TWAS
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Traits
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Leg fat percentage (left)
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chr10:64,195,778-65,606,229
Best TWAS P=2.36e-08 · Best GWAS P=3.38e-09 conditioned to 8.23e-06
64.2M
64.4M
64.6M
64.8M
65M
65.2M
65.4M
65.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
NTR
Blood
NRBF2
0.03
0.01
bslmm
386
0.01
3.4e-05
-3.2
-5.6
2.4e-08
0.30
0.19
0.08
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NRBF2
0.10
0.06
lasso
7
0.08
3.5e-09
5.0
5.2
2.6e-07
-0.44
0.21
0.78
FALSE