Best TWAS P=3.66e-08 · Best GWAS P=2.85e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | PIK3C3 | 0.16 | 0.12 | enet | 13 | 0.15 | 1.2e-10 | 4.1 | -5.2 | 2.5e-07 | -0.60 | 0.96 | 0.04 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | PIK3C3 | 0.09 | 0.04 | lasso | 8 | 0.03 | 6.0e-03 | 5.9 | -5.5 | 3.7e-08 | -0.98 | 0.01 | 0.92 | TRUE |