Best TWAS P=7.69e-09 · Best GWAS P=1.13e-07 conditioned to 0.935
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2 | GTEx | Breast Mammary Tissue (Male) | GLG1 | 0.20 | -0.01 | lasso | 5 | 0.02 | 8.9e-02 | -5.3 | 5.8 | 7.7e-09 | -0.91 | 0.01 | 0.71 | TRUE |
| 4 | GTEx | Esophagus Mucosa | RFWD3 | 0.20 | 0.18 | lasso | 5 | 0.23 | 3.5e-15 | 4.2 | 5.3 | 8.6e-08 | -0.82 | 0.08 | 0.89 | FALSE |
| 1 | GTEx | Adipose Visceral Omentum | RFWD3 | 0.14 | 0.03 | enet | 15 | 0.04 | 3.0e-03 | 3.6 | 5.3 | 1.3e-07 | -0.73 | 0.10 | 0.80 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | RFWD3 | 0.20 | 0.14 | lasso | 5 | 0.15 | 9.2e-09 | -5.0 | 5.2 | 1.5e-07 | -0.83 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | RFWD3 | 0.35 | 0.25 | enet | 31 | 0.27 | 2.5e-09 | -5.0 | 5.2 | 2.3e-07 | -0.74 | 0.03 | 0.96 | FALSE |
| 6 | GTEx | Stomach | RFWD3 | 0.20 | 0.08 | enet | 20 | 0.13 | 1.2e-06 | 3.9 | 5.2 | 2.3e-07 | -0.71 | 0.05 | 0.93 | FALSE |