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Traits
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Traits
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Leg fat-free mass (left)
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chr10:80,443,273-81,901,722
Best TWAS P=3.67e-11 · Best GWAS P=2.45e-10 conditioned to 1
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ZCCHC24
0.06
0.00
blup
89
0.01
6.2e-02
3.21
6.6
3.7e-11
0.41
0.01
0.11
TRUE
5
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ZCCHC24
0.07
0.05
enet
9
0.04
6.7e-05
6.16
6.5
7.9e-11
0.95
0.00
1.00
TRUE
1
GTEx
Adipose Subcutaneous
ZCCHC24
0.12
0.01
lasso
6
0.03
3.4e-03
5.80
6.6
4.1e-11
0.78
0.01
0.95
FALSE
2
GTEx
Skin Sun Exposed Lower leg
ZCCHC24
0.09
0.00
enet
18
0.00
2.3e-01
0.65
6.6
5.7e-11
0.43
0.02
0.64
FALSE
3
GTEx
Skin Sun Exposed Lower leg
RP11-342M3.5
0.08
0.00
enet
28
0.01
7.3e-02
1.55
5.5
4.5e-08
0.30
0.04
0.28
FALSE