[Hub]/) : Traits : Leg fat mass (left) : ← →

chr9:14,857,740-16,758,776

Best TWAS P=1.37e-23 · Best GWAS P=2.76e-19 conditioned to 0.547

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cerebellar Hemisphere	CCDC171	0.46	0.19	lasso	7	0.23	1.3e-06	-8.8	-10.0	1.4e-23	0.87	0.14	0.84	TRUE
5	GTEx	Brain Cerebellum	CCDC171	0.46	0.22	lasso	7	0.15	3.4e-05	-8.7	-9.2	5.0e-20	0.95	0.06	0.94	FALSE
3	GTEx	Brain Caudate basal ganglia	CCDC171	0.30	0.18	lasso	4	0.23	2.4e-07	8.1	-8.8	1.7e-18	0.92	0.08	0.92	FALSE
11	GTEx	Nerve Tibial	CCDC171	0.25	0.16	lasso	6	0.14	2.1e-10	-8.6	-8.6	8.3e-18	0.95	0.13	0.87	FALSE
13	GTEx	Pituitary	CCDC171	0.28	0.16	enet	29	0.12	5.2e-04	7.9	-8.5	2.5e-17	0.87	0.23	0.69	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	CCDC171	0.14	0.11	enet	21	0.11	8.3e-14	8.2	-8.3	1.3e-16	0.80	0.77	0.23	FALSE
7	GTEx	Brain Frontal Cortex BA9	CCDC171	0.27	0.18	enet	10	0.19	8.3e-06	8.2	-8.1	4.1e-16	0.81	0.09	0.84	FALSE
6	GTEx	Brain Cortex	CCDC171	0.26	0.15	lasso	2	0.16	2.8e-05	-7.1	-8.1	5.7e-16	0.89	0.12	0.82	FALSE
16	METSIM	Adipose	CCDC171	0.03	0.00	blup	828	0.01	4.0e-02	8.2	-7.6	3.8e-14	0.77	0.20	0.58	FALSE
8	GTEx	Brain Hypothalamus	CCDC171	0.32	0.17	enet	6	0.09	4.0e-03	-8.8	-7.4	1.1e-13	0.90	0.09	0.70	FALSE
12	GTEx	Ovary	CCDC171	0.21	0.19	lasso	4	0.16	7.7e-05	7.8	7.4	1.1e-13	-0.82	0.14	0.56	FALSE
10	GTEx	Lung	CCDC171	0.13	0.03	enet	9	0.01	5.0e-02	5.4	-7.1	1.1e-12	0.65	0.39	0.38	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	C9orf93	0.06	0.05	lasso	3	0.03	5.3e-03	7.5	-6.5	6.5e-11	0.67	0.12	0.30	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CCDC171	0.14	0.09	enet	13	0.12	1.9e-10	7.8	-6.3	2.2e-10	0.61	0.96	0.04	FALSE
2	GTEx	Artery Tibial	CCDC171	0.10	0.09	enet	9	0.12	7.2e-10	4.8	-6.0	1.8e-09	0.57	0.85	0.14	FALSE
1	GTEx	Artery Aorta	CCDC171	0.18	0.05	lasso	5	0.08	2.2e-05	-4.1	-5.7	1.5e-08	0.30	0.33	0.07	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CCDC171	0.20	0.04	enet	45	0.06	4.9e-04	8.2	-5.5	3.4e-08	0.37	0.66	0.23	FALSE
9	GTEx	Breast Mammary Tissue	CCDC171	0.21	0.01	lasso	5	0.03	1.5e-02	7.5	-5.3	1.2e-07	0.52	0.35	0.23	FALSE