0.9	1.1	3.5	1.7	1.4	1.3	0.8	1.6
Hypertension (Self-reported)	2.3	6.5	9.9	1.5	2.8	2.8	3.1	2.4	2.9	2.7	2.5	2.7	2.9	2.5	3.0	3.0	2.9	2.8	1.1	2.6	2.8	2.9	0.9	2.4	2.8
Diabetes (father)	2.2	2.8	5.6	1.0	1.4	1.8	2.1	1.8	0.7	1.8	1.8	1.8	1.8	2.4	2.1	1.6	1.6	2.1	1.4	2.0	1.1	2.2	1.1	0.7	1.9
Body mass index (BMI)	2.2	9.5	16.7	-0.6	3.7	3.5	3.4	3.5	2.1	3.2	3.1	3.4	2.9	3.2	3.5	4.0	3.4	3.4	1.6	2.5	3.6	4.1	2.0	3.2	3.2
Hip circumference	2.2	9.4	18.5	-0.1	3.6	3.6	3.5	3.4	1.5	3.4	3.4	3.5	3.0	3.0	3.1	3.9	3.3	3.5	1.7	2.0	3.4	4.3	2.2	3.2	3.2
Mouth/teeth dental problems: Mouth ulcers	2.2	3.5	8.1	1.8	-2.3	-2.3	-1.0	-2.8	1.0	-2.4	-2.5	-2.4	-1.6	-2.1	-1.8	-2.3	-1.8	-2.2	-2.0	-0.3	-1.8	-2.0	-0.8	-0.7	-1.9
Impedance of whole body	2.2	11.3	19.6	-0.6	-3.5	-4.2	-3.6	-3.8	-0.9	-4.3	-4.4	-4.4	-3.6	-3.6	-2.4	-3.8	-3.4	-4.2	-2.7	-1.0	-3.2	-4.2	-3.1	-2.6	-3.9
High blood pressure	2.1	5.8	8.6	1.2	2.8	2.6	2.9	2.3	2.5	2.5	2.4	2.5	2.6	2.4	2.9	2.9	2.8	2.5	1.1	2.6	2.5	2.8	0.7	2.3	2.6
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.4	11.8	1.5	2.0	1.9	2.7	1.4	1.2	1.6	1.6	1.3	2.3	1.4	2.5	1.7	2.3	1.7	2.1	3.4	1.2	2.0	0.9	0.6	2.0
Vascular/heart problems diagnosed by doctor	2.1	5.8	9.4	-1.7	-2.7	-2.7	-3.1	-2.3	-2.5	-2.6	-2.6	-2.4	-2.8	-2.3	-2.6	-2.8	-2.8	-2.5	-1.2	-2.5	-2.4	-2.8	-1.1	-2.1	-2.6
Ovarian Cancer	2.0	2.6	5.7	-0.7	1.5	2.0	1.7	2.0	-0.2	2.1	2.0	2.4	1.6	2.1	0.6	1.7	1.4	2.1	1.2	0.6	1.7	2.2	1.0	1.5	1.8
Exposure to tobacco smoke at home	2.0	2.3	5.5	-0.1	2.1	1.8	1.9	2.2	1.4	1.6	1.6	1.4	1.6	1.7	0.6	1.9	1.9	1.5	2.3	-0.1	0.9	1.5	-0.3	-0.6	1.8
Leg fat percentage (right)	2.0	7.4	14.1	-0.4	3.2	2.9	3.1	2.9	1.9	2.7	2.3	2.8	2.7	2.8	3.8	3.4	3.1	2.8	1.6	3.1	3.2	3.4	1.2	2.6	2.8
Neck or shoulder pain in last month	2.0	2.9	7.2	-0.3	1.8	2.2	2.3	1.8	-0.5	2.3	2.3	2.1	1.9	1.8	0.7	1.8	1.6	2.5	1.5	0.3	0.5	2.7	0.8	0.4	2.0
Suffer from ‘nerves’	2.0	3.1	5.7	-1.1	-1.8	-1.9	-2.1	-1.6	-2.4	-2.0	-2.4	-2.0	-2.0	-1.6	-1.4	-1.7	-1.9	-1.9	-1.9	-1.5	-0.8	-1.9	-1.2	-1.8	-2.0
Mood swings	2.0	3.6	8.4	2.3	2.2	1.8	2.9	1.4	1.4	1.6	1.8	1.3	2.2	1.3	1.7	1.8	2.3	1.7	2.1	2.1	2.0	2.3	2.0	1.3	2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.1	8.1	-1.2	-2.7	-2.4	-2.8	-2.1	-2.0	-2.2	-1.9	-2.0	-2.5	-2.1	-2.2	-2.6	-2.7	-2.3	-1.9	-1.1	-1.0	-2.0	-0.7	-0.3	-2.5
Ever used hormone-replacement therapy (HRT)	1.9	2.4	8.4	1.8	1.5	1.7	2.1	1.4	2.9	1.5	1.4	1.6	2.0	1.8	1.2	1.4	2.0	1.3	1.3	0.3	1.0	1.0	1.1	0.4	1.9
Bilateral oophorectomy (both ovaries removed)	1.9	2.1	5.3	0.4	1.7	1.1	2.0	1.1	2.1	0.8	1.1	1.4	1.2	1.3	2.0	1.8	1.8	1.0	0.2	2.1	1.4	1.8	0.1	2.3	1.3
Multivitamins +/- minerals	1.9	2.4	5.5	-1.2	1.8	2.0	1.4	2.0	1.1	2.0	1.9	2.3	1.4	2.3	1.6	1.9	1.5	1.8	0.1	0.6	1.3	1.6	0.3	-0.2	1.5
Comparative height size at age 10	1.9	10.6	17.7	3.0	3.0	3.3	4.2	3.1	1.9	3.7	3.6	3.6	3.7	3.0	3.7	3.1	3.2	4.0	3.3	3.7	3.1	4.2	1.8	1.9	3.7
Financial situation satisfaction	1.9	2.4	5.0	2.2	1.7	1.6	1.6	1.2	2.2	1.4	1.0	1.0	2.0	1.1	1.4	1.5	1.9	1.1	2.2	1.8	1.0	0.5	1.6	-1.3	2.0
Illnesses of father: High blood pressure	1.9	2.3	4.3	-0.0	1.6	1.7	1.6	1.6	1.5	1.9	1.7	2.1	1.7	1.8	1.7	1.8	1.6	1.9	0.0	1.4	1.4	1.8	0.2	1.0	1.6
Diastolic blood pressure, automated reading	1.9	5.9	11.1	1.4	2.8	2.5	3.0	2.5	3.3	2.2	1.5	2.2	2.7	2.8	2.7	3.0	3.1	2.4	1.1	1.8	3.1	2.7	1.5	1.8	2.9
Pain all over the body in last month	1.8	1.9	4.6	0.2	1.5	1.9	1.4	1.8	-0.3	1.7	1.6	1.6	1.8	1.7	1.2	1.5	1.6	1.4	2.2	-0.2	1.1	0.9	-0.4	-1.0	1.8
Arm fat percentage (right)	1.8	7.1	13.9	-0.9	3.4	2.9	2.8	2.9	2.3	2.5	2.0	2.3	2.5	2.6	3.7	3.6	3.0	2.7	1.4	3.0	3.3	3.3	1.2	2.7	2.6
Pulse rate	1.8	3.1	6.7	-0.3	1.1	1.8	2.1	1.9	0.0	2.2	1.9	2.5	1.6	2.4	2.2	1.4	1.1	2.5	0.9	1.8	2.2	2.6	0.7	0.8	1.9
High blood pressure (siblings)	1.8	2.6	10.0	3.2	1.4	1.0	2.0	0.7	1.8	0.7	0.7	0.7	1.5	0.7	2.7	1.3	1.7	1.0	1.4	3.0	1.9	1.5	1.4	0.9	1.6
Number of self-reported non-cancer illnesses	1.8	3.2	6.6	1.8	2.1	1.8	2.6	2.1	1.6	1.5	1.1	1.5	2.3	2.2	1.9	2.3	2.6	1.4	1.1	1.6	1.9	1.6	0.7	0.7	2.3
Medication: Blood pressure	1.8	3.4	7.1	0.6	2.0	2.2	2.5	2.1	0.8	2.1	2.3	2.7	2.0	2.0	1.7	2.2	2.0	2.2	1.4	1.3	1.8	2.3	0.0	0.0	2.1
Systolic blood pressure, automated reading	1.7	4.9	15.2	2.1	2.6	1.9	2.6	2.1	3.9	1.6	1.0	1.3	2.3	2.1	2.9	2.6	2.8	1.7	1.2	2.4	3.2	2.0	1.2	1.8	2.4
Vitamin and mineral supplements	1.7	2.3	5.2	1.5	-2.0	-1.9	-1.4	-2.0	-2.0	-1.8	-1.5	-2.0	-1.5	-2.3	-1.6	-2.1	-1.7	-1.6	-0.1	-0.5	-0.4	-1.4	0.3	0.3	-1.6
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	5.3	1.3	1.9	1.9	2.3	1.1	1.9	1.7	2.0	1.6	2.2	0.9	2.0	1.9	2.1	1.3	1.0	1.7	1.1	1.4	0.5	-0.3	1.9
Medication: Aspirin	1.7	2.2	4.1	1.5	1.9	1.7	1.6	1.4	1.9	1.6	1.7	1.2	2.0	1.3	0.9	1.6	2.0	1.2	1.6	1.0	1.5	1.0	1.5	0.7	1.9
Tinnitus: Yes, now most or all of the time	1.7	2.0	10.1	-0.7	1.7	1.5	0.6	2.6	0.3	1.5	1.0	0.9	1.4	1.5	1.1	1.5	1.6	1.4	3.2	-0.1	1.8	1.0	-0.5	0.0	1.6
Ever smoked	1.7	2.9	8.4	1.1	2.1	1.8	2.1	2.1	0.2	1.4	1.8	1.5	1.9	1.9	1.1	1.7	2.1	1.5	2.9	1.7	1.3	1.7	1.7	0.7	2.1
