Hub : Genes

NRBF2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cortex	0.2960	0.0760	1.5e-05	0.257	NA	0.214	NA	0.188	9.8e-08	NA	1.4e-06	NA	6.8e-06
2	GTEx	Brain Frontal Cortex BA9	0.2495	0.0827	4.8e-04	0.173	NA	0.121	NA	0.157	2.4e-05	NA	4.4e-04	NA	6.1e-05
3	GTEx	Esophagus Mucosa	0.1450	0.0580	8.4e-05	0.111	NA	0.076	NA	0.112	7.4e-08	NA	8.3e-06	NA	6.4e-08
4	GTEx	Esophagus Muscularis	0.1050	0.0410	9.5e-04	0.030	NA	0.034	NA	0.021	5.9e-03	NA	3.8e-03	NA	1.9e-02
5	GTEx	Nerve Tibial	0.0848	0.0359	6.8e-04	0.085	NA	0.059	NA	0.050	1.2e-06	NA	5.0e-05	NA	1.9e-04
6	GTEx	Skin Sun Exposed Lower leg	0.0560	0.0260	5.1e-03	0.006	NA	-0.002	NA	-0.001	9.2e-02	NA	5.3e-01	NA	4.0e-01
7	GTEx	Stomach	0.0880	0.0410	8.4e-03	0.038	NA	0.007	NA	0.028	6.3e-03	NA	1.5e-01	NA	1.6e-02
8	GTEx	Testis	0.1440	0.0520	7.4e-04	0.084	NA	0.074	NA	0.093	1.5e-04	NA	3.5e-04	NA	6.7e-05
9	GTEx	Thyroid	0.1100	0.0410	3.6e-05	0.048	NA	0.065	NA	0.074	1.3e-04	NA	9.6e-06	NA	2.5e-06
10	NTR	Blood	0.0307	0.0133	1.5e-03	0.010	0.009	0.009	0.013	0.009	1.9e-04	5.2e-04	5.2e-04	3.5e-05	4.6e-04
11	ROSMAP	Brain Pre-frontal Cortex	0.3396	0.0438	0.0e+00	0.458	0.413	0.457	0.433	0.461	1.3e-65	2.3e-57	2.3e-65	4.9e-61	3.1e-66
12	YFS	Blood	0.3331	0.0472	0.0e+00	0.122	0.165	0.171	0.165	0.168	7.2e-38	1.6e-51	1.2e-53	2.0e-51	1.1e-52
13	TCGA	Bladder Urothelial Carcinoma	0.0750	0.0420	1.4e-03	0.038	0.020	0.020	NA	0.017	3.3e-04	7.4e-03	7.9e-03	NA	1.2e-02
14	TCGA	Breast Invasive Carcinoma	0.0544	0.0207	6.2e-10	0.065	0.051	0.052	NA	0.058	3.1e-13	1.3e-10	6.1e-11	NA	5.5e-12
15	TCGA	Colon Adenocarcinoma	0.1310	0.0560	1.4e-05	0.098	0.090	0.093	NA	-0.004	2.9e-06	6.7e-06	4.9e-06	NA	7.6e-01
16	TCGA	Glioblastoma Multiforme	0.1730	0.0730	1.1e-04	0.089	0.124	0.127	NA	0.103	1.2e-03	1.3e-04	1.1e-04	NA	4.9e-04
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0364	0.0189	3.1e-03	0.036	0.027	0.033	NA	0.030	6.6e-05	4.4e-04	1.3e-04	NA	2.4e-04
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0982	0.0372	9.2e-08	0.060	0.055	0.070	NA	0.079	2.3e-07	7.5e-07	2.3e-08	NA	3.6e-09
19	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0780	0.0410	6.6e-03	0.006	0.031	0.008	NA	0.013	1.4e-01	6.6e-03	1.1e-01	NA	5.4e-02
20	TCGA	Brain Lower Grade Glioma	0.0802	0.0298	3.0e-07	0.081	0.055	0.077	NA	0.043	1.7e-09	6.4e-07	4.3e-09	NA	1.1e-05
21	TCGA	Lung Adenocarcinoma	0.0859	0.0356	2.9e-06	0.064	0.060	0.067	NA	0.023	5.5e-08	1.6e-07	2.7e-08	NA	8.8e-04
22	TCGA	Lung Squamous Cell Carcinoma	0.0860	0.0399	3.2e-05	0.019	0.020	0.042	NA	0.035	2.6e-03	2.1e-03	1.4e-05	NA	6.3e-05
23	TCGA	Pancreatic Adenocarcinoma	0.1840	0.0700	8.1e-06	0.132	0.072	0.083	NA	0.058	3.6e-06	5.8e-04	2.5e-04	NA	1.9e-03
24	TCGA	Pheochromocytoma and Paraganglioma	0.0830	0.0500	8.7e-03	0.024	0.042	0.024	NA	0.036	3.7e-02	8.6e-03	3.9e-02	NA	1.4e-02
25	TCGA	Prostate Adenocarcinoma	0.0825	0.0316	4.9e-07	0.088	0.059	0.076	NA	0.080	1.9e-09	8.1e-07	2.2e-08	NA	9.7e-09
26	TCGA	Thyroid Carcinoma	0.1360	0.0480	1.0e-08	0.105	0.079	0.087	NA	0.044	2.3e-10	3.8e-08	8.1e-09	NA	3.6e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Blood Platelet Count	84.1	974.9	1325.0	-35.1	-34.5	-34.3	-30.1	-32.4	-24.1	-28.3	-36.2	-23.1	7.7	-35.1	-8.7	-30.5	-35.6	-27.2	-29.3	-35.1	-32.3	-28.2	-36.4	-33.9	-34.5	-34.3	-30.1	-35.7	-36.2
Blood White Count	24.8	183.5	259.2	15.4	15.7	16.1	8.6	15.2	7.4	12.7	15.5	12.5	-10.1	15.8	6.7	12.2	15.7	13.7	13.9	15.4	14.3	9.6	15.6	15.0	10.7	14.1	13.5	15.7	13.9
Triglycerides	19.7	32.2	47.6	6.2	6.6	6.9	4.3	6.5	4.9	4.2	6.4	6.4	-3.0	6.5	1.4	5.8	6.5	5.9	6.2	6.0	5.3	3.6	6.3	6.2	4.7	6.4	5.5	6.1	5.9
Supplements: Zinc	17.9	19.5	27.9	-5.2	-5.1	-4.3	-5.1	-4.7	-2.0	-3.8	-5.1	-3.2	1.3	-5.2	-2.3	-3.5	-5.2	-4.2	-4.2	-5.2	-5.0	-3.5	-5.3	-4.6	-4.0	-4.6	-4.8	-5.2	-4.6
Qualifications: None of the above	15.6	33.4	61.9	5.8	6.6	6.2	5.5	6.1	3.1	3.8	6.0	5.9	-3.4	6.7	-0.4	5.8	6.9	5.8	7.1	6.1	4.9	2.7	6.8	5.9	5.1	7.9	6.3	6.4	6.9
Average weekly beer plus cider intake	13.8	20.0	29.3	5.4	5.4	5.2	2.9	4.9	1.4	4.6	5.2	3.9	-2.7	5.4	1.2	3.9	5.2	3.9	4.5	5.2	4.9	3.3	5.1	4.9	3.9	4.5	4.4	5.3	5.1
Diastolic blood pressure, automated reading	11.2	34.6	90.6	7.0	6.8	6.8	4.6	5.8	9.5	6.0	6.7	3.6	-3.5	6.7	-0.7	3.5	6.2	4.3	4.0	6.8	7.0	4.4	6.4	5.4	6.7	6.0	5.3	6.6	6.1
Mineral and other dietary supplements	11.1	14.9	31.0	4.7	4.1	3.9	4.3	3.6	4.4	5.6	4.5	1.8	-2.5	4.1	0.4	2.3	3.8	1.6	1.7	4.5	5.0	4.9	4.5	3.7	5.2	3.8	2.0	4.3	3.3
Average weekly red wine intake	10.7	15.7	28.6	-4.3	-4.6	-4.0	-3.8	-4.5	-3.3	-3.6	-4.2	-5.1	1.9	-4.5	1.0	-2.7	-4.3	-3.3	-3.4	-4.3	-4.2	-3.7	-4.4	-4.4	-4.5	-5.3	-2.7	-4.4	-3.9
Alcohol usually taken with meals	10.4	16.8	25.2	-4.8	-4.8	-4.6	-3.4	-4.2	-2.7	-4.0	-4.8	-3.0	3.1	-5.0	-0.0	-3.1	-4.7	-3.1	-4.0	-4.9	-4.7	-3.2	-4.6	-4.2	-4.0	-4.3	-3.9	-4.9	-4.9
HDL Cholesterol	10.3	17.3	25.2	-4.2	-4.6	-4.5	-4.0	-4.5	-3.4	-3.0	-4.5	-4.6	1.8	-4.7	-1.4	-4.5	-4.9	-4.7	-4.8	-4.5	-3.7	-2.5	-4.7	-4.6	-3.4	-5.0	-4.4	-4.5	-4.2
Impedance of arm (right)	10.3	47.9	72.2	-7.7	-8.1	-8.0	-5.2	-7.8	-4.6	-5.7	-7.7	-6.7	4.8	-8.1	-2.7	-5.8	-8.2	-7.5	-7.9	-7.7	-6.7	-2.5	-7.8	-6.7	-4.9	-7.8	-8.5	-7.8	-7.6
Impedance of arm (left)	10.2	47.1	71.7	-7.5	-8.1	-8.1	-4.5	-7.8	-4.6	-5.7	-7.6	-7.0	4.7	-8.1	-2.8	-6.0	-8.2	-7.5	-8.2	-7.6	-6.5	-2.2	-7.6	-6.8	-4.4	-7.5	-8.5	-7.8	-7.6
Multivitamins +/- minerals	10.1	12.9	27.6	-4.5	-3.9	-3.4	-4.2	-3.2	-4.0	-5.2	-4.5	-0.0	2.2	-4.2	-0.6	-1.4	-3.8	-2.0	-1.5	-4.6	-5.2	-3.6	-4.1	-3.1	-4.2	-2.6	-3.1	-4.3	-3.3
Supplements: Glucosamine	9.9	12.9	26.9	-4.2	-3.7	-3.6	-4.4	-3.4	-5.2	-4.8	-4.2	-0.5	1.9	-3.8	-0.4	-2.3	-3.6	-1.9	-1.8	-4.2	-4.6	-4.2	-4.2	-3.4	-4.6	-3.1	-2.4	-4.0	-3.4
Qualifications: A levels/AS levels or equivalent	9.4	20.8	32.3	-4.7	-5.3	-5.0	-3.4	-5.7	-2.8	-3.8	-4.8	-5.6	1.8	-5.2	-0.3	-4.3	-5.4	-4.4	-5.4	-4.9	-4.1	-2.7	-5.2	-5.0	-3.7	-5.4	-4.7	-5.1	-5.3
Lung FEV1/FVC ratio	9.1	46.3	82.8	7.4	7.8	7.9	5.7	8.2	9.1	6.2	7.3	7.4	-2.8	7.5	0.9	6.2	7.4	6.1	7.1	7.0	6.2	4.3	7.4	7.0	5.9	7.8	6.3	7.3	7.2
Relative age of first facial hair	8.9	18.2	30.3	-5.3	-4.9	-4.7	-3.7	-4.6	-2.5	-5.4	-5.3	-2.2	4.5	-4.8	-2.0	-2.1	-4.6	-2.4	-2.6	-5.1	-5.5	-4.5	-4.8	-3.9	-4.9	-4.0	-3.6	-4.9	-4.1
Deep venous thrombosis (DVT) (self-reported)	8.1	10.4	17.3	-3.9	-3.5	-3.8	-1.8	-3.5	-2.5	-3.8	-4.2	-1.3	0.4	-3.7	-2.5	-2.6	-3.6	-2.5	-2.5	-4.0	-4.1	-3.0	-3.7	-3.5	-3.0	-2.3	-3.2	-4.0	-3.6
Relative age voice broke	8.0	12.2	21.9	-4.4	-4.2	-3.7	-3.0	-4.0	-1.6	-3.8	-4.3	-1.6	2.1	-4.2	-2.1	-2.1	-4.0	-2.4	-2.3	-4.4	-4.7	-3.6	-4.0	-3.6	-3.6	-3.0	-3.1	-4.3	-3.4
Age when periods started (menarche)	7.7	18.4	27.8	-4.7	-4.8	-5.3	-2.6	-4.6	-2.1	-4.8	-4.9	-3.0	3.7	-4.9	-2.0	-4.0	-5.0	-4.1	-4.2	-4.9	-4.7	-3.7	-4.9	-4.8	-3.9	-4.1	-3.9	-5.0	-4.7
Blood clot in the leg (DVT)	7.7	9.9	16.9	-3.8	-3.4	-3.7	-1.6	-3.3	-2.6	-3.5	-4.1	-1.3	0.3	-3.5	-2.4	-2.4	-3.5	-2.4	-2.4	-3.9	-4.1	-3.0	-3.5	-3.4	-3.0	-2.3	-3.1	-3.9	-3.6
High blood pressure (siblings)	7.6	10.9	36.4	3.6	3.7	4.0	1.2	3.4	6.0	2.8	3.4	3.9	-1.4	3.6	0.8	2.6	3.6	3.5	3.2	3.4	3.1	2.1	3.5	3.5	2.4	3.8	2.9	3.5	2.9
Supplements: Calcium	7.6	8.3	16.6	-3.5	-3.0	-3.0	-2.8	-2.8	-1.9	-3.7	-3.7	-1.0	0.3	-3.2	-1.6	-1.6	-3.1	-2.0	-1.1	-3.6	-4.1	-4.1	-3.4	-3.2	-3.7	-2.3	-2.0	-3.4	-2.4
