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chr9:14,857,740-16,758,776

Best TWAS P=1.62e-31 · Best GWAS P=1.53e-27 conditioned to 0.195

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-10.9	-11.7	1.6e-31	0.91	0.05	0.94	TRUE
12	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	9.0	8.7	4.3e-18	-0.85	0.16	0.51	TRUE
5	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-10.5	-11.0	3.3e-28	0.97	0.03	0.97	FALSE
11	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-10.5	-10.4	1.7e-25	0.96	0.11	0.89	FALSE
3	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	9.3	-10.4	1.9e-25	0.95	0.06	0.94	FALSE
13	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	9.3	-9.9	3.7e-23	0.90	0.21	0.73	FALSE
6	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-8.9	-9.8	1.2e-22	0.92	0.08	0.88	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	9.4	-9.5	1.6e-21	0.81	0.87	0.13	FALSE
7	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	9.6	-9.2	2.9e-20	0.83	0.07	0.87	FALSE
8	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-10.9	-9.2	4.7e-20	0.91	0.04	0.85	FALSE
16	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	9.6	-8.8	2.1e-18	0.79	0.19	0.60	FALSE
10	GTEx	Lung	CCDC171	0.13	0.03	enet	9	0.01	5.0e-02	6.5	-8.2	2.1e-16	0.72	0.42	0.33	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf93	0.06	0.05	lasso	3	0.03	5.3e-03	8.8	-7.4	1.3e-13	0.70	0.13	0.28	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CCDC171	0.14	0.09	enet	13	0.12	1.9e-10	9.0	-6.8	1.5e-11	0.63	0.99	0.01	FALSE
2	GTEx	Artery Tibial	CCDC171	0.10	0.09	enet	9	0.12	7.2e-10	5.6	-6.4	1.5e-10	0.60	0.90	0.09	FALSE
9	GTEx	Breast Mammary Tissue	CCDC171	0.21	0.01	lasso	5	0.03	1.5e-02	8.8	-5.6	1.8e-08	0.55	0.37	0.20	FALSE
1	GTEx	Artery Aorta	CCDC171	0.18	0.05	lasso	5	0.08	2.2e-05	-3.2	-5.2	2.0e-07	0.31	0.34	0.06	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CCDC171	0.20	0.04	enet	45	0.06	4.9e-04	9.5	-5.2	2.0e-07	0.40	0.67	0.22	FALSE