Leg fat percentage (left)	1.7	6.0	11.0	-0.4	2.9	2.7	2.9	2.6	1.8	2.4	2.3	2.5	2.3	2.4	3.3	3.0	2.7	2.7	1.1	2.6	2.9	3.3	1.1	2.6	2.5
Number of operations (self-reported)	1.7	2.5	4.5	1.4	1.5	1.7	2.0	1.8	0.7	1.9	1.2	1.5	1.9	2.0	1.9	1.5	1.6	2.1	1.6	1.6	1.6	1.6	0.2	0.1	1.9
Schizophrenia (2018)	1.6	3.4	7.0	-0.6	-1.8	-2.1	-2.3	-2.1	0.2	-2.0	-1.9	-2.0	-2.0	-2.0	-1.9	-1.8	-1.9	-2.2	-2.6	-1.6	-1.2	-2.4	-1.3	-1.8	-2.2
Respiratory disease	1.6	3.6	6.6	1.7	1.7	1.9	2.6	2.1	1.0	2.1	1.9	2.1	2.1	2.4	2.1	1.7	1.9	2.4	2.1	1.9	1.5	2.6	1.0	0.4	2.2
Impedance of leg (left)	1.6	7.8	13.6	0.7	-3.3	-3.7	-2.5	-3.5	-0.6	-3.5	-3.5	-3.4	-2.9	-3.1	-1.9	-3.6	-3.0	-3.4	-2.2	-0.5	-2.7	-3.2	-2.5	-2.3	-3.2
Number of incorrect matches in round	1.6	2.6	6.0	-0.7	-1.8	-1.9	-1.6	-1.8	-1.0	-1.9	-1.8	-2.4	-1.9	-2.4	-1.0	-1.9	-1.9	-1.7	-1.0	-1.5	-0.9	-1.5	-1.3	-1.2	-1.9
Glaucoma (self-reported)	1.6	1.8	15.6	-2.8	-1.0	-0.9	-1.4	-0.6	-3.9	-0.7	-0.2	-0.5	-1.4	-0.8	-0.3	-0.9	-1.4	-0.9	-0.3	-0.3	-0.9	-0.7	-1.9	-0.8	-1.3
Shortness of breath walking on level ground	1.6	1.9	4.8	0.4	2.2	1.5	1.6	1.9	1.2	1.1	1.2	0.9	1.6	1.6	1.3	2.0	2.2	0.8	1.6	1.1	1.1	1.1	0.5	-1.1	1.4
Fractured/broken bones in last 5 years	1.6	2.1	4.4	-1.5	-1.6	-1.6	-1.9	-1.6	-0.4	-1.4	-1.6	-1.7	-1.8	-1.4	-0.8	-1.7	-1.9	-1.4	-1.9	-1.4	-1.1	-1.4	-0.3	0.1	-2.1
Hypothyroidism (self reported)	1.5	3.5	5.9	0.6	2.3	2.0	2.4	2.3	2.1	1.9	2.0	2.0	2.2	2.2	0.5	2.3	2.4	1.7	2.2	0.8	1.5	1.9	1.4	-0.5	2.3
Fed-up feelings	1.5	2.7	6.1	2.0	1.1	1.3	2.4	0.8	0.7	1.4	1.2	1.5	1.9	1.1	1.9	1.2	1.6	1.7	1.1	2.5	2.1	2.0	2.0	2.3	1.8
Stomach or abdominal pain in last month	1.5	1.9	4.7	0.7	1.9	1.5	1.8	1.4	1.7	1.3	1.9	1.4	1.8	1.1	1.0	1.6	2.2	0.9	1.6	1.3	0.7	0.9	-0.4	-0.0	1.6
Body fat percentage	1.5	5.8	11.5	-0.1	2.9	2.4	2.8	2.4	2.1	2.1	1.8	2.0	2.2	2.3	3.4	3.1	2.7	2.4	1.0	3.1	3.1	3.2	1.2	2.8	2.3
Eye problems/disorders: None of the above	1.5	1.7	8.4	2.9	0.5	0.5	1.3	0.1	1.5	0.2	0.5	0.3	0.7	0.1	1.7	0.4	0.8	0.2	1.1	2.0	1.5	0.7	2.9	2.3	0.6
Arm fat percentage (left)	1.5	5.8	11.3	-1.0	3.1	2.6	2.6	2.6	1.9	2.2	1.9	2.2	2.2	2.4	3.4	3.3	2.7	2.4	0.8	2.9	3.0	3.1	1.1	2.7	2.3
Medication: Aspirin	1.5	2.0	4.2	1.6	1.9	1.5	1.4	1.3	1.9	1.3	1.5	1.0	1.8	1.1	0.9	1.7	2.1	0.9	1.3	1.1	1.6	0.7	1.3	0.7	1.6
Ever taken oral contraceptive pill	1.5	1.7	4.0	-0.1	1.0	1.7	1.7	1.2	0.8	1.9	2.0	1.8	1.6	1.6	0.1	1.1	1.0	2.0	0.3	0.1	-0.1	2.0	-0.6	-1.1	1.4
Average weekly beer plus cider intake	1.5	2.2	4.9	0.7	-2.2	-2.1	-1.2	-2.0	1.0	-2.0	-1.7	-1.5	-1.6	-1.5	-0.8	-2.0	-1.6	-1.8	-1.7	0.4	-1.5	-1.1	-0.4	0.3	-1.6
Risk taking	1.5	2.2	4.8	1.9	1.0	1.4	2.2	1.3	0.8	1.7	1.7	1.6	1.9	1.7	0.3	1.0	1.5	1.9	1.2	0.5	1.0	2.1	2.1	1.0	1.9
Trunk fat percentage	1.4	5.5	10.4	0.1	2.9	2.3	2.8	2.4	2.0	1.9	1.6	1.9	2.1	2.2	3.2	3.0	2.6	2.3	0.8	3.0	3.2	3.2	1.5	3.0	2.2
High blood pressure (mother)	1.4	1.9	3.4	1.4	1.7	1.6	1.7	1.6	0.8	1.4	1.4	1.3	1.7	1.2	0.9	1.7	1.8	1.4	1.8	0.8	1.6	1.4	0.7	0.1	1.7
Mouth/teeth dental problems: Dentures	1.4	2.4	7.8	1.6	1.6	1.2	2.0	1.8	1.8	0.9	1.4	1.1	1.6	1.4	1.6	1.5	2.1	0.6	2.2	1.7	2.8	0.8	1.0	0.8	1.6
Ever highly irritable/argumentative for 2 days	1.4	1.7	6.0	1.0	1.5	1.3	0.9	1.2	1.9	1.1	1.1	1.1	1.4	0.4	2.4	1.4	1.5	0.9	1.8	1.9	1.5	0.6	-0.3	-0.2	1.4
Headache pain in last month	1.4	2.4	4.9	-1.3	2.2	1.9	1.4	1.8	1.9	1.4	0.9	0.9	1.4	1.5	2.1	1.9	1.7	1.4	1.5	2.2	1.8	1.5	-0.4	0.6	1.5
Medication: Allopurinol	1.4	1.9	4.6	1.1	-1.6	-1.8	-1.2	-1.5	0.5	-1.9	-1.9	-2.1	-1.4	-1.7	-1.0	-1.8	-1.4	-1.8	-0.6	-0.4	0.1	-1.6	-0.6	-0.6	-1.5
Medication: Lisinopril	1.4	1.9	3.7	0.3	1.4	1.6	1.6	1.2	1.0	1.9	1.7	1.8	1.7	1.2	1.5	1.4	1.4	1.9	1.2	1.2	0.6	1.5	-0.2	0.9	1.6
Bipolar Disorder or Schizophrenia	1.3	3.3	5.6	-0.5	-1.9	-1.9	-2.1	-1.9	-0.7	-1.7	-1.6	-1.9	-1.8	-1.9	-2.3	-2.0	-1.9	-2.0	-1.8	-2.0	-1.4	-2.3	-1.5	-2.4	-2.0
Impedance of leg (right)	1.3	6.1	11.6	0.8	-2.9	-3.4	-2.2	-3.0	-0.5	-3.3	-3.4	-3.1	-2.5	-2.6	-1.4	-3.1	-2.4	-3.2	-1.6	0.2	-2.2	-3.2	-2.2	-2.2	-2.7
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	5.4	1.4	1.7	1.9	2.2	1.8	0.1	1.8	2.2	2.0	1.8	2.0	1.1	1.8	1.7	2.0	1.0	1.7	2.1	2.3	2.0	0.3	1.9
Noisy workplace	1.3	1.5	4.1	-0.0	1.6	1.3	1.4	1.1	2.0	1.1	0.7	1.0	1.2	1.1	1.6	1.6	1.5	1.4	0.8	1.1	0.9	1.6	0.2	1.7	1.2
Depression (self-reported)	1.3	1.5	5.9	0.6	1.1	0.9	1.2	0.9	1.4	0.7	0.9	1.0	0.8	0.3	1.6	1.2	1.0	0.8	0.2	1.5	2.2	1.5	2.0	2.4	0.8
Standing height	1.3	12.9	24.9	4.1	3.4	3.6	4.7	3.3	1.2	3.9	4.2	4.0	3.9	3.4	2.5	3.4	3.5	4.3	3.2	3.1	3.3	5.0	3.8	3.4	3.9
Worry too long after embarrassment	1.3	2.2	6.2	-2.1	-1.5	-1.3	-2.0	-0.8	-2.5	-1.2	-1.7	-1.3	-1.4	-0.8	-2.0	-1.3	-1.5	-1.7	-1.1	-2.0	-0.1	-2.3	-0.4	0.0	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	5.2	1.3	0.8	1.4	1.4	1.4	0.8	1.6	1.0	1.3	1.6	1.7	0.6	0.8	1.0	1.7	1.6	0.2	1.0	1.4	2.3	0.7	1.7
Health satisfaction	1.3	1.7	4.3	1.4	1.5	1.4	1.7	1.1	2.1	1.4	1.3	1.1	1.8	1.1	0.6	1.5	1.6	1.3	0.7	1.4	0.7	1.3	1.2	-0.6	1.5
Eye problems/disorders: Cataract	1.3	1.5	6.6	-2.6	-0.3	-0.3	-0.7	-0.2	-1.8	-0.0	-0.2	0.1	-0.5	0.2	-2.1	-0.2	-0.5	0.0	-1.8	-2.1	-2.0	-0.2	-2.2	-1.8	-0.5
