[Hub]/) : Traits : Leg fat mass (left) : →

chr1:752,566-3,212,946

Best TWAS P=9.69e-12 · Best GWAS P=6.96e-10 conditioned to 0.0663

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Esophagus Muscularis	RP1-283E3.4	0.46	0.14	enet	23	0.24	1.6e-14	-3.6	-6.8	9.7e-12	0.01	0.74	0.10	TRUE
11	GTEx	Esophagus Muscularis	RP3-395M20.12	0.08	0.06	enet	6	0.06	2.3e-04	4.6	-6.2	5.3e-10	0.78	0.01	0.98	TRUE
14	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-4.7	5.3	9.8e-08	-0.02	0.04	0.95	TRUE
23	GTEx	Thyroid	RP1-283E3.4	0.59	0.04	lasso	10	0.22	3.8e-17	-3.6	-6.5	6.8e-11	0.00	0.59	0.08	FALSE
9	GTEx	Esophagus Mucosa	RP1-283E3.4	0.53	0.12	enet	20	0.22	4.1e-15	-3.6	-6.5	1.0e-10	0.02	0.77	0.10	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	RP1-283E3.4	0.48	0.12	lasso	5	0.31	1.1e-17	-3.6	-6.2	4.9e-10	0.01	0.38	0.12	FALSE
7	GTEx	Cells Transformed fibroblasts	RP1-283E3.4	0.59	0.13	lasso	8	0.29	3.0e-22	2.9	-6.2	5.8e-10	0.01	0.84	0.01	FALSE
1	GTEx	Adipose Subcutaneous	RP1-283E3.4	0.65	0.14	lasso	9	0.33	5.1e-28	-3.6	-6.1	9.2e-10	0.00	0.77	0.10	FALSE
15	GTEx	Muscle Skeletal	SLC35E2B	0.35	0.06	lasso	4	0.19	3.2e-18	-3.4	6.1	1.1e-09	0.01	0.79	0.06	FALSE
2	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-3.6	-5.8	5.4e-09	-0.02	0.13	0.07	FALSE
16	GTEx	Muscle Skeletal	RP1-283E3.4	0.51	0.12	lasso	6	0.29	2.4e-28	-3.6	-5.7	9.6e-09	0.01	0.77	0.10	FALSE
4	GTEx	Artery Tibial	RP1-283E3.4	0.66	0.09	lasso	6	0.38	4.9e-31	-3.6	-5.7	1.1e-08	0.01	0.79	0.08	FALSE
13	GTEx	Lung	RP1-283E3.4	0.58	0.07	lasso	7	0.34	8.8e-27	-3.6	-5.7	1.2e-08	0.02	0.80	0.06	FALSE
3	GTEx	Artery Aorta	RP1-283E3.4	0.60	0.12	lasso	9	0.27	3.2e-15	-3.6	-5.7	1.3e-08	-0.01	0.42	0.14	FALSE
17	GTEx	Muscle Skeletal	RP11-345P4.10	0.54	0.06	lasso	7	0.29	4.7e-29	-3.4	5.7	1.4e-08	0.00	0.82	0.04	FALSE
5	GTEx	Artery Tibial	RP11-345P4.10	0.61	0.10	lasso	10	0.36	3.1e-29	-3.4	5.5	3.0e-08	0.01	0.81	0.06	FALSE
24	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	4.9	5.5	3.3e-08	-0.63	0.44	0.56	FALSE
18	GTEx	Pancreas	TNFRSF14	0.13	0.04	enet	8	0.04	1.0e-02	4.6	5.5	3.8e-08	-0.63	0.18	0.72	FALSE
12	GTEx	Heart Atrial Appendage	RP11-345P4.10	0.36	0.11	enet	15	0.16	1.1e-07	-3.4	5.4	6.1e-08	-0.01	0.08	0.05	FALSE
22	GTEx	Spleen	RP3-395M20.9	0.42	0.14	lasso	3	0.15	1.1e-04	-5.7	-5.4	6.2e-08	0.59	0.03	0.80	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-345P4.10	0.66	0.17	lasso	13	0.32	7.5e-25	-3.4	5.4	8.5e-08	0.00	0.81	0.06	FALSE
6	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-4.6	5.3	1.4e-07	-0.01	0.01	0.42	FALSE
19	GTEx	Pancreas	CALML6	0.21	0.08	lasso	4	0.06	2.2e-03	-5.1	-5.2	2.3e-07	0.00	0.02	0.96	FALSE
21	GTEx	Spleen	TMEM52	0.47	0.21	lasso	5	0.22	2.3e-06	-4.5	-5.1	2.8e-07	0.01	0.03	0.91	FALSE