Best TWAS P=7.88e-09 · Best GWAS P=5.22e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | ARL14EP | 0.33 | 0.25 | lasso | 10 | 0.26 | 3.7e-08 | 5.5 | -5.8 | 7.9e-09 | -0.96 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Esophagus Muscularis | ARL14EP | 0.18 | 0.20 | lasso | 8 | 0.19 | 9.5e-12 | 5.8 | -5.8 | 8.0e-09 | -0.95 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Pituitary | ARL14EP | 0.30 | 0.28 | lasso | 4 | 0.22 | 3.0e-06 | 5.7 | -5.7 | 9.3e-09 | -0.82 | 0.02 | 0.96 | FALSE |
| 4 | GTEx | Pancreas | ARL14EP | 0.16 | 0.08 | lasso | 6 | 0.07 | 1.0e-03 | 5.2 | -5.7 | 9.9e-09 | -0.91 | 0.01 | 0.96 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | ARL14EP | 0.15 | 0.14 | lasso | 3 | 0.11 | 1.2e-04 | 5.5 | -5.6 | 2.2e-08 | -0.94 | 0.01 | 0.98 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | ARL14EP | 0.08 | 0.07 | enet | 13 | 0.08 | 5.3e-10 | 5.8 | -5.2 | 2.2e-07 | -0.95 | 0.01 | 0.99 | FALSE |