Osteoarthritis (self-reported)	1.3	1.7	3.2	1.3	1.4	1.5	1.6	1.5	-0.6	1.5	1.4	1.6	1.7	1.7	0.4	1.4	1.6	1.6	1.5	-0.1	0.4	1.5	1.0	-0.4	1.8
Irritability	1.3	2.2	6.2	2.0	1.1	1.2	1.8	0.9	1.4	1.3	1.8	1.3	1.6	0.8	1.8	0.9	1.3	1.2	2.0	2.5	0.6	1.7	2.0	1.1	1.6
Lupus	1.2	1.8	3.6	-1.4	-0.9	-1.1	-1.5	-1.4	-1.5	-1.0	-1.5	-1.6	-1.2	-1.3	-1.9	-1.0	-1.2	-1.1	-1.2	-1.7	-1.9	-1.4	-1.5	-0.8	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	5.1	-0.3	1.9	2.2	1.8	2.2	0.3	2.1	1.9	1.9	1.8	2.3	0.9	2.1	1.7	2.2	1.3	0.7	1.6	2.1	0.7	-0.1	2.0
Birth weight	1.2	2.6	7.2	1.7	1.6	1.5	2.2	1.4	1.2	1.5	2.0	1.4	1.7	0.8	1.8	1.5	1.7	1.7	2.7	1.6	1.5	2.0	1.5	0.1	1.7
Supplements: Calcium	1.2	1.3	4.0	-2.0	-1.1	-1.0	-1.6	-0.6	0.4	-1.1	-2.0	-1.0	-1.3	-0.7	0.1	-1.0	-1.1	-1.1	-0.9	-1.1	-1.0	-1.6	-1.0	-1.1	-1.1
Alcohol drinker status: Previous	1.2	1.4	4.0	-1.1	2.0	1.5	1.0	1.5	-0.1	1.4	1.3	1.1	1.1	1.3	-1.2	1.9	1.5	1.1	0.3	-1.3	0.0	0.9	-0.9	-0.7	0.9
Schizophrenia vs Biploar Disorder	1.1	1.4	3.1	-0.4	-0.9	-1.3	-1.3	-1.5	0.5	-1.5	-1.7	-1.5	-1.2	-1.7	-0.8	-0.9	-0.9	-1.4	-1.0	-0.7	-1.4	-1.5	-1.5	-0.8	-1.3
Schizophrenia (2014)	1.1	2.5	5.1	-0.3	-1.6	-1.7	-1.8	-1.7	-0.3	-1.7	-1.8	-1.7	-1.4	-1.5	-1.9	-1.5	-1.5	-1.8	-2.1	-1.9	-1.0	-2.3	-1.4	-1.6	-1.6
Triglycerides	1.1	1.9	6.1	1.5	1.1	1.0	1.7	1.0	0.9	1.1	1.5	1.4	1.2	1.1	2.3	1.2	1.1	1.1	0.3	2.5	1.9	1.5	1.2	1.5	0.9
Emphysema/chronic bronchitis	1.1	1.2	3.7	0.3	1.4	1.1	1.4	1.4	0.6	1.0	0.9	1.1	1.1	1.9	1.1	1.3	1.4	1.1	-0.1	0.8	1.2	1.6	1.2	0.4	0.9
Age at last live birth	1.1	1.6	4.5	-1.5	-1.4	-0.9	-2.1	-0.9	-1.5	-0.9	-1.5	-1.6	-1.5	-1.0	-0.9	-1.4	-1.8	-1.0	-1.4	-1.7	-0.2	-1.4	0.4	0.4	-1.4
Medication for cholesterol	1.1	1.7	3.7	-0.7	-1.3	-1.6	-1.9	-1.4	0.2	-1.5	-1.7	-1.8	-1.5	-1.6	-0.5	-1.4	-1.3	-1.5	-1.1	-0.6	-1.0	-1.7	-0.8	0.1	-1.4
Medication: Gliclazide	1.1	1.3	3.3	1.5	1.2	0.9	1.8	0.7	1.8	0.8	1.0	1.0	1.1	0.7	1.0	1.1	1.3	1.2	1.5	1.0	0.4	1.6	0.4	0.8	1.2
Illnesses of father: None of the above (group 1)	1.1	1.4	4.7	0.1	-0.5	-1.3	-1.7	-1.1	-0.4	-1.6	-2.0	-1.7	-1.1	-1.4	-1.0	-0.7	-0.6	-1.9	-0.8	-0.4	-0.1	-2.2	-0.2	-0.6	-1.2
Ulcerative Colitis	1.0	1.5	5.0	-0.9	-1.4	-1.2	-1.8	-1.2	-2.2	-1.1	-1.8	-1.4	-1.0	-1.4	-0.8	-1.3	-1.2	-1.1	-0.1	-1.2	-0.7	-1.6	-0.2	-0.2	-1.1
Townsend deprivation index at recruitment	1.0	1.4	4.2	2.0	1.0	0.8	1.7	0.6	0.7	0.6	0.6	0.5	1.1	0.6	1.3	0.9	1.2	0.8	1.5	1.3	1.8	1.1	1.6	2.0	1.2
Current tobacco smoking	1.0	1.6	3.8	1.6	1.3	1.0	1.9	1.1	-0.1	0.9	1.4	1.4	1.3	1.1	1.3	1.2	1.6	1.1	1.5	1.6	1.3	1.6	1.1	0.7	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	5.7	1.5	1.2	0.9	1.5	0.4	1.1	0.6	1.0	0.6	1.4	0.2	2.3	1.1	1.6	0.3	1.3	2.4	1.0	0.6	0.6	0.6	1.2
Taking other prescription medications	1.0	1.5	2.6	0.8	1.6	1.3	1.5	1.5	1.2	0.9	1.1	0.9	1.3	1.5	1.0	1.5	1.6	0.8	1.3	1.1	1.5	1.3	0.8	1.3	1.3
Qualifications: None of the above	1.0	2.1	7.1	2.3	1.4	0.8	2.7	0.9	2.1	0.4	1.0	1.1	1.5	0.8	1.1	1.4	2.1	0.7	1.7	2.0	1.8	1.4	-0.4	0.4	1.5
Financial difficulties in last 2 years	1.0	1.3	4.8	1.8	0.9	0.9	1.5	0.5	1.1	0.9	0.9	0.6	1.3	0.8	1.1	0.7	1.1	0.8	0.7	1.8	1.0	0.9	2.2	1.4	1.1
Prospective memory result	1.0	1.3	3.2	0.6	1.7	1.1	1.1	1.3	0.6	0.8	0.6	0.9	1.2	1.3	1.7	1.8	1.8	0.8	1.3	1.4	0.3	0.6	0.0	0.5	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	3.4	1.2	1.6	1.4	1.9	1.4	0.4	1.0	1.0	0.9	1.5	1.0	-0.3	1.5	1.7	1.1	1.1	0.1	1.3	1.3	1.4	-0.8	1.6
Hair/balding pattern: Pattern 4	1.0	2.4	5.1	-1.3	2.0	1.9	1.1	2.3	-0.3	1.9	1.9	2.1	1.4	1.6	0.1	2.1	1.7	1.8	2.0	-1.0	1.6	1.4	0.3	0.3	1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.3	-0.4	1.4	1.2	0.7	1.3	0.4	1.0	0.3	1.0	1.0	1.5	1.3	1.5	1.3	1.0	0.5	0.5	1.0	0.9	1.0	1.3	1.2
Wears glasses or contact lenses	1.0	1.1	2.1	0.2	1.2	1.3	1.0	1.4	0.6	1.4	1.3	0.9	1.2	1.4	0.1	1.1	1.1	1.2	0.9	0.4	1.3	1.2	1.4	0.6	0.9
Medication: Atorvastatin	1.0	1.2	5.9	0.8	0.9	0.9	1.5	0.7	1.0	1.0	0.7	0.6	1.1	1.4	1.7	0.8	0.9	1.1	-0.1	2.4	1.2	1.3	0.4	1.3	1.0
Alzheimer’s Disease (in father)	0.9	1.0	3.1	-0.8	-0.9	-0.6	-1.5	-0.8	-1.8	-0.5	-1.0	-0.9	-0.7	-1.0	0.3	-0.9	-0.9	-0.8	0.1	-0.8	-0.4	-1.6	-1.4	-1.7	-0.8
Alzheimer’s Disease (including proxy)	0.9	1.3	3.5	-0.5	-1.6	-1.0	-1.6	-1.2	-1.9	-0.5	-0.6	-0.9	-1.1	-1.6	-0.1	-1.7	-1.7	-0.8	0.0	-0.8	-0.7	-1.2	-1.1	-1.1	-1.3
Crohns Disease (2017)	0.9	2.1	5.7	1.5	1.3	1.5	1.0	1.3	-0.6	1.4	1.0	1.3	1.9	1.4	2.4	1.3	1.8	1.0	1.4	2.2	1.6	0.6	1.7	1.0	1.7
Medication: Levothyroxine sodium	0.9	1.5	4.0	0.3	1.5	1.2	1.3	1.6	1.8	1.0	0.8	1.1	1.4	1.4	0.8	1.5	1.7	1.0	2.0	1.1	0.7	0.9	0.6	-0.6	1.6
Hair/balding pattern: Pattern 3	0.9	1.4	3.0	-0.0	-1.4	-1.4	-1.3	-1.6	-0.4	-1.4	-1.6	-1.5	-1.2	-1.2	-0.8	-1.4	-1.2	-1.3	-1.7	0.1	-1.1	-1.1	0.6	0.2	-1.4
Overall health rating	0.9	1.8	4.4	-0.3	2.1	1.6	1.8	1.5	0.4	1.4	1.3	1.1	1.6	1.2	1.4	2.0	1.9	1.4	0.8	1.1	0.4	1.6	-0.9	-1.0	1.6
Long-standing illness, disability or infirmity	0.9	1.4	3.3	1.5	1.6	1.3	1.6	1.1	1.6	1.1	0.8	0.8	1.7	1.2	0.6	1.4	1.8	1.0	0.9	1.0	0.0	1.1	-0.1	-0.2	1.5
