[Hub]/) : Traits : Leg fat percentage (left) : →

chr1:903,104-3,172,702

Best TWAS P=3.09e-12 · Best GWAS P=1.86e-08 conditioned to 0.0688

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP1-283E3.4	0.65	0.14	lasso	9	0.33	5.1e-28	-3.5	-6.1	1.0e-09	0.00	0.31	0.23	FALSE
2	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-3.5	-5.2	2.2e-07	-0.02	0.06	0.06	FALSE
3	GTEx	Artery Aorta	RP1-283E3.4	0.60	0.12	lasso	9	0.27	3.2e-15	-3.5	-5.8	6.3e-09	-0.01	0.19	0.18	FALSE
4	GTEx	Artery Tibial	RP1-283E3.4	0.66	0.09	lasso	6	0.38	4.9e-31	-3.5	-5.9	4.2e-09	0.01	0.33	0.20	FALSE
5	GTEx	Artery Tibial	RP11-345P4.10	0.61	0.10	lasso	10	0.36	3.1e-29	-3.4	5.5	4.1e-08	0.01	0.32	0.20	FALSE
6	GTEx	Cells Transformed fibroblasts	RP1-283E3.4	0.59	0.13	lasso	8	0.29	3.0e-22	3.1	-6.1	8.8e-10	0.01	0.38	0.07	FALSE
7	GTEx	Cells Transformed fibroblasts	RP11-345P4.10	0.66	0.17	lasso	13	0.32	7.5e-25	-3.4	5.4	7.0e-08	0.00	0.32	0.20	FALSE
8	GTEx	Esophagus Mucosa	RP1-283E3.4	0.53	0.12	enet	20	0.22	4.1e-15	-3.5	-6.6	5.0e-11	0.02	0.31	0.23	FALSE
9	GTEx	Esophagus Muscularis	RP1-283E3.4	0.46	0.14	enet	23	0.24	1.6e-14	-3.5	-7.0	3.1e-12	0.01	0.30	0.22	TRUE
10	GTEx	Esophagus Muscularis	RP3-395M20.12	0.08	0.06	enet	6	0.06	2.3e-04	3.8	-5.6	1.6e-08	0.78	0.01	0.97	TRUE
11	GTEx	Lung	RP1-283E3.4	0.58	0.07	lasso	7	0.34	8.8e-27	-3.5	-5.8	5.3e-09	0.02	0.34	0.16	FALSE
12	GTEx	Muscle Skeletal	SLC35E2B	0.35	0.06	lasso	4	0.19	3.2e-18	-3.4	6.1	8.3e-10	0.01	0.33	0.17	FALSE
13	GTEx	Muscle Skeletal	RP1-283E3.4	0.51	0.12	lasso	6	0.29	2.4e-28	-3.5	-5.9	3.3e-09	0.01	0.31	0.23	FALSE
14	GTEx	Muscle Skeletal	RP11-345P4.10	0.54	0.06	lasso	7	0.29	4.7e-29	-3.4	5.9	3.5e-09	0.00	0.35	0.15	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RP1-283E3.4	0.48	0.12	lasso	5	0.31	1.1e-17	-3.5	-6.2	4.8e-10	0.01	0.18	0.14	FALSE
16	GTEx	Thyroid	RP1-283E3.4	0.59	0.04	lasso	10	0.22	3.8e-17	-3.5	-6.6	3.8e-11	0.00	0.25	0.18	FALSE