High blood pressure	7.4	20.6	50.8	5.2	4.8	5.0	4.9	4.8	7.1	4.3	5.0	2.4	-1.3	4.9	1.5	3.5	4.7	2.7	2.8	5.2	5.2	5.1	5.0	4.6	5.7	4.5	3.2	5.1	4.4
Hypertension (Self-reported)	7.3	20.3	46.2	5.1	4.9	5.0	4.7	4.9	6.8	4.1	5.0	2.5	-1.3	4.9	1.8	3.8	4.8	3.0	3.2	5.1	5.0	4.6	5.0	4.6	5.4	4.5	3.6	5.1	4.5
Number of full sisters	7.2	8.8	21.3	3.4	3.4	3.8	2.0	2.8	4.6	3.0	3.3	2.7	-1.4	3.4	0.3	2.2	3.2	2.6	2.7	3.4	3.3	1.7	3.1	3.1	2.3	3.0	2.8	3.4	3.0
Intelligence (Savage-Jansen 2018)	7.0	21.7	44.7	-4.8	-5.3	-4.5	-5.2	-5.3	-0.6	-3.1	-5.3	-4.2	3.3	-5.2	0.4	-4.5	-5.3	-3.5	-5.5	-4.9	-4.0	-2.3	-5.3	-4.4	-4.9	-5.8	-5.3	-5.2	-6.7
Age at first live birth	7.0	12.4	21.1	-3.5	-4.0	-4.4	-2.3	-4.0	-3.2	-3.4	-3.6	-4.6	2.6	-3.9	-0.1	-3.4	-4.0	-3.8	-4.4	-3.5	-2.7	-1.3	-3.9	-3.6	-2.3	-4.6	-3.6	-3.7	-3.5
Depression (Nagel 2018)	6.4	9.7	32.1	3.0	3.6	3.3	2.2	3.6	1.2	2.0	3.0	5.7	-2.4	3.4	0.0	3.2	3.5	3.2	4.2	2.9	2.1	0.8	3.3	3.3	1.9	4.2	3.0	3.2	3.4
Vascular/heart problems diagnosed by doctor	6.4	17.4	47.5	-4.8	-4.5	-4.9	-3.8	-4.5	-6.9	-4.0	-4.6	-2.6	1.2	-4.5	-1.0	-3.2	-4.3	-2.8	-2.8	-4.7	-4.7	-4.1	-4.5	-4.2	-4.9	-4.2	-3.2	-4.7	-4.0
Qualifications: O levels/GCSEs or equivalent	6.3	10.0	17.1	-2.9	-3.5	-3.5	-1.9	-3.9	-2.1	-1.8	-3.2	-3.4	1.1	-3.5	-0.7	-3.8	-3.8	-3.4	-4.1	-3.2	-2.4	-1.6	-3.7	-3.4	-2.7	-4.1	-3.5	-3.4	-3.9
Gout (self-reported)	6.2	8.5	14.5	3.5	3.3	3.7	1.6	3.0	3.8	2.8	3.3	2.1	-0.5	3.3	1.3	2.5	3.2	2.8	2.3	3.4	3.3	3.0	3.4	3.3	2.8	2.7	2.3	3.3	2.5
Vitamin and mineral supplements	6.1	8.2	18.6	3.6	2.9	2.3	4.1	2.4	2.3	4.2	3.5	0.5	-0.2	3.2	1.4	1.1	3.0	1.7	0.8	3.7	4.3	4.0	3.4	2.8	3.7	2.3	1.9	3.4	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	6.1	8.1	23.5	3.0	3.5	2.9	2.6	3.1	1.2	1.6	2.8	4.8	-2.6	3.2	-0.5	2.6	3.2	2.6	3.8	2.8	2.2	0.8	3.0	2.9	1.7	3.7	2.7	3.0	3.3
Age at last live birth	5.9	8.6	15.3	-3.2	-3.3	-3.8	-2.1	-3.3	-2.1	-3.9	-3.4	-2.8	1.3	-3.3	-0.9	-2.7	-3.3	-2.8	-2.9	-3.2	-2.9	-2.1	-3.3	-3.1	-2.5	-3.6	-2.6	-3.2	-2.5
Medication: Blood pressure	5.9	11.3	24.9	4.0	3.7	3.7	3.1	3.8	5.0	4.2	3.8	2.3	-0.2	3.8	1.7	2.5	3.5	2.7	2.2	3.9	4.0	3.4	3.6	3.6	3.3	3.1	2.5	3.8	2.6
Supplements: Fish oil (including cod liver oil)	5.8	7.5	20.8	-3.4	-2.8	-2.6	-3.2	-2.5	-3.2	-4.6	-3.3	-1.2	1.9	-2.8	0.3	-1.2	-2.5	-0.5	-0.7	-3.1	-3.7	-3.9	-3.1	-2.5	-3.8	-2.5	-0.9	-3.0	-1.9
Impedance of whole body	5.7	28.9	41.9	-5.8	-6.3	-6.1	-4.3	-6.3	-3.8	-4.3	-5.9	-6.1	3.7	-6.3	-2.2	-4.8	-6.3	-5.9	-6.5	-5.8	-4.8	-1.7	-5.8	-5.2	-3.5	-6.3	-6.5	-6.0	-5.9
Pack years adult smoking proportion	5.6	8.6	19.4	2.5	3.3	3.1	1.6	3.3	1.7	1.6	2.7	4.3	-3.4	3.0	-1.1	3.2	3.3	3.0	4.4	2.5	1.5	-0.4	3.2	2.5	1.8	4.2	3.6	2.8	3.9
Body mass index (BMI)	5.6	24.0	35.9	5.5	5.8	5.1	5.1	4.9	4.1	5.1	5.6	4.4	-5.2	5.7	-0.6	2.8	5.5	3.5	4.2	5.6	5.5	3.4	5.6	4.5	5.2	6.0	4.3	5.6	5.1
Exposure to tobacco smoke outside home	5.6	7.5	23.3	2.9	3.2	3.0	2.0	3.6	1.7	3.3	2.8	4.8	-1.4	3.0	-0.1	2.2	3.0	2.7	3.1	2.6	2.2	1.5	2.8	3.0	1.7	3.4	2.0	2.8	2.4
Age at First Birth	5.5	8.0	12.3	-3.1	-3.3	-3.1	-2.3	-3.2	-0.9	-1.7	-2.9	-3.1	1.4	-3.2	-1.0	-3.3	-3.4	-3.0	-3.3	-3.1	-2.6	-2.2	-3.4	-3.4	-2.3	-3.5	-2.6	-3.2	-2.7
Body Mass Index (BMI) (2010)	5.3	7.3	11.5	2.9	3.1	3.1	3.1	3.2	0.2	2.8	3.2	2.5	-2.2	3.0	-0.5	2.1	3.0	2.3	2.6	2.9	2.7	2.3	3.2	2.8	2.8	3.4	2.1	2.9	2.7
Medication: Ventolin 100micrograms inhaler	5.3	6.8	13.0	-2.8	-2.8	-2.5	-3.6	-2.7	-3.2	-2.8	-2.8	-2.3	0.1	-2.8	-0.9	-2.8	-2.9	-2.4	-2.7	-2.6	-2.2	-1.8	-2.9	-2.8	-2.3	-2.9	-2.4	-2.7	-2.7
BMI	5.1	29.7	42.8	6.4	6.5	6.1	4.8	5.7	4.5	5.8	6.4	4.7	-5.2	6.4	-0.4	3.2	6.1	4.0	4.6	6.4	6.4	3.8	6.1	5.2	5.4	6.0	5.0	6.4	5.8
Bilateral oophorectomy (both ovaries removed)	5.0	5.8	8.5	2.5	2.5	2.9	1.7	2.9	2.0	2.4	2.6	2.6	-0.8	2.6	0.9	2.9	2.7	2.0	2.5	2.4	2.0	2.1	2.8	2.6	2.7	2.9	2.1	2.5	2.6
Allergy	4.9	11.3	16.4	3.8	3.7	4.0	2.9	3.3	3.2	3.7	3.9	2.0	-0.7	3.8	2.4	3.6	3.8	3.2	3.5	3.7	3.4	2.0	3.7	3.5	2.5	2.9	3.9	3.9	4.0
Qualifications: College or University degree	4.9	15.3	30.7	-3.8	-4.6	-3.4	-5.0	-4.5	0.0	-3.1	-3.9	-5.2	3.4	-4.4	1.8	-2.8	-4.4	-3.1	-4.9	-3.9	-3.0	-1.0	-4.3	-3.4	-3.4	-5.5	-4.2	-4.1	-5.0
Blood Red Count	4.8	46.3	68.7	7.7	8.0	6.8	7.4	8.3	0.5	5.6	7.6	7.3	-2.6	7.9	3.8	6.6	7.8	7.4	6.8	7.5	6.8	5.4	7.7	8.2	5.5	7.2	6.1	7.6	6.3
Current tobacco smoking	4.7	7.6	15.6	2.5	3.0	2.9	1.6	3.1	0.2	2.3	2.5	3.8	-3.6	2.9	0.5	2.9	3.2	3.3	4.0	2.5	1.7	0.4	3.2	2.7	1.5	3.5	3.4	2.8	3.0
Fluid intelligence score	4.7	9.8	23.2	-2.7	-3.3	-2.6	-3.9	-3.4	0.5	-1.9	-3.1	-3.2	3.7	-3.2	1.9	-2.9	-3.5	-2.0	-3.9	-2.9	-2.1	-1.2	-3.6	-2.7	-3.8	-4.5	-3.3	-3.1	-4.8
Leg fat percentage (right)	4.7	17.1	28.9	4.8	4.9	4.3	4.1	3.5	3.6	4.6	4.7	3.3	-5.4	4.8	-1.5	1.8	4.4	2.1	2.7	4.8	5.1	3.7	4.8	3.7	5.1	4.9	2.9	4.7	4.0
Overall health rating	4.7	10.0	16.9	3.3	3.6	3.4	2.9	3.6	3.3	2.0	3.2	3.8	-1.6	3.4	1.1	3.2	3.5	3.5	3.6	3.2	2.7	1.7	3.5	3.5	2.6	4.1	3.2	3.5	3.3
Leg fat percentage (left)	4.7	17.0	31.1	4.8	4.9	4.3	4.0	3.5	3.7	4.4	4.6	3.2	-5.6	4.8	-1.6	1.6	4.4	2.2	2.7	4.8	5.2	3.5	4.8	3.6	5.0	4.9	3.0	4.7	4.0
Pack years of smoking	4.7	6.9	16.2	2.1	2.9	2.7	1.4	2.7	1.6	1.1	2.4	3.6	-3.2	2.7	-1.1	2.8	3.0	2.8	4.0	2.3	1.4	-0.7	2.8	2.2	1.6	3.9	3.4	2.6	3.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.5	5.4	7.3	-2.7	-2.4	-2.6	-2.7	-2.3	-2.2	-2.5	-2.7	-1.7	-0.1	-2.6	-1.7	-2.4	-2.6	-2.3	-2.3	-2.5	-2.2	-1.6	-2.6	-2.3	-1.8	-2.3	-2.5	-2.5	-2.3
Verbal and Numeric Reasoning (VNR)	4.4	10.5	25.6	-3.0	-3.7	-2.7	-3.9	-3.7	0.4	-1.6	-3.3	-3.2	2.6	-3.5	1.4	-3.2	-3.7	-2.4	-4.4	-3.1	-2.2	-0.5	-3.7	-2.6	-3.3	-4.6	-4.1	-3.4	-5.1
Exposure to tobacco smoke at home	4.3	4.8	9.8	2.2	2.5	2.4	2.3	2.9	2.0	1.5	2.3	3.1	-0.1	2.3	0.6	2.5	2.4	2.0	2.5	2.0	1.5	2.1	2.2	2.6	2.0	2.5	1.5	2.1	2.5
Medication: Seretide 50 evohaler	4.3	4.9	10.5	-2.1	-2.3	-2.3	-3.2	-2.5	-2.5	-1.2	-2.3	-2.6	0.0	-2.3	-0.5	-2.0	-2.4	-1.4	-2.2	-2.3	-2.1	-1.5	-2.5	-2.1	-2.5	-3.0	-1.9	-2.4	-2.7
Smoking status: Current	4.3	6.9	16.0	2.2	2.7	2.8	1.3	3.0	0.4	1.9	2.3	3.9	-3.3	2.6	0.7	3.0	3.1	3.2	4.0	2.3	1.4	0.2	3.0	2.6	1.2	3.4	3.3	2.5	2.9
Frequency of tenseness / restlessness in last 2 weeks	4.2	6.6	16.2	2.5	2.9	2.9	1.5	3.1	2.3	2.0	2.3	4.0	-0.4	2.8	1.0	3.1	3.0	3.2	3.7	2.3	1.6	0.7	2.7	3.0	0.9	2.8	2.6	2.6	2.7
Illnesses of father: High blood pressure	4.2	5.1	8.7	2.7	2.6	2.5	2.4	2.7	3.0	2.5	2.4	1.7	-0.9	2.5	0.2	1.3	2.5	1.9	1.8	2.5	2.5	2.1	2.5	2.2	2.6	2.5	1.9	2.5	2.2
Respiratory disease	4.1	9.0	14.5	-3.1	-3.4	-3.8	-2.1	-3.5	-2.5	-2.9	-3.1	-3.5	0.6	-3.2	-1.2	-3.3	-3.5	-2.9	-3.8	-3.0	-2.4	-1.8	-3.5	-3.2	-2.1	-3.3	-3.1	-3.2	-3.4
Cardiovascular Disease	4.0	13.4	67.6	4.4	4.1	4.5	2.6	3.8	8.2	4.3	4.0	2.3	-1.4	4.0	0.7	2.0	3.5	1.9	2.0	4.1	4.4	3.0	3.5	3.3	3.4	3.1	2.5	4.0	2.9
Hayfever, allergic rhinitis or eczema	4.0	8.8	13.5	-3.4	-3.2	-3.5	-3.0	-2.8	-3.2	-3.4	-3.5	-1.4	1.3	-3.4	-1.5	-3.0	-3.3	-2.8	-3.1	-3.2	-2.9	-1.5	-3.2	-2.9	-2.3	-2.6	-3.5	-3.4	-3.7
Hearing aid user	4.0	4.5	8.1	2.2	2.3	2.6	1.5	2.1	1.5	1.4	2.4	1.6	0.2	2.4	2.6	2.6	2.5	2.9	2.5	2.3	1.9	1.1	2.2	2.5	0.9	1.9	2.6	2.4	2.1
Noisy workplace	3.9	4.8	7.2	2.3	2.4	2.4	2.0	2.2	2.2	1.8	2.2	2.4	-1.2	2.4	-0.5	1.8	2.4	1.5	1.8	2.5	2.4	2.7	2.7	2.6	2.7	2.6	1.1	2.4	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.9	8.2	20.9	3.1	3.5	3.6	1.5	3.4	4.6	2.4	2.9	3.8	-0.9	3.1	-0.5	2.2	3.0	2.7	3.2	2.8	2.4	0.8	3.0	2.7	1.9	3.6	2.8	3.0	2.9
Frequency of tiredness / lethargy in last 2 weeks	3.8	6.1	15.3	2.5	2.9	3.0	1.2	3.0	2.0	2.1	2.4	3.9	-2.0	2.7	-0.2	2.3	2.8	2.5	3.3	2.3	1.7	0.9	2.5	2.6	1.6	3.1	2.3	2.5	2.9