Body Mass Index (BMI) (2010)	0.8	1.1	2.7	0.2	0.7	0.5	1.5	0.8	0.3	0.4	0.5	0.9	0.4	1.4	1.1	1.0	0.7	0.9	-1.2	1.6	1.6	1.6	1.4	1.6	0.6
Lung FEV1/FVC ratio	0.8	4.2	11.8	-3.4	-1.4	-1.8	-3.1	-1.4	-1.1	-2.1	-2.4	-2.2	-2.3	-1.5	-1.5	-1.1	-1.8	-2.2	-3.1	-1.4	-1.1	-2.5	-2.2	-1.9	-2.4
Supplements: Zinc	0.8	0.9	2.3	0.5	1.1	1.2	1.1	1.2	-0.3	1.1	1.3	1.5	1.0	1.2	-0.3	1.2	1.0	1.0	0.3	-0.2	0.8	0.9	1.2	0.6	1.0
Severe depression (siblings)	0.8	0.9	3.1	1.2	1.0	1.0	0.9	1.3	-0.6	0.9	0.1	0.0	1.5	1.3	-0.1	0.9	1.4	1.0	1.7	-0.8	0.2	0.6	0.6	-0.3	1.4
Had other major operations	0.8	1.0	4.2	0.7	0.6	0.8	1.0	1.0	-0.1	1.0	0.5	0.9	0.9	1.2	1.6	0.7	0.8	1.2	0.5	1.1	1.1	1.1	1.0	2.0	1.0
Happiness	0.8	0.9	3.3	1.2	-1.2	-1.4	-0.4	-1.6	-0.1	-1.3	-0.8	-0.8	-1.0	-1.8	-0.3	-1.2	-1.0	-1.0	-0.5	0.7	-0.2	-0.6	0.5	0.6	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.6	-0.5	-0.7	-0.9	-0.9	-0.9	-0.0	-1.0	-1.2	-1.5	-0.8	-1.3	-0.3	-1.1	-0.7	-1.0	0.6	-1.1	-1.2	-0.9	-1.6	-0.9	-0.9
Number of full brothers	0.8	1.0	2.5	0.1	-0.8	-0.9	-0.6	-1.6	0.2	-1.1	-1.1	-1.6	-0.7	-1.5	-1.1	-1.0	-0.7	-0.9	-1.2	-0.8	-1.3	-1.0	-1.2	-0.2	-0.9
Pulse rate, automated reading	0.8	2.5	10.2	0.2	0.9	1.0	1.7	1.2	-0.3	1.2	1.4	1.9	1.0	1.8	2.8	1.1	1.0	1.5	0.1	3.2	1.6	2.4	1.3	2.3	1.2
Smoking status: Current	0.8	1.2	3.3	1.7	1.1	0.7	1.8	0.8	0.1	0.6	1.2	1.1	1.0	0.8	1.1	0.9	1.3	0.8	1.4	1.4	1.2	1.4	1.2	0.9	1.1
Eye problems/disorders: Glaucoma	0.8	1.0	6.8	-1.4	-1.0	-1.0	-1.2	-0.8	-2.6	-0.9	-0.3	-0.6	-1.1	-1.0	0.0	-1.0	-1.1	-1.0	-0.2	0.4	-0.2	-0.7	-0.9	-0.2	-1.0
Cholesterol lowering medication	0.8	1.2	4.1	0.9	1.3	1.3	1.7	0.7	0.4	0.8	1.2	0.9	1.4	0.8	1.2	1.2	1.5	0.7	0.6	1.4	0.3	1.0	-0.5	-2.0	1.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.1	0.5	1.6	0.9	1.0	0.5	0.9	0.3	0.4	-0.1	1.1	0.0	1.8	1.2	1.6	0.1	1.6	2.0	0.9	0.4	0.4	0.4	1.0
Diabetes (mother)	0.7	0.9	3.3	1.6	0.7	0.8	1.4	0.3	0.2	0.8	0.5	0.5	1.0	0.7	1.4	0.7	0.8	0.9	0.6	1.8	0.9	1.0	0.9	1.0	0.8
Average weekly fortified wine intake	0.7	0.8	2.1	0.1	0.7	1.0	1.2	0.9	0.5	1.1	1.4	0.8	1.0	0.6	1.4	0.6	0.7	1.1	1.0	0.7	1.1	1.2	0.4	0.9	0.9
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	3.3	0.4	-0.8	-0.8	-0.4	-0.6	0.8	-0.9	-0.7	-0.6	-0.6	-0.7	-0.1	-0.9	-0.6	-0.7	0.8	0.4	-1.8	-0.8	-1.2	-1.8	-0.4
Time employed in main current job	0.7	0.8	3.0	-0.3	-1.0	-0.8	-1.4	-0.8	-1.7	-0.6	-0.5	-0.6	-0.9	-0.9	-0.9	-0.9	-1.1	-0.7	-0.9	-0.2	-1.0	-1.2	-0.6	-0.1	-1.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	5.4	-2.3	-1.1	-0.9	-1.0	-1.0	-1.4	-0.9	-0.5	-0.4	-1.3	-1.1	-1.3	-1.1	-1.3	-0.6	-0.3	-1.0	-1.9	-0.4	-1.1	-0.9	-1.0
Medication: Amlodipine	0.7	1.0	2.9	1.1	0.9	0.7	1.4	0.8	1.1	0.8	0.9	1.1	0.8	1.2	0.2	1.1	1.0	1.2	-0.3	0.9	1.1	1.7	1.6	0.8	1.0
Wheeze or whistling in the chest in last year	0.7	1.2	2.8	0.1	1.0	1.1	1.6	1.2	-0.8	1.1	1.6	1.7	1.2	1.0	1.6	1.1	1.3	1.0	1.2	0.8	0.9	1.3	0.1	0.8	1.0
Supplements: Vitamin C	0.7	0.8	2.0	-1.4	1.4	1.2	0.4	0.9	1.1	1.0	0.2	0.5	0.9	0.7	0.5	1.4	1.1	0.9	0.7	-0.1	-0.6	0.4	-1.2	0.2	0.9
Average weekly red wine intake	0.7	1.0	3.3	-1.4	0.9	1.3	0.5	1.5	0.4	1.4	1.3	1.3	0.7	1.2	0.1	0.9	0.5	1.4	1.8	-0.2	0.5	0.9	-0.1	-0.4	1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.9	0.6	1.1	1.0	1.2	0.9	0.6	0.8	0.5	1.1	1.0	1.2	1.4	1.3	1.1	1.1	0.0	0.6	1.1	0.8	0.6	-0.3	1.1
Ulcerative Colitis (UC)	0.6	1.1	4.9	-0.3	-1.2	-1.1	-1.4	-1.0	-2.2	-0.9	-1.2	-0.8	-0.8	-1.2	-0.9	-1.1	-0.9	-1.1	-0.0	-1.0	-0.6	-1.5	0.3	-0.5	-0.9
Mean Putamen Volume	0.6	0.7	2.5	0.0	-0.4	-1.0	-0.8	-0.8	0.4	-1.5	-0.9	-1.2	-1.0	-1.0	-1.4	-0.7	-0.5	-1.6	-0.3	-0.3	-0.5	-1.0	-0.2	-0.6	-1.0
HbA1C	0.6	0.7	4.3	2.1	-0.0	-0.1	0.8	-0.1	-0.2	-1.2	0.9	0.4	-0.6	-0.1	0.8	-0.1	0.3	-0.7	0.7	1.2	0.3	0.3	2.0	0.9	0.6
Maternal smoking around birth	0.6	0.8	1.6	0.8	1.1	0.9	1.2	0.8	1.3	0.9	0.6	0.6	1.0	0.7	1.1	1.1	1.1	0.9	0.1	1.1	1.1	0.9	0.1	-1.0	1.0
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.8	-1.2	0.7	0.7	0.4	0.7	1.5	0.5	-0.3	0.1	0.6	0.8	-0.2	0.9	0.8	0.4	-0.2	-1.2	-0.3	-0.2	-2.0	-1.7	0.7
Falls in the last year	0.6	0.8	2.0	1.1	0.6	0.9	1.2	0.7	0.5	0.9	0.7	0.9	1.1	0.8	1.2	0.8	0.9	0.9	0.3	1.4	1.3	0.9	0.1	0.0	1.0
Medication: Lansoprazole	0.6	0.7	1.5	1.1	1.2	0.8	1.1	1.0	-0.5	0.7	1.0	0.5	1.0	0.9	0.6	0.9	1.2	0.6	0.9	0.4	0.7	0.8	0.5	-0.2	0.9
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.9	0.7	1.4	1.1	1.2	1.2	2.0	0.9	0.7	0.7	1.4	1.0	0.3	1.4	1.6	0.8	1.6	0.7	0.0	0.7	0.7	-0.6	1.4
Medication: Blood pressure	0.6	1.0	4.4	2.1	0.8	0.6	0.9	0.5	2.1	0.7	0.3	0.2	1.0	0.7	1.6	0.8	0.9	0.5	-0.2	1.3	1.5	0.4	0.5	0.7	0.7
Commuting to job workplace: Car/motor vehicle	0.6	0.7	4.4	1.4	0.5	0.4	1.0	0.7	-0.5	0.6	0.6	1.0	0.9	0.9	-0.4	0.5	0.8	0.8	0.5	0.4	-0.4	0.5	0.8	-2.1	0.8
Major Depression (MDD)	0.5	0.6	3.2	-1.8	0.4	0.5	0.4	0.7	-1.6	0.7	0.4	0.3	0.3	0.4	-0.5	0.5	0.3	0.9	0.8	-1.4	-0.2	0.9	-0.8	-0.4	0.3
Prostate Cancer	0.5	0.8	2.9	-0.4	-0.7	-0.6	-0.6	-0.9	-0.3	-0.7	-0.4	-0.9	-0.6	-1.1	-0.8	-0.9	-0.7	-0.9	0.2	-1.3	-1.4	-1.1	-1.1	-1.7	-0.7
