Best TWAS P=1.65e-07 · Best GWAS P=2.78e-07 conditioned to 0.747
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pituitary | SEC22A | 0.34 | 0.03 | enet | 47 | 0.08 | 0.00401 | 1.4 | -5.2 | 1.7e-07 | 0.46 | 0.04 | 0.50 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ADCY5 | 0.03 | 0.00 | blup | 76 | 0.01 | 0.00046 | 2.2 | -5.1 | 3.0e-07 | 0.72 | 0.02 | 0.08 | TRUE |