Best TWAS P=2.93e-08 · Best GWAS P=3.26e-09 conditioned to 5.59e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | GRID1 | 0.16 | 0.08 | enet | 32 | 0.06 | 2.5e-05 | -5.3 | -5.2 | 2.1e-07 | -0.12 | 0.03 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GRID1 | 0.09 | 0.04 | lasso | 9 | 0.03 | 2.1e-07 | -5.3 | -5.5 | 2.9e-08 | -0.40 | 0.07 | 0.93 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GRID1 | 0.07 | 0.03 | lasso | 4 | 0.02 | 9.7e-04 | -5.3 | -5.3 | 1.4e-07 | -0.34 | 0.03 | 0.94 | FALSE |