LDL Cholesterol	0.5	0.7	1.8	1.0	1.2	1.2	0.7	1.0	0.3	0.9	0.1	0.1	1.2	1.0	0.4	1.0	1.1	0.8	1.4	-0.3	0.6	-0.1	0.5	-1.2	1.1
Primary Biliary Cirrhosis	0.5	0.8	2.1	0.2	-1.0	-0.9	-0.4	-1.1	0.2	-0.7	-0.4	-1.2	-0.6	-1.5	-0.6	-1.1	-0.8	-1.0	-0.2	-1.2	-0.7	-1.0	-1.1	-1.2	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.6	0.4	0.9	0.6	0.6	1.0	1.3	0.4	0.2	0.6	0.7	1.0	1.2	0.9	0.9	0.2	0.4	1.1	1.2	0.2	0.9	-0.2	0.6
Blood White Count	0.5	3.4	11.1	1.8	1.9	1.5	2.3	1.5	2.9	1.3	1.5	1.4	2.1	1.6	2.2	1.6	2.3	1.1	1.4	3.3	1.8	1.6	1.3	1.1	1.9
Waist Hip Ratio (WHR)	0.5	2.0	6.4	1.4	1.5	1.1	1.9	1.1	2.3	1.0	0.7	1.3	1.6	1.5	2.3	1.6	1.8	1.0	0.7	2.5	1.1	0.9	0.2	-0.1	1.5
Chronic bronchitis/emphysema (father)	0.5	0.6	1.8	0.2	-1.0	-0.9	-0.0	-0.8	0.7	-0.7	-0.5	-0.7	-0.7	-0.7	-1.3	-1.1	-0.9	-0.4	0.5	-1.2	-1.2	-0.3	-0.8	0.1	-0.7
Past tobacco smoking	0.5	0.9	4.8	-0.8	-1.1	-0.8	-1.1	-1.2	0.1	-0.6	-0.9	-0.5	-0.9	-1.0	-0.1	-0.7	-1.1	-0.6	-2.2	-0.4	-0.7	-0.9	-1.7	-0.2	-1.2
Medication: Cholesterol lowering	0.5	0.8	4.3	2.1	1.2	0.8	0.8	0.9	-0.1	0.8	0.8	0.4	1.2	1.1	0.8	1.0	1.3	0.3	0.7	0.7	1.3	0.1	0.5	-0.1	1.0
Loud music exposure frequency	0.5	0.5	3.8	-0.5	-0.5	-0.5	-0.4	-0.1	0.9	-0.6	-0.4	-0.2	-0.7	-0.4	-1.0	-0.5	-0.4	-0.3	0.6	-1.9	-0.9	-0.3	-0.7	-1.6	-0.3
Migraine (self-reported)	0.5	0.6	6.2	-0.9	0.1	0.2	-0.4	0.1	-0.6	0.0	-0.0	-0.2	-0.1	-0.0	-1.5	0.1	-0.2	-0.2	0.7	-1.8	-0.7	-0.6	-0.5	-2.5	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	3.0	0.1	-0.8	-0.4	-0.4	-0.7	-1.7	-0.2	0.0	-0.7	-0.3	-0.6	-1.0	-0.9	-0.7	-0.5	-0.4	-1.6	-1.2	-0.7	0.4	-1.4	-0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	4.2	-2.1	-0.5	-0.2	-1.2	0.0	-0.9	-0.1	0.1	0.3	-0.9	0.0	-0.8	-0.3	-1.0	-0.2	-1.4	-1.1	-0.3	-0.5	-0.5	0.2	-0.6
Diabetes diagnosed by doctor	0.5	0.8	4.2	-0.6	1.6	1.0	0.7	0.7	2.0	0.6	-0.1	0.1	0.9	0.9	0.8	1.5	1.4	0.6	-0.4	0.2	0.4	0.4	-1.0	-0.6	0.9
Friendships satisfaction	0.5	0.6	1.7	-1.0	1.2	0.7	0.6	0.9	0.6	0.2	0.3	0.3	0.4	0.5	1.3	1.0	1.0	0.3	1.2	1.2	0.4	0.7	-0.7	-0.2	0.8
Asthma (self-reported)	0.5	0.9	1.9	0.0	0.9	1.0	1.3	1.2	0.2	1.1	1.1	1.4	0.9	1.1	1.0	1.1	1.0	1.2	1.2	0.7	0.6	1.3	-0.1	0.3	1.0
Commuting to job workplace: Public transport	0.5	0.6	5.0	-2.1	0.2	0.3	-0.7	0.5	-1.0	0.3	-0.1	0.0	-0.4	0.1	0.9	0.2	-0.3	0.4	0.3	0.2	1.0	0.5	-0.1	2.2	-0.1
Bipolar Disorder (2018)	0.4	0.6	2.2	-0.1	-0.8	-0.6	-0.6	-0.5	-1.4	-0.3	-0.1	-0.5	-0.4	-0.6	-1.3	-1.0	-0.7	-0.4	0.4	-1.3	-0.7	-0.6	-0.8	-1.5	-0.4
Age at First Birth	0.4	0.6	2.9	-0.2	-0.4	-0.3	-0.7	-0.4	1.6	-0.4	-0.5	-0.5	-0.3	-0.7	-0.4	-0.4	-0.4	-0.7	0.3	-0.8	-1.3	-1.2	-1.7	-1.5	-0.4
Coronary Artery Disease (CAD)	0.4	0.5	1.5	-0.0	-0.7	-1.1	-0.5	-0.6	0.5	-1.0	-1.2	-0.8	-0.5	-0.4	-0.0	-0.7	-0.3	-0.9	0.4	0.8	-0.9	-0.9	-0.1	-0.9	-0.5
Systolic Blood Pressure	0.4	2.1	12.8	2.4	1.2	0.8	1.7	0.7	3.6	0.6	0.3	0.6	1.2	1.0	1.6	1.3	1.5	0.8	-0.2	1.9	2.5	1.1	0.7	1.3	1.1
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.5	0.3	1.2	0.8	1.2	0.5	1.6	0.5	0.3	0.4	0.8	1.0	1.5	1.2	1.2	0.6	-0.7	1.3	0.9	0.8	0.3	-0.5	0.9
Chronotype (morning person)	0.4	0.8	7.0	2.6	-0.6	0.3	0.5	-0.3	-0.2	0.9	1.0	0.7	0.9	-0.3	-0.2	-0.5	-0.1	0.6	1.0	-0.3	1.4	0.1	1.8	1.0	0.7
Average weekly spirits intake	0.4	0.5	1.3	1.0	0.7	0.4	1.1	0.4	0.6	0.5	0.8	0.4	0.6	0.0	0.6	0.5	0.7	0.7	1.1	0.6	1.1	1.0	-0.4	0.3	0.6
Relative age of first facial hair	0.4	0.9	3.8	2.0	-1.1	-1.0	0.2	-1.6	-0.1	-0.8	-1.2	-0.6	-0.2	-0.5	0.4	-0.8	-0.5	-0.7	-1.9	1.8	-0.2	-0.6	0.3	0.6	-0.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	4.3	-2.1	-0.3	-0.1	-0.3	0.2	-0.0	-0.1	-0.2	0.3	-0.3	0.2	-0.2	0.1	-0.3	-0.1	-1.4	-0.3	0.6	-0.1	-1.9	-1.5	-0.2
Medication: Simvastatin	0.4	0.6	3.2	1.5	1.2	0.7	0.6	0.7	-0.2	0.2	0.3	-0.1	0.9	0.5	0.5	1.1	1.4	-0.3	0.6	-0.3	0.5	-0.4	-0.0	-1.8	0.8
Fluid intelligence score	0.4	0.9	2.5	-1.0	-1.3	-0.8	-1.0	-1.1	-1.6	-0.6	-0.8	-0.9	-1.0	-0.9	-0.4	-1.3	-1.4	-0.7	-1.3	-0.4	-0.4	-0.5	0.4	0.8	-1.0
Father’s age at death	0.4	0.5	1.8	-0.5	-1.3	-0.8	-0.9	-0.6	-0.2	-0.6	-0.2	-0.4	-1.1	-0.7	-0.1	-1.3	-1.3	-0.8	0.1	0.3	0.2	-0.5	-0.8	-0.4	-0.9
Qualifications: A levels/AS levels or equivalent	0.4	0.9	7.2	-1.0	-0.3	0.1	-0.9	0.3	-1.9	0.1	0.1	0.4	-0.6	0.4	-1.2	-0.3	-0.7	0.1	-0.3	-1.5	-0.7	0.2	2.7	1.6	-0.3
Asthma	0.4	0.7	1.5	-0.5	1.0	1.0	1.0	1.2	0.2	1.0	1.0	1.2	0.8	1.1	0.7	1.1	0.9	1.0	1.1	0.4	0.5	1.1	-0.5	0.3	0.8
Length of working week for main job	0.4	0.4	1.6	-0.7	0.7	0.4	0.5	1.2	-0.1	0.4	0.5	1.0	0.2	1.1	0.2	0.8	0.6	0.8	0.6	0.4	0.4	1.3	-0.1	-0.2	0.5
Blood clot in the leg (DVT)	0.4	0.5	1.4	0.4	0.8	0.8	1.0	0.7	0.8	0.7	0.4	0.9	0.8	1.1	1.2	1.0	0.9	0.8	-0.2	0.3	0.7	0.5	0.2	-0.6	0.9
Gout (self-reported)	0.4	0.6	4.3	1.0	0.7	0.4	0.9	0.8	1.1	0.2	0.1	0.2	0.6	0.7	0.4	0.7	0.8	0.3	0.4	1.1	2.1	0.6	0.0	0.1	0.6
