Best TWAS P=1.17e-10 · Best GWAS P=6.02e-10 conditioned to 0.348
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | RP11-523H24.3 | 0.05 | 0.01 | lasso | 3 | 0.01 | 0.0816 | 5.0 | -5.7 | 1.3e-08 | -0.83 | 0.04 | 0.91 | FALSE |
2 | GTEx | Thyroid | PSPC1 | 0.11 | 0.04 | lasso | 4 | 0.02 | 0.0074 | 6.1 | -6.4 | 1.2e-10 | -0.90 | 0.01 | 0.98 | TRUE |