Best TWAS P=1.2e-08 · Best GWAS P=1.08e-08 conditioned to 0.178
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | RP11-122A3.2 | 0.14 | 0.04 | enet | 14 | 0.07 | 8.5e-06 | -2.8 | 5.3 | 1.1e-07 | 0.44 | 0.18 | 0.18 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LRRC69 | 0.04 | 0.04 | blup | 69 | 0.05 | 1.3e-09 | 4.7 | 5.5 | 4.8e-08 | 0.71 | 0.03 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LRRC69 | 0.02 | 0.01 | blup | 67 | 0.01 | 1.1e-02 | 5.3 | 5.3 | 1.4e-07 | 0.80 | 0.03 | 0.74 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LRRC69 | 0.11 | 0.12 | blup | 67 | 0.11 | 2.1e-11 | 5.3 | 5.3 | 1.1e-07 | 0.79 | 0.03 | 0.97 | FALSE |
5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LRRC69 | 0.09 | 0.08 | blup | 67 | 0.09 | 5.6e-07 | 5.3 | 5.5 | 3.4e-08 | 0.81 | 0.02 | 0.98 | FALSE |
6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | LRRC69 | 0.24 | 0.17 | enet | 14 | 0.18 | 7.0e-07 | 4.9 | 5.7 | 1.2e-08 | 0.90 | 0.02 | 0.97 | TRUE |
7 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | LRRC69 | 0.16 | 0.06 | blup | 69 | 0.06 | 7.2e-03 | 5.3 | 5.3 | 1.2e-07 | 0.71 | 0.02 | 0.59 | FALSE |