LDL Cholesterol	3.7	5.9	17.6	-3.0	-2.7	-2.6	-2.1	-1.8	-0.6	-1.0	-2.8	-1.4	0.1	-2.8	-2.4	-1.9	-2.8	-3.3	-2.8	-2.8	-2.5	-0.3	-2.7	-2.2	-1.4	-2.3	-4.2	-3.0	-2.9
Lung FVC	3.7	18.8	38.6	4.1	4.9	5.0	2.6	5.5	4.4	2.1	4.0	5.8	-1.5	4.6	2.8	5.7	4.9	5.8	6.2	3.9	2.6	1.7	4.5	5.3	1.5	4.6	4.4	4.3	4.3
Breast Cancer	3.6	8.7	26.7	-3.0	-3.3	-2.3	-5.2	-3.0	1.6	-2.2	-3.1	-2.6	1.4	-3.3	0.4	-2.6	-3.4	-2.8	-3.2	-3.1	-2.7	-2.1	-3.7	-3.1	-2.9	-3.7	-2.6	-3.1	-3.1
Allergy or Eczema	3.6	9.5	17.5	-3.4	-3.4	-3.7	-2.8	-2.7	-4.2	-3.3	-3.5	-2.1	1.2	-3.4	-1.1	-3.0	-3.4	-3.1	-3.5	-3.3	-2.9	-1.0	-3.3	-2.9	-1.9	-3.0	-3.9	-3.5	-3.6
Pulse wave peak to peak time	3.6	4.2	8.3	-2.3	-2.4	-2.4	-1.4	-2.2	-1.4	-1.4	-2.2	-2.1	2.1	-2.3	-0.7	-1.6	-2.4	-2.6	-2.6	-2.2	-1.9	0.1	-2.2	-1.9	-0.6	-2.3	-2.9	-2.3	-2.0
Medication: Metformin	3.5	4.9	12.2	2.8	2.5	2.2	2.4	2.4	1.7	2.5	2.6	1.3	-2.0	2.4	-1.0	0.9	2.2	0.2	0.7	2.7	3.1	3.5	2.5	2.2	3.1	1.8	0.4	2.5	1.9
High blood pressure (mother)	3.5	4.9	16.1	2.5	2.4	2.8	1.2	1.6	4.0	2.6	2.5	1.7	-1.2	2.4	0.8	1.4	2.3	1.8	1.3	2.6	2.6	1.6	2.3	2.1	2.5	2.6	2.0	2.5	1.9
Illnesses of siblings	3.5	4.9	17.4	-2.5	-2.6	-2.8	-0.3	-2.3	-4.2	-2.1	-2.2	-3.0	1.2	-2.5	-0.8	-1.5	-2.4	-2.1	-2.2	-2.2	-2.1	-1.2	-2.2	-2.3	-1.1	-2.3	-2.0	-2.3	-1.7
Medication: Bendroflumethiazide	3.5	5.3	17.0	2.7	2.4	2.9	1.3	2.4	4.1	2.5	2.7	1.5	-1.0	2.5	0.9	1.6	2.3	1.6	1.3	2.7	2.8	2.3	2.4	2.3	2.5	2.4	1.6	2.6	1.8
Height	3.3	64.1	163.8	-10.1	-9.9	-9.1	-5.0	-7.3	0.6	-9.0	-9.6	-4.3	12.8	-9.7	0.6	-3.5	-8.9	-5.1	-5.8	-9.9	-10.6	-5.3	-9.1	-7.2	-7.5	-7.3	-7.4	-9.6	-8.7
Waist circumference	3.3	12.2	18.5	3.7	4.0	3.3	4.2	3.4	4.2	3.0	3.8	3.5	-2.8	4.0	-0.5	2.3	3.9	2.5	3.2	3.9	3.8	2.5	4.0	3.3	3.6	4.3	3.0	3.9	3.6
Mother’s age at death	3.3	4.1	8.6	-2.5	-2.4	-2.0	-2.7	-2.6	-1.4	-2.9	-2.4	-2.6	0.2	-2.3	-0.6	-1.5	-2.0	-0.9	-1.5	-2.1	-2.0	-1.9	-2.0	-2.0	-2.1	-2.0	-1.2	-2.2	-2.1
Diabetes (self-reported)	3.2	5.0	12.2	2.6	2.3	2.0	2.1	1.8	2.4	3.5	2.4	0.8	-2.6	2.2	-2.0	-0.1	1.9	-0.3	0.0	2.6	3.4	3.4	2.4	1.8	3.5	1.7	0.1	2.4	1.7
Falls in the last year	3.2	4.4	8.0	2.5	2.5	2.2	2.0	2.5	0.7	1.8	2.3	2.2	-1.0	2.5	1.0	1.7	2.4	2.1	2.4	2.2	1.9	0.6	2.5	1.7	1.7	2.8	2.6	2.3	2.0
Mouth/teeth dental problems: Dentures	3.2	5.3	10.5	2.3	2.6	1.9	2.9	2.4	0.5	1.1	2.4	2.3	-2.0	2.6	-1.1	1.7	2.7	1.5	2.6	2.4	2.1	1.2	2.9	2.0	2.7	3.2	2.5	2.5	3.2
Leg fat mass (right)	3.2	12.3	20.0	3.8	4.0	3.5	3.9	3.1	3.8	3.8	3.8	3.2	-3.9	4.0	-1.3	1.7	3.8	2.0	2.4	4.0	4.1	3.1	4.0	3.2	4.3	4.5	2.4	3.9	3.3
Commuting to job workplace: Walk	3.2	3.5	6.3	-2.3	-2.1	-1.9	-2.5	-1.9	2.1	-1.6	-2.2	-1.0	0.4	-2.1	-0.5	-1.4	-1.9	-1.1	-1.2	-2.1	-2.1	-2.0	-1.9	-2.0	-2.5	-1.8	-1.5	-2.1	-2.1
Systolic blood pressure, automated reading	3.1	9.1	52.0	3.4	3.1	3.3	1.8	2.6	7.2	3.0	3.3	1.1	-0.3	3.2	0.0	1.4	2.8	1.5	0.9	3.5	3.9	3.1	3.0	2.6	4.1	2.7	2.1	3.3	2.6
Asthma	3.1	6.1	8.5	-2.7	-2.8	-2.9	-2.6	-2.9	-1.7	-2.5	-2.6	-2.4	0.6	-2.7	-1.0	-2.4	-2.8	-2.3	-2.6	-2.6	-2.3	-1.4	-2.9	-2.5	-2.2	-2.8	-2.7	-2.7	-2.7
Asthma (self-reported)	3.1	6.1	8.4	-2.6	-2.8	-2.8	-2.6	-2.9	-1.8	-2.4	-2.6	-2.6	0.2	-2.7	-1.3	-2.7	-2.8	-2.6	-2.7	-2.6	-2.2	-1.6	-2.9	-2.7	-2.1	-2.7	-2.6	-2.7	-2.5
Medication: Allopurinol	3.0	3.9	7.6	2.5	2.4	2.5	0.9	2.0	2.5	2.1	2.3	1.4	-0.6	2.4	0.1	0.8	2.1	1.6	1.1	2.5	2.8	2.0	2.2	2.0	2.1	1.9	1.5	2.4	1.6
Family relationship satisfaction	3.0	3.7	6.8	-2.2	-2.0	-1.8	-2.0	-2.6	-0.7	-2.1	-2.1	-1.6	-0.6	-2.1	-1.7	-2.2	-2.1	-2.2	-1.7	-2.1	-1.9	-1.6	-2.0	-2.6	-1.3	-1.3	-1.8	-2.2	-1.7
Back pain experienced in last month	3.0	4.4	8.6	1.8	2.2	2.1	2.0	2.9	2.5	0.8	2.0	2.9	-0.4	2.2	0.6	2.4	2.3	2.3	2.6	1.9	1.4	0.7	2.2	2.3	1.7	2.4	2.4	2.1	2.7
Leg fat mass (left)	3.0	11.6	19.2	3.7	3.9	3.4	3.8	3.0	3.8	3.6	3.7	3.1	-3.9	3.8	-1.4	1.6	3.6	1.9	2.4	3.9	4.0	2.9	3.9	3.0	4.2	4.4	2.3	3.8	3.2
Medication for cholesterol	2.9	4.4	12.7	-2.3	-2.1	-2.1	-2.4	-2.9	-3.6	-2.8	-2.3	-1.9	-0.2	-2.2	-0.4	-1.7	-2.0	-1.5	-1.2	-2.3	-2.3	-2.3	-2.0	-2.3	-2.0	-1.8	-1.0	-2.2	-1.5
Smoking Status	2.8	6.7	13.7	2.2	2.6	2.9	0.9	3.1	-0.2	1.6	2.5	3.7	-2.5	2.7	1.1	2.7	3.0	3.4	3.6	2.4	1.8	0.6	3.0	2.7	1.5	3.1	3.3	2.7	3.0
Standing height	2.8	28.1	83.2	-6.6	-6.6	-6.1	-3.4	-4.9	-0.0	-5.7	-6.4	-3.3	9.1	-6.4	0.5	-2.3	-5.8	-3.4	-3.9	-6.4	-6.8	-3.3	-5.8	-4.6	-5.1	-5.2	-4.8	-6.2	-5.6
Pulse wave reflection index	2.8	3.4	6.5	2.0	2.1	2.3	1.4	1.8	-0.0	2.1	2.1	1.4	-0.9	2.2	0.2	1.4	2.2	2.3	2.0	2.2	2.1	0.2	2.0	1.8	1.1	2.1	2.6	2.2	2.0
Qualifications: nursing, teaching	2.8	4.3	11.9	-1.8	-2.4	-2.3	-0.7	-2.2	-1.7	-0.9	-1.9	-3.5	2.0	-2.3	1.5	-1.5	-2.4	-2.6	-3.0	-1.9	-1.4	0.6	-2.2	-1.7	-0.7	-3.0	-2.5	-2.0	-2.1
Worry (Nagel 2018)	2.7	5.6	9.8	-2.7	-2.8	-2.3	-3.1	-2.2	-2.4	-2.7	-2.8	-0.6	2.4	-2.8	0.3	-0.9	-2.5	-2.0	-2.1	-2.8	-2.9	-0.8	-2.5	-1.7	-2.0	-2.3	-2.9	-2.8	-2.9
Major Depression (MDD)	2.7	3.2	8.8	1.4	1.5	2.2	0.5	2.2	-0.3	1.0	1.7	2.4	-1.0	1.6	1.9	3.0	1.8	2.6	2.1	1.5	1.0	1.5	1.7	2.6	1.4	2.4	1.3	1.7	1.5
Mean Putamen Volume	2.7	3.1	6.5	-1.7	-1.6	-2.3	-0.9	-2.4	-2.5	-1.2	-1.8	-2.5	-0.8	-1.7	-2.5	-2.4	-1.7	-2.2	-1.6	-1.7	-1.4	-1.1	-1.6	-2.3	-0.3	-1.4	-1.4	-1.8	-0.8
Loud music exposure frequency	2.7	3.0	10.4	1.2	1.9	1.6	0.3	1.9	1.4	-0.8	1.0	2.7	-0.0	1.7	1.3	1.9	2.1	2.9	3.2	1.2	0.4	-0.9	1.8	1.6	-0.4	1.9	2.8	1.4	1.8
Medication: Amlodipine	2.7	3.8	8.5	2.1	2.1	2.1	1.3	1.8	2.9	1.9	2.0	1.6	-2.7	2.0	-1.3	0.7	1.8	0.4	0.7	2.2	2.5	2.4	2.2	1.9	2.8	2.2	0.7	2.1	1.5
Chronic bronchitis/emphysema (mother)	2.7	3.1	7.7	2.2	1.9	1.5	1.8	1.8	0.7	1.8	2.1	1.2	0.4	1.9	0.0	0.9	1.9	0.4	0.7	2.2	2.4	2.6	2.2	1.7	2.8	1.8	1.0	2.1	1.9
Systolic Blood Pressure	2.6	13.2	79.6	4.2	3.7	4.3	1.4	3.6	8.9	3.9	4.0	1.4	0.0	3.7	0.8	1.5	3.3	2.0	1.3	4.1	4.7	3.4	3.6	3.0	4.2	2.8	2.9	3.9	3.1
Knee pain experienced in last month	2.6	4.0	12.3	1.0	1.4	1.6	0.9	2.5	-0.3	0.2	1.4	3.1	0.6	1.5	3.5	3.0	2.1	3.5	3.4	1.3	0.3	-0.5	1.6	2.1	-0.4	1.9	2.9	1.6	1.9
Diabetes diagnosed by doctor	2.6	4.2	12.0	2.3	2.0	1.8	2.2	1.7	1.8	3.0	2.1	1.1	-2.1	1.9	-2.2	0.1	1.6	-0.6	-0.1	2.4	3.0	3.4	2.1	1.8	3.5	1.8	-0.3	2.1	1.5
Medication: Lisinopril	2.6	3.3	21.7	2.1	1.8	2.0	1.0	1.9	4.7	1.3	2.0	0.8	-0.7	1.9	0.2	0.6	1.9	0.8	1.0	2.2	2.5	1.8	1.9	1.7	1.5	1.1	1.3	2.2	1.5
Time employed in main current job	2.5	2.8	7.2	1.3	1.4	1.8	0.9	1.4	1.0	1.1	1.6	1.8	0.1	1.7	2.7	2.5	2.0	2.4	2.3	1.7	1.2	0.9	1.8	2.0	0.6	2.0	1.9	1.8	1.3
Pulse wave Arterial Stiffness index	2.5	3.0	6.8	1.8	1.9	2.0	1.3	1.8	1.5	1.0	1.7	1.9	-1.5	1.9	0.8	1.4	1.9	2.3	2.4	1.8	1.4	-0.4	1.8	1.6	0.2	2.0	2.6	1.9	1.6
Ever depressed for a whole week	2.4	2.9	5.1	2.1	2.0	2.3	0.9	1.7	0.9	1.7	1.9	1.3	-1.8	1.9	0.8	1.5	1.9	1.3	1.5	1.8	1.6	1.4	2.0	1.6	2.0	2.0	1.7	1.8	1.9
Qualifications: CSEs or equivalent	2.3	3.1	6.6	1.8	2.2	1.6	2.1	2.2	0.3	1.9	1.8	2.0	-2.6	1.8	-1.9	1.1	1.7	0.3	2.1	1.6	1.3	0.3	1.7	1.2	1.5	2.1	1.5	1.7	2.5
Hair/balding pattern: Pattern 3	2.3	3.4	9.2	-1.2	-1.6	-1.6	-1.0	-1.4	-2.6	-0.7	-1.5	-2.5	-1.0	-1.7	-1.6	-1.9	-2.2	-3.0	-2.8	-1.5	-0.8	0.6	-1.9	-1.4	-0.6	-2.6	-3.0	-1.6	-1.8
Frequency of depressed mood in last 2 weeks	2.2	3.1	19.0	1.3	1.9	2.0	0.3	1.9	1.3	0.8	1.1	4.4	-0.9	1.6	0.3	2.6	1.7	2.6	2.9	1.0	0.1	-0.7	1.3	2.0	-0.5	2.3	1.4	1.3	1.1
Arm fat mass (right)	2.2	9.0	14.8	3.2	3.4	2.7	3.6	2.7	3.4	3.2	3.3	2.8	-3.1	3.3	-1.3	1.2	3.2	1.5	2.0	3.4	3.5	2.7	3.4	2.6	3.8	3.8	2.0	3.3	2.9
