Best TWAS P=3.45e-13 · Best GWAS P=7.2e-15 conditioned to 1.2e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | CDKN2C | 0.14 | 0.11 | enet | 17 | 0.12 | 3.0e-05 | 7.6 | -7.3 | 3.4e-13 | -0.86 | 0.02 | 0.94 | TRUE |
2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 5.7 | -5.8 | 7.8e-09 | 0.02 | 0.89 | 0.01 | TRUE |
3 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 5.2 | -5.5 | 3.6e-08 | 0.10 | 0.01 | 0.99 | TRUE |