TWAS hub - ADCY5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1698	0.0519	1.1e-05	0.029	NA	0.026	NA	0.035	0.0022	NA	0.0039	NA	0.00089
2	TCGA	Breast Invasive Carcinoma	0.0334	0.0186	4.1e-03	0.005	0.014	0.014	NA	0.006	0.0310	0.00046	0.0006	NA	0.02100

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Birth weight of first child	14.7	26.6	50.1	7.1	1.8
Birth weight	13.7	29.7	57.8	7.6	-1.3
Medication: Lansoprazole	5.1	5.8	6.4	-2.3	-2.5
Leg fat percentage (right)	5.0	18.2	28.3	-2.9	-5.3
Diabetes (mother)	4.9	6.3	11.8	-3.4	0.9
Leg fat percentage (left)	4.8	17.3	26.2	-2.9	-5.1
Body fat percentage	4.7	18.6	25.5	-3.4	-5.0
Leg fat mass (right)	4.6	17.9	21.9	-3.7	-4.7
Trunk fat percentage	4.5	18.1	21.3	-3.9	-4.6
Trunk fat mass	4.5	19.4	20.0	-4.5	-4.3
Leg fat mass (left)	4.4	17.4	20.1	-3.8	-4.5
Whole body fat mass	4.1	17.0	17.4	-4.1	-4.2
Ever had hysterectomy (womb removed)	3.8	4.3	5.8	-2.4	-1.7
Arm fat percentage (left)	3.7	14.7	21.7	-2.8	-4.7
Type 2 Diabetes (T2D) (2018)	3.6	6.8	9.8	-3.1	1.9
Alzheimer’s Disease (including proxy)	3.4	4.9	9.6	-3.1	-0.4
Waist circumference	3.3	11.9	14.2	-3.8	-3.1
Arm fat mass (left)	3.3	13.6	14.2	-3.6	-3.8
Pulse wave reflection index	3.2	3.9	5.5	-1.5	-2.3
Emphysema/chronic bronchitis	3.2	3.6	4.8	-2.2	-1.5
Arm fat percentage (right)	3.1	12.3	19.0	-2.4	-4.4
Arm fat mass (right)	3.1	13.0	14.4	-3.4	-3.8
Nervous feelings	3.0	5.6	8.4	2.9	1.7
Hip circumference	3.0	12.9	18.4	-4.3	-2.7
Diabetes (father)	2.9	3.6	4.7	-2.2	1.6
Weight	2.8	13.8	17.8	-4.2	-3.1
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.7	9.2	-3.0	1.5
Major Depression (MDD)	2.7	3.3	5.6	-2.4	1.0
Diabetes (self-reported)	2.7	4.2	5.9	-1.6	2.4
Friendships satisfaction	2.6	3.2	6.2	2.5	-0.5
Commuting to job workplace: Walk	2.5	2.7	5.1	0.6	2.2
Wears glasses or contact lenses	2.4	2.8	5.5	2.4	-0.1
BMI	2.3	13.2	14.2	-3.5	-3.8
Diabetes diagnosed by doctor	2.3	3.8	4.7	-2.2	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.3	4.8	6.5	1.8	2.5
Alcohol drinker status: Never	2.3	2.8	3.3	-1.8	-1.5
Chronotype (morning person)	2.2	5.0	9.8	-3.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.3	2.9	1.7	1.3
Triglycerides	2.1	3.5	5.9	-2.4	-1.0
Blood Eosinophil Count	2.1	15.9	22.3	4.7	3.1
Sitting height	2.1	15.2	29.8	-5.5	0.8
Hair/balding pattern: Pattern 3	2.1	3.1	4.0	-2.0	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.6	13.1	0.3	3.6
Alzheimer’s Disease (in father)	2.0	2.1	4.3	-2.1	-0.1
Standing height	2.0	20.0	39.7	-6.3	0.5
Mouth/teeth dental problems: Loose teeth	2.0	2.4	2.6	-1.5	-1.6
Angina (self-reported)	2.0	2.6	3.0	-1.5	-1.7
Pack years adult smoking proportion	1.9	2.8	3.3	-1.6	-1.8
Wheeze or whistling in the chest in last year	1.9	3.4	6.6	-0.6	-2.6
Number of full sisters	1.9	2.3	4.0	0.8	2.0
Eye problems/disorders: Glaucoma	1.9	2.3	4.1	2.0	0.7
Pack years of smoking	1.9	2.8	3.3	-1.5	-1.8
Irritable Bowel Disease (IBD)	1.8	4.3	5.7	-2.4	-1.7
Ulcerative Colitis (UC)	1.8	3.4	4.6	-2.2	-1.5
