[Hub]/) : Traits : Leg fat mass (left) : ← →

chr4:52,683,607-53,598,975

Best TWAS P=1.21e-08 · Best GWAS P=2.49e-08 conditioned to 0.22

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	ROSMAP	Brain Pre-frontal Cortex	SGCB	0.03	0.03	enet	9	0.03	7.0e-05	5.1	5.7	1.2e-08	0.87	0.04	0.95	TRUE
2	GTEx	Breast Mammary Tissue (Female)	DCUN1D4	0.02	0.03	lasso	1	0.02	8.2e-02	5.4	5.4	6.6e-08	0.96	0.02	0.20	FALSE
4	GTEx	Thyroid	DCUN1D4	0.03	0.05	lasso	1	0.04	2.4e-04	5.4	5.4	6.6e-08	0.96	0.03	0.93	FALSE
3	GTEx	Nerve Tibial	DCUN1D4	0.10	0.09	lasso	3	0.10	6.8e-08	4.9	5.3	1.2e-07	0.93	0.07	0.93	FALSE
1	GTEx	Breast Mammary Tissue	DCUN1D4	0.08	0.02	enet	11	0.04	2.4e-03	5.4	5.2	2.4e-07	0.89	0.04	0.90	FALSE