Best TWAS P=8.38e-08 · Best GWAS P=3.24e-09 conditioned to 0.0029
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LCT | 0.02 | 0.02 | enet | 3 | 0.03 | 7.6e-07 | -5.3 | 5.4 | 8.4e-08 | -0.72 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LCT | 0.04 | 0.02 | blup | 36 | 0.02 | 1.9e-03 | -4.4 | 5.3 | 9.4e-08 | -0.71 | 0.01 | 0.96 | FALSE |
| 3 | YFS | Blood | MCM6 | 0.18 | 0.15 | enet | 20 | 0.20 | 8.5e-64 | -5.3 | -5.3 | 1.1e-07 | 0.64 | 0.06 | 0.94 | FALSE |
| 2 | NTR | Blood | CCNT2 | 0.01 | 0.00 | blup | 370 | 0.00 | 6.7e-02 | -4.4 | -5.3 | 1.4e-07 | 0.43 | 0.05 | 0.78 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DARS | 0.04 | 0.02 | blup | 40 | 0.01 | 2.1e-02 | -4.6 | -5.3 | 1.4e-07 | 0.75 | 0.01 | 0.89 | FALSE |
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100129961 | 0.17 | 0.14 | enet | 9 | 0.14 | 2.6e-17 | 4.9 | 5.2 | 1.5e-07 | -0.47 | 0.04 | 0.96 | FALSE |