TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
←
→
chr18:38,837,001-40,365,619
Best TWAS P=3.66e-08 · Best GWAS P=2.85e-09 conditioned to 1
38.8M
39M
39.2M
39.4M
39.6M
39.8M
40M
40.2M
40.4M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Colon Adenocarcinoma
PIK3C3
0.09
0.04
lasso
8
0.03
6.0e-03
5.9
-5.5
3.7e-08
-0.98
0.01
0.92
TRUE
1
GTEx
Nerve Tibial
PIK3C3
0.16
0.12
enet
13
0.15
1.2e-10
4.1
-5.2
2.5e-07
-0.60
0.96
0.04
FALSE