[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr10:123,438,113-124,889,817

Best TWAS P=2.38e-14 · Best GWAS P=1.87e-11 conditioned to 0.795

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	METSIM	Adipose	PLEKHA1	0.05	0.03	lasso	4	0.04	3.6e-07	6.7	-7.6	2.4e-14	-0.86	0.01	0.99	TRUE
1	GTEx	Adipose Subcutaneous	PLEKHA1	0.14	0.06	lasso	2	0.03	2.4e-03	6.7	-6.8	1.3e-11	-0.99	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	PLEKHA1	0.08	0.10	lasso	1	0.09	3.5e-09	6.6	-6.6	3.2e-11	-0.99	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	PLEKHA1	0.04	0.05	lasso	2	0.04	4.3e-05	6.7	-6.6	3.3e-11	-1.00	0.01	0.99	FALSE
4	GTEx	Skin Sun Exposed Lower leg	PLEKHA1	0.16	0.02	lasso	5	0.01	4.0e-02	-6.4	-6.6	3.8e-11	-0.61	0.05	0.89	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	PLEKHA1	0.06	0.05	lasso	4	0.05	1.3e-06	-6.5	-6.5	9.1e-11	-0.77	0.03	0.97	FALSE
3	GTEx	Nerve Tibial	PLEKHA1	0.22	0.23	enet	17	0.19	1.1e-13	6.7	-6.3	3.7e-10	-0.97	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PLEKHA1	0.08	0.06	blup	103	0.02	4.0e-02	6.7	-5.8	5.5e-09	-0.93	0.01	0.87	FALSE
2	GTEx	Muscle Skeletal	PLEKHA1	0.10	0.04	lasso	3	0.04	8.2e-05	-6.5	-5.8	5.7e-09	-0.68	0.05	0.94	FALSE
9	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARMS2	0.06	0.04	blup	71	0.05	4.9e-06	-6.5	-5.6	1.7e-08	-0.75	0.01	0.98	FALSE