TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
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→
chr12:107,433,672-108,852,590
Best TWAS P=1.55e-10 · Best GWAS P=7.67e-11 conditioned to 1
107.4M
107.6M
107.8M
108M
108.2M
108.4M
108.6M
108.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Whole Blood
PRDM4
0.10
0.08
lasso
5
0.05
1.8e-05
6.4
-6.4
1.6e-10
-0.99
0.01
0.99
TRUE
1
CommonMind
Brain Pre-frontal Cortex
PRDM4
0.07
0.08
lasso
2
0.07
5.0e-09
6.4
6.3
2.4e-10
0.97
0.01
0.99
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
ASCL4
0.03
0.03
blup
49
0.03
2.9e-04
6.4
6.0
1.6e-09
0.88
0.01
0.94
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
PRDM4
0.01
0.01
lasso
1
0.01
6.3e-03
5.5
-5.5
4.7e-08
-0.87
0.02
0.84
FALSE