Blood White Count	1.8	13.1	13.9	3.5	-3.7
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	4.0	2.0	-0.9
Body mass index (BMI)	1.8	7.7	12.5	-1.7	-3.5
Financial difficulties in last 2 years	1.8	2.4	4.2	-0.8	-2.1
Angina	1.7	2.2	2.5	-1.4	-1.6
Townsend deprivation index at recruitment	1.7	2.4	3.9	2.0	-0.9
Stomach or abdominal pain in last month	1.7	2.1	4.2	-0.4	-2.0
Number of children fathered	1.7	1.9	3.5	-1.9	-0.6
Medication: Seretide 50 evohaler	1.7	2.0	3.9	-2.0	-0.2
Illness, injury, bereavement, stress in last 2 years	1.7	2.0	4.1	0.1	2.0
Basal cell carcinoma (self-reported)	1.7	2.0	3.7	-0.6	-1.9
Reaction Time	1.6	3.0	3.2	-1.7	-1.8
Prostate Cancer	1.6	2.2	3.7	-0.9	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	2.4	1.4	-1.6
Ever highly irritable/argumentative for 2 days	1.6	2.0	3.8	1.9	-0.4
Arm fat-free mass (right)	1.6	8.3	15.9	-4.0	-0.8
Comparative body size at age 10	1.6	4.4	4.7	-2.0	-2.2
Arm predicted mass (right)	1.6	8.3	15.7	-4.0	-0.9
Loneliness, isolation	1.6	2.2	4.2	2.1	0.4
Allergy or Eczema	1.5	4.0	4.2	2.0	2.0
Pulse rate	1.5	2.5	3.8	1.1	2.0
Forced vital capacity (FVC), Best measure	1.5	5.4	10.8	0.0	3.3
Commuting to job workplace: Car/motor vehicle	1.5	1.7	2.2	-1.5	-1.1
Eye problems/disorders: Cataract	1.5	1.7	3.3	-0.2	-1.8
High cholesterol (Self-reported)	1.5	2.6	2.8	-1.7	-1.5
Heart attack/myocardial infarction (self-reported)	1.5	2.0	2.3	1.3	-1.5
Bipolar Disorder (2018)	1.4	2.3	4.5	-0.1	-2.1
Body Mass Index (BMI) (2010)	1.4	1.9	3.6	-0.5	-1.9
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.2	-1.8	0.1
Average weekly fortified wine intake	1.4	1.6	3.2	-0.2	-1.8
Hair/balding pattern: Pattern 2	1.4	1.7	2.8	0.8	1.7
Mean time to correctly identify matches	1.4	2.6	3.2	-1.4	-1.8
Pulse rate, automated reading	1.4	4.5	6.6	2.6	-1.6
Family relationship satisfaction	1.4	1.7	3.2	1.8	0.5
Medication: Omeprazole (e.g. Zanprol)	1.4	1.6	3.3	-1.8	0.1
Arm predicted mass (left)	1.4	7.0	13.0	-3.6	-1.0
Crohns Disease (2017)	1.3	2.8	3.1	-1.6	-1.8
Blood Red Count	1.3	12.3	17.4	-2.7	-4.2
Medication: Metformin	1.3	1.9	2.5	-1.6	1.1
Hayfever, allergic rhinitis or eczema	1.3	2.9	2.9	1.7	1.7
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	8.6	-0.4	2.9
Medication: Cholesterol lowering	1.3	1.9	2.1	-1.5	-1.3
Comparative height size at age 10	1.3	7.0	8.9	-3.0	2.2
Leg pain on walking	1.3	1.6	2.8	-0.6	1.7
Ever had bowel cancer screening	1.3	1.5	2.8	-1.7	-0.4
Basal metabolic rate	1.3	7.4	13.5	-3.7	-1.1
Arm fat-free mass (left)	1.3	6.8	13.0	-3.6	-0.8
Height	1.2	22.9	45.7	-6.8	-0.4
Average weekly spirits intake	1.2	1.5	1.6	1.3	-1.2
Heart attack	1.2	1.6	1.8	1.2	-1.3
Medication: Simvastatin	1.2	1.8	2.3	-1.1	-1.5
Noisy workplace	1.2	1.5	2.9	-1.7	0.1
Prospective memory result	1.2	1.5	2.3	1.5	0.8
Length of working week for main job	1.2	1.3	1.8	1.3	-0.9
Medication: Ibuprofen	1.2	1.5	2.7	1.6	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.4	-1.5	-0.7
