Best TWAS P=8.1e-08 · Best GWAS P=7.66e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | NBAS | 0.14 | 0.14 | bslmm | 685 | 0.16 | 2.0e-18 | -5.2 | -5.1 | 2.7e-07 | 0.94 | 0.06 | 0.94 | FALSE |
2 | GTEx | Brain Cortex | NBAS | 0.15 | 0.10 | lasso | 1 | 0.09 | 2.0e-03 | -5.2 | -5.2 | 2.2e-07 | 0.98 | 0.06 | 0.86 | FALSE |
3 | GTEx | Heart Atrial Appendage | NBAS | 0.29 | 0.11 | lasso | 5 | 0.17 | 3.1e-08 | -5.2 | 5.4 | 8.1e-08 | -0.97 | 0.06 | 0.94 | TRUE |
4 | GTEx | Nerve Tibial | NBAS | 0.11 | 0.09 | lasso | 4 | 0.07 | 2.1e-05 | -5.3 | -5.2 | 1.6e-07 | 0.97 | 0.06 | 0.94 | FALSE |
5 | GTEx | Thyroid | NBAS | 0.08 | 0.05 | lasso | 3 | 0.05 | 1.9e-04 | -4.8 | -5.2 | 2.6e-07 | 0.90 | 0.07 | 0.93 | FALSE |