Best TWAS P=9.45e-11 · Best GWAS P=1.75e-10 conditioned to 0.762
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | GGT7 | 0.06 | 0.00 | enet | 7 | 0.02 | 1.9e-02 | -5.0 | 6.3 | 2.6e-10 | -0.38 | 0.06 | 0.75 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | ITCH | 0.09 | 0.04 | enet | 28 | 0.09 | 2.5e-05 | 3.3 | -5.2 | 2.3e-07 | 0.72 | 0.27 | 0.70 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | NCOA6 | 0.11 | 0.06 | enet | 15 | 0.06 | 3.9e-03 | 4.9 | -5.2 | 1.9e-07 | 0.43 | 0.07 | 0.72 | FALSE |
| 4 | GTEx | Thyroid | MYH7B | 0.06 | 0.03 | enet | 15 | 0.06 | 3.6e-05 | 5.2 | 5.2 | 2.1e-07 | -0.36 | 0.04 | 0.95 | FALSE |
| 5 | YFS | Blood | EIF2S2 | 0.07 | 0.07 | enet | 25 | 0.06 | 4.3e-20 | -6.1 | 6.5 | 9.4e-11 | -0.90 | 0.02 | 0.98 | TRUE |