Depression (Nagel 2018)	1.1	1.7	3.2	0.4	-1.8
Lupus	1.1	1.7	3.0	-1.7	0.6
Blood Platelet Count	1.1	12.3	20.3	4.5	-2.1
Leg fat-free mass (left)	1.1	5.7	9.5	-3.1	-1.4
Leg predicted mass (left)	1.1	5.6	9.4	-3.1	-1.4
Trunk fat-free mass	1.1	6.1	12.1	-3.5	-0.1
Alcohol intake versus 10 years previously	1.1	1.7	3.2	1.8	0.4
Trunk predicted mass	1.1	6.0	12.0	-3.5	-0.1
High blood pressure (siblings)	1.1	1.6	2.1	-1.1	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	1.6	-1.3	-1.0
Average weekly beer plus cider intake	1.1	1.6	2.0	-1.4	-1.0
Diastolic blood pressure, automated reading	1.1	3.3	6.5	0.3	-2.6
Pain experienced in last month	1.1	1.8	2.9	0.9	1.7
HDL Cholesterol	1.0	1.6	2.8	1.7	0.7
Hypothyroidism (self reported)	1.0	2.2	2.6	-1.4	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	4.1	-2.0	-0.7
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.6	1.2	-0.8
Serious illness, injury or assault to yourself	1.0	1.2	1.4	1.0	1.2
Neuroticism score	1.0	2.1	2.2	1.5	1.4
Mouth/teeth dental problems: Dentures	1.0	1.7	2.8	-1.7	-0.8
Pulse wave Arterial Stiffness index	1.0	1.2	1.6	-0.9	-1.2
Loud music exposure frequency	1.0	1.1	1.3	1.1	1.0
Chest pain or discomfort	1.0	1.5	2.5	0.7	1.6
Whole body fat-free mass	1.0	5.8	11.4	-3.4	-0.5
Handedness (chirality/laterality): Left-handed	1.0	1.2	1.6	-1.3	-0.8
Whole body water mass	1.0	5.6	10.6	-3.3	-0.7
Guilty feelings	1.0	1.6	2.3	0.9	1.5
Illnesses of father: High blood pressure	1.0	1.3	2.2	-0.5	-1.5
Risk taking	1.0	1.4	2.0	-1.4	-0.9
Ever depressed for a whole week	1.0	1.3	2.4	0.4	-1.5
Cholesterol lowering medication	1.0	1.4	1.7	-1.3	-1.1
Bipolar Disorder (2011)	0.9	0.8	1.6	0.3	-1.2
Fasting Glucose	0.9	1.1	1.2	-1.1	1.0
Relative age of first facial hair	0.9	1.8	3.5	1.9	0.1
Qualifications: CSEs or equivalent	0.9	1.1	1.4	1.2	0.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	1.6	1.3	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	2.9	1.7	0.2
Hearing difficulty/problems with background noise	0.9	1.4	2.4	1.6	-0.6
Forced vital capacity (FVC)	0.9	3.5	6.6	-0.7	2.6
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.2	-2.1	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	1.2	1.0	-1.1
Lung cancer (father)	0.9	1.1	2.0	0.4	1.4
Alcohol intake frequency.	0.9	2.2	3.4	1.8	-1.0
Medication for cholesterol	0.9	1.4	2.4	0.6	1.5
Medication: Gliclazide	0.9	1.0	1.4	-0.8	1.2
Miserableness	0.9	1.6	1.6	1.2	1.3
Intelligence (Savage-Jansen 2018)	0.8	2.3	3.7	1.0	-1.9
Heel T-Score	0.8	6.7	12.3	-3.5	1.0
Lung FVC	0.8	3.9	4.3	1.9	2.1
Number of treatments/medications taken	0.8	1.5	2.8	-0.3	-1.7
Systolic blood pressure, automated reading	0.8	2.2	3.4	-1.0	-1.8
Hand grip strength (right)	0.8	2.3	2.4	-1.5	1.6
Fed-up feelings	0.8	1.5	2.8	1.7	-0.5
High blood pressure	0.8	2.3	4.2	2.0	-0.7
Qualifications: None of the above	0.8	1.6	2.9	0.6	-1.7
Illnesses of siblings	0.8	1.1	1.2	1.0	1.1
Time employed in main current job	0.8	0.9	1.1	1.0	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	1.8	1.4	-0.9
