Best TWAS P=1.49e-17 · Best GWAS P=1.67e-27 conditioned to 1.21e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -6.3 | 7.0 | 3.2e-12 | -0.66 | 0.73 | 0.1 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.6 | 8.5 | 1.5e-17 | -0.48 | 1.00 | 0.0 | TRUE |