[Hub]/) : Traits : Leg fat mass (left) : ← →

chr7:2,032,803-3,581,391

Best TWAS P=2.74e-11 · Best GWAS P=1.37e-09 conditioned to 0.872

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-5.6	6.7	2.7e-11	-0.90	0.04	0.96	TRUE
1	CommonMind	Brain Pre-frontal Cortex	AMZ1	0.19	0.12	enet	22	0.13	5.7e-16	4.9	6.0	1.5e-09	-0.43	0.38	0.62	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-6.1	-5.9	3.9e-09	0.99	0.00	1.00	FALSE
7	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	4.1	-5.8	5.6e-09	0.71	0.01	0.66	FALSE
4	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-5.6	-5.8	7.2e-09	0.94	0.02	0.90	FALSE
6	YFS	Blood	GNA12	0.23	0.15	bslmm	570	0.25	4.5e-82	5.6	-5.5	3.1e-08	0.52	0.04	0.96	FALSE
3	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-5.6	-5.3	1.3e-07	0.94	0.02	0.98	FALSE