Best TWAS P=2.8e-08 · Best GWAS P=6.7e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | DLEU1 | 0.11 | 0.12 | lasso | 4 | 0.10 | 7.1e-09 | -4.8 | 5.3 | 1.5e-07 | -0.60 | 0.03 | 0.96 | FALSE |
2 | YFS | Blood | DLEU1 | 0.13 | 0.12 | lasso | 10 | 0.16 | 7.4e-49 | -4.8 | 5.4 | 6.0e-08 | -0.78 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | DLEU1 | 0.13 | 0.04 | lasso | 3 | 0.04 | 2.6e-03 | -5.4 | 5.6 | 2.8e-08 | -0.99 | 0.00 | 0.98 | TRUE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | TRIM13 | 0.04 | 0.00 | blup | 26 | 0.02 | 8.5e-03 | -2.0 | 5.3 | 9.2e-08 | -0.74 | 0.00 | 0.03 | FALSE |