Best TWAS P=1.84e-11 · Best GWAS P=1.14e-14 conditioned to 8.96e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADAMTSL3 | 0.10 | 0.04 | lasso | 4 | 0.04 | 8.7e-06 | -6.6 | -6.1 | 8.3e-10 | 0.60 | 0.16 | 0.35 | TRUE |
| 2 | GTEx | Brain Cortex | GOLGA6L4 | 0.42 | 0.21 | lasso | 7 | 0.28 | 2.8e-08 | -5.0 | -5.5 | 3.7e-08 | 0.61 | 0.23 | 0.66 | FALSE |
| 3 | GTEx | Esophagus Muscularis | UBE2Q2P1 | 0.34 | 0.03 | lasso | 7 | 0.15 | 1.9e-09 | 3.8 | 6.7 | 1.8e-11 | -0.35 | 0.16 | 0.67 | TRUE |