[Hub]/) : Traits : Leg fat percentage (left) :

chr10:20,372,032-22,724,472

Best TWAS P=3.69e-21 · Best GWAS P=5.8e-22 conditioned to 0.11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NEBL 0.07 0.01 blup 662 0.03 9.7e-05 -5.1 -6.3 3.8e-10 -0.03 0.76 0.01 TRUE
2 GTEx Artery Tibial CASC10 0.05 0.06 lasso 4 0.02 1.3e-02 3.6 5.9 3.4e-09 0.52 0.25 0.49 FALSE
3 GTEx Skin Sun Exposed Lower leg MLLT10 0.06 0.02 lasso 4 0.03 8.0e-04 9.2 -9.4 3.7e-21 -0.94 0.01 0.99 TRUE
4 GTEx Skin Sun Exposed Lower leg CASC10 0.08 0.02 lasso 5 0.01 6.1e-02 7.7 8.7 3.6e-18 0.90 0.08 0.82 FALSE
5 GTEx Spleen MLLT10 0.16 0.02 lasso 7 0.02 1.0e-01 7.7 -8.7 4.6e-18 -0.92 0.02 0.62 FALSE