[Hub]/) : Traits : Leg fat-free mass (left) :

chr11:64,407,419-66,333,072

Best TWAS P=7.46e-09 · Best GWAS P=3.09e-09 conditioned to 0.000247

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FIBP 0.08 0.11 enet 20 0.12 8.1e-14 3.6 5.2 2.2e-07 -0.47 0.99 0.01 FALSE
2 GTEx Brain Cerebellar Hemisphere EFEMP2 0.35 0.15 enet 5 0.09 2.2e-03 5.3 5.6 1.7e-08 -0.33 0.08 0.79 FALSE
3 GTEx Brain Cerebellum EFEMP2 0.45 0.40 enet 8 0.39 1.6e-12 5.1 5.4 8.4e-08 -0.31 0.12 0.88 FALSE
4 GTEx Cells Transformed fibroblasts EFEMP2 0.06 0.06 lasso 3 0.07 7.8e-06 5.4 5.6 2.3e-08 -0.27 0.10 0.87 FALSE
5 GTEx Colon Transverse DPF2 0.19 0.01 lasso 4 0.05 1.6e-03 3.3 5.5 4.2e-08 -0.07 0.08 0.11 TRUE
6 The Cancer Genome Atlas Breast Invasive Carcinoma EFEMP2 0.04 0.02 lasso 5 0.02 1.4e-05 5.5 5.4 6.9e-08 -0.35 0.04 0.96 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme CTSW 0.16 0.18 enet 16 0.19 2.3e-06 5.0 -5.8 7.5e-09 0.37 0.11 0.77 TRUE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DKFZp761E198 0.07 0.02 blup 39 0.03 5.9e-04 -4.7 -5.4 6.5e-08 0.55 0.02 0.62 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma DPF2 0.03 0.02 blup 28 0.02 1.2e-03 -4.9 5.2 2.1e-07 -0.12 0.00 0.88 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma EFEMP2 0.01 0.00 blup 45 0.01 3.0e-02 2.5 5.1 3.0e-07 -0.37 0.04 0.16 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma FIBP 0.02 0.01 blup 45 0.02 1.3e-03 3.8 5.3 1.5e-07 -0.43 0.06 0.52 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma POLA2 0.12 0.03 enet 9 0.05 2.5e-04 -4.9 5.1 2.7e-07 -0.16 0.01 0.62 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma SNX32 0.08 0.08 lasso 2 0.10 1.5e-06 5.4 5.3 1.3e-07 -0.29 0.07 0.92 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma FIBP 0.04 0.00 blup 45 0.02 8.0e-03 3.6 5.1 2.9e-07 -0.35 0.02 0.06 FALSE