[Hub]/) : Traits : Leg fat percentage (left) :

chr3:134,986,214-137,261,517

Best TWAS P=3.72e-11 · Best GWAS P=4.82e-10 conditioned to 0.0248

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPP2R3A 0.05 0.02 lasso 4 0.05 7.7e-07 5.1 5.5 3.5e-08 -0.32 0.57 0.15 FALSE
2 GTEx Artery Coronary SLC35G2 0.16 0.03 lasso 8 0.05 6.4e-03 4.6 -5.5 3.1e-08 0.51 0.15 0.37 FALSE
3 GTEx Brain Cerebellar Hemisphere RP11-731C17.2 0.16 0.02 enet 24 0.09 3.0e-03 -4.4 5.5 4.9e-08 -0.85 0.07 0.69 FALSE
4 GTEx Cells Transformed fibroblasts RP11-85F14.5 0.10 0.08 enet 38 0.09 3.9e-07 -4.3 5.5 4.7e-08 -0.54 0.94 0.05 FALSE
5 GTEx Lung RP11-85F14.5 0.07 0.05 lasso 19 0.05 8.8e-05 -5.0 5.4 7.4e-08 -0.67 0.84 0.12 FALSE
6 GTEx Muscle Skeletal RP11-731C17.2 0.15 0.12 lasso 16 0.12 3.8e-12 -4.3 5.2 2.2e-07 -0.50 0.99 0.01 FALSE
7 GTEx Testis RP11-85F14.5 0.12 0.03 enet 28 0.02 3.8e-02 -4.3 5.7 1.5e-08 -0.55 0.50 0.15 FALSE
8 GTEx Thyroid RP11-85F14.5 0.07 0.00 lasso 7 0.01 4.7e-02 -5.0 6.6 3.7e-11 -0.70 0.07 0.54 TRUE