Best TWAS P=4.48e-11 · Best GWAS P=7.65e-12 conditioned to 0.00605
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FARP1 | 0.10 | 0.05 | enet | 5 | 0.05 | 1.4e-06 | -6.3 | 6.3 | 4.1e-10 | -0.77 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | STK24 | 0.18 | 0.06 | lasso | 8 | 0.08 | 2.4e-07 | -5.0 | -5.7 | 1.3e-08 | 0.62 | 0.12 | 0.88 | FALSE |
| 3 | GTEx | Artery Tibial | STK24 | 0.12 | 0.10 | lasso | 3 | 0.08 | 8.4e-07 | -6.6 | -6.5 | 1.1e-10 | 0.94 | 0.01 | 0.99 | FALSE |
| 4 | GTEx | Esophagus Mucosa | FARP1-AS1 | 0.11 | 0.03 | lasso | 2 | 0.04 | 1.7e-03 | -6.3 | -6.4 | 2.0e-10 | 0.80 | 0.06 | 0.93 | FALSE |
| 5 | GTEx | Whole Blood | FARP1-AS1 | 0.19 | 0.07 | enet | 34 | 0.07 | 3.3e-07 | -6.3 | -5.5 | 3.2e-08 | 0.63 | 0.04 | 0.96 | FALSE |
| 6 | NTR | Blood | FARP1 | 0.02 | 0.01 | lasso | 3 | 0.01 | 4.3e-04 | -6.4 | -6.6 | 4.5e-11 | 0.78 | 0.04 | 0.95 | TRUE |