Suffer from ‘nerves’	2.2	3.4	5.7	-2.2	-2.0	-2.0	-2.3	-1.9	-1.5	-2.1	-2.3	0.1	1.5	-2.1	-0.4	-0.9	-2.0	-1.5	-1.5	-2.1	-2.2	-1.3	-2.1	-1.5	-2.0	-1.6	-2.2	-2.1	-2.4
Severe depression (siblings)	2.1	2.4	4.3	1.6	1.8	1.6	1.3	1.6	0.7	0.0	1.6	1.8	-0.9	1.7	1.5	1.7	1.9	1.7	1.9	1.6	1.2	0.4	1.8	1.5	1.0	1.9	2.1	1.7	1.6
Hand grip strength (right)	2.1	5.7	12.6	2.3	2.5	2.5	1.7	2.5	2.5	0.7	2.3	2.7	0.6	2.6	1.6	3.0	2.8	3.6	3.2	2.4	1.7	0.6	2.5	2.8	1.0	2.5	3.0	2.5	2.3
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	6.8	-2.2	-1.9	-2.0	-0.9	-1.7	-2.2	-2.6	-2.1	-1.0	0.4	-1.9	-0.2	-0.4	-1.7	-1.3	-1.1	-2.0	-2.2	-0.2	-1.7	-1.2	-1.2	-1.2	-2.3	-2.0	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.3	6.6	-1.6	-1.7	-1.0	-1.6	-1.3	-0.1	-1.6	-1.8	-0.7	1.2	-1.6	1.7	-0.3	-1.6	-0.0	-0.8	-1.8	-1.9	-1.3	-1.7	-0.9	-2.6	-1.8	-1.2	-1.7	-2.1
Arm fat mass (left)	2.1	8.6	14.3	3.2	3.3	2.7	3.6	2.6	3.2	3.2	3.3	2.6	-3.1	3.3	-1.3	1.1	3.1	1.4	1.9	3.4	3.5	2.7	3.4	2.5	3.8	3.8	1.9	3.2	2.8
Waist Hip Ratio (WHR)	2.0	8.9	19.4	3.0	3.7	2.9	2.0	2.9	2.5	1.5	2.9	4.4	-3.4	3.6	1.1	2.8	3.5	3.5	3.8	3.2	2.6	0.4	3.2	3.2	1.0	3.4	3.2	3.3	2.5
Taking other prescription medications	2.0	3.0	6.6	-2.3	-1.9	-2.0	-1.3	-1.7	-0.8	-2.5	-2.2	-0.0	0.6	-2.0	-0.9	-0.9	-1.8	-0.8	-0.7	-2.2	-2.6	-1.8	-2.0	-1.6	-2.1	-0.9	-1.6	-2.1	-2.1
Hearing difficulty/problems with background noise	2.0	3.2	5.4	1.8	2.0	1.5	2.3	1.7	-0.4	1.3	1.6	1.9	-1.3	1.9	0.9	1.9	2.2	1.9	2.3	1.8	1.3	1.3	2.2	2.0	1.6	2.3	1.8	1.8	2.0
Hearing difficulty/problems: Yes	1.9	2.9	4.9	2.1	2.2	1.5	1.9	1.8	0.8	1.8	1.8	1.8	-1.4	1.9	-0.3	0.7	2.0	1.2	1.5	2.0	2.0	1.3	1.9	1.7	1.8	2.0	1.4	1.9	2.0
Eye problems/disorders: Diabetes related eye disease	1.9	2.1	4.2	1.7	1.6	1.5	1.6	1.2	1.9	1.0	1.6	-0.3	-1.1	1.6	-0.6	0.7	1.6	1.0	0.8	1.8	2.0	1.5	1.9	1.3	2.0	1.3	1.3	1.7	1.6
Eye problems/disorders: None of the above	1.9	2.2	5.9	-1.9	-1.5	-1.2	-1.9	-0.6	-1.2	-1.2	-1.8	0.4	0.2	-1.7	-1.3	-0.6	-1.6	-1.8	-0.2	-2.0	-2.4	-1.8	-1.8	-1.5	-1.7	-0.7	-1.4	-1.8	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.9	4.0	17.6	-2.5	-2.6	-2.0	-1.2	-1.1	1.2	-1.4	-2.3	-1.1	4.2	-2.5	0.6	-0.2	-2.2	-1.6	-1.5	-2.5	-2.6	-0.3	-2.1	-1.3	-1.6	-2.2	-2.4	-2.3	-1.9
Unable to work because of sickness or disability	1.9	2.5	7.0	1.6	1.9	1.4	1.5	2.1	0.4	0.4	1.6	2.6	-2.0	1.8	-0.4	1.4	1.7	1.3	2.2	1.5	1.1	0.3	1.6	1.6	0.7	2.0	1.5	1.7	1.8
Pain experienced in last month	1.9	3.2	8.4	-1.4	-1.9	-1.9	-0.7	-2.3	-0.7	-0.1	-1.3	-2.4	0.0	-1.9	-1.3	-2.9	-2.1	-2.9	-2.8	-1.4	-0.7	-0.6	-1.8	-2.4	-0.7	-1.9	-2.0	-1.7	-2.0
Fasting Glucose	1.8	2.2	5.3	2.1	1.9	1.0	1.8	1.2	-0.0	2.3	1.8	1.0	-1.3	1.9	-0.2	0.2	1.8	1.3	0.8	2.0	2.2	0.9	1.6	1.3	1.1	1.3	1.2	1.7	0.9
Arm fat percentage (right)	1.8	7.1	17.5	2.9	3.0	2.1	3.3	2.1	2.4	3.1	2.9	2.1	-4.2	2.9	-2.1	0.4	2.6	0.5	1.2	3.0	3.4	2.7	2.9	2.1	3.8	3.2	1.1	2.9	2.5
Number of full brothers	1.8	2.2	6.0	1.5	1.6	1.2	1.3	1.8	1.4	1.5	1.7	2.5	-0.2	1.7	0.6	0.9	1.7	1.2	1.3	1.7	1.7	1.0	1.6	1.4	1.3	2.2	1.2	1.7	1.2
Migraine (self-reported)	1.8	2.3	4.7	-1.7	-1.7	-1.4	-1.8	-0.9	-0.8	-1.5	-1.9	-0.4	2.1	-1.7	0.9	-0.2	-1.5	-0.9	-1.1	-1.9	-2.2	-0.5	-1.6	-0.9	-1.7	-1.6	-1.8	-1.9	-2.0
Miserableness	1.8	3.2	13.0	1.8	1.9	2.0	0.4	1.5	2.2	1.5	1.4	3.6	-0.4	1.9	1.5	2.2	1.9	2.0	2.1	1.7	1.2	1.0	1.7	2.3	0.2	2.3	1.0	1.8	0.6
Arm fat-free mass (left)	1.8	9.0	15.9	2.8	3.2	3.1	2.6	3.5	4.0	2.2	3.0	3.8	-0.3	3.2	1.1	2.9	3.5	3.6	4.0	2.9	2.1	0.5	3.2	2.9	1.6	3.6	3.7	3.1	3.2
Arm fat percentage (left)	1.7	6.8	18.1	2.9	2.9	2.0	3.4	1.9	2.1	3.0	2.8	1.9	-4.3	2.8	-2.2	0.2	2.4	0.4	0.9	2.9	3.4	2.9	2.8	1.9	3.9	3.2	1.0	2.7	2.3
Long-standing illness, disability or infirmity	1.7	2.7	5.2	-2.1	-1.9	-1.8	-1.5	-1.6	-0.7	-2.2	-2.0	-0.0	0.2	-2.0	-1.4	-1.2	-1.7	-1.6	-0.8	-2.1	-2.3	-1.7	-1.6	-1.9	-1.7	-0.9	-1.4	-1.9	-1.6
Illnesses of father: None of the above (group 1)	1.7	2.1	5.3	-1.5	-1.5	-1.2	-1.3	-0.8	-2.3	-0.8	-1.4	0.6	2.1	-1.6	1.0	0.0	-1.5	-0.4	-0.7	-1.7	-2.0	-1.4	-1.6	-0.8	-2.2	-1.3	-1.2	-1.5	-1.9
Arm predicted mass (left)	1.7	8.7	15.5	2.6	3.1	3.0	2.5	3.5	3.9	2.1	2.8	3.9	0.1	3.1	1.3	2.9	3.4	3.6	3.9	2.8	2.0	0.5	3.1	2.9	1.5	3.6	3.6	3.1	3.0
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.5	8.7	1.8	2.1	1.8	2.0	1.8	3.0	1.4	1.8	1.6	0.2	2.1	1.0	2.5	2.0	1.9	2.2	1.8	1.4	1.6	1.7	2.5	1.4	1.5	1.5	2.0	2.2
Impedance of leg (left)	1.6	7.7	12.8	-2.9	-3.2	-2.7	-3.4	-3.5	-2.0	-2.1	-3.0	-3.4	1.8	-3.1	-0.9	-2.3	-3.2	-2.9	-3.3	-2.8	-2.3	-0.8	-2.9	-2.5	-2.0	-3.6	-3.2	-2.9	-3.1
Length of working week for main job	1.6	1.8	6.0	1.2	1.2	1.0	2.4	1.5	-0.7	1.7	1.4	0.8	-0.7	1.2	-0.2	1.2	1.4	1.0	1.3	1.3	1.2	1.1	1.7	1.1	1.9	1.7	1.3	1.3	1.7
Comparative body size at age 10	1.6	4.4	10.2	2.2	2.4	2.3	1.9	2.1	3.2	2.8	2.3	2.0	-1.2	2.4	0.1	1.7	2.2	1.9	2.1	2.2	2.0	1.3	2.1	2.2	1.7	2.2	1.9	2.3	2.1
Irritability	1.6	2.7	5.8	1.6	1.8	2.0	0.2	1.7	2.2	-0.1	1.3	2.3	-0.9	1.7	2.3	2.0	1.9	2.4	2.2	1.5	1.0	0.9	1.7	2.2	-0.0	1.3	1.5	1.6	1.0
Alzheimer’s Disease (in father)	1.5	1.6	4.0	1.1	1.6	1.5	-0.4	1.6	1.8	0.9	1.1	2.0	-1.3	1.3	-1.0	0.4	1.3	1.0	1.5	1.2	1.2	-0.3	1.3	1.0	0.8	1.5	1.4	1.3	1.7
Alzheimer’s Disease (including proxy)	1.5	2.2	4.5	1.2	1.6	1.5	0.6	1.6	0.9	0.8	1.5	1.8	-0.7	1.6	-0.6	1.7	1.8	1.1	1.8	1.6	1.3	1.0	1.8	1.6	1.7	1.9	1.3	1.6	2.1
Hand grip strength (left)	1.5	3.9	8.4	1.8	2.0	2.0	1.4	1.8	1.9	0.8	1.8	2.4	0.5	2.0	1.8	2.7	2.3	2.9	2.9	1.8	1.1	0.2	2.0	2.2	0.4	2.2	2.7	2.0	1.9
Father’s age at death	1.5	1.9	4.9	-1.8	-1.7	-1.8	-1.3	-2.1	-1.8	-2.2	-1.6	-0.7	0.1	-1.6	-0.5	-1.7	-1.2	-0.3	-1.2	-1.3	-1.1	-1.3	-1.1	-1.4	-1.2	-1.0	-0.6	-1.4	-1.6
Lung cancer (father)	1.5	1.8	3.7	1.6	1.5	1.7	0.6	1.8	0.2	1.9	1.5	1.4	-0.4	1.4	-0.0	1.5	1.3	0.9	0.8	1.5	1.4	1.6	1.3	1.8	1.6	1.2	0.6	1.5	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	30.3	1.5	1.9	2.5	0.7	2.9	5.5	1.4	1.3	3.4	1.9	1.6	0.5	3.0	1.8	2.6	2.8	1.2	0.4	0.7	1.7	2.5	0.2	2.1	1.3	1.6	1.4
Arm fat-free mass (right)	1.5	7.4	13.6	2.5	2.9	2.9	2.4	3.2	3.7	2.0	2.6	3.4	-0.2	2.9	1.2	2.7	3.2	3.3	3.6	2.6	1.9	0.5	2.9	2.6	1.5	3.3	3.4	2.8	2.8
Depressed Affect (Nagel 2018)	1.4	3.0	19.5	1.6	2.0	1.7	0.3	1.9	1.3	1.7	1.3	4.4	-1.2	1.7	0.8	1.7	1.8	1.8	2.4	1.3	0.8	0.5	1.6	2.0	-0.0	2.4	0.8	1.5	0.6
Reaction Time	1.4	2.6	6.3	1.6	1.9	1.3	2.1	2.5	-1.4	2.3	1.6	1.9	-0.7	1.8	1.8	1.8	1.8	1.5	2.1	1.4	0.9	0.0	1.7	1.2	0.4	1.5	1.8	1.5	1.5
Chronotype (morning person)	1.4	3.2	7.9	-2.0	-2.2	-1.3	-2.8	-1.6	0.4	-0.2	-1.9	-1.7	1.2	-2.1	0.3	-1.4	-2.1	-1.7	-1.7	-1.9	-1.9	-1.9	-2.2	-2.1	-2.0	-1.9	-1.4	-2.0	-2.1
Impedance of leg (right)	1.4	6.7	11.8	-2.6	-3.0	-2.5	-3.0	-3.3	-1.9	-1.7	-2.7	-3.3	2.1	-2.9	-0.7	-1.9	-3.0	-3.0	-3.3	-2.6	-2.1	-0.2	-2.7	-2.2	-1.5	-3.4	-3.3	-2.7	-2.7
Stomach or abdominal pain in last month	1.4	1.7	8.1	-1.5	-0.9	-1.2	-0.2	-1.4	-1.0	-2.8	-1.5	-0.0	-1.0	-1.2	-2.5	-0.6	-1.0	-0.6	0.2	-1.5	-1.8	-2.3	-1.1	-1.4	-1.0	-0.2	-0.4	-1.3	-0.2
Nervous feelings	1.4	2.7	6.3	-1.8	-1.9	-1.5	-2.5	-1.8	-0.6	-1.3	-1.9	-1.1	1.1	-1.9	-0.3	-1.2	-1.8	-0.8	-1.5	-1.8	-1.7	-1.6	-1.8	-1.5	-2.0	-2.0	-1.4	-1.9	-1.9
Breastfed as a baby	1.4	1.7	3.9	-1.6	-1.4	-1.3	-1.0	-1.0	-1.8	-2.0	-1.2	-1.2	-1.4	-1.5	-1.6	-0.7	-1.4	-1.8	-1.1	-1.4	-1.5	-0.8	-1.3	-1.4	-0.1	-0.8	-1.3	-1.4	-0.7
Number of children fathered	1.4	1.6	4.0	-1.0	-1.4	-1.6	0.3	-1.8	-1.5	-0.9	-1.1	-2.0	1.2	-1.2	-0.7	-1.8	-1.3	-1.3	-1.6	-0.9	-0.4	-0.7	-1.3	-1.5	-0.9	-1.3	-1.1	-1.1	-1.4