Comparative body size at age 10	0.4	1.1	2.5	-0.8	1.4	1.2	0.5	1.3	-0.8	1.0	1.4	1.2	0.9	0.6	1.3	1.3	1.1	0.8	1.5	0.7	1.6	0.8	0.2	-0.1	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.8	-0.7	-0.6	-0.4	-0.9	0.0	0.1	-0.4	-1.1	-0.4	-0.3	-0.1	0.3	-0.5	-0.3	-0.6	0.0	-0.4	-0.1	-1.1	-1.3	-1.7	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.8	0.3	0.3	0.4	1.1	0.7	-0.2	0.7	1.0	1.4	0.6	1.0	0.7	0.5	0.6	0.9	0.4	0.5	-0.1	0.8	-0.3	-0.1	0.7
Alcohol intake frequency.	0.4	0.8	3.2	0.0	1.8	1.3	0.8	1.1	1.1	0.8	0.5	0.6	1.1	0.6	0.8	1.8	1.6	0.4	0.8	0.2	0.5	0.3	-0.0	-0.4	0.9
Loneliness, isolation	0.4	0.6	3.9	2.0	0.7	0.1	1.0	0.1	-0.2	-0.0	1.0	0.4	0.7	-0.2	0.0	0.4	1.0	-0.2	1.7	1.2	-0.1	0.3	0.9	-0.4	0.5
High cholesterol (Self-reported)	0.4	0.8	2.5	1.6	1.0	0.9	0.8	0.9	0.0	0.6	0.6	0.3	1.1	0.9	0.9	0.9	1.1	0.3	1.0	0.6	1.5	-0.0	0.1	-1.3	1.1
Ever depressed for a whole week	0.4	0.5	3.1	0.7	-0.2	-0.8	-0.5	-0.2	-0.7	-0.9	-0.8	-0.8	-0.4	-0.6	-1.0	-0.5	-0.1	-0.7	0.8	-0.4	-0.3	-0.7	0.2	-1.8	-0.3
Unable to work because of sickness or disability	0.4	0.5	1.5	0.5	-0.9	-0.8	-0.5	-1.1	0.5	-0.7	-1.0	-1.1	-0.3	-0.7	-0.1	-1.2	-0.6	-0.9	-0.5	0.0	-0.9	-0.8	-0.7	-0.3	-0.7
Pack years of smoking	0.4	0.6	2.5	1.1	0.9	0.4	1.2	0.4	1.6	0.4	1.1	0.7	0.8	0.5	-0.2	0.8	1.1	0.3	0.4	1.1	0.7	0.7	0.3	-0.4	0.6
Neuroticism (Nagel 2018)	0.3	0.7	1.7	-0.1	-0.8	-1.1	-0.9	-1.0	-1.2	-0.9	-1.0	-0.9	-0.7	-1.3	-0.5	-0.9	-0.8	-1.0	-0.2	-0.2	-0.3	-1.0	-0.4	-0.3	-1.0
Alzheimer’s Disease (in mother)	0.3	0.3	1.5	0.7	-1.0	-0.6	-0.2	-0.8	-0.6	-0.2	0.4	-0.3	-0.5	-0.9	-0.1	-1.2	-0.9	-0.3	0.1	0.1	0.1	0.1	0.3	0.1	-0.7
Bipolar Disorder (2011)	0.3	0.3	1.5	1.0	-0.3	-0.3	-0.0	0.0	-0.2	-0.4	-0.2	-0.2	-0.2	0.3	-0.9	-0.4	-0.1	-0.3	0.0	-1.2	-0.9	-0.1	0.4	-1.1	-0.1
Crohns Disease (2012)	0.3	0.4	1.7	0.9	0.3	0.4	0.3	0.3	-0.7	0.6	0.1	0.2	0.9	0.2	1.3	0.3	0.6	0.5	0.8	1.0	1.0	0.1	0.8	1.0	0.7
Rheumatoid Arthritis	0.3	0.4	2.4	1.6	0.2	0.1	0.5	0.4	-0.0	0.2	0.5	0.8	0.3	0.3	1.1	0.1	0.3	0.3	0.6	1.3	0.4	0.7	1.4	0.4	0.5
Blood Eosinophil Count	0.3	2.1	8.2	0.6	1.3	1.3	1.9	0.7	2.0	1.2	1.1	1.2	1.4	1.4	1.7	1.6	1.4	1.2	-0.5	2.9	1.7	1.7	1.2	1.6	1.3
Hearing difficulty/problems: Yes	0.3	0.5	1.8	-0.2	0.8	0.8	0.8	1.2	0.8	0.6	0.5	0.5	0.7	0.9	0.4	0.6	0.9	0.5	1.3	-0.5	0.5	0.5	-0.6	-0.9	0.7
Medication for hormone replacement therapy	0.3	0.3	3.1	0.1	0.0	0.3	0.2	0.5	0.0	0.5	0.5	0.6	0.1	0.6	-0.1	0.1	0.0	0.4	0.6	-0.4	0.4	0.4	1.3	1.8	0.2
Medication: Metformin	0.3	0.4	1.5	-0.5	0.8	0.8	0.3	0.6	0.8	0.5	-0.1	0.1	0.6	0.8	1.2	0.8	0.8	0.5	0.2	0.8	-0.1	0.3	-0.6	-0.1	0.7
Pack years adult smoking proportion	0.3	0.5	2.2	0.9	0.8	0.3	1.1	0.4	1.5	0.3	0.9	0.6	0.7	0.4	0.1	0.7	1.0	0.2	0.2	1.2	0.8	0.6	0.3	-0.3	0.5
Qualifications: CSEs or equivalent	0.3	0.4	2.6	-0.7	-0.0	-0.0	-0.1	-0.2	1.3	-0.2	-0.6	-0.1	-0.0	0.1	1.2	0.3	0.2	-0.3	-1.2	1.6	1.0	0.0	0.3	0.8	-0.1
Serious illness, injury or assault to yourself	0.3	0.4	2.8	1.1	0.2	0.1	0.8	0.0	0.5	-0.1	-0.3	-0.1	0.4	0.4	1.4	0.3	0.5	0.1	-0.5	1.7	0.4	0.5	0.4	0.6	0.3
Alcohol usually taken with meals	0.3	0.4	1.8	-0.2	0.4	0.7	0.5	0.6	-0.9	0.8	0.8	0.4	0.5	0.5	-0.9	0.3	0.3	0.9	1.3	-0.8	-0.7	0.4	0.4	-0.6	0.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	2.9	1.2	0.2	-0.2	0.1	-0.1	1.7	-0.4	-0.0	-0.0	0.2	-0.3	0.3	0.0	0.4	-0.4	0.5	1.0	-0.1	-0.4	0.3	-0.9	0.2
Mouth/teeth dental problems	0.3	0.5	5.0	-1.2	-0.2	0.0	-0.8	-0.2	-2.2	0.3	0.0	0.1	-0.2	0.1	-0.7	-0.3	-0.5	0.4	-0.8	-0.8	-1.2	0.3	0.4	-0.3	-0.2
Heart attack	0.3	0.4	1.4	-0.0	-1.2	-0.5	-0.4	-0.9	-0.8	-0.1	-0.1	-0.3	-0.4	-1.0	-0.3	-1.0	-1.0	-0.1	-0.2	-0.6	-0.8	-0.4	-0.8	0.8	-0.4
Allergy	0.3	0.7	2.4	1.6	-0.9	-1.0	-0.7	-1.1	0.3	-1.0	-0.7	-1.2	-0.7	-1.3	-0.4	-1.0	-0.8	-1.2	-0.1	-0.2	-0.6	-1.3	0.4	-0.2	-0.8
Diabetes (self-reported)	0.3	0.4	2.4	-1.0	0.9	0.5	0.2	0.2	1.0	0.1	-0.6	-0.4	0.3	0.5	0.3	0.9	0.7	0.2	-0.9	-0.2	-0.3	-0.1	-1.6	-0.9	0.3
Neuroticism score	0.3	0.5	1.4	-0.2	-0.7	-0.9	-0.7	-0.8	-0.9	-0.9	-0.7	-0.9	-0.7	-1.1	-0.5	-0.9	-0.6	-1.2	0.0	0.2	-0.1	-1.1	-0.3	-0.3	-0.9
Number of live births	0.3	0.4	1.6	-0.1	0.3	0.7	0.3	0.6	0.1	1.0	0.3	0.9	0.9	0.9	1.2	0.6	0.5	0.7	0.0	0.6	0.7	0.0	0.0	-0.6	0.9
Lung cancer (father)	0.3	0.3	2.1	0.6	-0.1	-0.2	-0.2	-0.5	0.4	-0.4	-1.1	-1.0	0.0	-0.2	-0.5	-0.3	0.1	-0.3	0.4	-0.5	-1.4	-0.5	0.3	-1.2	0.0
Medication: Paracetamol	0.3	0.4	3.3	-0.8	0.6	0.7	0.4	0.7	1.8	0.4	-0.4	0.2	0.5	0.9	0.7	0.6	0.7	0.3	0.4	-0.0	0.5	0.2	1.0	0.4	0.5
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.8	-0.2	-0.6	-0.8	-0.7	-0.7	-0.7	-0.9	-0.9	-0.8	-0.8	-0.6	-0.4	-0.7	-0.6	-0.9	-0.8	-0.5	0.1	-0.5	-0.2	0.4	-0.9
Medication: Seretide 50 evohaler	0.3	0.4	1.6	-0.3	1.1	0.5	1.0	0.6	1.3	0.1	0.2	0.0	0.4	0.9	0.3	0.8	0.9	0.1	0.5	0.5	-0.0	0.9	-0.6	-0.6	0.4
Heart disease (mother)	0.3	0.3	1.7	0.8	-0.2	-0.4	0.1	-0.9	1.0	-0.6	0.1	-0.4	-0.2	-1.3	0.5	-0.4	-0.1	-0.7	0.5	0.9	0.1	-0.3	-0.4	-0.3	-0.3
Had major operations	0.3	0.3	2.2	0.0	0.3	-0.2	-0.3	-0.4	0.7	-0.4	-0.9	-1.0	-0.2	-0.3	-0.1	0.1	0.1	-0.4	-0.6	-0.5	-0.5	-0.7	-1.5	-0.8	-0.3
Family relationship satisfaction	0.3	0.4	2.6	1.0	0.1	-0.1	0.0	-0.3	1.6	-0.3	-0.4	-0.5	0.3	-0.7	0.1	-0.0	0.4	-0.3	0.9	1.0	0.2	-0.2	1.2	1.0	0.3
