[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr10:75,189,586-80,383,574

Best TWAS P=7.63e-10 · Best GWAS P=1.63e-10 conditioned to 0.000112

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	C10orf11	0.24	0.21	lasso	9	0.20	3.3e-16	5.4	-5.9	4.1e-09	0.03	0.02	0.98	FALSE
2	GTEx	Adipose Visceral Omentum	C10orf11	0.40	0.32	enet	11	0.27	2.2e-14	5.4	-6.0	1.6e-09	0.02	0.02	0.98	FALSE
3	GTEx	Adipose Visceral Omentum	DLG5	0.26	0.23	lasso	8	0.21	5.7e-11	-5.2	-5.1	2.9e-07	0.79	0.46	0.54	FALSE
4	GTEx	Adrenal Gland	C10orf11	0.24	0.22	enet	21	0.18	5.8e-07	5.4	-5.3	1.4e-07	0.02	0.02	0.98	FALSE
5	GTEx	Adrenal Gland	DLG5	0.22	0.14	lasso	6	0.11	8.5e-05	-5.2	-5.5	4.1e-08	0.74	0.29	0.52	FALSE
6	GTEx	Artery Aorta	DLG5	0.26	0.19	enet	10	0.22	2.6e-12	-4.9	-5.5	2.9e-08	0.82	0.38	0.62	FALSE
7	GTEx	Artery Aorta	RP13-39P12.3	0.14	0.13	enet	9	0.12	2.2e-07	-4.9	-5.4	6.8e-08	0.82	0.08	0.92	FALSE
8	GTEx	Artery Tibial	DLG5	0.24	0.18	lasso	5	0.18	9.7e-14	-5.2	-5.1	3.1e-07	0.79	0.52	0.48	FALSE
9	GTEx	Cells Transformed fibroblasts	DLG5	0.25	0.18	lasso	11	0.16	2.0e-12	-5.3	-5.4	5.1e-08	0.83	0.17	0.83	FALSE
10	GTEx	Esophagus Muscularis	C10orf11	0.45	0.39	enet	42	0.38	5.1e-24	5.4	-6.1	1.4e-09	0.01	0.04	0.96	FALSE
11	GTEx	Heart Atrial Appendage	DLG5	0.32	0.23	lasso	4	0.24	3.9e-11	-5.0	-5.2	2.4e-07	0.82	0.52	0.48	FALSE
12	GTEx	Lung	C10orf11	0.30	0.26	lasso	5	0.24	2.0e-18	5.4	-5.9	4.4e-09	0.03	0.02	0.98	FALSE
13	GTEx	Lung	DLG5	0.41	0.38	lasso	8	0.37	7.9e-30	-5.2	-5.2	1.7e-07	0.82	0.54	0.46	FALSE
14	GTEx	Nerve Tibial	DLG5	0.51	0.44	lasso	6	0.50	1.4e-39	-5.2	-5.6	2.8e-08	0.86	0.53	0.47	TRUE
15	GTEx	Nerve Tibial	RP13-39P12.3	0.31	0.25	lasso	7	0.36	1.3e-26	-5.2	-5.2	2.3e-07	0.80	0.25	0.75	FALSE
16	GTEx	Ovary	DLG5	0.62	0.38	lasso	6	0.40	5.3e-11	-5.3	-5.5	4.3e-08	0.76	0.50	0.49	FALSE
17	GTEx	Ovary	RP13-39P12.3	0.42	0.29	lasso	5	0.33	7.5e-09	-5.3	-5.3	9.7e-08	0.75	0.41	0.47	FALSE
18	GTEx	Pancreas	DLG5	0.39	0.43	enet	11	0.44	3.5e-20	-5.2	-5.1	2.7e-07	0.80	0.54	0.46	FALSE
19	GTEx	Pancreas	RP13-39P12.3	0.20	0.24	lasso	3	0.23	3.8e-10	-5.2	-5.2	2.4e-07	0.79	0.49	0.50	FALSE
20	GTEx	Pituitary	DLG5	0.45	0.36	lasso	11	0.31	1.9e-08	-5.3	-5.4	6.6e-08	0.83	0.06	0.93	FALSE
21	GTEx	Pituitary	RP13-39P12.3	0.38	0.22	lasso	11	0.17	3.8e-05	-5.3	-5.3	9.0e-08	0.83	0.03	0.93	FALSE
22	GTEx	Skin Sun Exposed Lower leg	DLG5	0.12	0.06	lasso	4	0.06	4.9e-06	-5.2	-5.2	2.4e-07	0.78	0.28	0.70	FALSE
23	GTEx	Spleen	DLG5	0.51	0.46	lasso	4	0.44	1.1e-12	-5.2	-5.2	1.9e-07	0.80	0.43	0.56	FALSE
24	GTEx	Spleen	RP13-39P12.3	0.38	0.34	lasso	2	0.35	8.8e-10	-5.2	-5.1	3.0e-07	0.76	0.29	0.69	FALSE
25	GTEx	Stomach	DLG5	0.20	0.12	lasso	7	0.08	1.3e-04	-5.2	-5.1	2.7e-07	0.79	0.32	0.60	FALSE
26	GTEx	Thyroid	C10orf11	0.38	0.21	lasso	9	0.25	6.7e-19	5.1	-6.2	7.6e-10	0.02	0.05	0.95	TRUE
27	GTEx	Thyroid	DLG5	0.39	0.43	lasso	5	0.43	1.5e-35	-5.2	-5.1	2.7e-07	0.79	0.55	0.45	FALSE
28	GTEx	Thyroid	RP13-39P12.3	0.28	0.30	lasso	8	0.29	3.3e-22	-5.2	-5.2	1.9e-07	0.79	0.54	0.46	FALSE
29	METSIM	Adipose	C10orf11	0.11	0.10	enet	14	0.10	1.1e-14	5.1	-5.4	6.7e-08	0.02	0.08	0.92	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	ZNF503-AS2	0.07	0.06	lasso	2	0.06	2.2e-08	4.9	5.2	2.2e-07	0.02	0.31	0.69	FALSE
31	YFS	Blood	AP3M1	0.27	0.11	lasso	5	0.15	1.5e-45	4.0	5.3	1.1e-07	-0.01	0.91	0.07	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	VCL	0.02	0.00	blup	57	0.01	5.7e-04	5.6	-5.4	8.7e-08	-0.06	0.01	0.89	FALSE
33	The Cancer Genome Atlas	Lung Adenocarcinoma	VCL	0.04	0.03	lasso	1	0.02	5.8e-04	5.5	-5.5	3.0e-08	-0.08	0.01	0.94	TRUE
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	VCL	0.08	0.06	blup	56	0.07	1.5e-07	5.6	-5.2	2.4e-07	-0.08	0.00	1.00	FALSE