Best TWAS P=6.35e-12 · Best GWAS P=1.75e-13 conditioned to 0.000363
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.03 | enet | 9 | 0.02 | 6.8e-04 | 5.9 | 6.9 | 6.4e-12 | 0.70 | 0.09 | 0.88 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | TEX15 | 0.05 | 0.04 | lasso | 4 | 0.04 | 2.7e-06 | 6.0 | 5.7 | 1.4e-08 | 0.66 | 0.46 | 0.54 | FALSE |