Gout (self-reported)	0.8	1.1	2.0	-1.4	-0.4
Eye problems/disorders: None of the above	0.8	1.0	1.9	-0.1	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	1.0	-0.9	1.0
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	1.8	-1.4	-0.7
Leg predicted mass (right)	0.8	4.0	7.4	-2.7	-0.8
Mother’s age at death	0.8	1.0	1.9	-1.4	0.2
Financial situation satisfaction	0.8	0.9	1.7	1.3	-0.4
Age started oral contraceptive pill	0.8	1.0	1.6	-1.3	-0.7
Vascular/heart problems diagnosed by doctor	0.8	2.1	3.1	-1.8	1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	1.1	1.0	1.0
HbA1C	0.7	0.8	1.6	-1.3	-0.3
Hearing difficulty/problems: Yes	0.7	1.0	1.5	1.2	-0.7
Severe depression (siblings)	0.7	0.8	0.8	-0.9	0.9
Allergy	0.7	1.7	3.0	-1.7	-0.6
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.2	1.1	-0.7
Leg fat-free mass (right)	0.7	3.8	7.0	-2.6	-0.7
Average weekly red wine intake	0.7	1.1	2.1	-0.0	-1.4
Qualifications: nursing, teaching	0.7	1.1	1.9	-0.5	1.4
Ever taken oral contraceptive pill	0.7	0.8	0.8	0.9	0.8
Alzheimer’s Disease (in mother)	0.6	0.7	1.4	-1.2	-0.1
Breast Cancer	0.6	1.3	2.7	-0.0	1.6
Respiratory disease	0.6	1.3	2.5	1.6	-0.3
Hand grip strength (left)	0.6	1.5	2.8	-1.7	0.3
Taking other prescription medications	0.6	0.9	1.8	-1.3	-0.0
Age when periods started (menarche)	0.6	1.5	2.9	1.7	0.2
Mouth/teeth dental problems	0.6	0.9	1.5	0.5	1.2
Father’s age at death	0.6	0.7	1.2	-0.5	-1.1
Peak expiratory flow (PEF)	0.6	1.5	2.3	-0.8	1.5
Blood clot in the leg (DVT)	0.6	0.7	0.8	0.9	0.8
Pulse wave peak to peak time	0.6	0.7	1.4	0.3	1.2
Knee pain experienced in last month	0.6	1.0	1.4	-1.2	-0.7
Hypertension (Self-reported)	0.6	1.8	3.2	1.8	-0.6
Breast cancer (self-reported)	0.6	0.7	0.7	-0.9	0.8
Asthma (self-reported)	0.6	1.1	1.7	1.3	-0.7
Hearing aid user	0.6	0.7	1.0	1.0	0.6
Medication: Bendroflumethiazide	0.6	0.9	1.8	-0.3	-1.3
Medication: Paracetamol	0.6	0.9	1.5	-1.2	-0.5
Unable to work because of sickness or disability	0.6	0.8	1.2	-1.1	0.5
Coronary Artery Disease (CAD)	0.5	0.6	1.2	-1.1	0.3
Cardiovascular Disease	0.5	1.6	2.5	1.6	-0.9
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	0.9	0.6	0.9
Fluid intelligence score	0.5	1.1	1.6	0.8	-1.2
Falls in the last year	0.5	0.6	0.7	0.7	0.8
Medication: Paracetamol	0.5	0.8	1.6	-1.3	-0.1
Headache pain in last month	0.5	0.8	1.6	0.0	-1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.6	0.1	1.2
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	1.6	-0.7	-1.3
Shortness of breath walking on level ground	0.5	0.6	0.7	0.8	-0.8
Migraine (self-reported)	0.5	0.6	0.7	0.9	-0.8
Overall health rating	0.5	1.0	1.6	0.6	-1.3
Age at last live birth	0.5	0.8	1.3	0.4	-1.2
Medication: Aspirin	0.5	0.6	0.8	0.6	0.9
Long-standing illness, disability or infirmity	0.5	0.7	1.3	1.2	0.3
Illnesses of father: None of the above (group 1)	0.5	0.6	0.8	0.9	0.7
Smoking status: Current	0.5	0.7	0.9	-1.0	-0.7
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.2	0.3	1.1
