[Hub]/) : Traits : Leg fat mass (left) : ← →

chr1:173,178,453-175,663,031

Best TWAS P=5.3e-10 · Best GWAS P=1.08e-08 conditioned to 0.935

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RC3H1 0.12 0.06 lasso 2 0.06 3.2e-03 5.5 -5.4 6.2e-08 -0.98 0.04 0.79 FALSE
2 GTEx Artery Tibial RC3H1 0.09 0.07 lasso 2 0.07 2.6e-06 5.5 -5.5 3.5e-08 -0.98 0.02 0.97 FALSE
3 GTEx Breast Mammary Tissue (Male) RC3H1 0.07 0.11 enet 3 0.07 9.9e-03 5.6 -5.6 1.8e-08 -1.00 0.02 0.61 FALSE
4 GTEx Breast Mammary Tissue (Female) RABGAP1L 0.19 0.00 lasso 3 0.01 2.0e-01 5.5 6.2 5.3e-10 0.92 0.06 0.42 TRUE
5 GTEx Nerve Tibial RC3H1 0.09 0.06 enet 7 0.07 7.0e-06 5.0 -5.3 9.7e-08 -0.97 0.05 0.95 FALSE
6 GTEx Ovary RC3H1 0.32 0.03 lasso 8 0.07 8.6e-03 5.5 -5.9 4.6e-09 -0.82 0.02 0.58 FALSE
7 METSIM Adipose SERPINC1 0.10 0.09 bslmm 271 0.09 1.2e-13 5.2 5.7 1.4e-08 0.95 0.04 0.96 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SERPINC1 0.11 0.06 blup 47 0.05 3.7e-06 5.2 5.1 2.7e-07 0.88 0.01 0.99 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CACYBP 0.11 0.05 lasso 2 0.04 9.6e-04 5.2 5.2 2.5e-07 0.95 0.00 0.95 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MRPS14 0.12 0.01 lasso 4 0.01 1.1e-01 5.2 5.3 1.1e-07 0.94 0.00 0.89 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors RC3H1 0.13 -0.01 blup 58 0.01 1.4e-01 5.5 5.9 4.9e-09 0.80 0.01 0.24 FALSE