Best TWAS P=1.14e-08 · Best GWAS P=9.75e-09 conditioned to 0.0556
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | PDIA2 | 0.12 | 0.01 | enet | 13 | 0.06 | 4.4e-05 | -5.5 | 5.4 | 6.7e-08 | -0.70 | 0.01 | 0.99 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PDIA2 | 0.15 | 0.07 | lasso | 8 | 0.10 | 5.2e-13 | -5.7 | -5.7 | 1.1e-08 | 0.81 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | AXIN1 | 0.03 | 0.01 | blup | 88 | 0.01 | 7.7e-03 | -4.7 | 5.5 | 3.4e-08 | -0.66 | 0.02 | 0.61 | FALSE |