Medication: Lisinopril	0.5	0.6	1.1	-0.4	1.0
Rheumatoid Arthritis	0.4	0.5	1.0	0.1	1.0
Current tobacco smoking	0.4	0.6	0.7	-0.8	-0.7
Chronic bronchitis/emphysema (father)	0.4	0.5	0.6	0.8	-0.6
High blood pressure (mother)	0.4	0.5	0.7	0.9	-0.6
Asthma	0.4	0.9	1.3	1.1	-0.7
Exposure to tobacco smoke at home	0.4	0.5	0.9	-1.0	-0.1
Exposure to tobacco smoke outside home	0.4	0.6	1.1	0.3	-1.0
Worry too long after embarrassment	0.4	0.7	1.3	-0.1	1.1
Age at first live birth	0.4	0.8	1.3	1.1	-0.6
Neck or shoulder pain in last month	0.4	0.6	1.1	0.1	-1.1
Had major operations	0.4	0.5	0.5	0.6	-0.7
Mood swings	0.4	0.7	0.8	0.8	-0.9
Osteoporosis (self-reported)	0.4	0.5	0.9	1.0	-0.4
Medication: Aspirin	0.4	0.5	0.7	0.6	0.8
Average weekly champagne plus white wine intake	0.4	0.6	0.7	0.7	0.9
Medication: Blood pressure	0.4	0.9	1.0	1.0	-0.8
Depressed Affect (Nagel 2018)	0.3	0.6	1.0	1.0	0.5
Neuroticism (2016)	0.3	0.4	0.7	0.2	0.9
Sensitivity / hurt feelings	0.3	0.6	0.9	-0.5	1.0
Impedance of leg (right)	0.3	1.5	3.1	-1.8	-0.0
Impedance of leg (left)	0.3	1.5	2.8	-1.7	0.4
Past tobacco smoking	0.3	0.5	0.9	0.2	0.9
Had menopause	0.3	0.3	0.6	-0.2	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.4	0.6	-0.6
Depression (self-reported)	0.3	0.4	0.4	-0.6	0.6
Illnesses of mother	0.3	0.4	0.7	0.9	0.0
Tense / ‘highly strung’	0.3	0.4	0.7	0.8	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.9	0.2	1.0
Qualifications: College or University degree	0.3	0.8	1.1	1.1	0.8
Medication: Blood pressure	0.3	0.6	1.0	1.0	-0.5
Medication: Allopurinol	0.3	0.4	0.6	-0.8	0.4
Medication: Omeprazole	0.3	0.3	0.6	-0.8	-0.1
Suffer from ‘nerves’	0.3	0.5	0.7	0.6	0.9
Illnesses of father: Heart disease	0.3	0.4	0.7	0.8	0.2
Illnesses of siblings: Diabetes	0.3	0.4	0.6	-0.8	0.4
Number of operations (self-reported)	0.3	0.4	0.4	-0.7	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.7	-0.8	-0.1
Commuting to job workplace: Cycle	0.3	0.4	0.7	0.3	0.8
Myopia	0.3	0.4	0.7	-0.3	-0.9
Bipolar Disorder or Schizophrenia	0.2	0.5	0.7	0.5	-0.8
Schizophrenia (2018)	0.2	0.4	0.5	0.7	0.5
Age at First Birth	0.2	0.4	0.6	-0.4	-0.8
Mean Putamen Volume	0.2	0.2	0.5	0.1	-0.7
Primary Biliary Cirrhosis	0.2	0.3	0.3	0.5	-0.5
Waist Hip Ratio (WHR)	0.2	0.8	1.6	-1.2	0.0
Lung FEV1/FVC ratio	0.2	1.3	2.4	0.3	1.6
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.5	-0.3	-0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	-0.7	0.0
Vitamin and mineral supplements	0.2	0.3	0.4	-0.5	-0.6
Supplements: Zinc	0.2	0.2	0.3	0.4	0.5
Relative age voice broke	0.2	0.3	0.6	-0.0	-0.8
Multivitamins +/- minerals	0.2	0.3	0.3	0.6	0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	0.7	0.2	0.8
Glaucoma (self-reported)	0.2	0.3	0.3	0.6	0.4
Medication: Amlodipine	0.2	0.3	0.4	0.7	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.4	0.2	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.3	-0.6	0.4
Medication for pain relief, constipation, heartburn	0.2	0.4	0.6	0.8	0.4
