TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat mass (left)
:
←
→
chr5:76,597,461-78,287,579
Best TWAS P=2.7e-11 · Best GWAS P=1.82e-10 conditioned to 0.0858
76.6M
76.8M
77M
77.2M
77.4M
77.6M
77.8M
78M
78.2M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
AP3B1
0.05
0.02
blup
126
0.03
5.0e-04
5.4
-6.7
2.7e-11
0.80
0.02
0.91
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
AP3B1
0.02
0.00
blup
126
0.01
1.8e-02
-6.2
-6.4
1.3e-10
0.86
0.02
0.90
FALSE
1
YFS
Blood
AP3B1
0.25
0.22
lasso
9
0.23
2.6e-74
5.2
-5.4
5.4e-08
0.31
0.77
0.23
FALSE
3
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
AP3B1
0.16
0.06
enet
18
0.09
2.2e-05
5.5
-5.3
1.0e-07
0.53
0.04
0.56
FALSE