Mean time to correctly identify matches	1.4	2.7	5.7	1.6	1.9	1.4	2.0	2.4	-1.4	1.8	1.7	1.7	-0.1	1.8	1.8	2.2	1.9	1.4	1.9	1.6	1.1	0.9	1.8	1.6	1.1	1.6	1.5	1.6	1.5
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	4.5	-1.4	-1.7	-1.7	-1.1	-1.2	-0.2	0.2	-1.5	-1.2	1.7	-1.7	-0.2	-1.6	-1.8	-1.8	-2.1	-1.5	-1.2	0.2	-1.6	-1.3	-0.8	-1.7	-2.1	-1.6	-2.1
Medication: Gliclazide	1.4	1.6	4.0	1.4	1.3	1.2	2.0	1.2	1.0	1.4	1.4	1.1	-1.7	1.3	-0.8	0.7	1.2	-0.2	0.9	1.3	1.3	1.3	1.4	0.9	1.7	1.4	0.6	1.3	1.6
Crohns Disease (2012)	1.3	2.1	10.4	-1.0	-1.2	-1.5	0.0	-1.2	1.2	-0.7	-1.3	-2.1	3.2	-1.1	-0.6	-1.8	-1.3	-1.7	-1.4	-1.0	-0.6	-1.2	-1.4	-1.5	-1.8	-2.0	-1.2	-1.1	-1.3
Maternal smoking around birth	1.3	1.9	4.3	1.7	1.6	1.6	0.4	1.3	-0.1	2.1	1.5	1.7	-1.9	1.5	-0.5	1.1	1.3	0.0	0.9	1.3	1.2	1.5	1.5	1.2	1.8	1.9	0.4	1.4	1.1
Pain all over the body in last month	1.3	1.3	3.4	1.6	1.4	1.3	1.1	1.0	1.3	1.6	1.3	0.1	0.5	1.4	0.5	0.7	1.1	0.2	0.1	1.4	1.6	1.8	1.3	1.1	1.7	0.7	0.2	1.2	0.8
Medication: Lansoprazole	1.3	1.5	3.0	1.3	1.4	1.3	1.6	1.3	-0.2	0.6	1.4	0.9	-0.7	1.4	1.0	0.9	1.4	1.3	0.8	1.4	1.5	1.7	1.5	1.6	1.4	1.4	0.7	1.4	0.7
Body fat percentage	1.3	5.2	14.6	2.4	2.4	1.6	3.1	1.3	2.3	2.7	2.3	1.3	-3.8	2.3	-2.6	-0.1	2.0	-0.1	0.4	2.5	3.0	2.7	2.4	1.5	3.6	2.7	0.4	2.3	1.8
Arm predicted mass (right)	1.3	6.8	13.0	2.4	2.7	2.7	2.5	3.0	3.6	1.8	2.5	3.2	0.2	2.7	1.3	2.6	3.0	3.3	3.4	2.5	1.8	0.4	2.8	2.5	1.4	3.2	3.3	2.6	2.6
Guilty feelings	1.3	2.0	7.2	1.2	1.4	1.5	0.6	1.7	1.7	0.6	1.0	2.7	0.3	1.2	2.7	2.1	1.3	1.9	1.7	0.9	0.4	0.7	1.2	1.7	0.1	1.3	1.1	1.1	0.7
Crohns Disease (2017)	1.2	2.6	11.8	-1.3	-1.3	-1.7	0.5	-1.1	1.6	-1.3	-1.5	-1.5	3.4	-1.3	-0.7	-1.8	-1.5	-1.9	-1.0	-1.3	-1.1	-1.8	-1.7	-1.9	-2.3	-2.1	-1.2	-1.3	-1.2
Ever had hysterectomy (womb removed)	1.2	1.3	3.8	0.8	1.1	1.0	1.2	1.6	-1.0	0.0	0.8	1.9	-0.6	1.0	1.6	2.0	1.2	1.5	1.8	0.7	0.1	0.1	1.0	1.3	-0.0	1.1	1.2	0.9	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	4.0	1.3	1.5	1.3	0.5	1.4	1.0	1.0	1.1	1.1	-0.7	1.3	1.3	0.7	1.4	1.4	1.5	1.2	1.1	-0.7	1.3	0.8	-0.2	0.9	2.0	1.3	0.9
Type 2 Diabetes (T2D) (2018)	1.1	2.1	6.9	1.6	1.3	1.1	0.8	1.0	2.4	2.6	1.3	0.7	-1.5	1.0	-2.2	-0.7	0.6	-1.3	-1.0	1.5	2.2	2.1	1.0	0.8	2.4	0.9	-0.8	1.2	0.6
Weight	1.1	5.5	14.6	2.2	2.5	2.0	3.3	2.4	3.8	2.2	2.4	2.7	-0.8	2.5	-0.3	1.6	2.5	1.8	2.2	2.4	2.1	1.7	2.6	2.1	2.5	3.2	1.9	2.4	2.2
Whole body fat mass	1.1	4.7	10.2	2.2	2.3	1.7	3.0	1.6	2.9	2.4	2.2	1.7	-2.7	2.3	-1.9	0.4	2.0	0.4	0.9	2.4	2.6	2.3	2.4	1.6	3.2	2.8	0.8	2.2	1.8
Had major operations	1.1	1.3	3.6	0.8	1.1	1.2	0.8	1.4	-0.0	0.1	0.9	1.9	-0.7	1.1	0.6	1.6	1.4	1.6	1.4	1.1	0.8	0.8	1.3	1.5	0.7	1.7	0.8	1.2	0.6
Average weekly champagne plus white wine intake	1.1	1.5	4.5	-1.4	-1.4	-1.6	0.2	-0.5	-1.1	-1.5	-1.5	-0.5	2.1	-1.4	0.9	-0.1	-1.3	-0.8	-1.0	-1.5	-1.5	-0.1	-1.3	-0.6	-0.9	-1.3	-1.5	-1.4	-1.1
Financial difficulties in last 2 years	1.0	1.4	11.7	-0.6	-0.1	0.2	-1.0	1.0	-0.7	-0.7	-0.5	3.4	0.1	-0.2	0.9	1.3	0.3	1.7	1.7	-0.5	-1.4	-2.0	0.0	0.3	-1.9	1.1	0.9	-0.2	-0.5
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	22.1	1.0	1.3	1.9	0.4	2.4	4.7	1.0	0.8	3.1	2.4	1.1	1.3	2.7	1.3	2.3	2.4	0.7	-0.0	0.7	1.2	2.2	-0.3	1.5	0.8	1.0	0.8
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	9.2	-0.5	-0.9	-0.6	-1.4	-1.5	-0.5	0.1	-0.2	-3.0	0.5	-0.7	-0.2	-1.1	-1.0	-1.7	-1.8	-0.3	0.3	-0.4	-1.0	-1.2	0.0	-1.8	-0.6	-0.5	-0.3
Loneliness, isolation	1.0	1.4	9.4	0.7	1.4	0.5	0.5	1.1	1.6	0.3	0.5	3.1	-1.3	1.1	-1.2	0.3	1.0	0.9	2.1	0.5	0.0	-1.7	0.6	0.3	-0.6	1.4	1.3	0.6	1.3
Eye problems/disorders: Cataract	1.0	1.2	5.7	1.4	0.8	0.8	0.4	0.5	-0.2	1.6	1.2	-0.5	0.7	1.0	1.6	-0.2	0.8	0.6	-0.8	1.3	2.0	2.4	0.9	1.1	1.5	-0.3	0.1	1.1	0.1
Commuting to job workplace: Cycle	1.0	1.2	2.5	-1.2	-1.0	-1.3	-0.6	-1.1	-0.5	-1.6	-1.4	-0.9	0.0	-1.2	-0.5	-0.7	-1.2	-0.8	-0.7	-1.4	-1.4	-0.6	-1.3	-0.9	-1.2	-1.1	-1.4	-1.4	-1.2
Cholesterol lowering medication	1.0	1.4	8.2	1.3	1.2	1.4	-0.0	1.1	2.9	2.1	1.2	0.3	-0.6	1.0	-1.4	-0.3	0.7	-0.6	-0.4	1.2	1.7	1.8	0.7	0.9	1.3	0.2	-0.6	1.0	0.5
Bipolar Disorder (2018)	0.9	1.4	8.3	-1.3	-1.2	-0.5	-1.2	-1.1	-2.9	-1.6	-1.1	-0.5	-1.5	-1.2	-0.8	-0.1	-1.1	-0.0	-0.2	-1.3	-1.5	-1.2	-1.0	-0.9	-1.2	-0.6	-0.7	-1.2	-0.9
Irritable Bowel Disease (IBD)	0.9	2.1	14.2	-1.0	-1.1	-1.5	1.3	-1.1	0.8	-1.2	-1.2	-1.8	3.8	-1.0	0.8	-0.8	-1.1	-1.6	-0.5	-1.1	-1.0	-0.9	-1.4	-1.2	-2.2	-2.3	-1.0	-1.0	-0.8
Medication for hormone replacement therapy	0.9	1.0	2.4	-1.2	-0.9	-1.1	-0.7	-0.1	-0.6	-1.6	-1.2	0.9	0.1	-1.1	-1.3	-0.5	-1.0	-0.4	-0.3	-1.2	-1.4	-1.3	-1.1	-0.8	-1.3	-0.5	-0.8	-1.1	-0.8
Diabetes (mother)	0.9	1.1	5.2	1.1	0.8	0.6	0.6	0.1	0.7	1.6	1.0	0.2	-1.6	0.8	-1.4	-0.5	0.4	-1.0	-0.9	1.1	1.6	1.7	0.8	0.5	2.3	0.9	-0.3	1.0	0.4
Had other major operations	0.9	1.1	15.5	-1.0	-1.0	-1.1	-0.1	-0.4	-3.9	-1.1	-0.9	0.2	-0.3	-0.9	-0.8	-0.7	-0.7	-0.6	-0.7	-0.9	-0.9	-0.1	-0.5	-0.7	0.2	0.4	-0.8	-0.9	-0.9
Pulse rate	0.9	1.5	4.2	-1.2	-1.1	-0.8	-1.2	-1.1	1.0	-2.1	-1.4	0.2	-1.3	-1.2	-1.2	-1.2	-1.3	-0.8	-0.7	-1.4	-1.4	-2.0	-1.3	-1.4	-1.5	-0.7	-0.8	-1.3	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	4.2	-1.2	-0.9	-0.7	-1.2	-0.6	-1.7	-1.5	-1.2	-0.2	0.2	-0.9	0.1	0.1	-0.8	-0.0	0.5	-1.2	-1.7	-2.0	-1.2	-0.9	-1.8	-0.6	0.0	-1.0	-0.3
Tense / ‘highly strung’	0.9	1.5	5.7	-1.4	-1.1	-0.6	-1.6	-0.4	-0.9	-2.4	-1.5	1.2	0.6	-1.3	0.4	0.8	-1.1	0.1	0.3	-1.7	-2.3	-1.5	-1.4	-0.4	-1.8	-0.7	-0.8	-1.4	-0.8
Glaucoma (self-reported)	0.9	1.1	2.3	-1.1	-1.3	-1.0	-0.9	-1.3	-1.0	-1.1	-1.2	-1.5	1.3	-1.2	-0.0	-0.7	-1.2	-0.8	-1.3	-1.0	-0.8	-0.2	-1.0	-0.8	-0.6	-1.1	-1.1	-1.1	-1.3
Illnesses of siblings: Diabetes	0.9	1.2	5.2	-0.8	-0.8	-0.6	-2.3	-1.1	0.6	-0.5	-1.0	-0.4	0.0	-0.9	0.2	-1.1	-1.0	-0.4	-0.9	-0.9	-0.7	-1.3	-1.3	-0.8	-2.1	-1.6	-0.8	-0.9	-1.6
Mood swings	0.9	1.7	8.5	0.9	1.3	1.5	-0.3	1.5	2.1	1.2	0.7	2.9	-0.3	1.1	1.0	1.4	1.3	1.9	2.2	0.8	0.2	-0.4	0.9	1.4	-0.8	1.5	0.9	0.9	0.6
Bipolar Disorder or Schizophrenia	0.8	1.9	6.3	-1.6	-1.3	-0.1	-2.3	-0.9	-1.3	-2.5	-1.2	-0.2	-1.2	-1.3	0.3	0.6	-0.9	0.9	0.8	-1.7	-2.3	-2.2	-1.1	-0.9	-2.2	-0.6	0.2	-1.4	-0.6
Fed-up feelings	0.8	1.5	13.8	0.7	1.1	1.1	-0.7	1.1	1.6	0.6	0.4	3.7	0.2	0.9	0.7	1.6	1.1	1.4	1.6	0.6	-0.0	0.6	0.8	1.7	-0.7	1.3	-0.2	0.7	-0.2
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.2	0.7	0.9	1.0	1.3	1.5	0.7	0.5	0.8	1.3	0.4	0.8	-0.6	1.3	0.9	0.8	1.1	0.6	0.3	1.1	1.0	1.2	0.9	1.1	0.1	0.6	1.0
Sitting height	0.8	5.7	29.3	-3.0	-2.9	-2.4	-1.4	-1.1	0.9	-2.5	-2.8	-0.3	5.4	-2.8	1.9	0.3	-2.4	-0.7	-0.9	-3.0	-3.7	-1.9	-2.4	-1.7	-2.5	-1.8	-1.6	-2.7	-2.3
Heart attack	0.8	1.0	3.9	-1.0	-0.9	-0.4	-2.0	-0.3	0.8	-0.2	-0.9	0.4	-0.4	-1.0	-1.9	-1.0	-1.1	-0.9	-0.9	-0.9	-0.7	-0.8	-1.2	-0.6	-1.0	-0.9	-1.4	-0.9	-0.8
Number of live births	0.8	1.1	8.9	1.0	1.3	1.4	0.2	0.7	3.0	0.5	0.9	1.0	-0.8	1.2	0.2	0.8	1.2	0.7	1.1	1.1	1.0	0.7	1.0	1.2	0.3	0.5	0.7	1.0	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	5.5	0.6	0.9	1.7	-1.5	1.1	-1.0	0.4	0.6	2.2	-0.6	0.7	0.4	2.3	1.0	0.9	1.4	0.5	-0.2	0.6	1.0	1.4	0.7	1.2	0.4	0.7	0.9
Medication: Blood pressure	0.8	1.4	8.6	1.2	1.1	1.4	0.4	1.4	2.9	-0.1	1.1	0.9	0.1	1.1	0.2	0.8	1.1	0.7	0.6	1.3	1.5	1.5	1.1	1.4	1.4	0.8	0.7	1.4	1.1
Commuting to job workplace: Car/motor vehicle	0.8	1.0	5.1	1.1	0.7	0.4	1.5	0.4	-1.8	0.3	0.9	-0.5	-0.6	0.7	-0.8	-0.5	0.5	-0.7	-0.6	1.0	1.4	1.7	0.7	0.4	2.3	0.6	0.2	0.8	0.9