Smoking status: Previous	0.2	0.2	0.4	0.4	-0.6
Back pain experienced in last month	0.2	0.3	0.6	0.8	0.0
Commuting to job workplace: Public transport	0.2	0.2	0.3	-0.2	-0.6
Fractured/broken bones in last 5 years	0.2	0.2	0.4	0.6	-0.3
Alcohol drinker status: Previous	0.2	0.2	0.3	-0.4	-0.6
Impedance of whole body	0.2	0.9	1.8	-1.3	-0.2
Neuroticism (Nagel 2018)	0.1	0.2	0.4	0.2	0.6
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.7	0.1	-0.8
Crohns Disease (2012)	0.1	0.2	0.3	0.5	-0.4
LDL Cholesterol	0.1	0.1	0.2	-0.1	-0.4
Ulcerative Colitis	0.1	0.1	0.2	-0.4	0.1
Systolic Blood Pressure	0.1	0.3	0.3	0.5	0.6
Smoking Status	0.1	0.1	0.3	-0.1	-0.5
Hair Pigment	0.1	2.8	4.2	-2.0	1.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.3	0.6	-0.1
Medication for hormone replacement therapy	0.1	0.2	0.3	-0.2	-0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.2	-0.4	-0.2
Supplements: Glucosamine	0.1	0.2	0.3	0.2	-0.5
Medication: Atenolol	0.1	0.1	0.2	0.5	-0.0
Medication: Levothyroxine sodium	0.1	0.2	0.3	-0.5	-0.3
Alcohol usually taken with meals	0.1	0.1	0.3	0.2	-0.5
Had other major operations	0.1	0.2	0.2	0.4	0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.2	0.5	0.3
Pain all over the body in last month	0.1	0.1	0.2	-0.1	0.5
Medication: Ramipril	0.1	0.2	0.3	0.5	0.2
Worrier / anxious feelings	0.1	0.2	0.3	0.5	0.3
Number of live births	0.1	0.2	0.3	-0.4	0.5
Happiness	0.1	0.1	0.1	0.3	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.5	-0.7	-0.3
Impedance of arm (left)	0.1	0.5	1.0	-1.0	-0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	0.1	0.4
Number of full brothers	0.1	0.2	0.3	-0.2	0.5
Health satisfaction	0.1	0.1	0.1	0.2	-0.4
Heart disease (mother)	0.1	0.1	0.1	-0.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.4	-0.2
Supplements: Vitamin C	0.1	0.1	0.1	0.3	-0.4
Mineral and other dietary supplements	0.1	0.2	0.4	0.6	0.1
Osteoarthritis (self-reported)	0.1	0.1	0.1	0.2	-0.3
Number of self-reported non-cancer illnesses	0.1	0.1	0.2	0.4	0.0
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.3	-0.3
Medication: Atorvastatin	0.1	0.1	0.2	-0.4	-0.3
Irritability	0.1	0.1	0.2	0.4	-0.3
Supplements: Calcium	0.1	0.2	0.3	-0.6	-0.1
Schizophrenia vs Biploar Disorder	0.0	0.1	0.1	0.0	0.3
Worry (Nagel 2018)	0.0	0.0	0.0	0.1	-0.0
Ovarian Cancer	0.0	0.0	0.0	-0.2	0.2
Schizophrenia (2014)	0.0	0.1	0.1	0.1	0.3
Neuroticism	0.0	0.1	0.1	0.3	0.4
Tanning	0.0	0.2	0.3	0.5	0.4
Medication: Co-codamol	0.0	0.0	0.0	0.1	0.1
Maternal smoking around birth	0.0	0.1	0.1	0.3	0.2
Number of incorrect matches in round	0.0	0.0	0.1	0.3	0.1
Impedance of arm (right)	0.0	0.2	0.2	-0.3	0.5
Breastfed as a baby	0.0	0.0	0.0	0.2	0.1
Hair/balding pattern: Pattern 4	0.0	0.0	0.0	0.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.2	0.1
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.1	0.1
Ever smoked	0.0	0.1	0.2	0.0	-0.4
Heart disease (siblings)	0.0	0.1	0.1	-0.2	0.3

Hub : Genes

ADCY5

Models

Trait associations