[Hub]/) : Traits : Leg fat mass (left) :

chr2:35,883,253-37,567,226

Best TWAS P=1.22e-09 · Best GWAS P=1.4e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FEZ2 0.16 0.24 lasso 2 0.22 1.3e-26 6.1 -6.1 1.2e-09 -1.00 0.00 1.00 TRUE
2 GTEx Adipose Subcutaneous AC007401.1 0.10 0.02 lasso 4 0.02 5.4e-03 5.6 5.9 2.9e-09 0.88 0.04 0.91 FALSE
3 GTEx Artery Tibial CRIM1 0.10 0.04 lasso 4 0.05 1.4e-04 5.6 -6.0 2.3e-09 -0.87 0.03 0.96 FALSE
4 GTEx Brain Cerebellar Hemisphere CRIM1 0.36 0.21 lasso 5 0.16 5.4e-05 5.7 5.7 1.5e-08 0.86 0.05 0.87 FALSE
5 GTEx Brain Cerebellar Hemisphere FEZ2 0.41 0.30 lasso 6 0.28 8.6e-08 5.6 5.7 1.5e-08 0.91 0.03 0.96 FALSE
6 GTEx Brain Cerebellar Hemisphere AC007401.1 0.40 0.26 lasso 4 0.22 2.3e-06 5.7 5.7 1.5e-08 0.89 0.04 0.94 FALSE
7 GTEx Brain Cerebellar Hemisphere RP11-490M8.1 0.37 0.18 lasso 4 0.15 1.2e-04 5.7 5.8 6.3e-09 0.92 0.03 0.90 FALSE
8 GTEx Brain Cerebellum FEZ2 0.44 0.26 lasso 6 0.23 2.6e-07 5.4 5.6 1.9e-08 0.85 0.08 0.91 FALSE
9 GTEx Brain Cerebellum AC007401.1 0.27 0.21 enet 5 0.20 1.5e-06 5.7 5.7 1.3e-08 0.87 0.06 0.92 FALSE
10 GTEx Spleen FEZ2 0.42 0.16 enet 25 0.17 3.9e-05 4.8 5.9 4.0e-09 0.69 0.05 0.85 FALSE
11 GTEx Whole Blood FEZ2 0.11 0.09 enet 25 0.10 8.4e-10 5.6 5.5 2.9e-08 0.82 0.05 0.95 FALSE
12 GTEx Whole Blood AC007401.1 0.06 0.06 lasso 5 0.05 4.6e-05 5.6 5.9 4.8e-09 0.91 0.06 0.92 FALSE
13 NTR Blood CRIM1 0.09 0.10 lasso 6 0.11 3.1e-32 5.0 -5.4 7.2e-08 -0.93 0.13 0.87 FALSE
14 ROSMAP Brain Pre-frontal Cortex FEZ2 0.41 0.55 lasso 5 0.58 3.1e-93 5.9 -5.7 1.2e-08 -0.95 0.03 0.97 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma FEZ2 0.01 0.01 blup 85 0.01 1.0e-03 5.6 -6.0 2.5e-09 -0.92 0.01 0.96 FALSE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FEZ2 0.06 0.05 lasso 4 0.04 3.3e-03 5.4 -5.4 6.6e-08 -0.94 0.03 0.87 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma FEZ2 0.11 0.03 blup 84 0.07 6.1e-05 6.1 -5.2 1.5e-07 -0.91 0.02 0.97 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma FEZ2 0.06 0.05 blup 87 0.08 1.4e-08 5.9 -5.9 4.6e-09 -0.93 0.02 0.98 FALSE