Best TWAS P=2.36e-09 · Best GWAS P=4.33e-07 conditioned to 0.487
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | TSPAN2 | 0.03 | 0.01 | bslmm | 494 | 0.02 | 9.6e-07 | -5.1 | -5.2 | 1.7e-07 | 0.69 | 0 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | SIKE1 | 0.44 | 0.09 | lasso | 7 | 0.13 | 1.9e-04 | -4.4 | -6.0 | 2.4e-09 | 0.77 | 0 | 0.21 | TRUE |