Illnesses of father: Heart disease	0.8	1.1	4.4	1.2	1.4	0.8	2.0	0.8	2.1	0.1	1.0	-0.1	0.4	1.2	0.1	0.8	1.0	0.6	0.6	1.1	1.2	1.1	0.9	1.2	1.1	0.4	0.5	1.0	1.2
Breast cancer (self-reported)	0.8	0.9	4.9	0.7	0.7	0.4	2.2	-0.2	-1.2	1.1	0.8	-0.9	-1.2	1.0	-0.6	0.5	0.9	0.7	1.1	0.8	0.6	-0.4	0.9	0.1	0.5	1.2	1.5	0.8	1.0
Fractured/broken bones in last 5 years	0.8	1.0	3.7	1.0	1.1	0.9	1.0	1.3	0.0	0.9	1.0	1.2	-1.0	1.0	-0.8	0.2	0.9	1.1	0.9	0.8	0.7	-0.1	1.0	0.5	1.4	1.9	1.1	0.8	1.2
Heart disease (siblings)	0.8	0.9	2.9	-1.0	-1.1	-1.0	-1.0	-0.6	0.8	-0.2	-1.0	-0.6	0.7	-1.1	-0.9	-0.9	-1.1	-1.7	-1.4	-1.0	-0.9	0.5	-0.9	-0.9	0.3	-0.6	-1.7	-1.1	-0.9
Schizophrenia vs Biploar Disorder	0.7	0.9	10.1	-0.1	0.2	0.3	-0.6	0.6	3.2	-1.0	-0.3	1.0	1.8	0.3	1.3	0.5	0.4	1.3	0.8	0.1	-0.1	-0.4	-0.0	0.7	-1.3	-0.1	0.4	0.2	-0.3
Blood Eosinophil Count	0.7	5.2	24.5	1.9	1.7	2.9	-4.6	1.6	2.4	2.3	1.9	1.0	-5.0	1.7	-0.9	-0.0	1.4	0.8	-0.4	2.3	3.2	3.5	1.8	2.2	2.7	1.1	-0.4	2.0	0.9
Heel T-Score	0.7	5.3	16.1	2.7	2.6	2.4	1.1	1.6	3.4	2.7	2.6	2.4	-0.8	2.6	-0.3	1.3	2.1	0.7	0.4	2.8	3.3	4.0	2.0	3.2	2.9	1.3	-0.1	2.6	1.7
Tanning	0.7	9.1	55.0	-2.9	-2.9	-3.0	-2.3	-3.4	-7.4	-2.1	-2.7	-2.1	-1.6	-2.9	-2.7	-3.5	-3.1	-3.1	-3.4	-2.6	-1.9	-1.4	-2.9	-2.9	-1.4	-2.3	-3.1	-2.8	-2.8
Sensitivity / hurt feelings	0.7	1.2	3.7	-1.3	-0.9	-1.0	-1.9	-0.8	0.1	-1.1	-1.4	0.9	0.3	-1.1	-1.0	-0.2	-1.0	-0.5	-0.1	-1.3	-1.5	-1.4	-1.3	-0.6	-1.9	-1.0	-1.2	-1.2	-0.9
Number of incorrect matches in round	0.7	1.1	3.5	0.8	1.2	0.7	0.7	1.2	0.9	-0.1	1.0	1.7	0.2	1.2	-0.2	1.3	1.3	1.1	1.9	0.9	0.5	-0.5	1.0	0.9	-0.1	1.2	1.6	1.1	1.4
Hair/balding pattern: Pattern 2	0.7	0.9	3.2	1.0	1.2	0.5	1.8	1.3	0.4	0.8	1.0	0.9	-1.0	1.0	-0.6	0.1	1.0	0.4	0.9	1.0	1.1	0.2	0.9	0.4	0.9	0.9	0.9	0.9	1.5
Trunk fat-free mass	0.7	4.2	11.6	1.4	1.7	1.8	1.6	2.4	3.4	0.8	1.6	3.0	1.8	1.8	2.1	2.4	2.2	3.0	3.1	1.5	0.7	-0.4	1.9	1.9	0.3	2.3	2.9	1.8	1.9
Alcohol intake versus 10 years previously	0.7	1.1	3.7	1.1	1.0	0.8	1.3	1.2	1.3	1.9	1.1	0.5	-1.0	0.9	-1.0	0.5	1.0	-0.2	0.8	0.9	0.9	1.2	1.4	0.5	1.4	1.1	0.5	1.0	1.3
Trunk predicted mass	0.7	4.2	11.2	1.4	1.8	1.8	1.6	2.3	3.4	0.8	1.6	3.0	1.8	1.8	2.1	2.4	2.2	3.0	3.1	1.5	0.7	-0.4	1.9	1.9	0.2	2.3	2.9	1.8	1.9
Medication for pain relief, constipation, heartburn	0.7	1.2	7.7	-0.2	-0.8	-1.1	0.1	-1.4	0.1	0.5	-0.2	-2.8	0.2	-0.6	-0.6	-1.5	-0.7	-2.0	-1.9	-0.2	0.5	1.2	-0.3	-1.1	0.9	-1.4	-1.0	-0.5	-0.4
Comparative height size at age 10	0.7	3.9	8.9	1.6	1.5	1.4	2.1	2.0	2.5	1.6	1.8	1.4	3.0	1.7	2.3	2.4	2.0	2.5	1.7	1.7	1.3	1.7	2.0	2.2	2.0	2.0	2.1	1.8	1.7
Osteoarthritis (self-reported)	0.7	0.9	2.0	-0.8	-1.0	-1.0	-0.9	-1.0	-1.3	-0.8	-0.9	-0.7	1.1	-0.9	0.7	-1.4	-1.0	-1.0	-1.2	-0.8	-0.5	-0.6	-1.0	-1.2	-0.8	-0.8	-0.9	-0.9	-1.4
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.1	0.7	1.0	0.9	0.0	0.8	1.3	-0.3	0.7	1.4	-1.0	1.0	-0.4	1.0	1.1	0.9	1.2	0.8	0.6	0.6	0.9	1.1	0.5	0.8	0.8	0.9	1.2
Commuting to job workplace: Public transport	0.7	0.9	4.9	0.6	0.6	0.7	-0.0	0.6	2.2	0.6	0.7	0.4	1.3	0.7	1.9	1.6	0.7	0.7	0.3	0.8	0.7	1.3	0.8	1.2	0.5	0.1	0.2	0.8	0.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	3.8	0.3	0.6	0.4	1.6	1.0	0.2	0.3	0.6	1.9	-0.0	0.7	0.1	1.5	0.8	1.0	1.7	0.5	-0.1	0.0	0.7	1.0	0.5	1.6	0.9	0.7	1.4
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	3.5	0.9	1.0	1.2	0.0	1.1	0.5	0.3	0.8	1.9	-0.6	0.9	0.5	1.0	0.9	0.9	0.6	0.9	0.7	1.0	0.8	1.3	0.7	1.3	0.1	0.9	0.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	4.0	-1.0	-0.9	-0.4	-1.8	-0.3	0.6	-0.1	-0.9	0.4	-0.4	-1.0	-2.0	-1.0	-1.1	-1.1	-1.0	-0.9	-0.6	-0.6	-1.2	-0.6	-0.8	-0.9	-1.5	-0.9	-0.8
Rheumatoid Arthritis	0.6	0.8	3.4	-1.3	-1.3	-1.1	0.2	-1.1	0.6	-1.9	-1.0	-0.8	0.4	-1.1	0.4	0.6	-0.7	-0.5	-0.1	-1.1	-1.4	-0.2	-0.8	-0.6	-0.7	-0.5	-0.8	-1.0	-0.4
Schizophrenia (2014)	0.6	1.3	6.6	-1.1	-0.7	0.1	-1.5	-0.1	-0.3	-2.6	-0.7	0.5	0.2	-0.6	1.6	0.9	-0.3	1.5	1.5	-1.1	-1.8	-2.0	-0.6	-0.3	-2.2	-0.0	0.9	-0.7	-0.3
Trunk fat percentage	0.6	2.3	8.0	1.1	1.1	0.4	2.6	0.2	1.8	1.7	1.2	0.4	-2.5	1.1	-2.8	-0.7	0.8	-1.0	-0.6	1.3	1.9	2.4	1.3	0.6	2.8	1.7	-0.8	1.1	0.7
Townsend deprivation index at recruitment	0.6	0.8	5.7	0.7	0.9	1.1	-0.0	1.4	0.8	0.8	0.5	2.4	-0.5	0.7	-0.6	0.9	0.7	1.0	1.3	0.4	-0.1	-0.5	0.6	0.7	-0.0	1.8	0.6	0.5	0.3
Trunk fat mass	0.6	2.5	7.5	1.4	1.4	0.8	2.7	0.8	2.4	1.6	1.4	1.1	-1.9	1.4	-2.1	-0.1	1.2	-0.2	0.2	1.6	1.9	2.1	1.7	1.0	2.7	2.1	-0.0	1.4	1.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.9	0.6	0.8	1.2	-0.3	0.8	0.0	0.3	0.7	1.0	-1.3	0.8	-0.1	0.8	0.9	0.6	1.2	0.6	0.2	0.1	1.0	0.4	1.1	1.7	1.2	0.7	1.2
Hip circumference	0.6	2.4	15.3	1.3	1.4	1.0	2.4	1.2	3.9	1.6	1.4	1.2	-0.5	1.4	-1.2	0.4	1.4	0.4	0.8	1.4	1.5	1.3	1.6	0.9	2.2	2.1	0.9	1.4	1.4
Headache pain in last month	0.6	1.0	4.0	0.2	0.6	1.3	-1.4	0.9	2.0	-0.7	-0.2	2.0	-0.4	0.4	0.1	1.5	0.6	1.9	1.5	0.1	-0.6	-0.5	0.4	1.2	-0.6	0.9	0.5	0.2	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	4.3	-0.4	-0.2	0.6	-1.9	0.5	-0.5	-0.7	-0.3	1.6	0.7	-0.2	2.1	1.7	0.1	0.8	0.9	-0.4	-1.2	-0.2	-0.1	0.6	-0.6	0.6	0.1	-0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.6	0.7	2.0	1.0	1.0	0.8	0.5	0.7	0.4	1.4	1.0	0.5	-0.4	1.0	0.8	0.7	1.0	1.2	0.9	0.9	0.9	0.2	1.1	0.9	0.2	0.8	1.1	0.9	0.4
Medication: Atorvastatin	0.6	0.8	3.3	0.6	0.9	1.0	-0.5	0.3	1.8	-0.3	0.5	1.7	-1.2	0.7	-1.7	-0.2	0.6	0.6	0.6	0.7	0.7	-0.8	0.6	0.3	0.4	1.4	0.7	0.7	0.5
Basal metabolic rate	0.6	3.6	12.3	1.5	1.8	1.6	2.3	2.2	3.5	1.4	1.6	2.8	0.6	1.8	0.6	1.8	2.0	2.2	2.4	1.6	1.1	0.3	1.9	1.7	1.1	2.6	2.1	1.8	1.8
Number of operations (self-reported)	0.6	0.9	10.4	-0.7	-0.2	-0.2	0.4	0.8	-3.2	-1.4	-0.4	1.7	-0.1	-0.2	-0.1	1.3	0.1	0.8	0.9	-0.3	-0.9	-0.1	0.1	0.6	-0.0	1.1	-0.1	-0.1	0.0
Ever had prostate specific antigen (PSA) test	0.6	0.6	2.8	-0.7	-0.8	-0.5	-1.2	-1.1	-0.6	-1.7	-0.5	-1.5	1.2	-0.7	1.2	-0.1	-0.4	-0.9	-0.4	-0.5	-0.5	0.0	-0.4	-0.7	0.1	-0.9	0.1	-0.5	0.2
Myopia	0.6	0.9	2.6	-0.6	-0.8	-0.8	-1.6	-0.8	-0.2	0.5	-0.8	-0.5	0.2	-0.9	0.8	-1.1	-1.1	-1.1	-1.6	-0.7	-0.3	0.0	-1.2	-0.8	-0.6	-1.4	-1.2	-0.8	-1.3
Schizophrenia (2018)	0.5	1.1	4.0	-1.0	-0.7	0.3	-2.0	-0.4	0.7	-1.9	-0.7	0.1	-0.3	-0.7	0.9	0.8	-0.4	1.1	1.2	-1.1	-1.8	-1.9	-0.7	-0.4	-1.9	-0.3	0.8	-0.8	-0.1
Coronary Artery Disease (CAD)	0.5	0.6	1.8	-0.8	-0.6	-1.0	-0.9	-0.1	0.2	-0.1	-0.8	0.0	-0.1	-0.7	-0.7	-1.3	-0.6	-0.7	-0.5	-0.9	-0.9	-1.2	-0.9	-1.1	-0.6	-0.6	-0.5	-1.0	-0.6
Lupus	0.5	0.7	5.1	0.6	0.5	0.7	-0.3	0.7	2.2	1.0	0.5	0.3	0.1	0.5	-1.0	1.3	0.5	-0.3	0.1	0.6	0.5	1.4	0.6	0.9	1.3	0.2	-0.6	0.5	0.8
Ulcerative Colitis	0.5	0.7	2.7	-0.6	-0.7	-0.7	0.1	-0.8	-1.2	-1.0	-0.9	-1.3	1.3	-0.7	0.8	0.0	-0.7	-0.8	-0.1	-0.7	-0.8	-0.4	-0.9	-0.6	-1.6	-1.6	-0.6	-0.6	-0.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.3	-1.1	-1.1	-1.0	-0.2	-0.5	-0.9	-0.7	-0.9	0.2	-0.3	-1.1	-0.3	-0.3	-0.9	-0.7	-0.7	-1.0	-1.1	-0.0	-0.6	-0.8	-0.0	-0.0	-1.0	-1.0	-1.0
Chronic bronchitis/emphysema (father)	0.5	0.6	3.1	-0.9	-0.4	-0.4	-1.0	-0.2	-0.2	-1.8	-0.6	0.5	0.4	-0.3	0.5	0.2	0.2	0.7	1.2	-0.4	-0.9	-1.5	0.0	-0.5	-0.8	0.6	1.1	-0.2	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	7.0	0.8	1.0	0.8	1.4	1.0	2.6	0.7	1.0	0.8	0.2	1.0	-0.4	1.3	1.0	0.4	1.1	0.9	0.6	1.1	0.9	1.1	1.5	1.2	0.7	1.0	1.8
Medication: Simvastatin	0.5	0.7	3.5	-0.2	-0.5	-0.2	-0.4	-0.5	1.0	0.6	-0.2	-0.8	0.7	-0.4	-1.0	-0.7	-0.8	-1.4	-1.5	-0.2	0.3	1.6	-0.7	-0.0	0.3	-1.0	-1.9	-0.3	-0.9
