TWAS
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Traits
:
Leg fat mass (left)
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chr4:67,642,191-69,098,006
Best TWAS P=7.74e-09 · Best GWAS P=5.88e-09 conditioned to 2.81e-06
67.6M
67.8M
68M
68.2M
68.4M
68.6M
68.8M
69M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
CENPC
0.22
0.04
enet
17
0.10
2.8e-08
3.8
-5.8
7.7e-09
-0.22
0.58
0.30
TRUE
2
GTEx
Esophagus Mucosa
CENPC
0.13
0.03
enet
8
0.08
3.6e-06
3.8
-5.2
1.5e-07
-0.07
0.46
0.42
FALSE