Illnesses of father: Heart disease	0.3	0.4	2.6	-1.6	-0.4	0.2	0.3	0.0	-1.1	0.4	0.4	0.3	-0.4	0.0	0.8	-0.1	-0.7	0.7	-0.5	0.5	-0.2	1.2	-1.1	0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	2.3	1.2	0.5	0.4	1.3	0.0	0.8	0.4	0.9	0.7	0.7	0.1	1.1	0.5	0.6	0.4	-0.3	1.5	0.7	1.1	1.2	1.0	0.4
Handedness (chirality/laterality): Left-handed	0.3	0.3	2.8	1.7	0.0	0.1	0.6	0.2	0.3	0.3	-0.1	0.2	0.5	0.3	0.8	0.1	0.2	0.6	0.2	1.3	0.7	0.4	0.4	-0.3	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	2.2	-0.6	-0.2	-0.2	-0.6	0.0	-0.8	-0.5	-0.4	-0.4	-0.5	-0.1	-0.1	-0.2	-0.2	-0.5	0.1	-0.6	-0.4	-0.6	-1.5	-1.2	-0.2
Mother’s age at death	0.3	0.4	4.3	0.1	-0.2	0.0	-0.0	0.2	-0.7	0.2	0.4	0.1	0.0	0.3	-0.9	-0.3	-0.2	0.1	0.8	-1.0	-0.6	-0.3	-0.7	-2.1	0.1
Myopia	0.3	0.5	3.3	-1.2	0.7	0.6	-0.4	0.6	-1.8	0.5	0.4	-0.0	0.1	0.1	-0.9	0.6	0.1	0.3	0.6	-1.2	-0.6	-0.0	0.5	0.6	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.8	-0.7	0.5	0.7	0.6	0.9	0.2	0.7	0.8	0.6	0.4	0.7	-0.2	0.7	0.4	0.6	0.1	-0.7	0.6	0.6	-0.5	-0.2	0.5
Basal cell carcinoma (self-reported)	0.3	0.3	2.8	-0.6	-0.3	0.2	-0.4	-0.1	-0.0	0.3	0.5	0.3	0.0	0.5	-0.6	-0.2	-0.4	-0.1	-1.7	-0.8	-0.9	-0.3	-0.2	-0.9	-0.3
Depression (Nagel 2018)	0.2	0.2	2.2	0.2	0.2	0.0	0.4	-0.4	0.0	-0.3	-0.1	-0.3	0.3	-0.4	1.4	0.1	0.4	-0.3	0.5	1.5	0.1	-0.1	0.2	-0.1	0.3
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.5	-1.2	0.6	1.1	0.5	0.7	-0.7	1.1	0.4	0.7	0.8	0.9	0.7	0.6	0.4	1.2	-0.0	0.1	-0.2	0.7	-0.0	-0.2	0.9
Irritable Bowel Disease (IBD)	0.2	0.5	3.9	0.8	0.2	0.4	-0.2	0.3	-2.0	0.4	-0.1	0.4	0.8	0.3	0.8	0.2	0.6	0.0	1.0	0.4	0.6	-0.5	1.4	0.4	0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.4	2.6	-1.6	-0.6	0.0	-0.2	-0.4	-1.6	0.3	-0.0	0.0	-0.3	-0.2	0.9	-0.6	-0.7	0.4	-0.2	0.6	-0.3	0.6	0.2	1.3	-0.1
Breast Cancer	0.2	0.6	1.9	0.0	-0.8	-1.1	-0.4	-0.5	-0.7	-1.0	-0.8	-0.5	-0.9	-0.4	0.8	-0.7	-0.7	-0.9	-1.0	1.4	-0.1	-0.3	-0.1	1.0	-1.0
HDL Cholesterol	0.2	0.3	1.4	1.2	-0.8	-0.4	-0.4	-0.8	0.2	-0.2	-0.1	-0.3	-0.1	-0.5	-0.5	-0.9	-0.6	-0.3	-0.5	-0.5	-0.7	-0.4	0.7	-0.2	-0.1
Neuroticism (2016)	0.2	0.2	1.0	0.4	0.5	-0.4	0.4	0.1	-0.9	-0.8	-0.0	-0.5	-0.1	-0.2	-0.6	0.3	0.5	-0.7	0.2	-0.3	0.1	0.2	-0.6	-1.0	-0.2
Lung FVC	0.2	1.2	8.3	-1.6	-1.0	-0.5	-1.2	-0.3	-2.9	-0.4	-0.2	-0.3	-1.1	-0.8	-1.6	-0.8	-1.3	-0.3	-0.2	-2.2	-0.6	-0.3	-0.4	-0.8	-0.8
Neuroticism	0.2	0.5	1.4	-0.0	-0.9	-0.9	-0.7	-0.7	-0.7	-0.8	-0.6	-0.8	-0.5	-1.0	-0.6	-0.9	-0.6	-1.2	0.2	0.3	-0.1	-1.2	-0.6	-0.7	-0.8
Hand grip strength (left)	0.2	0.5	2.8	0.4	-0.5	-0.4	-0.4	-0.7	-1.6	-0.2	0.5	0.3	-0.5	-0.7	-1.1	-0.4	-0.6	-0.0	-0.8	-1.1	-0.5	-0.3	0.3	-1.7	-0.6
Relative age voice broke	0.2	0.3	2.2	1.0	-0.2	-0.4	0.4	-0.8	-0.7	-0.3	0.2	0.3	-0.1	-0.3	-0.2	-0.1	-0.1	-0.5	-1.5	1.1	0.1	0.2	0.0	0.5	-0.2
Age when periods started (menarche)	0.2	0.5	4.1	2.0	0.1	0.2	1.1	0.5	0.3	0.4	0.1	-0.2	0.9	0.9	0.6	0.0	0.6	0.4	0.8	1.3	0.8	0.6	0.3	-0.2	0.9
Medication: Atenolol	0.2	0.2	1.5	1.2	-0.3	0.1	0.7	-0.2	0.6	0.4	0.6	0.5	0.3	0.0	0.5	0.0	-0.0	0.5	-0.7	-0.0	0.3	0.6	-0.6	0.4	0.2
Hearing difficulty/problems with background noise	0.2	0.3	1.3	-0.8	0.5	0.4	0.1	0.6	-0.1	0.3	-0.2	0.0	0.4	0.4	1.1	0.3	0.5	0.1	1.1	0.5	0.6	0.0	-0.5	-0.4	0.4
Had menopause	0.2	0.2	1.1	-0.7	-0.4	-0.2	-0.5	-0.1	-0.5	-0.2	-0.5	-0.4	-0.2	-0.2	-0.3	-0.4	-0.3	-0.2	0.3	-0.8	-0.2	-0.5	-1.0	-0.6	-0.2
Medication: Ramipril	0.2	0.3	2.1	-0.5	0.4	-0.1	-0.3	0.3	0.5	-0.3	-0.5	-0.2	-0.2	0.2	-0.8	0.5	0.2	-0.2	-0.6	-0.6	-0.3	-0.2	-1.5	-0.9	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	3.2	-1.0	-0.8	-0.5	-1.2	-0.5	-1.8	-0.4	-0.2	-0.2	-0.8	-0.8	-0.9	-0.6	-1.0	-0.4	-0.2	-0.9	-0.7	-0.5	-0.5	-1.0	-0.6
Birth weight of first child	0.2	0.3	2.3	0.3	0.4	-0.0	0.3	0.6	1.5	-0.3	0.2	0.3	-0.1	0.5	-0.6	0.4	0.4	-0.1	1.1	-1.0	0.1	0.1	-0.0	-1.3	0.2
Pulse wave reflection index	0.2	0.2	1.0	-0.3	0.3	0.5	-0.0	0.5	-0.7	0.6	0.3	0.2	0.6	0.5	0.1	0.4	0.5	0.3	0.6	-0.1	0.4	-0.4	0.1	-1.0	0.5
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	2.3	-1.0	0.1	0.4	0.2	0.2	1.5	0.3	0.1	-0.1	-0.1	0.1	0.9	0.3	-0.1	0.4	-0.2	-0.0	0.2	0.2	-0.7	1.1	-0.1
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.2	0.1	0.2	0.0	0.7	0.1	1.1	0.1	-0.1	-0.1	0.5	0.4	0.1	0.1	0.6	-0.0	0.1	0.6	0.3	-0.1	-0.8	-0.7	0.2
Exposure to tobacco smoke outside home	0.2	0.3	2.3	-1.2	0.3	-0.1	0.0	0.1	-0.0	-0.1	0.0	-0.4	-0.1	-0.1	-0.8	0.1	0.1	-0.2	-0.1	-0.9	-0.4	-0.2	-1.5	-0.8	-0.3
Number of children fathered	0.2	0.2	0.6	0.5	-0.5	-0.5	-0.5	-0.6	-0.5	-0.4	-0.4	-0.8	-0.4	-0.4	-0.7	-0.7	-0.5	-0.3	-0.5	-0.1	-0.6	0.1	0.7	-0.1	-0.5
Age at first live birth	0.2	0.3	1.2	0.3	-0.6	-0.1	-0.8	-0.3	-0.6	-0.1	-0.3	-0.7	-0.4	-0.4	-0.9	-0.7	-0.7	-0.2	0.4	-1.1	-0.6	-0.6	0.5	0.3	-0.4
Qualifications: College or University degree	0.2	0.5	4.0	-2.0	-0.3	0.1	-1.3	0.3	-0.4	0.3	-0.4	-0.1	-0.5	0.2	-0.2	-0.2	-0.7	0.3	-0.2	-1.3	-0.5	-0.2	0.5	1.4	-0.2
Angina (self-reported)	0.2	0.2	1.8	-0.6	-0.1	-0.1	-0.1	0.0	0.1	-0.1	-0.0	-0.2	-0.2	0.0	1.0	-0.1	-0.2	-0.0	-0.2	1.4	0.7	0.4	0.2	0.9	-0.3
