Best TWAS P=5.14e-09 · Best GWAS P=3.06e-08 conditioned to 0.193
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | SEMA6C | 0.35 | 0.22 | lasso | 2 | 0.17 | 1.1e-05 | 4.3 | 5.2 | 1.8e-07 | 0.82 | 0.15 | 0.54 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | GABPB2 | 0.12 | 0.02 | enet | 10 | 0.04 | 2.7e-03 | 4.8 | 5.3 | 1.2e-07 | 0.85 | 0.02 | 0.96 | FALSE |
| 3 | METSIM | Adipose | BNIPL | 0.05 | 0.01 | blup | 313 | 0.03 | 9.7e-05 | 3.3 | 5.5 | 3.9e-08 | 0.60 | 0.16 | 0.74 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | BNIPL | 0.03 | 0.02 | blup | 35 | 0.02 | 6.4e-03 | 4.4 | 5.8 | 5.1e-09 | 0.82 | 0.01 | 0.64 | TRUE |