[Hub]/) : Traits : Leg fat-free mass (left) : →

chr1:752,566-3,191,909

Best TWAS P=2.42e-10 · Best GWAS P=1.26e-08 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 -5.1 -6.1 9.4e-10 -0.11 0.11 0.76 TRUE
2 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 -2.6 -5.4 8.1e-08 -0.27 0.14 0.16 TRUE
3 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 -5.5 6.0 2.6e-09 0.28 0.02 0.60 TRUE
4 GTEx Esophagus Gastroesophageal Junction RP11-181G12.2 0.16 0.02 enet 18 0.01 1.1e-01 5.1 5.4 7.7e-08 0.01 0.07 0.39 FALSE
5 GTEx Esophagus Muscularis RP11-181G12.2 0.23 0.14 lasso 4 0.19 1.0e-11 4.8 5.7 9.7e-09 0.00 0.13 0.87 FALSE
6 GTEx Lung AL590822.2 0.09 0.00 lasso 3 0.00 2.0e-01 5.0 5.3 9.8e-08 0.06 0.07 0.25 FALSE
7 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 -5.0 -5.5 3.2e-08 -0.23 0.07 0.76 FALSE
8 GTEx Muscle Skeletal C1orf86 0.20 0.16 lasso 4 0.15 8.0e-15 -5.1 -5.3 1.4e-07 -0.02 0.11 0.89 TRUE
9 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 -5.1 5.2 1.7e-07 0.26 0.13 0.87 FALSE
10 GTEx Muscle Skeletal RP11-181G12.2 0.12 0.13 enet 8 0.14 7.6e-14 -5.1 5.2 1.6e-07 0.00 0.11 0.89 FALSE
11 GTEx Nerve Tibial RP11-181G12.2 0.24 0.22 lasso 5 0.21 3.7e-15 -5.1 5.3 9.0e-08 0.02 0.11 0.89 FALSE
12 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 5.1 5.1 2.7e-07 0.26 0.07 0.93 TRUE
13 GTEx Thyroid PRKCZ 0.16 0.03 lasso 4 0.08 1.9e-06 -4.9 -5.2 2.6e-07 0.04 0.18 0.39 TRUE
14 METSIM Adipose TNFRSF14 0.07 0.05 blup 373 0.05 1.9e-07 4.2 6.3 2.4e-10 -0.01 0.67 0.28 TRUE
15 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 -3.8 5.2 1.8e-07 0.22 0.92 0.06 FALSE