Forced vital capacity (FVC), Best measure	0.5	1.6	11.7	-0.7	-0.3	0.3	-0.9	0.8	3.4	-0.9	-0.8	1.9	3.0	-0.5	0.6	1.8	-0.2	1.3	1.3	-0.9	-1.6	-0.7	-0.3	0.8	-1.6	0.0	-0.2	-0.5	-0.5
Neck or shoulder pain in last month	0.5	0.7	3.8	-0.1	0.4	0.1	0.7	0.7	-0.1	-1.1	0.0	1.3	0.7	0.5	0.7	1.4	0.8	1.4	2.0	0.1	-0.6	-0.6	0.6	0.7	-0.5	0.9	1.2	0.4	0.9
Medication: Ibuprofen	0.5	0.6	2.2	-0.8	-0.6	-0.4	-1.2	-0.3	-1.2	-1.3	-0.8	0.1	0.9	-0.5	0.5	0.3	-0.3	0.4	0.7	-0.7	-1.1	-1.5	-0.7	-0.4	-1.3	-0.3	0.5	-0.5	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	3.8	0.6	0.8	0.9	1.0	0.8	0.9	-0.0	0.6	0.4	-1.9	0.6	-0.1	0.9	0.6	0.5	0.9	0.4	0.1	0.4	0.5	0.6	0.4	0.8	0.3	0.4	0.6
Whole body fat-free mass	0.5	3.1	10.6	1.2	1.6	1.4	1.9	2.1	3.3	1.0	1.4	2.7	1.1	1.6	1.0	1.9	1.9	2.3	2.5	1.4	0.7	-0.1	1.6	1.6	0.6	2.3	2.2	1.6	1.6
Whole body water mass	0.5	3.0	10.4	1.1	1.5	1.4	1.8	2.0	3.2	0.9	1.3	2.8	1.1	1.5	1.0	1.8	1.8	2.3	2.5	1.3	0.6	-0.2	1.6	1.5	0.5	2.3	2.2	1.5	1.6
High cholesterol (Self-reported)	0.5	0.9	6.9	0.9	0.6	1.3	-0.6	0.4	2.6	1.5	0.6	0.3	-1.0	0.5	-1.5	0.0	0.1	-0.6	-0.6	0.6	0.9	1.4	0.1	0.7	0.8	0.1	-1.1	0.5	-0.0
Medication: Paracetamol	0.5	0.7	3.1	-0.9	-0.4	0.1	-0.5	0.2	-0.8	-1.8	-0.6	1.3	1.0	-0.3	0.8	1.2	-0.2	1.2	1.1	-0.7	-1.4	-1.1	-0.5	0.3	-1.2	0.3	0.1	-0.5	-0.3
Basal cell carcinoma (self-reported)	0.5	0.6	2.0	0.9	1.0	0.5	0.9	0.5	1.4	0.6	0.9	0.1	0.4	0.9	0.3	0.1	1.0	0.7	0.7	1.1	1.2	-0.2	0.8	0.5	0.0	0.4	1.2	0.9	0.7
Alzheimer’s Disease (in mother)	0.4	0.5	1.1	0.5	0.6	0.2	1.0	0.4	0.4	0.0	0.8	0.5	0.1	0.7	-0.3	0.9	0.8	0.5	0.7	0.8	0.7	0.8	0.9	0.8	1.0	0.9	0.6	0.8	0.9
Ovarian Cancer	0.4	0.5	2.5	0.7	0.5	0.9	-1.6	0.7	1.1	0.6	0.6	0.5	0.1	0.5	1.5	-0.3	0.5	0.7	0.3	0.5	0.6	-0.6	0.1	0.2	-0.8	-0.6	1.0	0.4	0.0
Average weekly spirits intake	0.4	0.5	2.1	0.2	0.5	0.1	0.5	0.4	1.1	-0.5	0.3	1.5	0.4	0.5	1.0	0.4	0.6	1.2	1.2	0.4	0.1	-0.8	0.4	0.5	-0.6	0.7	1.2	0.5	0.5
Ever used hormone-replacement therapy (HRT)	0.4	0.5	3.6	-0.3	0.1	0.3	-0.4	0.5	-1.2	-0.7	-0.3	1.9	-0.3	0.0	0.3	1.2	0.1	0.9	0.9	-0.3	-0.9	-0.5	-0.1	0.5	-0.7	1.0	0.0	-0.2	-0.3
Medication: Co-codamol	0.4	0.4	1.0	0.7	0.7	1.0	0.4	0.7	-0.9	0.8	0.6	0.7	-0.7	0.7	-0.4	0.1	0.5	0.3	0.2	0.6	0.8	0.8	0.8	0.6	1.0	0.9	0.0	0.6	0.3
Forced vital capacity (FVC)	0.4	1.6	11.5	-0.7	-0.4	0.1	-0.8	0.7	2.6	-0.7	-0.9	1.8	3.4	-0.6	1.6	1.9	-0.3	1.4	0.9	-0.9	-1.5	-0.2	-0.3	0.9	-1.6	-0.2	-0.5	-0.5	-0.8
Neuroticism score	0.4	0.8	8.1	0.0	0.4	0.5	-1.1	0.6	1.1	-0.2	-0.3	2.9	0.4	0.3	1.2	1.3	0.4	1.0	1.2	-0.0	-0.6	-0.0	0.1	1.1	-1.1	0.6	-0.3	0.1	-0.4
Medication: Cholesterol lowering	0.4	0.6	3.1	-0.6	-0.6	-0.5	-1.0	-0.7	0.7	-0.7	-0.7	0.1	0.4	-0.7	-1.8	-0.8	-0.9	-0.9	-0.9	-0.6	-0.3	-0.1	-1.0	-0.4	-0.4	-0.6	-1.3	-0.6	-0.7
Illnesses of mother	0.4	0.5	3.2	-0.6	-0.1	-0.2	-0.2	0.0	-1.8	-0.8	-0.6	0.1	-0.6	-0.3	-0.9	0.3	-0.1	0.1	1.0	-0.7	-1.2	-1.2	-0.2	-0.4	-1.1	-0.1	0.0	-0.6	0.1
Peak expiratory flow (PEF)	0.4	1.0	2.9	0.9	0.9	1.5	-0.2	1.3	1.7	1.2	0.8	0.6	1.3	0.8	0.4	1.2	1.0	1.1	1.1	0.7	0.5	1.0	1.1	1.2	0.7	0.9	0.7	0.8	0.8
Medication: Paracetamol	0.4	0.7	2.7	-0.5	-0.0	0.6	-0.1	0.6	-0.5	-1.3	-0.3	1.4	-0.1	0.0	0.5	1.1	0.2	1.6	1.5	-0.4	-1.1	-1.4	-0.2	0.4	-1.1	0.6	0.7	-0.1	0.2
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	6.8	-0.8	-0.8	-1.0	0.2	-1.0	-2.6	0.2	-0.6	-1.1	-0.1	-0.7	0.1	-0.5	-0.6	-0.4	-0.3	-0.8	-0.8	-0.5	-0.5	-0.9	-0.6	-0.6	-0.3	-0.8	-0.4
Health satisfaction	0.4	0.6	1.7	0.6	0.8	1.2	0.1	0.6	1.3	-0.3	0.7	0.6	-0.5	0.8	0.2	0.9	0.9	0.4	0.8	0.8	0.7	0.7	0.9	0.8	0.7	0.9	0.5	0.8	0.8
Friendships satisfaction	0.4	0.5	6.6	0.4	0.4	0.6	-0.2	0.0	2.6	-0.2	0.2	-0.0	-0.5	0.4	1.4	0.2	0.4	0.7	0.7	0.2	0.1	-0.8	0.3	-0.1	-0.7	0.2	0.9	0.2	0.2
Wears glasses or contact lenses	0.4	0.5	2.6	0.4	0.3	0.5	0.1	0.1	1.6	0.4	0.6	0.4	0.1	0.6	0.8	0.7	0.7	0.6	-0.0	0.8	0.9	1.5	0.9	0.9	1.0	0.5	0.0	0.7	0.0
Financial situation satisfaction	0.4	0.4	3.5	-0.5	-0.3	-0.4	-0.4	-0.5	-1.9	-1.9	-0.4	-0.1	-0.7	-0.2	-0.2	-0.4	-0.1	-0.4	0.3	-0.3	-0.3	-1.0	-0.0	-0.7	-0.5	-0.1	0.4	-0.2	0.4
Alcohol drinker status: Previous	0.4	0.5	3.8	-0.4	-0.5	-0.1	-1.9	-0.5	0.5	-0.1	-0.7	0.4	0.6	-0.6	-0.1	-0.7	-0.6	-0.1	-1.0	-0.5	-0.5	-0.8	-0.7	-0.5	-0.6	-0.3	-0.6	-0.6	-1.4
Neuroticism (Nagel 2018)	0.3	0.6	6.3	-0.3	0.0	-0.1	-1.3	0.4	0.1	-0.3	-0.6	2.5	0.4	-0.3	1.0	0.6	-0.1	0.1	0.4	-0.5	-0.9	-0.1	-0.4	0.4	-1.2	0.1	-0.9	-0.4	-0.9
Ulcerative Colitis (UC)	0.3	0.6	4.0	0.3	0.0	-0.1	1.6	-0.2	-0.5	0.0	0.1	-1.3	2.0	0.2	1.8	0.4	0.2	-0.4	0.2	0.2	0.2	0.8	0.1	0.2	-0.6	-1.1	-0.0	0.2	0.2
HbA1C	0.3	0.4	2.0	0.1	-0.1	0.1	1.1	0.1	0.9	0.9	0.3	0.7	1.2	-0.2	-1.4	0.4	-0.2	0.0	-0.2	-0.3	-0.4	0.5	-0.1	0.3	0.7	0.8	-0.8	-0.2	-0.2
Number of treatments/medications taken	0.3	0.6	2.2	-0.7	-0.3	0.0	-1.1	0.0	0.6	-1.5	-0.8	1.2	0.1	-0.4	-0.3	0.3	-0.4	0.5	0.5	-0.7	-1.1	-1.1	-0.7	-0.0	-1.4	0.2	-0.4	-0.6	-0.8
Average weekly fortified wine intake	0.3	0.3	1.6	0.1	0.1	-0.0	0.7	0.2	0.4	-0.2	0.2	0.7	1.3	0.3	1.2	0.8	0.4	1.1	0.4	0.3	0.1	0.3	0.3	0.7	-0.1	0.5	0.3	0.3	-0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.3	0.5	0.2	0.2	1.2	0.2	0.9	-0.1	0.6	-0.3	0.9	0.4	0.4	-0.1	0.4	0.2	-0.2	0.7	1.0	1.1	0.5	0.5	0.7	-0.1	0.2	0.6	0.4
Medication: Atenolol	0.3	0.4	1.1	-0.4	-0.5	-0.5	-0.1	-0.0	0.1	0.9	-0.4	-0.1	-0.0	-0.6	-0.5	-0.8	-0.7	-1.0	-0.8	-0.6	-0.4	-0.2	-0.8	-0.6	-0.6	-0.6	-1.0	-0.6	-0.9
Medication: Levothyroxine sodium	0.3	0.6	2.4	0.7	0.5	0.9	-0.7	-0.1	1.4	1.6	0.8	0.7	0.3	0.5	-0.5	0.5	0.6	0.3	-0.0	0.6	0.7	1.1	0.9	0.7	1.3	1.0	0.1	0.6	0.2
Had menopause	0.3	0.3	3.0	-0.4	-0.0	-0.4	0.7	-0.7	-0.8	-1.7	-0.2	0.1	-0.6	0.1	-0.3	0.7	0.2	0.3	0.8	-0.1	-0.5	-0.9	-0.0	-0.1	-0.4	0.6	0.5	0.0	0.3
Mouth/teeth dental problems	0.3	0.4	2.1	-0.4	-0.2	-0.2	-0.6	-0.6	-0.4	-0.7	-0.4	-0.4	0.1	-0.2	1.1	0.4	-0.1	0.9	0.5	-0.3	-0.6	-1.4	-0.4	-0.2	-1.4	-0.5	0.5	-0.3	-0.4
Depression (self-reported)	0.3	0.4	4.6	-0.2	0.0	0.1	-0.7	0.3	0.2	-0.7	-0.4	2.2	-0.2	-0.1	0.0	0.5	-0.2	0.3	0.2	-0.4	-0.6	-0.1	-0.4	0.5	-0.7	0.4	-0.8	-0.3	-0.7
Prospective memory result	0.3	0.3	1.7	0.2	0.3	0.1	0.5	0.1	-1.3	-0.1	0.1	1.3	0.6	0.3	1.3	0.9	0.2	0.8	0.3	0.2	-0.0	-0.0	0.0	0.6	-0.3	0.7	0.1	0.2	-0.5
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.0	-0.0	0.4	0.3	-0.0	1.2	-1.0	-0.1	0.0	1.1	-1.4	0.2	-0.5	0.4	0.3	-0.4	1.2	-0.0	-0.3	-0.5	0.2	-0.1	-0.2	0.6	0.2	0.2	1.1
Birth weight	0.3	0.6	5.4	-1.0	-1.1	-0.4	-0.8	-1.0	-2.3	-0.2	-0.5	0.0	0.6	-0.8	0.9	0.6	-0.4	0.1	-0.5	-0.6	-0.7	0.8	-0.1	0.1	-0.1	-0.1	-0.9	-0.6	-1.1
Wheeze or whistling in the chest in last year	0.3	0.5	1.1	-1.0	-0.8	-0.9	-0.9	-0.7	-0.8	-0.6	-0.9	-0.4	-0.5	-0.8	-0.6	-0.4	-0.6	-0.7	-0.2	-0.9	-1.1	-0.9	-0.7	-0.7	-0.6	-0.5	-0.5	-0.9	-0.4
Shortness of breath walking on level ground	0.3	0.3	1.1	0.3	0.4	0.2	0.7	0.4	0.7	-0.5	0.4	0.6	-0.6	0.5	0.7	0.6	0.6	0.6	0.8	0.5	0.3	-0.8	0.6	0.2	-0.0	0.7	1.1	0.5	0.5
Emphysema/chronic bronchitis	0.3	0.3	1.4	0.2	0.4	0.4	-1.2	0.3	-0.6	0.1	0.1	1.0	-0.7	0.3	0.4	-0.1	0.5	1.1	0.7	0.3	0.1	-0.9	0.4	0.3	-0.6	0.3	0.9	0.2	-0.0
Heart disease (mother)	0.3	0.4	2.1	0.2	-0.2	-0.3	-0.0	-0.2	-0.1	0.7	0.1	-0.9	1.4	-0.2	0.5	-0.6	-0.3	-0.7	-1.1	0.0	0.4	1.4	-0.2	0.1	1.0	-0.7	-0.8	-0.0	-0.1
Pulse rate, automated reading	0.3	1.1	4.2	-0.7	-0.8	-0.5	-1.2	-0.9	0.6	-1.1	-1.0	-0.3	-2.0	-0.9	-1.5	-1.6	-1.1	-0.6	-1.1	-0.9	-0.6	-0.8	-1.0	-0.9	-0.8	-0.7	-1.2	-1.0	-1.4