Number of full sisters	0.2	0.2	1.9	0.6	0.2	0.0	0.9	0.1	-0.2	-0.1	0.4	0.2	0.3	-0.1	-0.7	0.2	0.4	0.2	1.4	-0.5	-0.2	0.4	-0.3	-0.6	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.8	0.1	-0.5	-0.6	-0.6	-0.9	0.3	-0.5	-0.6	-0.8	-0.5	-0.8	0.2	-0.5	-0.5	-0.4	-0.2	0.6	0.0	-0.4	0.6	0.7	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.8	-0.3	-0.1	-0.2	0.0	-0.5	-0.6	-0.3	-0.0	-0.3	-0.3	-0.4	-0.8	-0.1	-0.2	-0.5	-0.7	-0.7	-0.6	-0.5	-0.9	-0.8	-0.5
Illnesses of siblings: Diabetes	0.2	0.3	2.3	0.2	-0.0	-0.2	0.2	-0.6	1.5	-0.5	-0.6	-0.5	-0.1	-0.3	-0.2	-0.0	0.1	-0.2	-0.2	1.1	-0.3	0.2	0.7	0.3	-0.2
Qualifications: nursing, teaching	0.2	0.3	1.0	-0.6	0.5	0.8	-0.1	0.9	-0.1	0.8	0.2	0.5	0.5	1.0	0.6	0.6	0.4	0.9	0.1	0.2	-0.1	0.5	0.8	-0.3	0.6
Commuting to job workplace: Walk	0.2	0.2	1.1	-0.1	-0.3	-0.2	-0.3	-0.4	0.9	-0.3	0.1	-0.4	-0.3	-0.5	-0.5	-0.4	-0.3	-0.7	0.0	-1.0	0.2	-0.5	-0.5	0.3	-0.2
Breast cancer (self-reported)	0.2	0.3	1.7	-0.8	-0.1	0.1	-0.6	0.4	-1.3	-0.1	-0.3	-0.0	-0.0	0.5	0.0	-0.0	0.1	-0.4	0.0	-0.7	-0.4	-0.6	-0.7	-1.3	0.0
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.3	0.0	0.5	0.5	0.7	0.2	1.1	0.5	0.8	0.5	0.6	0.3	0.4	0.2	0.5	0.4	0.2	0.6	-0.3	0.6	-0.5	-0.2	0.4
Supplements: Fish oil (including cod liver oil)	0.2	0.2	2.1	-0.5	-0.5	-0.4	-0.2	-0.2	-0.4	-0.1	-0.0	0.3	-0.4	-0.2	0.9	-0.4	-0.5	0.1	-0.0	0.7	0.2	0.2	0.1	1.4	-0.2
Alcohol drinker status: Never	0.2	0.3	1.7	-0.7	0.4	0.6	0.3	0.6	-1.3	0.6	0.4	-0.0	0.3	0.2	-0.2	0.4	0.2	0.6	1.0	-0.8	-0.2	0.5	0.7	-0.4	0.3
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.0	-0.0	0.3	0.6	0.1	0.6	-0.6	0.7	0.5	0.1	0.5	0.5	-0.7	0.1	0.2	0.6	0.1	-1.0	0.6	0.3	0.6	-0.5	0.4
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	0.3	-0.9	-0.4	-0.2	-0.7	-0.7	0.1	0.1	-0.1	-0.2	-0.9	0.1	-0.7	-0.8	0.1	-0.2	-0.1	-0.6	-0.2	-0.8	0.8	-0.2
Heart disease (siblings)	0.2	0.2	0.7	0.7	0.4	0.4	0.8	-0.1	-0.2	0.1	0.0	-0.1	0.6	0.2	0.3	0.4	0.7	0.3	0.3	0.8	-0.2	0.5	-0.3	-0.7	0.6
Fasting Glucose	0.1	0.1	0.8	-0.6	0.0	0.2	0.3	0.1	-0.9	-0.1	-0.0	0.5	-0.2	0.4	0.4	0.2	0.1	0.2	-0.1	-0.3	-0.2	0.6	0.3	0.1	0.4
Allergy or Eczema	0.1	0.2	0.6	-0.6	0.2	0.4	0.2	0.2	-0.8	0.4	0.3	0.3	0.4	0.3	-0.1	0.1	0.2	0.5	0.3	0.3	0.1	0.7	0.6	0.5	0.3
Tanning	0.1	1.7	3.2	1.2	1.1	1.4	1.7	1.1	-0.2	1.6	1.4	1.8	1.7	1.5	0.8	1.4	1.4	1.7	0.2	0.7	0.0	1.8	1.1	1.4	1.6
Angina	0.1	0.2	1.5	-0.3	-0.2	-0.2	-0.2	-0.2	0.3	-0.3	-0.2	-0.4	-0.3	-0.2	0.7	-0.2	-0.2	-0.1	-0.2	1.2	0.5	0.3	0.2	0.8	-0.3
Hand grip strength (right)	0.1	0.3	1.7	1.1	-0.2	-0.1	0.2	-0.3	-1.3	0.1	0.6	0.7	-0.0	-0.2	-0.1	0.0	-0.1	0.5	-0.9	0.1	0.5	0.7	1.1	0.6	-0.0
Hayfever, allergic rhinitis or eczema	0.1	0.2	2.8	-1.7	0.0	0.2	-0.1	0.3	-0.7	0.3	0.2	0.5	-0.0	0.3	-0.4	0.1	-0.1	0.4	-0.3	0.2	0.5	0.6	-0.3	0.3	0.0
Forced vital capacity (FVC)	0.1	0.5	1.7	0.8	0.0	0.4	0.4	0.3	-1.0	0.6	1.1	1.0	0.3	-0.1	-0.2	0.2	-0.1	0.8	0.9	0.1	0.7	1.1	1.3	0.6	0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	3.1	-0.9	-0.7	-0.5	-1.1	-0.5	-1.8	-0.4	-0.1	-0.1	-0.9	-0.9	-0.8	-0.5	-1.0	-0.3	-0.3	-0.6	-0.3	-0.2	-0.1	-0.1	-0.7
Tense / ‘highly strung’	0.1	0.2	1.9	-0.4	0.4	0.5	-0.0	0.5	-0.3	0.3	0.3	0.1	0.1	0.2	-0.3	0.3	0.2	0.0	0.8	-0.7	0.1	-0.2	-0.1	-1.4	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.3	-0.1	-0.1	0.2	-0.5	0.0	-0.4	0.3	0.7	0.4	-0.3	0.3	-0.1	-0.1	-0.5	-0.0	-1.1	0.1	-0.1	0.2	0.7	0.1	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.3	1.7	0.4	-0.1	0.3	0.2	0.4	-1.3	0.6	1.0	1.0	0.2	-0.1	-0.2	0.1	-0.1	0.7	0.9	-0.3	0.4	0.8	0.6	-0.4	0.5
Medication: Omeprazole	0.1	0.2	0.9	-0.9	0.1	0.4	0.5	0.5	0.1	0.3	0.4	0.2	0.0	0.4	-0.5	0.4	-0.0	0.3	-0.3	-0.6	0.4	0.4	-0.8	0.2	0.1
Smoking status: Previous	0.1	0.2	1.7	-0.1	0.4	0.2	0.0	0.6	-0.3	-0.1	0.1	-0.1	0.1	0.3	-0.4	0.2	0.4	-0.1	1.3	-0.4	-0.1	-0.0	0.8	-0.7	0.4
Back pain experienced in last month	0.1	0.1	0.5	-0.1	0.3	0.3	0.5	0.4	-0.2	0.3	0.3	0.1	0.2	0.6	0.1	0.2	0.2	0.4	-0.1	0.4	0.3	0.7	0.6	0.5	0.2
Mineral and other dietary supplements	0.1	0.1	0.4	0.4	-0.1	-0.3	-0.2	-0.6	0.0	-0.5	-0.3	-0.6	-0.3	-0.6	-0.2	-0.2	-0.3	-0.5	-0.6	0.5	-0.1	-0.3	0.2	0.1	-0.5
Average weekly champagne plus white wine intake	0.1	0.2	0.7	0.4	-0.1	0.2	0.7	0.3	-0.8	0.4	0.4	0.4	0.3	0.8	-0.1	-0.1	-0.1	0.8	-0.4	-0.1	-0.4	0.8	0.4	-0.5	0.3
Medication: Paracetamol	0.1	0.2	1.6	0.5	0.1	-0.0	0.2	0.0	0.8	-0.3	-0.9	-0.4	0.2	0.4	0.1	0.0	0.4	-0.4	-0.0	0.0	0.1	-0.3	1.3	-0.0	0.1
Commuting to job workplace: Cycle	0.1	0.2	0.6	-0.7	-0.6	-0.2	-0.3	-0.1	0.1	-0.0	-0.4	-0.3	-0.4	-0.1	0.7	-0.5	-0.7	0.1	-0.2	-0.4	0.8	-0.1	-0.2	0.5	-0.4
Blood Platelet Count	0.0	0.5	2.4	1.5	0.1	0.1	0.3	0.4	0.7	-0.3	0.1	-0.0	-0.0	0.1	-0.0	0.0	0.3	-0.2	1.1	0.3	1.3	0.3	1.6	1.4	0.3
Blood Red Count	0.0	0.3	1.2	-0.4	0.7	0.3	-0.4	0.6	0.5	-0.0	-0.1	-0.3	0.1	0.3	-1.0	0.4	0.5	-0.2	1.0	-1.1	-0.8	-0.3	-0.2	0.0	0.1
Hair Pigment	0.0	1.1	3.2	1.4	1.3	0.7	1.4	0.6	-1.3	0.3	-0.1	-0.0	0.9	0.8	1.0	1.3	1.2	0.8	-0.2	1.5	1.8	1.2	1.5	0.4	0.9

Hub : Genes

REEP5

Models

Trait associations