[Hub]/) : Traits : Leg fat mass (left) : ← →

chr1:76,862,305-79,300,939

Best TWAS P=1.18e-12 · Best GWAS P=1.32e-21 conditioned to 2.76e-13

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Colon Adenocarcinoma	GIPC2	0.04	0.01	blup	65	0.00	2.5e-01	-5.4	7.1	1.2e-12	0.28	0.07	0.06	TRUE
1	GTEx	Artery Coronary	PIGK	0.22	0.00	lasso	8	-0.01	9.0e-01	5.0	-5.5	4.2e-08	-0.10	0.08	0.06	TRUE
7	GTEx	Spleen	GIPC2	0.43	0.07	enet	19	0.22	2.9e-06	-6.2	6.7	1.7e-11	0.22	0.83	0.02	FALSE
8	METSIM	Adipose	DNAJB4	0.04	0.04	lasso	4	0.03	2.1e-05	-5.8	-6.3	2.4e-10	-0.26	0.70	0.01	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIPC2	0.02	0.02	lasso	3	0.02	1.0e-03	-6.2	6.3	3.7e-10	0.22	0.37	0.02	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	DNAJB4	0.08	0.09	lasso	2	0.09	1.3e-11	-6.1	-6.1	8.1e-10	-0.18	1.00	0.00	FALSE
4	GTEx	Nerve Tibial	DNAJB4	0.08	0.07	lasso	3	0.07	1.3e-05	-5.9	-6.1	1.0e-09	-0.14	0.82	0.01	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJB4	0.04	0.04	lasso	2	0.04	1.2e-05	6.1	-6.1	1.1e-09	-0.45	0.00	1.00	FALSE
6	GTEx	Skin Sun Exposed Lower leg	DNAJB4	0.07	0.05	lasso	5	0.05	6.5e-05	-5.9	-6.0	1.9e-09	-0.11	0.60	0.01	FALSE
3	GTEx	Lung	GIPC2	0.15	0.09	enet	17	0.12	2.5e-09	-5.0	5.9	3.1e-09	0.19	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DNAJB4	0.05	0.03	lasso	3	0.02	3.3e-03	-5.7	-5.7	1.5e-08	-0.20	0.07	0.78	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	DNAJB4	0.08	0.07	lasso	1	0.06	9.3e-08	-5.7	-5.7	1.6e-08	-0.19	0.03	0.97	FALSE
16	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DNAJB4	0.24	0.14	lasso	1	0.11	1.1e-04	-5.7	-5.7	1.6e-08	-0.19	0.03	0.75	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	GIPC2	0.07	0.05	blup	64	0.06	1.5e-06	-4.5	5.6	1.7e-08	0.28	0.67	0.02	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	NEXN	0.23	0.10	lasso	3	0.08	1.4e-03	-4.9	-5.5	3.3e-08	-0.13	0.21	0.04	FALSE
5	GTEx	Pancreas	GIPC2	0.41	0.13	enet	29	0.14	1.1e-06	-5.7	5.4	6.1e-08	0.31	0.65	0.10	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	GIPC2	0.02	0.02	lasso	2	0.02	8.3e-05	-5.2	5.3	1.3e-07	0.24	0.56	0.02	FALSE