Alcohol intake frequency.	0.3	0.8	6.8	0.2	0.3	-0.0	0.8	-0.4	0.6	1.1	0.2	-0.2	-2.4	0.2	-2.6	-0.9	0.2	-0.9	0.1	0.2	0.2	-0.7	0.5	-0.8	1.0	1.0	0.4	0.1	0.7
Leg pain on walking	0.3	0.4	5.9	0.5	0.6	0.2	0.6	0.6	-1.0	0.3	0.4	0.1	-2.4	0.5	-0.4	-0.5	0.3	-0.0	0.2	0.4	0.5	-0.7	0.3	-0.2	0.3	0.5	0.6	0.4	0.5
Number of self-reported non-cancer illnesses	0.3	0.6	4.2	0.3	0.4	0.3	0.7	0.8	2.0	-0.5	0.1	1.4	0.3	0.3	-0.5	1.4	0.2	0.2	0.3	0.2	-0.1	1.2	0.3	1.0	0.9	1.1	-0.7	0.3	-0.1
Eye problems/disorders: Glaucoma	0.3	0.3	2.6	-0.3	-0.5	-0.6	0.3	-0.7	-0.9	-0.2	-0.4	-1.6	0.3	-0.4	-0.0	-0.5	-0.5	-0.4	-1.0	-0.2	0.0	0.4	-0.3	-0.2	0.1	-0.8	-0.6	-0.4	-0.8
Bipolar Disorder (2011)	0.2	0.2	2.3	-0.4	-0.4	-0.6	0.1	-0.6	-1.5	-0.3	-0.4	-0.7	-0.4	-0.3	0.3	-0.2	-0.3	0.0	-0.4	-0.3	-0.2	0.3	-0.3	-0.1	-0.4	-0.5	-0.5	-0.4	-0.6
Neuroticism (2016)	0.2	0.2	1.4	-0.2	-0.1	-0.2	-0.4	0.3	-0.0	-0.5	-0.2	0.5	-1.1	-0.3	-0.1	-0.2	-0.3	0.3	0.4	-0.5	-0.6	-1.2	-0.3	-0.3	-1.0	-0.1	0.1	-0.2	0.1
Type 2 Diabetes (T2D) (2012)	0.2	0.3	2.0	-0.0	-0.2	0.1	0.8	-0.0	1.4	0.3	-0.2	-0.3	-0.5	-0.2	-0.7	-0.4	-0.3	-0.3	-0.6	-0.4	-0.1	0.8	-0.1	-0.2	0.5	-0.1	-0.7	-0.4	-0.6
Neuroticism	0.2	0.5	4.6	-0.2	-0.1	-0.1	-1.1	0.4	-0.3	-0.1	-0.5	2.1	0.3	-0.2	1.5	0.6	-0.0	0.4	0.4	-0.4	-0.8	0.1	-0.1	0.4	-0.9	0.4	-0.7	-0.4	-1.2
Angina	0.2	0.2	1.6	-0.1	-0.1	-0.2	-0.2	0.1	0.1	0.5	-0.1	0.2	0.6	-0.2	-1.3	-1.0	-0.3	-0.4	-0.4	-0.2	-0.1	-0.8	-0.4	-0.6	0.0	-0.2	0.0	-0.3	0.2
Diabetes (father)	0.2	0.3	1.6	0.4	0.1	0.2	-0.2	-0.1	0.5	1.2	0.2	-0.5	0.3	0.1	-0.5	-0.6	-0.1	-0.6	-1.0	0.3	0.7	1.3	0.0	0.2	0.8	-0.5	-0.8	0.1	-0.2
Leg fat-free mass (left)	0.2	1.3	8.1	0.6	0.8	0.6	2.0	1.3	2.8	0.9	0.7	2.0	0.8	0.8	-0.1	0.9	0.9	1.0	1.2	0.7	0.4	0.3	0.9	0.8	0.8	1.7	0.7	0.8	0.8
Leg predicted mass (left)	0.2	1.3	8.1	0.6	0.9	0.6	2.1	1.3	2.8	0.9	0.8	2.0	0.8	0.9	-0.0	0.9	1.0	1.0	1.2	0.7	0.4	0.3	0.9	0.9	0.8	1.7	0.7	0.8	0.8
Medication: Ramipril	0.2	0.2	0.9	0.0	0.1	0.3	-0.9	0.5	0.7	0.5	0.2	0.6	-0.1	0.1	-0.3	-0.1	0.2	-0.1	0.7	0.1	-0.0	-0.9	0.1	-0.4	-0.7	-0.1	0.6	0.2	0.6
Worrier / anxious feelings	0.2	0.4	3.4	-0.3	-0.3	0.3	-1.2	0.0	-1.8	0.1	-0.2	0.5	0.4	-0.3	0.5	1.2	-0.1	0.1	0.0	-0.3	-0.5	0.8	-0.2	0.8	-0.1	-0.2	-0.8	-0.2	-0.3
Happiness	0.2	0.2	1.1	-0.4	-0.3	-0.0	-1.0	-0.6	0.5	-1.0	-0.4	0.2	-0.1	-0.3	0.2	-0.2	-0.2	-0.5	0.0	-0.4	-0.5	-0.1	-0.2	-0.5	-0.1	0.1	-0.4	-0.4	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	2.2	-0.3	-0.4	-0.0	0.1	-0.1	0.1	-0.4	-0.4	0.9	1.5	-0.3	0.9	0.1	-0.2	0.5	-0.1	-0.3	-0.4	0.9	-0.2	0.4	-0.1	0.1	-0.6	-0.3	-0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.1	-0.1	-0.5	0.3	-0.6	-0.3	0.3	0.7	-0.1	-0.5	0.6	-0.5	-0.2	-0.7	-0.8	-1.1	-1.1	-0.4	-0.1	-0.1	-0.8	-0.6	-0.1	-0.8	-0.7	-0.5	-0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	1.2	0.2	-0.1	0.4	-1.0	-0.8	0.6	1.1	0.2	0.6	1.0	0.0	-0.5	0.5	0.1	0.1	-0.4	0.2	0.2	1.0	0.4	0.5	0.9	0.5	-0.4	0.1	-0.4
Worry too long after embarrassment	0.2	0.3	2.1	0.4	0.5	0.3	-0.5	0.2	1.5	0.8	0.1	0.9	1.1	0.4	0.8	0.4	0.1	0.2	-0.2	0.3	0.4	0.6	-0.2	0.8	-0.2	-0.2	-0.6	0.3	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.9	0.3	0.3	0.5	-1.4	-0.1	0.7	0.1	0.3	0.1	0.1	0.3	0.4	0.0	0.3	0.3	0.2	0.4	0.4	-0.7	0.2	-0.1	0.2	0.3	1.1	0.4	0.6
Mouth/teeth dental problems: Loose teeth	0.2	0.3	2.5	-0.1	-0.0	0.3	-0.4	0.3	0.6	-0.1	-0.1	1.6	-0.3	0.0	-0.3	0.3	0.2	-0.1	0.1	0.0	-0.1	1.3	0.2	0.6	0.5	0.7	-0.8	0.0	-0.1
Medication: Omeprazole	0.2	0.2	1.5	0.4	0.5	0.5	-0.2	0.6	0.6	-0.2	0.2	1.2	-0.3	0.4	0.5	0.6	0.3	0.2	0.1	0.4	0.2	0.5	0.2	0.7	-0.1	0.3	-0.3	0.3	-0.3
Chest pain or discomfort	0.2	0.3	2.3	0.0	0.3	0.1	-0.3	0.5	1.5	0.5	0.0	1.1	-0.9	0.0	-1.1	-0.4	0.1	0.1	0.2	0.0	-0.0	-0.7	0.0	-0.0	0.1	0.5	0.2	0.0	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.4	-0.2	-0.4	-0.2	0.3	-0.1	0.9	0.9	-0.1	0.2	0.3	-0.4	-0.7	-0.5	-0.5	-0.8	-0.8	-0.2	-0.0	0.8	-0.6	-0.1	0.3	-0.1	-1.2	-0.3	-0.3
Medication: Aspirin	0.2	0.3	1.6	-0.2	-0.1	-0.1	-0.5	-0.0	1.3	-0.2	-0.3	1.0	0.6	-0.2	-0.2	-0.5	-0.3	0.2	-0.4	-0.1	-0.0	-0.7	-0.5	0.0	-0.9	-0.2	-0.3	-0.2	-0.9
Supplements: Vitamin C	0.2	0.3	2.2	0.1	0.2	0.8	-1.5	0.1	0.2	0.1	0.2	-0.0	-0.8	0.1	-0.2	0.2	-0.0	0.2	0.2	-0.1	-0.3	-1.5	-0.1	-0.4	-0.1	0.2	0.7	-0.1	0.4
Ever had bowel cancer screening	0.2	0.3	1.5	0.1	-0.0	-0.2	0.4	-0.2	0.1	-0.9	0.1	0.7	0.3	0.2	-0.5	0.1	0.2	0.0	-0.5	0.4	0.5	1.1	0.3	0.5	1.2	1.1	-0.4	0.3	-0.3
Medication: Aspirin	0.2	0.2	1.2	-0.3	-0.2	-0.1	-0.6	-0.1	1.1	-0.3	-0.3	0.9	0.8	-0.2	-0.8	-0.4	-0.3	0.1	-0.3	-0.2	-0.2	-0.5	-0.5	0.0	-0.6	-0.1	-0.4	-0.3	-0.8
Ever taken oral contraceptive pill	0.2	0.2	0.5	0.2	0.2	0.7	-0.7	-0.3	0.4	-0.5	0.3	-0.3	0.2	0.3	0.4	0.5	0.4	0.1	0.5	0.4	0.3	-0.3	0.3	0.1	-0.2	-0.3	0.7	0.4	0.6
Alcohol drinker status: Never	0.2	0.3	2.3	-0.1	-0.0	-0.0	0.0	-0.2	-0.8	-0.1	0.1	0.3	-1.5	0.0	-0.0	-0.7	0.1	0.2	0.2	0.0	0.1	-1.4	0.1	-0.6	-0.4	0.2	1.0	0.0	0.2
Ever smoked	0.2	0.4	1.8	-0.7	-0.5	-0.3	-1.0	-0.0	-1.3	-0.9	-0.7	0.4	-0.8	-0.6	0.5	0.5	-0.4	0.6	0.1	-0.7	-0.9	-0.3	-0.4	0.1	-0.8	-0.6	-0.3	-0.6	-0.6
Age started oral contraceptive pill	0.2	0.2	1.1	-0.1	-0.3	-0.5	0.1	-0.7	-0.8	-0.7	-0.2	-1.0	0.3	-0.2	0.6	-0.4	-0.2	-0.1	-0.7	-0.1	0.2	0.7	-0.0	-0.0	0.5	-0.5	-0.2	-0.2	-0.3
Prostate Cancer	0.1	0.2	0.7	-0.6	-0.4	-0.3	0.1	-0.2	-0.2	-0.2	-0.3	0.1	0.7	-0.4	-0.2	0.1	-0.2	0.1	0.4	-0.5	-0.8	-0.7	-0.3	-0.4	-0.6	0.1	0.0	-0.5	0.0
Primary Biliary Cirrhosis	0.1	0.1	0.3	-0.3	-0.3	-0.1	0.0	-0.4	-0.2	-0.1	-0.1	0.1	0.2	-0.2	-0.4	0.6	0.0	0.3	0.2	-0.2	-0.5	-0.4	0.0	-0.2	0.3	0.5	0.2	-0.3	-0.1
Hypothyroidism (self reported)	0.1	0.3	1.8	-0.1	-0.4	-0.2	0.3	-1.4	0.3	1.1	0.1	-0.5	0.5	-0.2	-1.1	0.0	-0.1	-0.4	-0.6	0.0	0.1	0.8	0.3	-0.2	1.2	0.6	-0.3	-0.1	-0.2
Hair Pigment	0.1	2.6	11.6	0.3	1.2	1.2	2.2	1.5	2.4	-1.0	0.7	1.5	-1.3	1.1	-0.4	1.9	1.5	2.2	3.4	0.5	-0.5	-1.8	1.3	0.7	-0.4	1.9	2.5	0.9	2.3
Serious illness, injury or assault to yourself	0.1	0.2	0.7	-0.2	-0.1	-0.8	0.7	-0.1	-0.4	-0.6	-0.4	0.8	0.7	-0.1	-0.6	-0.3	-0.1	-0.3	-0.1	-0.1	-0.1	0.4	-0.1	0.1	0.0	-0.0	-0.5	-0.1	-0.1
Past tobacco smoking	0.1	0.3	1.3	-0.0	-0.0	-0.4	0.1	-0.8	0.3	0.7	-0.1	-0.7	-0.2	-0.1	-1.2	-1.1	-0.3	-1.0	-0.5	-0.1	0.2	-0.6	-0.4	-0.7	-0.2	-0.2	-0.3	-0.1	-0.2
Hair/balding pattern: Pattern 4	0.1	0.2	1.2	0.2	0.1	0.2	0.1	-0.1	0.3	1.0	0.2	0.0	0.5	0.1	0.1	-0.1	0.2	-0.4	-0.7	0.4	0.5	1.1	0.3	0.5	1.0	0.1	-0.4	0.2	-0.2
Birth weight of first child	0.1	0.1	0.8	-0.2	-0.2	0.2	-0.6	0.1	-0.0	-0.8	0.1	-0.1	0.6	-0.1	0.5	0.9	0.2	0.5	0.4	0.0	-0.2	-0.0	0.2	0.3	0.2	0.2	0.5	0.1	0.4
Angina (self-reported)	0.1	0.2	1.6	-0.0	-0.1	-0.1	-0.2	0.2	0.0	0.5	-0.1	0.1	0.3	-0.1	-1.3	-1.0	-0.3	-0.3	-0.3	-0.2	-0.0	-0.9	-0.4	-0.5	-0.0	-0.2	0.2	-0.2	0.2
Smoking status: Previous	0.1	0.2	1.7	-0.1	-0.3	-0.0	-0.1	0.3	-0.2	-0.8	-0.0	-0.3	1.3	-0.2	0.9	0.3	-0.1	0.1	-0.3	-0.0	0.0	0.8	-0.0	0.2	0.5	-0.4	-0.1	-0.0	0.1
Leg fat-free mass (right)	0.1	0.7	6.2	0.1	0.3	0.1	1.6	0.9	2.5	0.3	0.2	1.8	1.0	0.3	-0.2	0.5	0.5	0.8	1.0	0.2	-0.2	-0.3	0.4	0.3	0.2	1.4	0.5	0.3	0.3
Osteoporosis (self-reported)	0.1	0.1	0.6	-0.0	0.1	0.2	-0.2	0.5	-0.8	0.0	0.2	-0.1	0.3	0.1	-0.4	0.2	0.2	0.2	0.5	-0.1	-0.2	0.2	0.3	0.1	0.2	0.3	0.2	-0.0	0.4
Leg predicted mass (right)	0.1	0.7	6.3	0.0	0.3	0.0	1.6	0.9	2.5	0.3	0.1	1.7	1.0	0.3	-0.2	0.4	0.4	0.8	0.9	0.2	-0.2	-0.4	0.4	0.3	0.1	1.3	0.5	0.3	0.2
Risk taking	0.1	0.2	1.5	-0.1	-0.1	0.3	0.1	0.3	-0.0	0.2	0.1	1.2	-0.6	-0.2	-0.1	0.5	-0.1	0.5	-0.0	-0.3	-0.5	-0.1	0.2	0.0	0.7	1.1	-0.0	-0.2	-0.3