[Hub]/) : Traits : Leg fat-free mass (left) : →

chr1:752,566-3,191,909

Best TWAS P=2.42e-10 · Best GWAS P=1.26e-08 conditioned to NaN

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	4.2	6.3	2.4e-10	-0.01	0.67	0.28	TRUE
1	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-5.1	-6.1	9.4e-10	-0.11	0.11	0.76	TRUE
3	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-5.5	6.0	2.6e-09	0.28	0.02	0.60	TRUE
2	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-2.6	-5.4	8.1e-08	-0.27	0.14	0.16	TRUE
8	GTEx	Muscle Skeletal	C1orf86	0.20	0.16	lasso	4	0.15	8.0e-15	-5.1	-5.3	1.4e-07	-0.02	0.11	0.89	TRUE
13	GTEx	Thyroid	PRKCZ	0.16	0.03	lasso	4	0.08	1.9e-06	-4.9	-5.2	2.6e-07	0.04	0.18	0.39	TRUE
12	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.1	5.1	2.7e-07	0.26	0.07	0.93	TRUE
5	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	4.8	5.7	9.7e-09	0.00	0.13	0.87	FALSE
7	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.0	-5.5	3.2e-08	-0.23	0.07	0.76	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	5.1	5.4	7.7e-08	0.01	0.07	0.39	FALSE
11	GTEx	Nerve Tibial	RP11-181G12.2	0.24	0.22	lasso	5	0.21	3.7e-15	-5.1	5.3	9.0e-08	0.02	0.11	0.89	FALSE
6	GTEx	Lung	AL590822.2	0.09	0.00	lasso	3	0.00	2.0e-01	5.0	5.3	9.8e-08	0.06	0.07	0.25	FALSE
10	GTEx	Muscle Skeletal	RP11-181G12.2	0.12	0.13	enet	8	0.14	7.6e-14	-5.1	5.2	1.6e-07	0.00	0.11	0.89	FALSE
9	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.1	5.2	1.7e-07	0.26	0.13	0.87	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-3.8	5.2	1.8e-07	0.22	0.92	0.06	FALSE