TWAS
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Traits
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Traits
:
Leg fat percentage (left)
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chr3:122,223,182-123,672,874
Best TWAS P=1.65e-07 · Best GWAS P=2.78e-07 conditioned to 0.747
122.2M
122.4M
122.6M
122.8M
123M
123.2M
123.4M
123.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Pituitary
SEC22A
0.34
0.03
enet
47
0.08
0.00401
1.4
-5.2
1.7e-07
0.46
0.04
0.50
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
ADCY5
0.03
0.00
blup
76
0.01
0.00046
2.2
-5.1
3.0e-07
0.72
0.02
0.08
TRUE