Best TWAS P=1.54e-10 · Best GWAS P=8.7e-15 conditioned to 0.00626
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | GRB14 | 0.14 | 0.09 | lasso | 7 | 0.06 | 0.00016 | 6.2 | -6.4 | 1.5e-10 | -0.46 | 0.29 | 0.42 | TRUE |
2 | GTEx | Thyroid | COBLL1 | 0.07 | 0.05 | lasso | 3 | 0.05 | 0.00015 | -5.0 | 5.1 | 3.0e-07 | 0.59 | 0.57 | 0.24 | TRUE |